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Browsing publications by Professor Martin Noble

Newcastle AuthorsTitleYearFull text
Pasquale Morese
Ayaz Ahmad
Dr Mathew Martin
Dr Richard Noble
Sara Pintar
et al.
Correction to: Factors affecting irreversible inhibition of EGFR and influence of chirality on covalent binding (Communications Chemistry, (2025), 8, 1, (111), 10.1038/s42004-025-01501-6)2025
Dr Ian Hope
Dr Mathew Martin
Dr Ziwei Jiang
Professor Mike Waring
Professor Martin Noble
et al.
Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction2025
Dr Jessica Watt
Dr Mathew Martin
Professor Jane Endicott
Professor Martin Noble
Different applications and differentiated libraries for crystallographic fragment screening2025
Pasquale Morese
Ayaz Ahmad
Dr Mathew Martin
Dr Richard Noble
Sara Pintar
et al.
Factors affecting irreversible inhibition of EGFR and influence of chirality on covalent binding2025
Dr Owen Burbidge
Dr Martyna Pastok
Dr Diana Papini
Kenneth Tan
Dr Shannon Turberville
et al.
Nanobodies restore stability to cancer-associated mutants of tumor suppressor protein p16INK4a2025
Rhianna Rowland
Svitlana Korolchuk
Dr Marco Salamina
Dr Natalie Tatum
Professor Martin Noble
et al.
Cryo-EM structure of the CDK2-cyclin A-CDC25A complex2024
Dr Celine Cano
Professor Jane Endicott
Dr Ian Hardcastle
Dr Claire Jennings
Suzanne Kyle
et al.
Discovery of ASTX295, a potent, next-generation small molecule antagonist of MDM2 with differentiated pharmacokinetic profile2024
Dr Martyna Pastok
Dr Shannon Turberville
Dr Arnaud Basle
Professor Martin Noble
Professor Jane Endicott
et al.
Structural requirements for the specific binding of CRABP2 to cyclin D32024
Dr Elaine Willmore
Suzanne Kyle
Dr Yan Zhao
Huw Thomas
Dr Kenneth Rankin
et al.
Targeting the MDM2-p53 interaction: Time- and concentration-dependent studies in tumor and normal human bone marrow cells reveal strategies for an enhanced therapeutic index2024
Rhianna Rowland
Dr Richard Heath
Professor Jane Endicott
Professor Martin Noble
Dr Marco Salamina
Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP12023
Dr Mathew Martin
Professor Jane Endicott
Professor Martin Noble
Dr Natalie Tatum
Crystallographic fragment screening in academic cancer drug discovery2023
Dr Catherine Salvini
Benoit Darlot
Jack Davison
Dr Mathew Martin
Dr Susan Tudhope
et al.
Fragment expansion with NUDELs – poised DNA-encoded libraries2023
Dr Nahoum Anthony
Charlotte Jennings
Dr Mathew Martin
Dr Richard Noble
Nicole Phillips
et al.
Targeting cytotoxic agents through EGFR-mediated covalent binding and release2023
Dr Arnaud Basle
Professor Martin Noble
The CCP4 suite: integrative software for macromolecular crystallography2023
Melanie Uguen
Gemma Davison
James Hunter
Dr Mathew Martin
Dr Shannon Turberville
et al.
Build–Couple–Transform: A paradigm for lead-like library synthesis with scaffold diversity2022
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