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Browsing publications by Professor Chris Day.

Newcastle AuthorsTitleYearFull text
Dr Rebecca Darlay
Professor Heather Cordell
Professor Ann Daly
Professor Chris Day
Dr Steven Masson
et al.
Corrigendum to: 'A genetic risk score and diabetes predict development of alcohol-related cirrhosis in drinkers' [J Hepatol 2022 (76) 275–282] (Journal of Hepatology (2022) 76(2) (275–282), (S0168827821021115), (10.1016/j.jhep.2021.10.005))2022
Dr Olivier Govaere
Dr Rebecca Darlay
Dr Julien Peltier
Dr Jeremy Palmer
Dr Massimo Younes
et al.
Macrophage Scavenger Receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease2022
Dr Rebecca Darlay
Dr Steven Masson
Professor Chris Day
Professor Ann Daly
Professor Heather Cordell
et al.
Genome-wide association study and meta-analysis on alcohol-related liver cirrhosis identifies novel genetic risk factors2021
Dr Steven Masson
Professor Ann Daly
Professor Heather Cordell
Professor Chris Day
Obesity, Diabetes, Coffee, Tea, and Cannabis Use Alter Risk for Alcohol-Related Cirrhosis in 2 Large Cohorts of High-Risk Drinkers2021
Professor Quentin Anstee
Dr Rebecca Darlay
Dr Simon Cockell
Dr Olivier Govaere
Dr Dina Tiniakos
et al.
Genome-Wide Association Study of Non-Alcoholic Fatty Liver and Steatohepatitis in a Histologically-Characterised Cohort2020
Dr Timothy Hardy
Kristy Wonders
Dr Massimo Younes
Professor Pierre Bedossa
Entesar Betelmal
et al.
The European NAFLD Registry: a real-world longitudinal cohort study of nonalcoholic fatty liver disease2020
Dr Olivier Govaere
Dr Simon Cockell
Dr Dina Tiniakos
Dr Rachel Queen
Dr Massimo Younes
et al.
Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis2020
Professor Chris Day
Professor Alastair Burt
Systems Genetics of Hepatic Metabolome Reveals Octopamine as a Target for Non-Alcoholic Fatty Liver Disease Treatment2019
Dr Dave Houghton
Dr Kate Hallsworth
Dr Sophie Cassidy
Christian Thoma
Dr Leah Avery
et al.
The degree of hepatic steatosis associates with impaired cardiac and autonomic function2019
Dr Steven Masson
Professor Ann Daly
Professor Heather Cordell
Professor Chris Day
Evaluation of laboratory tests for cirrhosis and for alcohol use, in the context of alcoholic cirrhosis2018
Professor Quentin Anstee
Professor Chris Day
Professor Arun Sanyal
Modeling NAFLD Disease Burden in China, France, Germany, Italy, Japan, Spain, United Kingdom, and United States for the period 2016-20302018
Dr Dave Houghton
Dr Timothy Hardy
Professor Christopher Stewart
Linda Errington
Professor Chris Day
et al.
Systematic review assessing the effectiveness of dietary intervention on gut microbiota in adults with type 2 diabetes2018
Professor Stuart McPherson
Dr Nina Wilson
Dr Dina Tiniakos
Dr Jennifer Wilkinson
Professor Alastair Burt
et al.
A randomised controlled trial of losartan as an anti-fibrotic agent in non-alcoholic steatohepatitis2017
Professor Stuart McPherson
Dr Timothy Hardy
Dr Dina Tiniakos
Professor Alastair Burt
Professor Chris Day
et al.
Age as a Confounding Factor for the Accurate Non-Invasive Diagnosis of Advanced NAFLD Fibrosis2017
Dr Sally Coulthard
Professor Chris Day
Professor Ann Daly
Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study2017
Dr Dave Houghton
Dr Sophie Cassidy
Dr Christian Thoma
Dr Kate Hallsworth
Dr Leah Avery
et al.
Autonomic function is impaired across the spectrum of NAFLD2017
Dr Mikolaj Ogrodnik
Dr Satomi Miwa
Dr Dina Tiniakos
Dr Caroline Wilson
Professor Chris Day
et al.
Cellular senescence drives age-dependent hepatic steatosis2017
Dr Dave Houghton
Dr Kate Hallsworth
Dr Christian Thoma
Dr Sophie Cassidy
Dr Timothy Hardy
et al.
Effects of Exercise on Liver Fat and Metabolism in Alcohol Drinkers2017
Dr Dave Houghton
Christian Thoma
Dr Kate Hallsworth
Dr Sophie Cassidy
Dr Timothy Hardy
et al.
Exercise Reduces Liver Lipids and Visceral Adiposity in Patients With Nonalcoholic Steatohepatitis in a Randomized Controlled Trial2017
Dr Timothy Hardy
Dr Mujdat Zeybel
Professor Chris Day
Dr Christian Dipper
Dr Steven Masson
et al.
Plasma DNA methylation: A potential biomarker for stratification of liver fibrosis in non-alcoholic fatty liver disease2017
Professor Quentin Anstee
Dr Yang-Lin Liu
Dr Rebecca Darlay
Professor Heather Cordell
Professor Ann Daly
et al.
Transcriptional regulation of PNPLA3 and its impact on susceptibility to nonalcoholic fatty liver Disease (NAFLD) in humans2017
Dr Dina Tiniakos
Professor Quentin Anstee
Professor Chris Day
Professor Alastair Burt
Dr John Brain
et al.
Diagnostic performance of FibroTest, SteatoTest and ActiTest in patients with NAFLD using the SAF score as histological reference2016
Dr Dave Houghton
Dr Sophie Cassidy
Dr Kate Hallsworth
Dr Kieren Hollingsworth
Professor Roy Taylor
et al.
Exercise reduces liver fat and improves body composition but not insulin sensitivity or inflammatory markers in non-alcoholic steatohepatitis2016
Professor Quentin Anstee
Professor Chris Day
Genetic Factors That Affect Risk of Alcoholic and Nonalcoholic Fatty Liver Disease2016
Dr Dave Houghton
Professor Chris Day
Professor Mike Trenell
Gut microbiota and lifestyle interventions in NAFLD2016
Professor Helen Reeves
Marco Zaki
Professor Chris Day
Hepatocellular Carcinoma in Obesity, Type 2 Diabetes, and NAFLD2016
Dr Nimantha de Alwis
Professor Quentin Anstee
Professor Chris Day
How to Diagnose Nonalcoholic Fatty Liver Disease2016
Dr Timothy Hardy
Professor Fiona Oakley
Professor Quentin Anstee
Professor Chris Day
Nonalcoholic Fatty Liver Disease: Pathogenesis and Disease Spectrum2016
Professor Chris Day
Physical activity is prospectively associated with adolescent nonalcoholic fatty liver disease2016
Professor Ann Daly
Professor Chris Day
Variants in the LGALS9 Gene Are Associated With Development of Liver Disease in Heavy Consumers of Alcohol2016
Professor Chris Day
Dr Steven Masson
Professor Ann Daly
Professor Heather Cordell
Brief Report: Genetics of Alcoholic Cirrhosis-GenomALC Multinational Study2015
Dr Sophie Cassidy
Dr Kate Hallsworth
Dr Christian Thoma
Dr Guy MacGowan
Dr Kieren Hollingsworth
et al.
Cardiac structure and function are altered in type 2 diabetes and Non-alcoholic fatty liver disease and associate with glycemic control2015
Professor Chris Day
Childhood Energy Intake Is Associated with Nonalcoholic Fatty Liver Disease in Adolescents2015
Anna Whitehead
Dr Gillian Patman
Professor Chris Day
Dr Dina Tiniakos
Professor Quentin Anstee
et al.
