Publications by Geoffrey Taylor - ePrints

Browsing publications by Geoffrey Taylor.

Newcastle Authors	Title	Year
Professor Laura Greaves Marco Nooteboom Dr Joanna Elson Dr Helen Tuppen Geoffrey Taylor et al.	Clonal Expansion of Early to Mid-Life Mitochondrial DNA Point Mutations Drives Mitochondrial Dysfunction during Human Ageing	2014
Professor Laura Greaves Dr Joanna Elson Dr John Grady Geoffrey Taylor Professor Robert Taylor et al.	Comparison of Mitochondrial Mutation Spectra in Ageing Human Colonic Epithelium and Disease: Absence of Evidence for Purifying Selection in Somatic Mitochondrial DNA Point Mutations	2012
Dr Patrick Yu Wai Man Dr Gillian Borthwick Dr Langping He Geoffrey Taylor Professor Laura Greaves et al.	Somatic Mitochondrial DNA Deletions Accumulate to High Levels in Aging Human Extraocular Muscles	2010
Professor Laura Greaves Nina Beadle Geoffrey Taylor Dr Daniel Commane Professor John Mathers et al.	Quantification of mitochondrial DNA mutation load	2009
Dr Amy Reeve Geoffrey Taylor Dr Joanna Elson Professor Robert Taylor Dr Christopher Morris et al.	The low abundance of clonally expanded mitochondrial DNA point mutations in aged substantia nigra neurons	2009
Geoffrey Taylor Professor Pamela Shaw Emeritus Professor Doug Turnbull Professor Robert Taylor	Investigation of the mitochondrial genome in patients with atypical motor neuron disease	2007
Professor Gareth Veal Mike Cole Geoffrey Taylor Julie Errington Professor Alan Boddy et al.	Pharmacogenetics and metabolism of cyclophosphamide in paediatric cancer patients	2007
Dr Christopher Morris Geoffrey Taylor Dr Amy Reeve Emeritus Professor Robert Perry Dr Evelyn Jaros et al.	High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease	2006
Dr Gillian Borthwick Professor Robert Taylor Dr Timothy Walls Dr Kasia Tonska Geoffrey Taylor et al.	Motor neuron disease in a patient with a mitochondrial tRNA^lle mutation	2006
Dr Debbie Pye Dimitra-Smaragda Kyriakouli Geoffrey Taylor Dr Matthias Elstner Professor Zofia Chrzanowska-Lightowlers et al.	Production of transmitochondrial cybrids containing naturally occurring pathogenic mtDNA variants	2006
Professor John Bond Mark Barrow Dr Sally Lynch Merajuddin Ahmed Geoffrey Taylor et al.	The importance of seeking ALMS1 mutations in infants with dilated cardiomyopathy	2005
Professor Robert Taylor Dr Langping He Professor Laura Greaves Geoffrey Taylor Dr Martin Barron et al.	Mitochondrial DNA mutations in human colonic crypt stem cells	2004
Professor Robert Taylor Professor Patrick Chinnery Geoffrey Taylor Emeritus Professor Doug Turnbull	Genotypes from patients indicate no paternal mitochondrial DNA contribution	2003
Professor Robert Taylor Dr Martin Barron Dr Gillian Borthwick Professor Patrick Chinnery Dr David Samuels et al.	Mitochondrial DNA mutations and aging in human colonic crypts and stem cells	2003
Professor Robert Taylor Dr Martin Barron Dr Gillian Borthwick Professor Patrick Chinnery Dr David Samuels et al.	Mitochondrial DNA mutations in human colonic crypt stem cells	2003
Dr Stephen Lynn Geoffrey Taylor Dr Theresa Wardell Professor Patrick Chinnery Emeritus Professor Doug Turnbull et al.	Defining the importance of mitochondrial gene defects in maternally inherited diabetes by sequencing the entire mitochondrial genome	2002
Professor Herbie Newell Professor Alan Boddy Geoffrey Taylor Andrew Johnston Professor Andrew Pearson et al.	A phase I study of nolatrexed dihydrochloride in children with advanced cancer. A United Kingdom Children's Cancer Study Group Investigation	2001
Dr Brian Moore Geoffrey Taylor Emeritus Professor Nicol Ferrier Professor Jim Edwardson	Absorption of aluminium-26 in Alzheimer's disease, measured using accelerator mass spectrometry	2000
Geoffrey Taylor Professor Jim Edwardson Dr Christopher Morris	Brain oestradiol and testosterone levels in Alzheimer's disease	2000
Professor Patrick Chinnery Geoffrey Taylor Dr Richard Andrews Dr Christopher Morris Professor Robert Taylor et al.	Mitochondrial DNA haplogroups and susceptibility to AD and dementia with Lewy bodies	2000
Dr David Cottrell Dr Emma Watson Dr Gillian Borthwick Dr Margaret Johnson Geoffrey Taylor et al.	Role of mitochondrial DNA mutations in disease and aging	2000
Dr Andrew Hall Professor John Lunec Professor Herbie Newell Professor Andrew Pearson Geoffrey Taylor et al.	Thymidylate synthase expression in nolatrexed and methotrexate-resistant human leukaemia cell lines	1998
Geoffrey Taylor Dr Christopher Morris Emeritus Professor Robert Perry Professor Jim Edwardson Patricia Harrison et al.	Iron and aluminium in relation to brain ferritin in normal individuals and Alzheimer's-disease and chronic renal-dialysis patients	1992
Geoffrey Taylor Professor Alan Calvert	ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study	1991
Professor Herbie Newell Geoffrey Taylor Professor Alan Calvert	The biochemical pharmacology of the thymidylate synthase inhibitor, 2-desamino-2-methyl-N¹⁰-propargyl-5,8-dideazafolic acid (ICI 198583)	1991
Geoffrey Taylor Professor Alan Calvert	Activity of the thymidylate synthase inhibitor 2-desamino-N-¹⁰- propargyl-5,8-dideazafolic acid and related-compounds in murine (L1210) and human (W1l2) systems in Vitro and in L1210 in Vivo	1990
Geoffrey Taylor Professor Alan Calvert	Estimation of the in vitro and in vivo inhibitory effects of antifolates upon thymidylate synthase (TS) in whole cells	1989
Geoffrey Taylor Professor Alan Calvert	Modulation of anti-metabolite effects: effects of thymidine on the efficacy of the quinazoline based thymidylate synthetase inhibitor, CB3717	1984
Geoffrey Taylor Professor Alan Calvert	Plasma nucleoside and base levels following treatment with the new thymidylate synthetase inhibitor-CB-3717	1984
Geoffrey Taylor Professor Alan Calvert	Methotrexate with thymidine, inosine, and allopurinol rescue - a phase-I clinical-study	1981