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Lookup NU author(s): Dr Stephen Stewart,
Professor David Jones,
Professor Chris Day
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
Alcoholic liver disease has a known aetiology but a complex pathogenesis. It is an extremely common disease with a high mortality, but the reason why only a relatively small proportion of heavy drinkers progress to advanced disease remains elusive. Accumulating evidence points towards an elaborate interplay between metabolism, inflammation and immunity in the development of steatosis, hepatitis and fibrosis. These complex pathways leading to liver injury offer many potential susceptibility loci, as well as sites for potential therapeutic intervention.
Author(s): Stewart S, Jones D, Day CP
Publication type: Review
Publication status: Published
Journal: Trends in Molecular Medicine
ISSN (print): 1471-4914
ISSN (electronic): 1471-499X
PubMed id: 11530336