Effects of FXR agonist PX20606 on tumour formation in animal models of non-alcoholic fatty liver disease2015
Professor Stuart McPherson
Dr Timothy Hardy
Elsbeth Henderson
Professor Alastair Burt
Professor Chris Day
et al.
Evidence of NAFLD progression from steatosis to fibrosing-steatohepatitis using paired biopsies: Implications for prognosis and clinical management2015
Dr Dave Houghton
Dr Christian Thoma
Dr Kate Hallsworth
Dr Kieren Hollingsworth
Professor Chris Day
et al.
Exercise reduces liver fat, visceral fat and circulating triglycerides, but not circulating inflammatory markers in non-alcoholic steatohepatitis2015
Professor Quentin Anstee
Professor Ann Daly
Professor Chris Day
Genetics of Alcoholic Liver Disease2015
Dr Sophie Cassidy
Christian Thoma
Dr Kate Hallsworth
Dr Jehill Parikh
Dr Kieren Hollingsworth
et al.
High intensity intermittent training improves cardiac function and reduces liver fat in adults with Type 2 diabetes: an MRI/S study2015
Professor Stuart McPherson
Dr Timothy Hardy
Professor Alastair Burt
Professor Chris Day
Professor Quentin Anstee
et al.
High rate of false positives for advanced fibrosis when simple non-invasive fibrosis tests are used in older patients (>=65 years) with NAFLD2015
Dr Jeremy Palmer
Dr Yang-Lin Liu
Professor Chris Day
Professor Ann Daly
Professor Quentin Anstee
et al.
Mechanistic Study of TM6SF2 in NAFLD pathogenesis: Stably transfected Huh7 cells over-expressing the TM6SF2 E167K variant exhibit greater levels of oxidative stress2015
Dr Kate Hallsworth
Christian Thoma
Dr Kieren Hollingsworth
Dr Sophie Cassidy
Professor Quentin Anstee
et al.
Modified high-intensity interval training reduces liver fat and improves cardiac function in non-alcoholic fatty liver disease: A randomised controlled trial2015
Professor Chris Day
Nonalcoholic fatty liver disease2015
Professor Chris Day
Professor Quentin Anstee
Nonalcoholic Fatty Liver Disease: Foreword2015
Dr Timothy Hardy
Professor Quentin Anstee
Professor Chris Day
Nonalcoholic fatty liver disease: new treatments2015
Dr Sarah Wiscombe
Emerita Professor Julia Newton
Professor Chris Day
Emeritus Professor John Gibson
Dr Sophie West
et al.
Obstructive sleep apnoea is common in adults with biopsy-proven non-alcoholic fatty liver disease2015
Professor Ann Daly
Professor Chris Day
PNPLA3 Gene Polymorphism Is Associated With Predisposition to and Severity of Alcoholic Liver Disease2015
Professor Chris Day
Dr Steven Masson
Prednisolone or Pentoxifylline for Alcoholic Hepatitis2015
Professor Quentin Anstee
Dr Yang-Lin Liu
Professor Chris Day
Professor Helen Reeves
Reply to: HCC and liver disease risk in homozygous PNPLA3 p.I148M carriers approach monogenic inheritance2015
Professor Chris Day
Professor Pierre Bedossa
Substantial variability of the diagnostic accuracy of serum fibrosis markers across multiple cohorts of nash patients in various centers : the case for the negative predictive value2015
Professor Chris Day
The association of nonalcoholic fatty liver disease with central and peripheral blood pressure in adolescence: Findings from a cross-sectional study2015
Michelle Thursby
Professor Chris Day
Ellen Allison
Dr Steven Masson
Professor Luke Vale
et al.
The clinical effectiveness and cost-effectiveness of STeroids or Pentoxifylline for Alcoholic Hepatitis (STOPAH): a 2x2 factorial, randomised controlled trial.2015
Rodolphe Anty
Professor Chris Day
Professor Ann Daly
Anh Tran
Professor Quentin Anstee
et al.
The FNDC5 rs3480 is protective on the steatosis and fibrosis in patients with NAFLD2015
Professor Quentin Anstee
Professor Chris Day
The Genetics of Nonalcoholic Fatty Liver Disease: Spotlight on PNPLA3 and TM6SF22015
Professor Ann Daly
Professor Chris Day
Dr Yang-Lin Liu
Professor Quentin Anstee
TM6SF2 as a Genetic Risk Factor for Fibrosis2015
Dr Yang-Lin Liu
Professor Ann Daly
Professor Chris Day
Professor Quentin Anstee
TM6SF2: Catch-22 in the Fight Against Nonalcoholic Fatty Liver Disease and Cardiovascular Disease?2015
Professor Quentin Anstee
Professor Chris Day
Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis2015
Ching Ng
Dr Abul Hasnat
Professor Chris Day
Professor Ann Daly
N-acetyltransferase 2 (NAT2) genotype as a risk factor for development of drug-induced liver injury relating to antituberculosis drug treatment in a mixed-ethnicity patient group2014
Dr Yang-Lin Liu
Dr Gillian Patman
Julian Leathart
Professor Alastair Burt
Professor Chris Day
et al.
Carriage of the PNPLA3 rs738409 C>G Polymorphism Confers an Increased Risk of Non-Alcoholic Fatty Liver Disease Associated Hepatocellular Carcinoma2014
Dr Steven Masson
Ingrid Emmerson
Elsbeth Henderson
Dr Emma Fletcher
Professor Alastair Burt
et al.
Clinical but not histological factors predict long-term prognosis in patients with histologically advanced non-decompensated alcoholic liver disease2014
Julian Leathart
Professor Ann Daly
Professor Chris Day
Professor Quentin Anstee
Gene Polymorphisms of Cellular Senescence Marker P21 and Disease Progression in Non-Alcohol-Related Fatty Liver Disease2014
Professor Chris Day
Lack of Efficacy of an Inhibitor of PDE4 in Phase 1 and 2 Trials of Patients With Nonalcoholic Steatohepatitis2014
Professor Stuart McPherson
Elsbeth Henderson
Dr Timothy Hardy
Professor Alastair Burt
Professor Chris Day
et al.
Natural history of NAFLD: A study of 108 patients with paired liver biopsies2014
Professor Stuart McPherson
Dr Timothy Hardy
Professor Alastair Burt
Professor Chris Day
Professor Quentin Anstee
et al.
Natural History of NAFLD: A Study of 108 Patients with Paired Liver Biopsies2014
Dr Kate Hallsworth
Dr Christian Thoma
Sarah Moore
Dr Thomas Ploetz
Professor Quentin Anstee
et al.
Non-alcoholic fatty liver disease is associated with higher levels of objectively measured sedentary behaviour and lower levels of physical activity than matched healthy controls2014
Beth Anderson
Professor Chris Day
Nonalcoholic fatty liver disease, liver fibrosis, and cardiometabolic risk factors in adolescence: A cross- Sectional study of 1874 general population adolescents2014
Dr James Frith
Professor Fai Ng
Professor Chris Day
Dr Brendan Payne
Professor Neil Sheerin
et al.
Orthostatic intolerance is common in chronic disease - A clinical cohort study2014
Professor Chris Day
Serum Ferritin Levels Lack Diagnostic Accuracy for Liver Fibrosis in Patients With Nonalcoholic Fatty Liver Disease2014
Professor Stuart McPherson
Elsbeth Henderson
Professor Alastair Burt
Professor Chris Day
Professor Quentin Anstee
et al.
