Dr James Stach
Professor Paul Race
| Complete genome sequences of two actinomycetes containing abyssomicin-like gene clusters: Kutzneria buriramensis DSM 45791 and Streptomyces sp. NL15-2K | 2025 |
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Dr James Stach
Professor Paul Race
| Antibiotic origami: selective formation of spirotetronates in abyssomicin biosynthesis | 2024 |
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Professor Paul Race
| Delineation of the complete reaction cycle of a natural Diels-Alderase | 2024 |
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Dr James Stach
Professor Paul Race
| Diversity and structure of the deep-sea sponge microbiome in the equatorial Atlantic Ocean | 2024 |
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Dr James Stach
Professor Paul Race
| Molecular basis of hyper-thermostability in the thermophilic archaeal aldolase MfnB | 2024 |
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Professor Paul Race
| An expandable, modular de novo protein platform for precision redox engineering | 2023 |
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Dr James Stach
Professor Paul Race
| Discovery and biosynthetic assessment of 'Streptomyces ortus' sp. nov. isolated from a deep-sea sponge | 2023 |
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Professor Paul Race
| Domain shuffling of a highly mutable ligand-binding fold drives adhesin generation across the bacterial kingdom | 2023 |
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Professor Paul Race
| Interrogation of an Enzyme Library Reveals the Catalytic Plasticity of Naturally Evolved [4+2] Cyclases | 2023 |
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Professor Paul Race
| Structure and Function of the α-Hydroxylation Bimodule of the Mupirocin Polyketide Synthase | 2023 |
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Dr James Stach
Professor Paul Race
| The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis | 2023 |
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Professor Paul Race
| Derivation of a Precise and Consistent Timeline for Antibiotic Development | 2022 |
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Professor Paul Race
| Expression, purification and preliminary characterisation of the choline transporter LicB from opportunistic bacterial pathogens | 2022 |
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Professor Paul Race
| Programmed Iteration Controls the Assembly of the Nonanoic Acid Side Chain of the Antibiotic Mupirocin | 2022 |
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Professor Paul Race
| SAXS reveals highly flexible interdomain linkers of tandem acyl carrier protein–thioesterase domains from a fungal nonreducing polyketide synthase | 2021 |
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Professor Paul Race
| A priming cassette generates hydroxylated acyl starter units in mupirocin and thiomarinol biosynthesis | 2020 |
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Professor Paul Race
| Computer-Aided Whole-Cell Design: Taking a Holistic Approach by Integrating Synthetic With Systems Biology | 2020 |
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Professor Paul Race
| Enzyme-catalysed polymer cross-linking: Biocatalytic tools for chemical biology, materials science and beyond | 2020 |
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Professor Paul Race
| Mixing and matching genes of marine and terrestrial origin in the biosynthesis of the mupirocin antibiotics | 2020 |
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Professor Paul Race
| Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide β-methyl branch incorporation | 2020 |
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Professor Paul Race
| The bristol sponge microbiome collection: A unique repository of deep-sea microorganisms and associated natural products | 2020 |
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Professor Paul Race
| The extremophilic pharmacy: Drug discovery at the limits of life | 2020 |
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Dr Daniel Frankel
Professor Paul Race
| The streptococcal multidomain fibrillar adhesin CshA has an elongated polymeric architecture | 2020 |
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Professor Paul Race
| Total Synthesis of Kalimantacin A | 2020 |
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Dr James Stach
Professor Paul Race
| A Natural Diels-Alder Biocatalyst Enables Efficient [4+2] Cycloaddition Under Harsh Reaction Conditions | 2019 |
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Dr Polly Moreland
Dr James Stach
Professor Paul Race
| An Esterase‐like Lyase Catalyzes Acetate Elimination in Spirotetronate/Spirotetramate Biosynthesis | 2019 |
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Dr James Stach
Professor Paul Race
| Cloning, expression, and purification of intact polyketide synthase modules | 2019 |
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Professor Paul Race
| Control of β-Branching in Kalimantacin Biosynthesis: Application of 13C NMR to Polyketide Programming | 2019 |
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Professor Paul Race
| Designer artificial membrane binding proteins to direct stem cells to the myocardium | 2019 |
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Professor Paul Race
| Towards machine learning approaches for predicting the self-healing efficiency of materials | 2019 |
