Ahmed Aljohani
Yucheng Lu
Dr Kelly Jackson
Dr Paul Waddell
Dr Jason Gill
et al. | Benzoxa-[2,1,3]-diazole substituted amino acid hydrazides as therapeutics for drug-resistant Mycobacterium tuberculosis | 2025 |
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Yucheng Lu
Daniel Partleton
Musa Gugu
Ahmed Alhejaili
Dr Jonathan Harburn
et al. | Structural isomerisation affects the antitubercular activity of adamantyl-isoxyl adducts | 2025 |
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Natalie Roper
Aaron Campbell
Dr Paul Waddell
Dr Alistair Brown
Dr Roly Armstrong
et al. | A stereodivergent multicomponent approach for the synthesis of C–N atropisomeric peptide analogues | 2024 |
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Dr Alistair Brown
| Cryo-electron microscopy structure of the di-domain core of Mycobacterium tuberculosis polyketide synthase 13, essential for mycobacterial mycolic acid synthesis | 2024 |
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Dr Alistair Brown
Alaa Aljohani
Fatimah Alsalem
Dr Jason Gill
Dr Jon Sellars
et al. | Identification of Substituted Amino Acid Hydrazides as Novel Anti-Tubercular Agents, Using a Scaffold Hopping Approach | 2020 |
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Dr Alistair Brown
| Crystal structure of Mycobacterium tuberculosis FadB2 implicated in mycobacterial b-oxidation | 2019 |
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Dr Alistair Brown
Ahmed Aljohani
Dr Jason Gill
Dr Jon Sellars
| Identification of novel benzoxa-[2,1,3]-diazole substituted amino acid hydrazides as potential anti-tubercular agents | 2019 |
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Dr Simon Bridge
Dr Alistair Brown
Dr Darren Smith
| Shigatoxin encoding Bacteriophage ɸ24β modulates bacterial metabolism to raise antimicrobial tolerance | 2017 |
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Dr Alistair Brown
Dr Darren Smith
| Synthesis and SAR evaluation of novel thioridazine derivatives active against drug-resistant tuberculosis | 2017 |
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Dr Alistair Brown
| Design and Synthesis of 1-((1,5-Bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl)methyl)-4-methylpiperazine (BM212) and N-Adamantan-2-yl-N′-((E)-3,7-dimethylocta-2,6-dienyl)ethane-1,2-diamine (SQ109) Pyrrole Hybrid Derivatives: Discovery of Potent Antitubercular Agents Effective against Multidrug-Resistant Mycobacteria | 2016 |
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Kristoffer Winther
Dr Alistair Brown
Professor Kenn Gerdes
| VapC20 of Mycobacterium tuberculosis Cleaves the Sarcin Ricin Loop of 23S rRNA | 2013 |
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Dr Alistair Brown
| Probing the mechanism of the Mycobacterium tuberculosis β-ketoacyl-acyl carrier protein synthase III mtFabH: Factors influencing catalysis and substrate specificity | 2005 |
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Dr Laurent Kremer
Dr Lynn Dover
Dr Severine Carrere
Dr Madhavan Nampoothiri
Dr Alistair Brown
et al. | Mycolic acid biosynthesis and enzymic characterization of the beta-ketoacyl-ACP synthase A-condensing enzyme from Mycobacterium tuberculosis | 2002 |
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