Serum immunoglobulin levels predict fibrosis in patients with non-alcoholic fatty liver disease2014
Professor Chris Day
Dr Steven Masson
Steroids or Pentoxifylline for Alcoholic Hepatitis: Results of the STOPAH Trial2014
Dr Yang-Lin Liu
Professor Helen Reeves
Professor Alastair Burt
Dr Dina Tiniakos
Professor Stuart McPherson
et al.
TM6SF2 rs58542926 Influences Hepatic Fibrosis Progression in Patients with Non-Alcoholic Fatty Liver Disease2014
Dr Jess Dyson
Professor Chris Day
Treatment of Non-Alcoholic Fatty Liver Disease2014
Professor Chris Day
Weight trajectories through infancy and childhood and the risk of non-alcoholic fatty liver disease in adolescence: The ALSPAC study2014
Professor Quentin Anstee
Dr Rebecca Darlay
Julian Leathart
Yilei Liu
Professor Alastair Burt
et al.
A candidate-gene approach to validation of genetic modifier associations using a large cohort with histologically characterised non-alcoholic fatty liver disease2013
Professor Chris Day
A Large Independent Validation Study of Nonivasive Scores to Predict Advanced Fibrosis in NAFLD2013
Anna Whitehead
Dr Gillian Patman
Liam Cornell
Dr Despina Televantou
Professor Nicola Curtin
et al.
A Role for DNA Repair Protein Kinase (DNA-PK) in the Progression of Simple Steatosis to Steatohepatitis (NASH)?2013
Professor Stuart McPherson
Professor Quentin Anstee
Professor Chris Day
Professor Alastair Burt
Are simple noninvasive scoring systems for fibrosis reliable in patients with NAFLD and normal ALT levels?2013
Dr Kate Hallsworth
Dr Kieren Hollingsworth
Dr Christian Thoma
Professor Djordje Jakovljevic
Dr Guy MacGowan
et al.
Cardiac function improves following high intensity intermittent exercise in adults with non-alcoholic fatty liver disease2013
Dr Kate Hallsworth
Dr Kieren Hollingsworth
Dr Christian Thoma
Professor Djordje Jakovljevic
Dr Guy MacGowan
et al.
Cardiac function improves following high intensity intermittent exercise in adults with non-alcoholic fatty liver disease2013
Dr Kate Hallsworth
Dr Kieren Hollingsworth
Dr Christian Thoma
Professor Quentin Anstee
Professor Chris Day
et al.
Cardiac Function Improves Following High Intensity Intermittent Exercise Therapy in Non-Alcoholic Fatty Liver Disease2013
Dr Kate Hallsworth
Dr Kieren Hollingsworth
Dr Christian Thoma
Professor Djordje Jakovljevic
Dr Guy MacGowan
et al.
Cardiac structure and function are altered in adults with non-alcoholic fatty liver disease2013
Dr Yang-Lin LIU
Dr Gillian Patman
Julian Leathart
Professor Alastair Burt
Professor Chris Day
et al.
Carriage of PNPLA3 I148M is Associated with an Increased Risk of Non-Alcoholic Fatty Liver Disease Associated Hepatocellular Carcinoma2013
Professor Chris Day
From NAFLD in clinical practice to answers from guidelines2013
Chris Elliott
Dr James Frith
Professor Chris Day
Professor David Jones
Emerita Professor Julia Newton
et al.
Functional Impairment in Alcoholic Liver Disease and Non-alcoholic Fatty Liver Disease Is Significant and Persists over 3 Years of Follow-Up2013
Professor Ann Daly
Professor Chris Day
Genetic Polymorphisms of Galectin-9 (Gal-9) Associated with Risk of Developing Alcoholic Liver Disease (ALD) in Humans2013
Dr Luca Miele
Professor Chris Day
Gut-liver Axis and Microbiota in NAFLD: Insight Pathophysiology for Novel Therapeutic Target2013
Dr Kate Hallsworth
Dr Christian Thoma
Professor Quentin Anstee
Professor Chris Day
Professor Mike Trenell
et al.
Higher Objectively Measured Sedentary Behaviour and Lower Levels of Physical Activity than Matched Healthy Controls2013
Dr Christian Thoma
Dr Kate Hallsworth
Dr Kieren Hollingsworth
Professor Quentin Anstee
Professor Chris Day
et al.
HIGH-INTENSITY INTERMITTENT EXERCISE THERAPY REDUCES LIVER FAT AND IMPROVES BODY COMPOSITION IN ADULTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE2013
Professor Chris Day
Professor Mark Walker
Professor Helen Reeves
Krüppel Like Factor 6 (KLF6) Protects From NAFLD Progression through Regulation of Adipose Tissue Insulin Resistance2013
Professor Quentin Anstee
Dr Yang-Lin Liu
Professor Heather Cordell
Dr Rebecca Darlay
Professor Chris Day
et al.
Mapping Expression Quantitative Traits Loci (EQTL) for PNPLA3 Gene Identifies Additional SNPs Associated with Non-Alcoholic Fatty Liver Disease (NAFLD) Independent of rs7384092013
Dr Gillian Patman
Dr Despina Televantou
Anna Whitehead
Professor Chris Day
Professor Fiona Oakley
et al.
Mild Steatosis and Impaired Glucose Tolerance are Associated with Liver Cancer Development, While Progression to Nash Increases Number/Size in an Animal Model of NAFLD2013
Dr Stuart Kendrick
Professor Chris Day
Natural history and factors influencing the course of alcohol-related liver disease2013
Professor Quentin Anstee
Professor Chris Day
Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis2013
Professor Djordje Jakovljevic
Dr Kate Hallsworth
Christian Thoma
Professor Chris Day
Emerita Professor Julia Newton
et al.
Resistance exercise improves autonomic regulation at rest and haemodynamic response to exercise in non-alcoholic fatty liver disease2013
Professor Chris Day
Simple Noninvasive Systems Predict Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease2013
Professor Chris Day
Dr Steven Masson
Steroids or pentoxifylline for alcoholic hepatitis (STOPAH): study protocol for a randomised controlled trial2013
Dr Gillian Patman
Dr Despina Televantou
Anna Whitehead
Professor Chris Day
Professor Alastair Burt
et al.
Sulfatase-2 (SULF2) Expressed in Hepatocytes and Stromal Cells Contributes to the Development of Steatosis, the Progression of NAFLD to Fibrosis and the Advancement of Cancer2013
Professor Quentin Anstee
Professor Chris Day
The genetics of NAFLD2013
Dr Christian Thoma
Dr Kate Hallsworth
Dr Kieren Hollingsworth
Professor Roy Taylor
Professor Chris Day
et al.
Unsupervised high-intensity intermittent training reduces liver fat and improves body composition in adults with non-alcoholic fatty liver disease (NAFLD)2013
Professor Alastair Burt
Professor Chris Day
Validation of terminal peptide of procollagen III for the detection and assessment of nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease2013
Dr Timothy Hardy
Dr Christopher Wells
Dr Stuart Kendrick
Professor Chris Day
Professor Alastair Burt
et al.
