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Glycation of alpha-synuclein enhances aggregation and neuroinflammatory responses

Lookup NU author(s): Searlait Thom, Dr Daniel ErskineORCiD, Professor Tiago OuteiroORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Publication metadata

Author(s): Vasili E, Konig C, Al-Azzani M, Bosbach C, Gaztemeier LM, Thom S, Chegao A, Miranda HV, Steinem C, Erskine D, Outeiro TF

Publication type: Article

Publication status: Published

Journal: npj Parkinson's disease

Year: 2025

Volume: 11

Online publication date: 23/10/2025

Acceptance date: 16/09/2025

Date deposited: 23/10/2025

ISSN (electronic): 2373-8057

Publisher: Nature Publishing Group

URL: https://doi.org/10.1038/s41531-025-01159-w

DOI: 10.1038/s41531-025-01159-w

Data Access Statement: The data obtained in this research are available from the corresponding author upon reasonable request.


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Funding

Funder referenceFunder name
D.E. is funded by an Alzheimer’s Research UK Senior Fellowship (ARUK-SRF2022A-006)
Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany's Excellence Strategy, EXC 2067/1-390729940
EU Joint Program – Neurodegenerative Disease Research project OligoFIT
Michael J Fox Foundation
Open Access funding enabled and organized by Projekt DEAL.
SFB 1286 (project B8)

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