Publications by Professor Wyatt Yue - ePrints

Browsing publications by Professor Wyatt Yue.

Newcastle Authors	Title	Year
Dr Kyle Thompson Dr Monika Olahova Dr Langping He Professor Wyatt Yue Professor Robert Taylor et al.	Bi-allelic variants in DAP3 result in reduced assembly of the mitoribosomal small subunit with altered apoptosis and a Perrault-syndrome-spectrum phenotype	2025
Dr Sabrina Mackinnon Professor Wyatt Yue	Luminescence-based complementation assay to assess target engagement and cell permeability of glycolate oxidase (HAO1) inhibitors	2025
Dr Thomas McCorvie Dr Jiazhi Tang Dr Arnaud Basle Professor Wyatt Yue	Architecture and regulation of filamentous human cystathionine beta-synthase	2024
Linnea Blomgren Dr Sabrina Mackinnon Dr Arnaud Basle Professor Wyatt Yue Dr Thomas McCorvie et al.	Dynamic inter-domain transformations mediate the allosteric regulation of human 5, 10-methylenetetrahydrofolate reductase	2024
Steven Hardwick Professor Wyatt Yue	Structural basis for human mitochondrial tRNA maturation	2024
Dr Kyle Thompson Dr Monika Olahova Dr Langping He Dr Thomas McCorvie Professor Wyatt Yue et al.	Novel homozygous variants in PRORP expand the genotypic spectrum of combined oxidative phosphorylation deficiency 54	2023
Dr Thomas McCorvie Professor Wyatt Yue	The complex machinery of human cobalamin metabolism	2023
Professor Wyatt Yue	Expanding the HPSE2 Genotypic Spectrum in Urofacial Syndrome, A Disease Featuring a Peripheral Neuropathy of the Urinary Bladder	2022
Professor Wyatt Yue	FAS2FURIOUS: Moderate-Throughput Secreted Expression of Difficult Recombinant Proteins in Drosophila S2 Cells	2022
Dr Thomas McCorvie Professor Wyatt Yue	Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate	2022
Dr Tetsushi Kataura Gisela Otten Dr Yoana Rabanal Ruiz Francesca Urselli Dr Filippo Scialo et al.	NDP52 acts as a redox sensor in PINK1/Parkin-mediated mitophagy	2022
Dr Sabrina Mackinnon Professor Wyatt Yue	Novel Starting Points for Human Glycolate Oxidase Inhibitors, Revealed by Crystallography-Based Fragment Screening	2022
Professor Wyatt Yue	Snapshots of actin and tubulin folding inside the TRiC chaperonin	2022
Dr Kyle Thompson Professor Wyatt Yue Professor Robert Taylor	Bi-allelic variants in the mitochondrial RNase P subunit PRORP cause mitochondrial tRNA processing defects and pleiotropic multisystem presentations	2021
Professor Wyatt Yue	Defining substrate selection by rhinoviral 2A proteinase through its crystal structure with the inhibitor zVAM.fmk	2021
Dr Sabrina Mackinnon Professor Wyatt Yue	Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia.	2021
Professor Wyatt Yue	Identification of small molecule allosteric modulators of 5,10-methylenetetrahydrofolate reductase (MTHFR) by targeting its unique regulatory domain	2021
Dr Sabrina Mackinnon Professor Wyatt Yue	Naturally occurring cobalamin (B₁₂) analogs can function as cofactors for human methylmalonyl-CoA mutase	2021
Professor Wyatt Yue	Structural biochemistry coming of age in the study of genetic metabolic disorders	2021
Professor Wyatt Yue	Structure and activation mechanism of the human liver-type glutaminase GLS2	2021
Professor Wyatt Yue Dr Sabrina Mackinnon	Succinyl-CoA:3-oxoacid coenzyme A transferase (SCOT) deficiency: A rare and potentially fatal metabolic disease	2021