White cell count and platelet count associate with histological alcoholic hepatitis in jaundiced harmful drinkers2013
Professor Quentin Anstee
Professor Chris Day
S-adenosylmethionine (SAMe) therapy in liver disease: A review of current evidence and clinical utility2012
Professor Quentin Anstee
Professor Chris Day
A lipid to treat non-alcoholic fatty liver disease – The dawn of ‘lipo-rehabilitation’?2012
Professor Alastair Burt
Professor Chris Day
An algorithm combining direct and indirect liver fibrosis tests enhances diagnostic performance for the detection of advanced fibrosis (F3-4) in NAFLD minimising the need for liver biopsy2012
Dr Kate Hallsworth
Dr Kieren Hollingsworth
Dr Christian Thoma
Professor Roy Taylor
Professor Chris Day
et al.
Cardiac structure and function are altered in adults with non-alcoholic fatty liver disease2012
Dr Kate Hallsworth
Dr Kieren Hollingsworth
Dr Christian Thoma
Professor Roy Taylor
Professor Chris Day
et al.
Cardiac structure and function is altered in adults with non-alcoholic fatty liver disease2012
Dr Steven Masson
Ingrid Emmerson
Professor Alastair Burt
Professor Chris Day
Dr Stephen Stewart
et al.
Clinical but not histological factors predict long-term prognosis in patients with biopsy proven advanced alcoholic liver disease2012
Professor Chris Day
Clinical Spectrum and Therapy of Non-Alcoholic Steatohepatitis2012
Dr James Frith
Professor David Jones
Professor Chris Day
Emerita Professor Julia Newton
Cognitive impairment in non-cirrhotic chronic liver disease is unrelated to liver disease severity but associated with ineffective baroreflex function2012
Dr James Frith
Sandra Kerr
Dr Lisa Robinson
Chris Elliott
Katharine Wilton
et al.
Falls and Fall-Related Injury Are Common in Older People with Chronic Liver Disease2012
Professor Ann Daly
Professor Chris Day
Genetic association studies in drug-induced liver injury2012
Professor Quentin Anstee
Dr Rebecca Darlay
Julian Leathart
Professor Helen Reeves
Professor Alastair Burt
et al.
Genome-Wide Association Analysis Confirms Importance of PNPLA3 and Identifies Novel Variants Associated With Histologically Progressive Steatohepatitis in NAFLD2012
Dr Gillian Patman
Laura Pascoe
Dr Luca Miele
Douglas Hui
Professor Alastair Burt
et al.
Glucokinase links Krüppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver disease2012
Professor Chris Day
Guidelines for liver transplantation for patients with non-alcoholic steatohepatitis2012
Dr Christian Thoma
Professor Chris Day
Professor Mike Trenell
Lifestyle interventions for the treatment of non-alcoholic fatty liver disease in adults: A systematic review2012
Dr Kate Hallsworth
Dr Christian Thoma
Sarah Moore
Professor Roy Taylor
Professor Chris Day
et al.
Physical activity levels are lower in people with non-alcoholic fatty liver disease than matched healthy controls2012
Ahmad Alserri
Professor Quentin Anstee
Julian Leathart
Julia Patch
Professor Chris Day
et al.
The SOD2 C47T polymorphism influences NAFLD fibrosis severity: Evidence from case-control and intra-familial allele association studies2012
Professor Stuart McPherson
Dr Timothy Hardy
Professor Alastair Burt
Professor Chris Day
Professor Quentin Anstee
et al.
The FIB-4 score reliability excludes advanced fibrosis in a diabetic cohort with NAFLD2012
Dr Stefano Ballestri
Professor Chris Day
Ultrasonographic fatty liver indicator, a novel score which rules out NASH and is correlated with metabolic parameters in NAFLD2012
Professor Ann Daly
Professor Chris Day
A common polymorphism in the ABCB11 gene is associated with advanced fibrosis in hepatitis C but not in non-alcoholic fatty liver disease2011
Professor Stuart McPherson
Professor Quentin Anstee
Elsbeth Henderson
Professor Alastair Burt
Professor Chris Day
et al.
Are simple non-invasive scoring systems for fibrosis reliable in patients with NAFLD and normal ALT levels?2011
Professor Ann Daly
Dr Stefano Ballestri
Professor Chris Day
Genetic determinants of susceptibility and severity in nonalcoholic fatty liver disease2011
Professor Quentin Anstee
Professor Ann Daly
Professor Chris Day
Genetic modifiers of non-alcoholic fatty liver disease progression2011
Professor Quentin Anstee
Professor Ann Daly
Professor Chris Day
Genetics of alcoholic liver disease and nonalcoholic fatty liver disease2011
Professor Quentin Anstee
Professor Stuart McPherson
Professor Chris Day
How big a problem is non-alcoholic fatty liver disease?2011
Professor Chris Day
Liver Enzymes, Nonalcoholic Fatty Liver Disease, and Incident Cardiovascular Disease2011
Dr Nimantha De Alwis
Julian Leathart
Professor Gavin Hudson
Dr Angela Pyle
Dr Catherine Mowbray
et al.
Mitochondrial DNA does not contribute to the heritability of non-alcoholic fatty liver disease2011
Professor Chris Day
Non-alcoholic fatty liver disease: a massive problem2011
Professor Chris Day
Pathogenesis of alcohol-induced liver disease: Classical concepts and recent advances2011
Dr Stefano Ballestri
Professor Chris Day
Professor Ann Daly
Polymorphism in the Farnesyl Diphosphate Farnesyl Transferase 1 Gene and Nonalcoholic Fatty Liver Disease Severity2011
Professor Alastair Burt
Alison Bray
Professor Chris Day
Recombinant lysosomal acid lipase normalizes liver weight, transaminases and histopathological abnormalities in an in vivo model of cholesteryl ester storage disease2011
Dr Kate Hallsworth
Dr Gulnar Fattakhova
Dr Kieren Hollingsworth
Dr Christian Thoma
Sarah Moore
et al.
Resistance exercise improves liver fat and glucose control in people with non-alcoholic fatty liver disease2011
Dr Kate Hallsworth
Dr Gulnar Fattakhova
Dr Kieren Hollingsworth
Christian Thoma
Sarah Moore
et al.
Resistance exercise improves liver fat and glucose control in people with non-alcoholic fatty liver disease2011
Dr Kate Hallsworth
Dr Gulnar Fattakhova
Dr Kieren Hollingsworth
Dr Christian Thoma
Sarah Moore
et al.
Resistance exercise improves liver lipid, fat oxidation and glucose control in adults with non-alchoholic fatty liver disease independent of weight loss2011
Dr Kate Hallsworth
Dr Kieren Hollingsworth
Dr Christian Thoma
Sarah Moore
Professor Roy Taylor
et al.
Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss2011
Professor Chris Day
Risk of all-cause and cardiovascular mortality in patients with chronic liver disease2011
Professor Chris Day
Dr Peter Donaldson
Professor Ann Daly
Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and class II alleles2011
Dr Eileen Lee
Professor Chris Day
The Natural History of Nonalcoholic Fatty Liver Disease With Advanced Fibrosis or Cirrhosis: An International Collaborative Study2011
Julian Leathart
Professor Ann Daly
Professor Chris Day
The APOC3 T-455C and C-482T promoter region polymorphisms are not associated with the severity of liver damage independently of PNPLA3 I148M genotype in patients with nonalcoholic fatty liver2011
Professor Alastair Burt
Professor Chris Day
Validation of a novel biomarker model for the prediction of non-alcoholic steatohepatitis in patients with non-alcoholic fatty liver disease2011
Professor Chris Day
Vascular adhesion protein-1 promotes progression of steatohepatitis by expansion of the intrahepatic CD4+AND NKT cell populations and induction of fibrogenesis2011
Professor Stuart McPherson
Alison Burt
Professor Chris Day
A comparison of non-invasive fibrosis scoring systems in patients with non-alcoholic fatty liver disease2010
Elise Andrews
Professor Matthew Wright
Professor Chris Day
Professor Ann Daly
A Role for the Pregnane X Receptor in Flucloxacillin-Induced Liver Injury2010
Dr Stuart Kendrick
Dr Graeme O'Boyle
Professor Jelena Mann
Dr Mujdat Zeybel
Dr Jeremy Palmer
et al.
