Browse by author
Lookup NU author(s): Professor Anne Dickinson, Dr Jennifer Cavet, Dr Hannah Cullup, Dr Xiao WangORCiD, Dr Mark Jarvis, Dr Peter Middleton
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
This review summarizes recent results investigating the role of certain cytokine gene polymorphisms, including those of TNF-α, IFN-γ, IL-6, IL-10 and IL-1 receptor antagonist (IL-1Ra), in allogeneic stem cell transplantation. It discusses their role in predicting outcome and the development of a genetic risk index for graft versus host disease (GvHD) in HLA-matched sibling transplants. By the comparative use of an in vitro human skin explant model, initial results suggest that certain cytokine gene polymorphisms may be associated with more severe disease.
Author(s): Dickinson AM, Cavet J, Cullup H, Wang XN, Jarvis M, Sviland L, Middleton PG
Publication type: Review
Publication status: Published
Journal: Archivum Immunologiae et Therapiae Experimentalis
Year: 2002
Volume: 50
Issue: 6
Pages: 371-378
Print publication date: 01/01/2002
ISSN (print): 0004-069X
ISSN (electronic): 1661-4917
PubMed id: 12546063
