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Browsing publications by Dr Daniel Erskine.

Newcastle AuthorsTitleYearFull text
Dr Calum Hamilton
Professor Fiona Matthews
Professor Johannes Attems
Dr Paul Donaghy
Dr Daniel Erskine
et al.
Associations between multimorbidity and neuropathology in dementia: Consideration of functional cognitive disorders, psychiatric illness and dementia mimics2024
Dr Tetsushi Kataura
Lucy Sedlackova
Niall Wilson
Dr Satomi Miwa
Dr Daniel Erskine
et al.
Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models2024
Dr Laura Alexandra Smith
Dr Chun Chen
Dr Nichola Lax
Professor Robert Taylor
Dr Daniel Erskine
et al.
Astrocytic pathology in Alpers’ syndrome2023
Dr Elizaveta Olkhova
Dr Laura Alexandra Smith
Carla Bradshaw
Professor Grainne Gorman
Dr Daniel Erskine
et al.
Neurological Phenotypes in Mouse Models of Mitochondrial Disease and Relevance to Human Neuropathology2023
Dr Chun Chen
Dr David McDonald
Dr Alasdair Blain
Emily Mossman
Kiera Atkin
et al.
Parkinson’s disease neurons exhibit alterations in mitochondrial quality control proteins2023
Dr Chun Chen
Emily Mossman
Dr David McDonald
Dr Alasdair Blain
Laura Bone
et al.
Astrocytic Changes in Mitochondrial Oxidative Phosphorylation Protein Levels in Parkinson's Disease2022
Dr Paul Donaghy
Dr Simon Cockell
Dr Carmen Martin-Ruiz
Dr Jonathan Coxhead
Dr Joseph Kane
et al.
Blood mRNA expression in Alzheimer’s disease and dementia with Lewy bodies2022
Dr Laura Alexandra Smith
Dr Daniel Erskine
Dr Alasdair Blain
Professor Robert Taylor
Professor Bobby McFarland
et al.
Delineating selective vulnerability of inhibitory interneurons Alpers' syndrome.2022
Dr Daniel Erskine
Disease-Associated α-Synuclein Aggregates as Biomarkers of Parkinson Disease Clinical Stage2022
Dr Yi Ng
Dr Nichola Lax
Dr Alasdair Blain
Dr Daniel Erskine
Professor Mark Baker
et al.
Forecasting stroke-like episodes and outcomes in mitochondrial disease2022
Dr Daniel Erskine
Dr Paul Donaghy
Professor Ian McKeith
Professor John O'Brien
Professor Alan Thomas
et al.
Inflammation in dementia with Lewy bodies2022
Dr Daniel Erskine
Novel engineered nanobodies specific for N-terminal region of alpha-synuclein recognize Lewy-body pathology and inhibit in-vitro seeded aggregation and toxicity2022
Dr David Koss
Dr Daniel Erskine
Dr Andrew Porter
Dr Pawel Palmowski
Professor Johannes Attems
et al.
Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies.2022
Chris Hatton
Dr David Koss
Dr Lauren Walker
Professor Tiago Outeiro
Professor Johannes Attems
et al.
Prion-like α-synuclein pathology in the brain of infants with Krabbe disease2022
Dr Daniel Erskine
Professor Johannes Attems
Professor Ian McKeith
Professor Tiago Outeiro
α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity2022
Dr Clare Tweedy
Nathan Kindred
Professor John-Paul Taylor
Dr Daniel Erskine
Dr Christopher Morris
et al.
Hippocampal network hyperexcitability in young transgenic mice expressing human mutant alpha-synuclein2021
Dr Daniel Erskine
Professor Johannes Attems
Insights into Lewy body disease from rare neurometabolic disorders2021
Dr Daniel Erskine
Dr David Koss
Professor Viktor Korolchuk
Professor Tiago Outeiro
Professor Johannes Attems
et al.
Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders2021
Dr Calum Hamilton
Professor Fiona Matthews
Dr Daniel Erskine
Professor Johannes Attems
Professor Alan Thomas
et al.
Neurodegenerative brain changes are associated with area deprivation in the United Kingdom: findings from the Brains for Dementia Research study2021
Dr Daniel Erskine
Dr Christopher Morris
RT-QuIC using C-terminally truncated a-synuclein forms detects differences in seeding propensity of different brain regions from synucleinopathies2021
Chris Hatton
Dr Amy Reeve
Dr Nichola Lax
Dr Alasdair Blain
Dr Yi Ng
et al.
Complex I reductions in the nucleus basalis of Meynert in Lewy body dementia: the role of Lewy bodies2020
Dr Kirsty McAleese
Dr Lauren Walker
Dr Daniel Erskine
Mary Johnson
Dr David Koss
et al.