Acetate, the Key Modulator of Inflammatory Responses in Acute Alcoholic Hepatitis2010
Dr Jeremy Palmer
Dr Imran Patanwala
Elsbeth Henderson
Professor Chris Day
Professor David Jones
et al.
Allo- and auto-antibody responses in ALD as biomarkers of prognosis2010
Dr Stuart Kendrick
Professor Chris Day
Can pentoxifylline secure its place in liver therapeutics?2010
Professor Chris Day
Comparison of the Glasgow Alcoholic Hepatitis Score and the ABIC Score for the Assessment of Alcoholic Hepatitis2010
Dr Nimantha De Alwis
Professor Chris Day
Current and Future Therapeutic Strategies in NAFLD2010
Professor Chris Day
Disorders of Coagulation and Hemostasis in Abdominal Obesity: Emerging Role of Fatty Liver2010
Professor Alastair Burt
Professor Chris Day
Elevated endotoxin levels in non-alcoholic fatty liver disease2010
Professor Chris Day
Enhanced liver fibrosis test can predict clinical outcomes in patients with chronic liver disease2010
Professor Chris Day
Genetic and environmental susceptibility to non-alcoholic fatty liver disease2010
Professor Chris Day
Genetic and Environmental Susceptibility to Non-Alcoholic Fatty Liver Disease2010
Professor Ann Daly
Julian Leathart
Professor Alastair Burt
Professor Chris Day
Genetic variants regulating insulin receptor signalling are associated with the severity of liver damage in patients with non-alcoholic fatty liver disease2010
Ahmad Alserri
Professor Ann Daly
Professor Chris Day
Homozygosity for the Patatin-Like Phospholipase-3/Adiponutrin I148M Polymorphism Influences Liver Fibrosis in Patients with Nonalcoholic Fatty Liver Disease2010
Dr Peter Donaldson
Professor Ann Daly
Jill Henderson
Professor Chris Day
Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury2010
Professor Ann Daly
Professor Chris Day
Patatin-like phospholipase domain containing 3: A case in point linking genetic susceptibility for alcoholic and nonalcoholic liver disease2010
Joanna Stewart
Professor Rita Horvath
Professor Chris Day
Professor Patrick Chinnery
Polymerase γ Gene POLG Determines the Risk of Sodium Valproate-Induced Liver Toxicity2010
Dr James Frith
Professor Chris Day
Chris Elliott
Professor David Jones
Emerita Professor Julia Newton
et al.
Potential strategies to improve uptake of exercise interventions in non-alcoholic fatty liver disease2010
Professor Chris Day
Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease2010
Professor Stuart McPherson
Professor Alastair Burt
Professor Chris Day
Simple non-invasive fibrosis scoring systems can reliably exclude advanced fibrosis in patients with non-alcoholic fatty liver disease2010
Professor Chris Day
Standardization of nomenclature and causality assessment in drug-induced liver injury: Summary of a clinical research workshop2010
Professor Chris Day
Susceptibility to ALD: Where are we?2010
Professor David Jones
Professor Chris Day
The significance of autoantibodies in non-alcoholic fatty liver disease2010
Dr Stuart Kendrick
Elsbeth Henderson
Dr Jeremy Palmer
Professor David Jones
Professor Chris Day
et al.
Theophylline improves steroid sensitivity in acute alcoholic hepatitis2010
Professor Ann Daly
Dr Peter Donaldson
Dr Pallav Bhatnagar
Julia Patch
Professor Heather Cordell
et al.
HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin2009
Dr Nimantha De Alwis
Emeritus Professor Doug Turnbull
Professor Robert Taylor
Professor Laura Greaves
Professor Patrick Chinnery
et al.
A Methodological Approach to Tracing Cell Lineage in Human Epithelial Tissues2009
Dr Joseph Gray
Dr Dipanker Chattopadhyay
Dr Gary Beale
Dr Gillian Patman
Dr Luca Miele
et al.
A proteomic strategy to identify novel serum biomarkers for liver cirrhosis and hepatocellular cancer in individuals with fatty liver disease2009
Professor Chris Day
Abnormal serum alanine aminotransferase levels are associated with impaired insulin sensitivity in young women with polycystic ovary syndrome2009
Emerita Professor Julia Newton
Professor Chris Day
Authors' response2009
Professor Chris Day
Childhood NAFLD: A ticking timebomb?2009
Emerita Professor Julia Newton
Jessie Pairman
Katharine Wilton
Professor David Jones
Professor Chris Day
et al.
Fatigue and autonomic dysfunction in non-alcoholic fatty liver disease2009
Emerita Professor Julia Newton
Professor Chris Day
Fatigue in non-alcoholic fatty liver disease: is there a role for hypothyroidism Response2009
Professor Ann Daly
Professor Chris Day
Genetic Association Studies in Drug-Induced Liver Injury2009
Dr Nimantha De Alwis
Professor Gavin Hudson
Professor Alastair Burt
Professor Chris Day
Professor Patrick Chinnery
et al.
Human Liver Stem Cells Originate from the Canals of Hering2009
Dr Luca Miele
Professor Chris Day
Increased Intestinal Permeability and Tight Junction Alterations in Nonalcoholic Fatty Liver Disease2009
Dr James Frith
Professor Chris Day
Elsbeth Henderson
Professor Alastair Burt
Emerita Professor Julia Newton
et al.
Non-Alcoholic Fatty Liver Disease in Older People2009
Dr Gary Beale
Laura Pascoe
Dr Luca Miele
Professor Mark Walker
Professor Chris Day
et al.
The Kruppel-Like Factor 6 (KLF6) Genotype Which is Associated With NAFLD Progression is Associated with Higher Fasting Serum Glucose Levels in Healthy Individuals2009
Dr Stephen Stewart
Professor Chris Day
Dr Eilish Gilvarry
Adverse physical effects of alcohol misuse2008
Dr Gary Beale
Dr Dipanker Chattopadhyay
Dr Joseph Gray
Dr Stephen Stewart
Dr Mark Hudson
et al.
AFP, PIVKAII, GP3, SCCA-1 and follisatin as surveillance biomarkers for hepatocellular cancer in non-alcoholic and alcoholic fatty liver disease2008
Professor Chris Day
Antioxidants plus corticosteroids in the treatment of severe acute alcoholic hepatitis: The question is still open: Reply2008
Emerita Professor Julia Newton
Professor David Jones
Katharine Wilton
Professor Alastair Burt
Professor Chris Day
et al.
