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Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1′-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism

Lookup NU author(s): Dr Phillip Probert, Dr Jeremy Palmer, Dr Aimen Amer, Steven White, Professor David Jones, Professor Matthew Wright



This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Publication metadata

Author(s): Probert PM, Palmer JM, Alhusainy W, Amer AO, Rietjens IMCM, White SA, Jones DE, Wright MC

Publication type: Article

Publication status: Published

Journal: Toxicology Letters

Year: 2016

Volume: 243

Pages: 98-110

Print publication date: 22/01/2016

Online publication date: 29/12/2015

Acceptance date: 23/12/2015

Date deposited: 29/01/2016

ISSN (print): 0378-4274

ISSN (electronic): 1879-3169

Publisher: Elsevier Ireland Ltd


DOI: 10.1016/j.toxlet.2015.12.010

PubMed id: 26739637


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Funder referenceFunder name
Alternatives Research and Development Foundation
Libyan Ministry of Higher Education and Scientific Research
287596European Commission FP7 program grant 'd-LIVER' (EC Contract)
NC/K500471/1National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs)