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Falls and Fall-Related Injury Are Common in Older People with Chronic Liver Disease

Lookup NU author(s): Dr James FrithORCiD, Sandra Kerr, Dr Lisa Robinson, Chris Elliott, Katharine Wilton, Professor David Jones, Professor Chris Day, Emerita Professor Julia Newton


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Improved survival with chronic liver disease (CLD) and increased incidence in the older has led to a rapidly expanding population which faces similar "geriatric syndromes" as the general population. With risk factors such as autonomic dysfunction, cognitive impairment, and muscle abnormalities in CLD it is expected that falls and injury will be common. To determine prevalence of falls and injury in chronic liver disease and to identify potential modifiable fall associations. Falls prevalence was estimated by providing patients aged a parts per thousand yen65 years with CLD a falls data collection tool, via the post or in the clinic. A younger CLD cohort and age-matched and sex-matched community controls was used for comparison. A sub-group underwent multidisciplinary falls assessment to identify modifiable fall associations. Falls were significantly more common in older people with CLD (47 % in previous year) than in controls; incidence of injury did not differ. Regression identified orthostatic symptoms, lower-limb strength, and fear of falling as being independently associated with falls in CLD. Those who had fallen had significantly greater difficulty with daily activities. Falls are prevalent in older people with CLD, and are potentially preventable with multifactorial intervention. Services must prepare for expansion in the older CLD population; here we demonstrate how this expansion may affect falls services and provide a potential therapeutic target.

Publication metadata

Author(s): Frith J, Kerr S, Robinson L, Elliott CS, Wilton K, Jones DEJ, Day CP, Newton JL

Publication type: Article

Publication status: Published

Journal: Digestive Diseases and Sciences

Year: 2012

Volume: 57

Issue: 10

Pages: 2697-2702

Print publication date: 01/10/2012

ISSN (print): 0163-2116

ISSN (electronic): 1573-2568

Publisher: Springer New York LLC


DOI: 10.1007/s10620-012-2193-5


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