Fatigue in non-alcoholic fatty liver disease (NAFLD) is significant and associates with inactivity and excessive daytime sleepiness but not with liver disease severity or insulin resistance2008
Dr Nimantha De Alwis
Professor Chris Day
Genes and nonalcoholic fatty liver disease2008
Dr Pallav Bhatnagar
Professor Chris Day
Professor Ann Daly
Genetic variants of hepatic transporters and susceptibility to drug induced liver injury2008
Professor Chris Day
NASH predicts plasma inflammatory biomarkers independently of visceral fat in men2008
Professor Chris Day
No role of matrixmetalloproteinase-3 genetic promoter polymorphism 1171 as a risk factor for cirrhosis in alcoholic liver disease2008
Professor Chris Day
Non-alcoholic fatty liver disease is independently associated with an increased prevalence of chronic kidney disease and proliferative/laser-treated retinopathy in type 2 diabetic patients2008
Dr Nimantha De Alwis
Professor Chris Day
Non-alcoholic fatty liver disease: The mist gradually clears2008
Professor Chris Day
Non-alcoholic steatohepatitis: metabolic syndrome of the liver2008
Dr Dipanker Chattopadhyay
Professor Alastair Burt
Professor Chris Day
Noninvasive markers of fibrosis in nonalcoholic fatty liver disease: Validating the European Liver Fibrosis Panel and exploring simple markers2008
Elise Andrews
Professor Matthew Wright
Professor Chris Day
Professor Ann Daly
Relevance of PXR to Flucloxacillin-induced Liver Injury2008
Dr Luca Miele
Dr Gary Beale
Dr Gillian Patman
Julian Leathart
Professor Chris Day
et al.
The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease2008
Dr Nicholas Thompson
Professor Alastair Burt
Professor Chris Day
Professor Helen Reeves
Warfarin induced cholestatic jaundice in a patient receiving total parenteral nutrition2008
Dr Stuart Kendrick
Professor Chris Day
A coffee with your brandy, Sir?2007
Dr Martin Prince
Professor Margaret Bassendine
Dr Mark Hudson
Emeritus Professor Oliver James
Professor David Jones
et al.
A randomized trial of antioxidant therapy alone or with corticosteroids in acute alcoholic hepatitis2007
Professor Chris Day
Alcohol and the liver2007
Professor Chris Day
Benefits of lifestyle modification in NAFLD2007
Professor Chris Day
Differences and similarities in early atherosclerosis between patients with non-alcoholic steatohepatitis and chronic hepatitis B and C2007
Dr Gary Beale
Dr Luca Miele
Professor Helen Reeves
Professor Chris Day
Differential expression of GSTT1 and GSTT2 is associated with more advanced fibrosis in patients with NAFLD2007
Dr Graeme O'Boyle
Professor David Jones
Professor Chris Day
Effects of ethanol on endotoxin-mediated cytokine release: Sensitisation via TLR4 but normal tolerance2007
Dr Stuart Kendrick
Dr Graeme O'Boyle
Professor Jelena Mann
Professor David Jones
Professor Chris Day
et al.
Ethanol-induced histone acetylation: A novel mechanism for enhancement of inflammation in alcoholic hepatitis?2007
Professor Chris Day
European liver fibrosis (ELF) panel of serum markers can predict clinical outcome in a cohort of patients from England with mixed aetiology chronic liver disease2007
Emerita Professor Julia Newton
Professor David Jones
Elsbeth Henderson
Jessie Pairman
Katharine Wilton
et al.
Fatigue in NAFLD is severe and associates with excessive daytime somnolence but not with liver disease severity or insulin resistance2007
Dr Nimantha De Alwis
Professor Ann Daly
Julian Leathart
Dr Sushma Saksena
Professor Chris Day
et al.
Genetic evidence that lipid trafficking plays a key role in fibrosis in non alcoholic fatty liver disease2007
Professor Ann Daly
Julian Leathart
Richard Swainsbury
Professor Chris Day
Genetic Susceptibility to Diclofenac-Induced Hepatotoxicity: Contribution of UGT2B7, CYP2C8, and ABCC2 Genotypes2007
Dr Nimantha De Alwis
Professor Chris Day
Genetics of alcoholic liver disease and nonalcoholic fatty liver disease2007
Professor Chris Day
Long-term orlistat treatment reduces endotoxinaemia in fatty liver disease patients2007
Dr Stuart Kendrick
Dr Jeremy Palmer
Professor David Jones
Professor Chris Day
Lymphocyte steroid sensitivity in severe alcoholic hepatitis2007
Professor Chris Day
Management strategies in alcoholic liver disease2007
Dr Nimantha De Alwis
Dr Catherine Mowbray
Dr Angela Pyle
Julian Leathart
Professor Patrick Chinnery
et al.
Mitochondrial DNA haplogroups associated with histological severity in non-alcoholic fatty liver disease (NAFLD)2007
Professor Chris Day
Non-alcoholic fatty liver disease (NAFLD) and cardiovascular disease: An open question2007
Professor Chris Day
Nonsteroidal Anti-Inflammatory Drug-Induced Hepatotoxicity2007
Professor Chris Day
Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients2007
Professor Chris Day
Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients: Response to Schindhelm, Heine, and Diamant [3]2007
Professor Chris Day
Recent advances in clinical practice: Benefits of lifestyle modification in NAFLD2007
Professor Chris Day
The Glasgow alcoholic hepatitis score identifies patients who may benefit from corticosteroids2007
Dr Luca Miele
Dr Gary Beale
Julian Leathart
Professor Chris Day
Professor Helen Reeves
et al.
The KLF6 (IVS1-27G > a) polymorphism is associated with non-progressive NAFLD2007
Professor Ann Daly
Ahmad Alserri
Julian Leathart
Julia Patch
Professor Chris Day
et al.
The mitochondrial superoxide dismutase 2 (SOD2) targeting sequence polymorphism is associated with fibrotic NAFLD: Consistent evidence from case-control and intra-familial allelic association studies2007
Dr Sushma Saksena
Professor Alastair Burt
Professor Chris Day
The NAFLD fibrosis score: A noninvasive system that identifies liver fibrosis in patients with NAFLD2007
Professor Chris Day
Treatment of alcoholic liver disease2007
Professor Chris Day
A chat on fat in the liver2006
Alison Burt
Dr Simon Harris
Professor Chris Day
European liver fibrosis (ELF) markers accurately distinguish fibrosis severity in non alcoholic fatty liver disease (NAFLD); An external validation study2006
Professor Chris Day
From fat to inflammation2006
Professor Chris Day
Genes or environment to determine alcoholic liver disease and non-alcoholic fatty liver disease2006
Professor Chris Day
Genes or environment to determine ALD and NAFLD2006
Professor Chris Day
Julian Leathart
Professor Ann Daly
Genetic evidence for a role for gut flora in the pathogenesis of NASH in humans2006
Dr Nimantha De Alwis
Dr Catherine Mowbray
Professor Patrick Chinnery
Professor Chris Day
Mitochondrial DNA haplogrouping in non alcoholic fatty liver disease (NAFLD)2006
Professor Chris Day
Natural history of non alcoholic steatohepatitis (NASH) cirrhosis and stage 3 fibrosis2006
Professor Chris Day
Non-alcoholic fatty liver disease: current concepts and management strategies2006
Professor Chris Day
Non-alcoholic fatty liver disease: Current concepts and management strategies2006
Professor Chris Day
Non-alcoholic steatohepatitis: From cell biology to clinical practice2006
Dr Maria Lorite
Professor Alastair Burt
Professor Chris Day
Dr Michael Thompson
Phospholipase D and extracellular signal-regulated kinase in hepatic stellate cells: Effects of platelet-derived growth factor and extracellular nucleotides2006
Dr Kaushik Agarwal
Professor Chris Day
Polymorphisms in the T cell regulatory gene cytotoxic T lymphocyte antigen 4 influence the rate of acute rejection after liver transplantation2006
Professor Chris Day
Professor Helen Reeves
The genetic basis of hepatocellular cancer2006
Professor Chris Day
Analysis of factors predictive of mortality in alcoholic hepatitis and derivation and validation of the Glasgow alcoholic hepatitis score2005
Professor Chris Day
Chronic endotoxinemia in NAFLD: A potential role in the development of insulin resistance/diabetes and in liver disease progression?2005
Dr Kaushik Agarwal
Professor Chris Day
CTLA-4 gene polymorphisms are associated with acute rejection after liver transplantation2005
Professor Chris Day
Fatty liver disease is associated with both endotoxemia and sub-clinical inflammation prior to the onset of type 2 diabetes2005
Professor Chris Day
Patrick Hayes
Grading alcoholic hepatitis2005
Professor Chris Day
Grading alcoholic hepatitis [1] (multiple letters)2005
Dr Sushma Saksena
Professor Alastair Burt
Professor Chris Day
Immune response towards lipid peroxidation products as a predictor of progression of non-alcoholic fatty liver disease to advanced fibrosis2005
Professor Chris Day
Natural history of NAFLD: Remarkably benign in the absence of cirrhosis2005
Professor Chris Day
Emeritus Professor Steve Yeaman
Relationship between the inhibition of phosphatidic acid phosphohydrolase-1 by oleate and oleoyl-CoA ester and its apparent translocation2005
Professor Chris Day
[abstract] Selective breast tumor growth suppression mediated by the enhanced breast cancer-specific promoter2004
Professor Chris Day
A randomised controlled trial of calcineurin inhibitor (CNI) replacement with mycophenolate mofetil and steroids in liver transplant patients with renal dysfunction2004
Dr Stephen Stewart
Dr Beate Haugk
Professor Alastair Burt
Professor David Jones
Professor Chris Day
et al.
