Dr Kyle Thompson Dr Monika Olahova Dr Langping He Professor Wyatt Yue Professor Robert Taylor et al. | Bi-allelic variants in DAP3 result in reduced assembly of the mitoribosomal small subunit with altered apoptosis and a Perrault-syndrome-spectrum phenotype | 2025 |
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Dr Sabrina Mackinnon Professor Wyatt Yue
| Luminescence-based complementation assay to assess target engagement and cell permeability of glycolate oxidase (HAO1) inhibitors | 2025 |
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Dr Thomas McCorvie Dr Jiazhi Tang Dr Arnaud Basle Professor Wyatt Yue
| Architecture and regulation of filamentous human cystathionine beta-synthase | 2024 |
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Linnea Blomgren Dr Sabrina Mackinnon Dr Arnaud Basle Professor Wyatt Yue Dr Thomas McCorvie et al. | Dynamic inter-domain transformations mediate the allosteric regulation of human 5, 10-methylenetetrahydrofolate reductase | 2024 |
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Steven Hardwick Professor Wyatt Yue
| Structural basis for human mitochondrial tRNA maturation | 2024 |
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Dr Kyle Thompson Dr Monika Olahova Dr Langping He Dr Thomas McCorvie Professor Wyatt Yue et al. | Novel homozygous variants in PRORP expand the genotypic spectrum of combined oxidative phosphorylation deficiency 54 | 2023 |
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Dr Thomas McCorvie Professor Wyatt Yue
| The complex machinery of human cobalamin metabolism | 2023 |
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Professor Wyatt Yue
| Expanding the HPSE2 Genotypic Spectrum in Urofacial Syndrome, A Disease Featuring a Peripheral Neuropathy of the Urinary Bladder | 2022 |
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Professor Wyatt Yue
| FAS2FURIOUS: Moderate-Throughput Secreted Expression of Difficult Recombinant Proteins in Drosophila S2 Cells | 2022 |
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Dr Thomas McCorvie Professor Wyatt Yue
| Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate | 2022 |
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Dr Tetsushi Kataura Gisela Otten Dr Yoana Rabanal Ruiz Francesca Urselli Dr Filippo Scialo et al. | NDP52 acts as a redox sensor in PINK1/Parkin-mediated mitophagy | 2022 |
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Dr Sabrina Mackinnon Professor Wyatt Yue
| Novel Starting Points for Human Glycolate Oxidase Inhibitors, Revealed by Crystallography-Based Fragment Screening | 2022 |
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Professor Wyatt Yue
| Snapshots of actin and tubulin folding inside the TRiC chaperonin | 2022 |
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Dr Kyle Thompson Professor Wyatt Yue Professor Robert Taylor
| Bi-allelic variants in the mitochondrial RNase P subunit PRORP cause mitochondrial tRNA processing defects and pleiotropic multisystem presentations | 2021 |
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Professor Wyatt Yue
| Defining substrate selection by rhinoviral 2A proteinase through its crystal structure with the inhibitor zVAM.fmk | 2021 |
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Dr Sabrina Mackinnon Professor Wyatt Yue
| Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia. | 2021 |
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Professor Wyatt Yue
| Identification of small molecule allosteric modulators of 5,10-methylenetetrahydrofolate reductase (MTHFR) by targeting its unique regulatory domain | 2021 |
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Dr Sabrina Mackinnon Professor Wyatt Yue
| Naturally occurring cobalamin (B12) analogs can function as cofactors for human methylmalonyl-CoA mutase | 2021 |
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Professor Wyatt Yue
| Structural biochemistry coming of age in the study of genetic metabolic disorders | 2021 |
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Professor Wyatt Yue
| Structure and activation mechanism of the human liver-type glutaminase GLS2 | 2021 |
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Professor Wyatt Yue Dr Sabrina Mackinnon
| Succinyl-CoA:3-oxoacid coenzyme A transferase (SCOT) deficiency: A rare and potentially fatal metabolic disease | 2021 |
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