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Skeletal muscle effects of Janus kinase inhibition in rheumatoid arthritis (RAMUS): a single arm, experimental medicine study

Lookup NU author(s): Dr Josh Bennett, Dr Kieren HollingsworthORCiD, Dr Arthur PrattORCiD, Abbie Degnan, Professor Grainne Gorman, Catherine Feeney, Najib NaamaneORCiD, Dr Jérémie NsengimanaORCiD, Professor Avan SayerORCiD, Dr Amy AndersonORCiD, Professor John IsaacsORCiD

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Author(s): Bennett JL, Hollingsworth KG, Pratt AG, Degnan AEA, Gorman GS, Feeney C, Naamane N, Nsengimana J, Sayer AA, Anderson AE, Isaacs JD

Publication type: Article

Publication status: Published

Journal: Lancet Rheumatology

Year: 2025

Pages: epub ahead of print

Online publication date: 15/10/2025

Acceptance date: 11/08/2025

Date deposited: 28/11/2025

ISSN (electronic): 2665-9913

Publisher: The Lancet Publishing Group

URL: https://doi.org/10.1016/S2665-9913(25)00184-5

DOI: 10.1016/S2665-9913(25)00184-5

Data Access Statement: De-identified individual participant data from the RAMUS study will be available from 12 months after publication. Reasonable requests for data can be submitted to the corresponding author and will be considered on an individual basis. Researchers will need to submit a proposal outlining the intended use of the data and sign a data access agreement. Additional study documents including the study protocol, statistical analysis plan, informed consent form, and analytic code will also be available.

PubMed id: 41109315

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