Anti-cytochrome P4502E1 autoantibody titre associates with immune liver histology in advanced alcoholic liver disease2004
Dr Stephen Stewart
Professor David Jones
Dr Beate Haugk
Professor Alastair Burt
Professor Chris Day
et al.
Correlation between anti-CYP2E1 titre and lymphocyte infiltration in ALD - An autoimmune disease in some patients?2004
Professor Chris Day
Professor Ann Daly
Genetic susceptibility to alcoholic liver disease2004
Professor Chris Day
Genetic susceptibility to alcoholic liver disease2004
Professor Ann Daly
Julian Leathart
Professor Chris Day
Hepatic Adducts, Circulating Antibodies, and Cytokine Polymorphisms in Patients with Diclofenac Hepatotoxicity2004
Professor Chris Day
Professor Volker Straub
Megalencephaly and perisylvian polymicrogyria with postaxial polydactyly and hydrocephalus: a rare brain malformation syndrome associated with mental retardation and seizures2004
Dr Stephen Stewart
Professor Chris Day
Professor David Jones
Oxidative Stress as a Trigger for Cellular Immune Responses in Patients with Alcoholic Liver Disease2004
Professor Chris Day
Role of oxidative stress in promoting immune reactions associated with alcoholic liver disease2004
Professor Chris Day
Steatosis and Hepatitis C Virus: Mechanisms and Significance for Hepatic and Extrahepatic Disease2004
Jacqui Morris
Dr Stephen Stewart
Professor Chris Day
The Glasgow Alcoholic Hepatitis Score identifies patients likely to benefit from corticosteroids2004
Jacqui Morris
Dr Stephen Stewart
Professor Chris Day
The Glasgow Alcoholic Hepatitis Score identifies patients likely to benefit from corticosteroids2004
Professor Chris Day
The potential role of genes in nonalcoholic fatty liver disease2004
Professor Chris Day
Upregulation of IKK alpha/IKK beta by integrin-linked kinase is required for HER2/neu-induced NF-kappa B antiapoptotic pathway2004
Professor Chris Day
Upregulation of IKK alpha/IKK beta by integrin-linked kinase is required for HER2/neu-induced NF-kappa B antiapoptotic pathway (vol 23, pg 3883, 2004)2004
Dr Stephen Stewart
Professor Chris Day
Validation of the Glasgow Alcoholic Hepatitis Score: Relevance to prognosis and corticosteroid response.2004
Professor Ann Daly
Julian Leathart
Professor Chris Day
A "loss-of-function" polymorphism in ICAM-1 protects heavy drinkers from alcoholic liver disease2003
Dr Anne Hicks
Professor Alastair Burt
Dr Michael Thompson
Professor Chris Day
Bile acids have a direct effect on collagen biosynthesis by hepatic stellate cells2003
Dr Matt Warren
Professor Chris Day
Chronic pancreatitis: A treatable, common, and underdiagnosed problem in patients with ALD2003
Professor Ann Daly
Julian Leathart
Dr Beate Haugk
Professor David Jones
Professor Alastair Burt
et al.
Evidence that alcoholic liver disease is due to immune mechanisms in genetically susceptible drinkers2003
Dr Stephen Stewart
Professor Ann Daly
Professor David Jones
Julian Leathart
Professor Chris Day
et al.
Genetic and epigenetic factors in autoimmune reactions toward cytochrome P4502E1 in alcoholic liver disease2003
Dr Sushma Saksena
Julian Leathart
Professor Alastair Burt
Emeritus Professor Oliver James
Professor Ann Daly
et al.
Genetic evidence supporting the two-hit model of NASH pathogenesis2003
Dr Sushma Saksena
Julian Leathart
Professor Ann Daly
Professor Chris Day
Manganese dependent superoxide dismutase (SOD2) targeting sequence polymorphism is associated with advanced fibrosis in patients with non-alcoholic fatty liver disease2003
Professor Chris Day
Professor David Jones
Neo-antigen specific T-cell responses are closely associated with the presence of liver disease in heavy drinkers2003
Dr Sushma Saksena
Professor Alastair Burt
Professor Chris Day
Oxidative stress is an independent risk factor for the progression of non-alcoholic fatty liver disease (NAFLD) to advanced fibrosis2003
Dr Martin Prince
Emeritus Professor Oliver James
Professor Chris Day
Dr Mark Hudson
Professor David Jones
et al.
Pain as a complication of opiate antagonist therapy in cholestasis: A single centre experience2003
Dr Martin Prince
Dr Mark Hudson
Professor Chris Day
Emeritus Professor Oliver James
Professor David Jones
et al.
Pain as a complication of use of opiate antagonists for symptom control in cholestasis2003
Julian Leathart
Professor Chris Day
Professor Ann Daly
Relationship of UGT2B7 genotype with diclofenac hepatotoxicity2003
Professor Chris Day
Emeritus Professor Oliver James
The effect of drinking behaviour on quality of life in patients with established alcoholic liver disease2003
Dr Stephen Stewart
Professor Chris Day
The management of alcoholic liver disease2003
Professor Chris Day
Who gets alcoholic liver disease: Nature or nurture? (extended abstract)2003
Julian Leathart
Professor Chris Day
Professor Ann Daly
Association of udp-glucuronosyltransferase (UGT) 2B7 genotype with diclofenac-induced hepatotoxicity2002
Dr Anne Hicks
Professor Alastair Burt
Dr Michael Thompson
Professor Chris Day
Bile acids have a direct effect on collagen biosynthesis by hepatic stellate cells2002
Professor Chris Day
CD14 promoter polymorphism associated with risk of NASH2002
Dr Matt Warren
Professor Chris Day
Chronic pancreatitis: A treatable, common and under-diagnosed problem in patients with aid2002
Professor Ann Daly
Professor Chris Day
CYP2C9 polymorphism and warfarin dose requirements2002
Professor Ann Daly
Julian Leathart
Dr Beate Haugk
Professor David Jones
Professor Alastair Burt
et al.
