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Pyrrolcarboxamide Derivatives for the Inhibition of ERK5

Lookup NU author(s): Tristan Reuillon, Duncan MillerORCiD, Stephanie Myers, Dr Lauren Molyneux, Dr Celine CanoORCiD, Dr Ian HardcastleORCiD, Professor Roger Griffin, Dr Laurent Rigoreau, Emeritus Professor Bernard Golding, Professor Martin NobleORCiD


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The invention provides compounds of formula (I) or a tautomer, stereoisomer, N-oxide, pharmaceutically acceptable salt or solvate thereof. The compounds are useful for the prophylaxis or treatment of a disease state or condition mediated by ERK5, in particular cancers

Publication metadata

Inventor(s): Reuillon T, Miller D, Myers S, Molyneux L, Cano C, Hardcastle I, Griffin R, Rigoreau L, Golding B, Noble M

Publication type: Patent

Publication status: Published

Year: 2016

Print publication date: 24/03/2016

Acceptance date: 24/03/2016