Concomitant LATE-NC in Alzheimer's disease is not associated with increased tau or amyloid-β pathological burden2020
Dr Daniel Erskine
Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity2020
Dr Daniel Erskine
Generation of monoclonal antibodies against phosphorylated α-Synuclein at serine 129: Research tools for synucleinopathies2020
Dr Daniel Erskine
Dr Christopher Morris
Professor Johannes Attems
Investigating the Presence of Doubly‐phosphorylated α‐Synuclein at Tyrosine 125 and Serine 129 In Idiopathic Lewy Body Diseases2020
Dr Daniel Erskine
Dr Amy Reeve
Dr Tuomo Polvikoski
Dr Andrew Schaefer
Professor Robert Taylor
et al.
Lewy body pathology is more prevalent in older individuals with mitochondrial disease than controls2020
Dr Daniel Erskine
Antibodies against alpha‐synuclein: tools and therapies2019
Dr Daniel Erskine
Professor John-Paul Taylor
Cholinergic muscarinic M1 and M4 receptors as therapeutic targets for cognitive, behavioural, and psychological symptoms in psychiatric and neurological disorders2019
Professor Tiago Outeiro
Dr David Koss
Dr Daniel Erskine
Dr Lauren Walker
Abishek Umashankar
et al.
Dementia with Lewy bodies: an update and outlook2019
Dr Kirsty McAleese
Madhurima Dey
Dr Lauren Walker
Dr Daniel Erskine
Mary Johnson
et al.
Extravascular fibrinogen in the white matter of Alzheimer’s disease and normal aged brains: implications for fibrinogen as a biomarker for Alzheimer’s disease2019
Dr Daniel Erskine
Dr Christopher Morris
Heterogeneity in α-synuclein sub-types and their expression in cortical brain tissue lysates from Lewy body diseases and Alzheimer's disease2019
Dr Lauren Walker
Dr Kirsty McAleese
Dr Daniel Erskine
Professor Johannes Attems
Neurodegenerative Diseases and Ageing2019
Dr Daniel Erskine
Parkinson's disease biomarkers based on alpha-synuclein2019
Dr Daniel Erskine
Professor John-Paul Taylor
Professor Alan Thomas
Daniel Collerton
Professor Ian McKeith
et al.
Pathological Changes to the Subcortical Visual System and its Relationship to Visual Hallucinations in Dementia with Lewy Bodies2019
Dr Daniel Erskine
Professor Alan Thomas
Dr Ahmad Khundakar
Dr Peter Hanson
Professor John-Paul Taylor
et al.
Molecular changes in the absence of severe pathology in the pulvinar in dementia with Lewy bodies2018
Dr Daniel Erskine
Lina Patterson
Dr Athanasios Alexandris
Dr Peter Hanson
Professor Ian McKeith
et al.
Regional levels of physiological α-synuclein are directly associated with Lewy body pathology2018
Dr Daniel Erskine
Professor Alan Thomas
Professor John-Paul Taylor
Michael Savage
Professor Johannes Attems
et al.
Neuronal Loss and Α-Synuclein Pathology in the Superior Colliculus and Its Relationship to Visual Hallucinations in Dementia with Lewy Bodies2017
Dr Kirsty McAleese
Dr Lauren Walker
Mary Johnson
Dr Daniel Erskine
Dr Sean Colloby
et al.
Parietal white matter lesions in Alzheimer's disease are associated with cortical neurodegenerative pathology, but not with small vessel disease2017
Dr Lauren Walker
Dr Kirsty McAleese
Mary Johnson
Dr Ahmad Khundakar
Dr Daniel Erskine
et al.
Quantitative neuropathology: an update on automated methodologies and implicationsfor large scale cohorts2017
Dr Daniel Erskine
Professor Alan Thomas
Professor Johannes Attems
Professor John-Paul Taylor
Professor Ian McKeith
et al.
Specific patterns of neuronal loss in the pulvinar nucleus in dementia with Lewy bodies2017
Dr Kirsty McAleese
Dr Lauren Walker
Dr Daniel Erskine
Professor Alan Thomas
Professor Ian McKeith
et al.
TDP-43 pathology in Alzheimer's disease, dementia with Lewy bodies and ageing2017
Dr Ahmad Khundakar
Dr Peter Hanson
Dr Daniel Erskine
Dr Nichola Lax
Evangelia Karyka
et al.
Analysis of primary visual cortex in dementia with Lewy bodies indicates GABAergic involvement associated with recurrent complex visual hallucinations2016
Dr Daniel Erskine
Dr Ahmad Khundakar
Stereological approaches to dementia research using human brain tissue2016
Dr Kirsty McAleese
Dr Lauren Walker
Dr Daniel Erskine
Professor Johannes Attems
The prevalence of TDP-43 pathology in Alzheimer's disease, Lewy body dementia and mixed Alzheimer's disease and Lewy body disease2016
Dr Daniel Erskine
Professor John-Paul Taylor
Dr Michael Firbank
Professor John O'Brien
Professor Ian McKeith
et al.
Changes to the lateral geniculate nucleus in Alzheimer's disease but not dementia with Lewy bodies2015