Evidence that alcoholic liver disease is due to immune mechanisms in genetically susceptible drinkers2002
Professor Chris Day
Dr Sushma Saksena
Julian Leathart
Professor Alastair Burt
Emeritus Professor Oliver James
et al.
Genetic evidence supporting the two-hit model of NASH pathogenesis2002
Professor Chris Day
Julian Leathart
Professor Ann Daly
Genetic evidence that fatty liver is involved in the pathogenesis of advanced alcoholic liver disease2002
Professor Chris Day
Lipid peroxidation contributes to immune reactions associated with alcoholic liver disease2002
Professor Chris Day
NASH-Related liver failure: One hit too many?2002
Professor Chris Day
Professor David Jones
Neo-antigen specific T-cell responses are closely associated with the presence of liver disease in heavy drinkers2002
Professor Chris Day
Non-alcoholic steatohepatitis (NASH): where are we now and where are we going?2002
Professor Chris Day
Non-alcoholic steatohepatitis (NASH): why biopsy? - Author's reply2002
Professor Chris Day
Dr Sushma Saksena
Non-alcoholic steatohepatitis: Definitions and pathogenesis2002
Dr Martin Prince
Emeritus Professor Oliver James
Professor Chris Day
Dr Mark Hudson
Professor David Jones
et al.
Pain as a complication of opiate antagonist therapy in cholestasis: A single centre experience2002
Professor Chris Day
Pathogenesis of steatohepatitis2002
Professor Ann Daly
Professor Chris Day
Dr Peter Donaldson
Polymorphisms in immunoregulatory genes: towards individualised immunosupressive therapy?2002
Dr Peter Donaldson
Professor Chris Day
Predictive Value of Cytokine Polymorphisms for Liver Disease2002
Professor Chris Day
Dr Richard Virden
Emeritus Professor Steve Yeaman
Regulation of phosphatidic acid phosphohydrolase 1 by fatty acids2002
Professor Chris Day
The suppression of colon cancer cell growth in nude mice by targeting beta-catenin/TCF pathway2002
Professor Chris Day
Transplantation for alcoholic liver disease2002
Dr Stephen Stewart
Julian Leathart
Professor Ann Daly
Professor Chris Day
Valine-alanine manganese superoxide dismutase polymorphism is not associated with alcohol-induced oxidative stress or liver fibrosis2002
Dr Stephen Stewart
Professor Ann Daly
Julian Leathart
Professor David Jones
Professor Chris Day
et al.
A polymorphism in CTLA-4 is associated with the presence of anti-CYP2E1 antibody titres in patients with alcoholic liver disease2001
Dr Stephen Stewart
Professor David Jones
Professor Chris Day
Alcoholic liver disease: New insights into mechanisms and preventative strategies2001
Professor Chris Day
Apoptosis and acute alcoholic hepatitis: a novel therapeutic target?2001
Professor Chris Day
Apoptosis in alcoholic hepatitis: A novel therapeutic target?2001
Professor Chris Day
Julian Leathart
Professor Ann Daly
Dr Mark Hudson
Association of a 5'-flanking region polymorphism in the interleukin-4 gene with Crohn’s disease in a British population.2001
Professor Chris Day
Julian Leathart
Professor Ann Daly
Dr Mark Hudson
Association of single nucleotide polymorphisms in the interleukin-4 gene and interleukin-4 receptor gene with Crohn's disease in a British population2001
Professor Chris Day
Association of the tumour necrosis factor  -308 but not the interleukin 10 -627 promoter polymorphism with genetic susceptibility to primary sclerosing cholangitis2001
Professor Ann Daly
Professor Chris Day
Candidate gene case-control association studies: advantages and potential pitfalls2001
Professor Chris Day
Heavy drinking greatly increases the risk of cirrhosis in patients with HCV hepatitis2001
Dr Maria Lorite
Professor Alastair Burt
Professor Chris Day
Professor Albert Geerts
Identification of phospholipase D gene products in activated rat hepatic stellate cells - Stimulation by PDGF and nucleotides2001
Professor Helen Reeves
Professor Alastair Burt
Professor Chris Day
Integrin receptor expression changes in diseased hepatic stellate cells2001
Dr Stephen Stewart
Professor Chris Day
Liver disorder and the HFE locus2001
Dr Stephen Stewart
Dr Mark Hudson
David Talbot
Professor Derek Manas
Professor Chris Day
et al.
Mycophenolate mofetil monotherapy in liver transplantation2001
Dr Kaushik Agarwal
Professor Ann Daly
Julian Leathart
Dr Mark Hudson
Professor Chris Day
et al.
Polymorphisms of immunoregulatory genes: A step towards individually tailored immunosuppression?2001
Professor Chris Day
Prevalence of auto-antibodies against cytochrome in alcoholic liver disease2001
Dr Maria Lorite
Professor Debra Bevitt
Professor Chris Day
Regulation of ADAMS family members in hepatic stellate cells by soluble growth factors: Evidence for their role in hepatic fibrogenesis2001
Dr Alison Sutherland
Professor Chris Day
Dr Mark Welfare
Professor Ann Daly
Dr John Mansfield
et al.
Role of polymorphisms in the interleukin-10 gene in determining disease susceptibility and phenotype in inflamatory bowel disease2001
Dr Maria Lorite
Professor Debra Bevitt
Professor Chris Day
The ADAMs: A modular protein family with metalloproteinase and proteoglycan degrading activities expressed by the hepatic stellate cell2001
Professor Chris Day
Professor Ann Daly
The genetic basis for non-alcoholic and alcoholic steatohepatitis.2001
Professor Chris Day
Clinical diagnostic scale: A useful tool in the evaluation of suspected hepatotoxic adverse drug reactions2000
Professor Ann Daly
Professor Margaret Bassendine
Professor Chris Day
Interleukin 10 promoter region polymorphisms and susceptibility to advanced alcoholic liver disease2000
Professor Chris Day
Julian Leathart
Professor Ann Daly
Relationship of polymorphism in CYP2C9 to genetic susceptibility to diclofenac-induced hepatitis2000
Professor Chris Day
Who gets alcoholic liver disease: Nature or nurture?2000
Emeritus Professor Chris Seal
Professor Chris Day
Alcoholism: Effects on Nutritional Status1999
Professor Chris Day
Dr Patrick Kesteven
Professor Ann Daly
Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications1999
Professor Chris Day
HFE and alcoholic liver disease - Reply1999
Professor Loranne Agius
Emeritus Professor Steve Yeaman
Professor Chris Day
Inhibition of rat hepatocyte proliferation by transforming growth factor beta and glucagon is associated with inhibition of ERK2 and p70 S6 kinase1999
Emeritus Professor Oliver James
Professor Chris Day
Non-alcoholic steatohepatitis [Reply]1999
Emeritus Professor Oliver James
Professor Chris Day
Non-alcoholic steatohepatitis: Another disease of affluence1999
Professor Chris Day
The natural history of histologically proved drug induced liver disease1999
Professor David Jones
Emerita Professor Julia Newton
Professor Ann Daly
Professor Chris Day
Emeritus Professor Oliver James
et al.
Tumour necrosis factor-α promoter polymorphisms in primary biliary cirrhosis1999
Professor Chris Day
Dr Patrick Kesteven
Professor Ann Daly
Warfarin dose requirement and CYP2C9 polymorphisms - Reply1999
Professor Ann Daly
Professor Margaret Bassendine
Emeritus Professor Oliver James
Professor Chris Day
The RsaI polymorphism of CYP2E1 and susceptibility to alcoholic liver disease in Caucasians: Effect on age of presentation and dependence on alcohol dehydrogenase genotype1998