Shangze Xu
Lanyu Fan
Dr Piotr Zaborniak
Dr Ruidi Zhu
Haoyuan Ji
et al. | "Druggability" of the PAS domains of human PASK kinase, a therapeutic target for metabolic and liver disorders | 2025 |
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Dr Kate Harris
Dr Manuela Jorg
| Recommended Tool Compounds: Thienotriazolodiazepines-derivatized Chemical Probes to Target BET Bromodomains | 2025 |
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Dr Kate Harris
| Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia | 2024 |
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Dr Kate Harris
| A pharmacophore-based approach to demonstrating the scope of alcohol dehydrogenases | 2023 |
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Shangze Xu
Matthew Kondal
Dr Ayaz Ayaz
Dr Ruidi Zhu
Lanyu Fan
et al. | Mechanistic Investigation of the Androgen Receptor DNA-Binding Domain and Modulation via Direct Interactions with DNA Abasic Sites: Understanding the Mechanisms Involved in Castration-Resistant Prostate Cancer | 2023 |
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Dr Kate Harris
| Phenotypic screening identifies a trisubstituted imidazo[1,2-a]pyridine series that induces differentiation in multiple AML cell lines | 2023 |
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Amelia Stennett
Kallie Friston
Professor Claire Harris
Dr Adam Wollman
Dr Agnieszka Bronowska
et al. | The case for complement component 5 as a target in neurodegenerative disease | 2023 |
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Dr Kate Harris
| A tubulin binding molecule drives differentiation of acute myeloid leukemia cells | 2022 |
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Dr Kate Harris
| Pilot Study to Quantify Palladium Impurities in Lead-like Compounds Following Commonly Used Purification Techniques | 2022 |
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Dr Kate Harris
| A Phenotypic Screen Identifies a Compound Series That Induces Differentiation of Acute Myeloid Leukemia Cells In Vitro and Shows Antitumor Effects In Vivo | 2021 |
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Dr Manuela Jorg
Dr Kate Harris
| The right tools for the job: the central role for next generation chemical probes and chemistry-based target deconvolution methods in phenotypic drug discovery | 2021 |
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Dr Kate Harris
| A low temperature, vinylboronate ester-mediated, iterative cross-coupling approach to xanthomonadin polyenyl pigment analogues | 2019 |
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Dr Kate Harris
| Using Nature’s antioxidants as templates: Studies of synthetic xanthomonadin analogues and realising their potential as antioxidants | 2019 |
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Dr Kate Harris
| Approaches to styrenyl building blocks for the synthesis of polyene xanthomonadin and its analogues | 2018 |
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Dr Kate Harris
| Heck-Mizoroki coupling of vinyliodide and applications in the synthesis of dienes and trienes | 2015 |
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Dr Kate Harris
| Identification and optimisation of 7-azaindole PAK1 inhibitors with improved potency and kinase selectivity | 2014 |
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Dr Kate Harris
| Non-isoprenoid polyene natural products-structures and synthetic strategies | 2014 |
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Dr Kate Harris
| Synthesis of 3-(hetero)aryl tetrahydropyrazolo[3,4-c] pyridines by Suzuki-Miyaura cross-coupling methodology | 2014 |
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