Browse by author
Lookup NU author(s): Jordan Warner, Dr Rachel Stocker, Dr Kirsten BrandtORCiD, Professor Emma Stevenson, Dr Adrian Holliday
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
© 2024Glycomacropeptide (GMP) has a unique amino acid profile which may make less satiating than other dietary proteins. This study assessed the feasibility and likely acceptability of a leucine-enriched GMP drink and determined appetite response in older adults (OA). Thirteen OA (11f; 70 ± 4 years) were recruited for sensory assessments of a leucine-enriched GMP drink when mixed with water and with fruit smoothie, compared with whey protein isolate (WHEY). Participants also partook in a single focus group exploring acceptability to protein and supplementation. Separately, a counterbalanced, double-blind study with twelve OA (8f; 69 ± 3 years) was conducted to determine appetite and gut hormone responses. Fasting subjective appetite was recorded using visual analogue scales and a fasted venous blood sample was collected (to measures acyl-ghrelin, PYY, GLP-1, and CCK) before participants consumed either: GMP protein (27g + 3g leucine, 350 mL water), WHEY (30g, 350 mL water), or water. Participants rested for 240 min, with appetite measures and blood sampling throughout. An ad libitum pasta-based meal was then consumed. Sensory testing revealed low pleasantness rating for GMP in water vs. WHEY (16 ± 14 vs 31 ± 24, p = 0.016). GMP addition to smoothie reduced pleasantness (26 ± 21 vs. 61 ± 29, p = 0.009) and worsened the aroma (46 ± 15 vs. 69 ± 28, p = 0.014). The focus group revealed uncertainty of protein needs and a scepticism of supplements, with preference for food. Gut hormone response did not differ between GMP and WHEY (nAUC for all gut hormones p > 0.05). There was no difference between conditions for lunch ad libitum intake (549 ± 171 kcal, 512 ± 238 kcal, 460 ± 199 kcal for GMP, WHEY, and water, p = 0.175), or for subjective appetite response. Leucine-enriched GMP was not less satiating than WHEY, and low palatability and scepticism of supplements question the likely acceptability of GMP supplementation. Providing trusted nutritional advice and food enrichment/fortification may be preferred strategies for increasing protein intake in OA.
Author(s): Warner J, Stocker R, Brandt K, Crabtree DR, Ormond L, Stevenson E, Holliday A
Publication type: Article
Publication status: Published
Journal: Appetite
Year: 2024
Volume: 200
Print publication date: 01/09/2024
Online publication date: 23/05/2024
Acceptance date: 21/05/2024
ISSN (print): 0195-6663
ISSN (electronic): 1095-8304
Publisher: Academic Press
URL: https://doi.org/10.1016/j.appet.2024.107509
DOI: 10.1016/j.appet.2024.107509
PubMed id: 38795943
Altmetrics provided by Altmetric
