Shangze Xu Lanyu Fan Dr Piotr Zaborniak Dr Ruidi Zhu Haoyuan Ji et al. | "Druggability" of the PAS domains of human PASK kinase, a therapeutic target for metabolic and liver disorders | 2025 |
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Pasquale Morese Ayaz Ahmad Dr Mathew Martin Dr Richard Noble Sara Pintar et al. | Factors affecting irreversible inhibition of EGFR and influence of chirality on covalent binding | 2025 |
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Dr Tarek Mamdouh Abdelghany Lanyu Fan Dr Satomi Miwa Dr Agnieszka Bronowska
| M8OI toxicity is associated with an inhibition of ubiquinone reduction by complex I in the mitochondrial electron transport chain | 2025 |
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Shangze Xu Dr Agnieszka Bronowska
| Inducible auto-phosphorylation regulates a widespread family of nucleotidyltransferase toxins | 2024 |
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Dr Tarek Abdelghany Lanyu Fan Ben Air Dr Alistair Leitch Dr Martin Cooke et al. | Methylimidazolium ionic liquids - A new class of forever chemicals with endocrine disrupting potential | 2024 |
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Daniil Baranov Dr Agnieszka Bronowska Dr Celine Cano Dr Michael Carroll Dr Paul Waddell et al. | Polymorphism in N-(3-Hydroxyphenyl)-3-methoxybenzamide | 2024 |
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Shangze Xu Matthew Kondal Dr Ayaz Ayaz Dr Ruidi Zhu Lanyu Fan et al. | Mechanistic Investigation of the Androgen Receptor DNA-Binding Domain and Modulation via Direct Interactions with DNA Abasic Sites: Understanding the Mechanisms Involved in Castration-Resistant Prostate Cancer | 2023 |
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Amelia Stennett Kallie Friston Professor Claire Harris Dr Adam Wollman Dr Agnieszka Bronowska et al. | The case for complement component 5 as a target in neurodegenerative disease | 2023 |
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Dr Tetsushi Kataura Gisela Otten Dr Yoana Rabanal Ruiz Francesca Urselli Dr Filippo Scialo et al. | NDP52 acts as a redox sensor in PINK1/Parkin-mediated mitophagy | 2022 |
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Dr Agnieszka Bronowska
| New Benchmark in DNA-Based Asymmetric Catalysis: Prevalence of Modified DNA/RNA Hybrid Systems | 2022 |
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Islam Al-Khawaldeh Dr Christine Basmadjian Dr Cinzia Bordoni Dr Suzannah Harnor Amy Heptinstall et al. | An alkynylpyrimidine-based covalent inhibitor that targets a unique cysteine in NF-κB-inducing kinase (NIK) | 2021 |
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Joao Victor de De Souza Cunha Dr Matthew Kondal Dr Piotr Zaborniak Dr Agnieszka Bronowska
| Controlling the heterodimerisation of the phytosulfokine receptor 1 (PSKR1) via island loop modulation | 2021 |
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Dr Joao Victor De Souza Cunha Dr Piotr Zaborniak Sylwia Reznikov Matthew Kondal Dr Ruidi Zhu et al. | Molecular Forces Governing the Biological Function of Per-Arnt-Sim-B (PAS-B) Domains: A Comparative Computational Study | 2021 |
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Danlin Liu Dr Ayaz Ayaz Dr Agnieszka Bronowska
| Structure, dynamics, and ligand recognition of human-specific chrfam7a (Dupα7) nicotinic receptor linked to neuropsychiatric disorders | 2021 |
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Joao Victor de De Souza Cunha Dr Agnieszka Bronowska
| Development of charge-augmented three-point water model (CAIPi3P) for accurate simulations of intrinsically disordered proteins | 2020 |
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Danlin Liu Professor Gavin Richardson Dr Fehmi Benli Dr Catherine Park Joao Victor de De Souza Cunha et al. | Inflammageing in the cardiovascular system: mechanisms, emerging targets, and novel therapeutic strategies | 2020 |
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Joao Victor de De Souza Cunha Dr Agnieszka Bronowska
| Molecular basis for the distinct functions of redox-active and FeS-transfering glutaredoxins | 2020 |
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Micael Karlberg Joao Victor de De Souza Cunha Lanyu Fan Arathi Kizhedath Dr Agnieszka Bronowska et al. | Qsar implementation for hic retention time prediction of mabs using fab structure: A comparison between structural representations | 2020 |
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Quico Sabanes Zariquiey Joao Victor de De Souza Cunha Dr Agnieszka Bronowska
| Cosolvent Analysis Toolkit (CAT): a robust hotspot identification platform for cosolvent simulations of proteins to expand the druggable proteome | 2019 |
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Joao Victor de De Souza Cunha Sylwia Reznikov Dr Ruidi Zhu Dr Agnieszka Bronowska
| Druggability assessment of mammalian Per-Arnt-Sim [PAS] domains using computational approaches | 2019 |
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Quico Sabanes Zariquiey Dr Agnieszka Bronowska
| If You Cannot Win Them, Join Them: Understanding New Ways to Target STAT3 by Small Molecules | 2019 |
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Dr Bernadette Carroll Diego Manni Dr Rhoda Stefanatos Fiona Menzies Dr Graham Smith et al. | Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis | 2018 |
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Sylwia Reznikov Dr Agnieszka Bronowska
| The aldehyde dehydrogenase AldA contributes to the hypochlorite defense and is redox-controlled by protein S-bacillithiolation in Staphylococcus aureus | 2018 |
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Dr Agnieszka Bronowska
| A proton relay enhances H2O2 sensitivity of GAPDH to facilitate metabolic adaptation. | 2015 |
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Dr Agnieszka Bronowska
| Allosteric regulation of focal adhesion kinase by PIP₂ and ATP. | 2015 |
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Dr Agnieszka Bronowska
| Force-sensitive autoinhibition of the von Willebrand factor is mediated by interdomain interactions | 2015 |
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Dr Agnieszka Bronowska
| Mechanism of Focal Adhesion Kinase Mechanosensing | 2015 |
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Dr Agnieszka Bronowska
| The influence of two-dimensional organization on peptide conformation | 2015 |
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Dr Agnieszka Bronowska
| Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes | 2014 |
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Dr Agnieszka Bronowska Professor Steve Homans
| Comparison of Entropic Contributions to Binding in a "Hydrophilic" versus "Hydrophobic" Ligand-Protein Interaction | 2010 |
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Dr Agnieszka Bronowska Professor Steve Homans
| Residual Ligand Entropy in the Binding of p-Substituted Benzenesulfonamide Ligands to Bovine Carbonic Anhydrase II | 2008 |
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Dr Agnieszka Bronowska Professor Steve Homans
| Global changes in local protein dynamics reduce the entropic cost of carbohydrate binding in the arabinose-binding protein | 2007 |
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Dr Agnieszka Bronowska Professor Steve Homans
| Contribution of ligand desolvation to binding thermodynamics in a ligand-protein interaction | 2006 |
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Dr Agnieszka Bronowska Professor Steve Homans
| Thermodynamic penalty arising from burial of a ligand polar group within a hydrophobic pocket of a protein receptor | 2006 |
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