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Professor Paul Race
| A Rieske oxygenase/epoxide hydrolase-catalysed reaction cascade creates oxygen heterocycles in mupirocin biosynthesis | 2018 |
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Professor Paul Race
| Fine Tuning of Antibiotic Activity by a Tailoring Hydroxylase in a Trans-AT Polyketide Synthase Pathway | 2018 |
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Professor Paul Race
| Elucidation of the relative and absolute stereochemistry of the kalimantacin/batumin antibiotics | 2017 |
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Professor Paul Race
| Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics | 2017 |
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Professor Paul Race
| Studies of recombinant TWA1 reveal constitutive dimerization | 2017 |
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Professor Paul Race
| Synthetic biology: A game changer? | 2017 |
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Professor Paul Race
| The Streptococcus gordonii adhesin CshA protein binds host fibronectin via a catch-clamp mechanism | 2017 |
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Professor Paul Race
| BrisSynBio: A BBSRC/EPsrc-funded synthetic biology research centre | 2016 |
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Professor Paul Race
| Structural and functional analysis of cell wall-anchored polypeptide adhesin BspA in Streptococcus agalactiae | 2016 |
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Professor Paul Race
| The assembly line enzymology of polyketide biosynthesis | 2016 |
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Dr James Stach
Professor Paul Race
| The Catalytic Mechanism of a Natural Diels-Alderase Revealed in Molecular Detail | 2016 |
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Professor Paul Race
| Iintegration of the Rac1- and actin-binding properties of coronin-1C | 2015 |
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Professor Paul Race
| Kinetic characterisation of the FAD dependent monooxygenase TropB and investigation of its biotransformation potential | 2015 |
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Professor Paul Race
| Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure | 2014 |
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Professor Paul Race
| Progress challenges and opportunities for the re-engineering of trans-AT polyketide synthases | 2014 |
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Professor Paul Race
| Improving the success rate of protein crystallization by random microseed matrix screening | 2013 |
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Dr Fiona Cuskin
Dr Alexandra Solovyova
Professor Rick Lewis
Professor Paul Race
| Crystallization and preliminary X-ray analysis of the bacillaene synthase trans-acting acyltransferase PksC | 2011 |
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Dr Alexandra Solovyova
Jonathan Pointon
Professor Paul Race
Dr Wendy Smith
Professor Michael Kehoe
et al. | Solution structure of the major (Spy0128) and minor (Spy0125 and Spy0130) pili subunits from Streptococcus pyogenes | 2010 |
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Professor Paul Race
Dr Wendy Smith
Professor Michael Kehoe
Dr Mark Banfield
| Crystal structure of Streptococcus pyogenes sortase A: implications for sortase mechanism | 2009 |
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Professor Paul Race
| Crystal structures of Cif from bacterial pathogens Photorhabdus luminescens and Burkholderia pseudomallei | 2009 |
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Dr Jon Marles-Wright
Dr Olivier Delumeau
Dr Susan Firbank
Dr James Murray
Dr Joseph Newman
et al. | Molecular architecture of the "stressosome," a signal integration and transduction hub | 2008 |
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Professor Paul Race
Dr Alexandra Solovyova
Dr Mark Banfield
| Conformation of the EPEC Tir protein in solution: Investigating the impact of serine phosphorylation at positions 434/463 | 2007 |
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Professor Paul Race
| Kinetic and Structural Characterisation of Escherichia coli Nitroreductase Mutants Showing Improved Efficacy for the Prodrug Substrate CB1954 | 2007 |
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Professor Paul Race
Professor Jeremy Lakey
Dr Mark Banfield
| Insertion of the enteropathogenic Escherichia coli Tir virulence protein into membranes in vitro | 2006 |
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Amy Openshaw
Professor Paul Race
Dr Mark Banfield
| Crystal structure of SmcL, a bacterial neutral sphingomyelinase C from Listeria | 2005 |
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Professor Paul Race
| Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone: Reversed binding orientations in different redox states of the enzyme | 2005 |
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Professor Paul Race
| Nitroreductase: A prodrug-activating enzyme for cancer gene therapy | 2004 |
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Professor Paul Race
| Generation of Escherichia coli nitroreductase mutants conferring improved cell sensitization to the prodrug CB1954 | 2003 |
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Professor Paul Race
| Nitroaryl Phosphoramides as Novel Prodrugs for E. coli Nitroreductase Activation in Enzyme Prodrug Therapy | 2003 |
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