Publications by Professor Paul Race - ePrints

Browsing publications by Professor Paul Race.

Newcastle Authors	Title	Year
Dr James Stach Professor Paul Race	Antibiotic origami: selective formation of spirotetronates in abyssomicin biosynthesis	2024
Professor Paul Race	Delineation of the complete reaction cycle of a natural Diels-Alderase	2024
Dr James Stach Professor Paul Race	Diversity and structure of the deep-sea sponge microbiome in the equatorial Atlantic Ocean	2024
Dr James Stach Professor Paul Race	Molecular basis of hyper-thermostability in the thermophilic archaeal aldolase MfnB	2024
Professor Paul Race	An expandable, modular de novo protein platform for precision redox engineering	2023
Dr James Stach Professor Paul Race	Discovery and biosynthetic assessment of 'Streptomyces ortus' sp. nov. isolated from a deep-sea sponge	2023
Professor Paul Race	Domain shuffling of a highly mutable ligand-binding fold drives adhesin generation across the bacterial kingdom	2023
Professor Paul Race	Interrogation of an Enzyme Library Reveals the Catalytic Plasticity of Naturally Evolved [4+2] Cyclases	2023
Professor Paul Race	Structure and Function of the α-Hydroxylation Bimodule of the Mupirocin Polyketide Synthase	2023
Dr James Stach Professor Paul Race	The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis	2023
Professor Paul Race	Derivation of a Precise and Consistent Timeline for Antibiotic Development	2022
Professor Paul Race	Expression, purification and preliminary characterisation of the choline transporter LicB from opportunistic bacterial pathogens	2022
Professor Paul Race	Programmed Iteration Controls the Assembly of the Nonanoic Acid Side Chain of the Antibiotic Mupirocin	2022
Professor Paul Race	SAXS reveals highly flexible interdomain linkers of tandem acyl carrier protein–thioesterase domains from a fungal nonreducing polyketide synthase	2021
Professor Paul Race	A priming cassette generates hydroxylated acyl starter units in mupirocin and thiomarinol biosynthesis	2020
Professor Paul Race	Computer-Aided Whole-Cell Design: Taking a Holistic Approach by Integrating Synthetic With Systems Biology	2020
Professor Paul Race	Enzyme-catalysed polymer cross-linking: Biocatalytic tools for chemical biology, materials science and beyond	2020
Professor Paul Race	Mixing and matching genes of marine and terrestrial origin in the biosynthesis of the mupirocin antibiotics	2020
Professor Paul Race	Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide β-methyl branch incorporation	2020
Professor Paul Race	The bristol sponge microbiome collection: A unique repository of deep-sea microorganisms and associated natural products	2020
Professor Paul Race	The extremophilic pharmacy: Drug discovery at the limits of life	2020
Dr Daniel Frankel Professor Paul Race	The streptococcal multidomain fibrillar adhesin CshA has an elongated polymeric architecture	2020
Professor Paul Race	Total Synthesis of Kalimantacin A	2020
Dr James Stach Professor Paul Race	A Natural Diels-Alder Biocatalyst Enables Efficient [4+2] Cycloaddition Under Harsh Reaction Conditions	2019
Dr Polly Moreland Dr James Stach Professor Paul Race	An Esterase‐like Lyase Catalyzes Acetate Elimination in Spirotetronate/Spirotetramate Biosynthesis	2019
Dr James Stach Professor Paul Race	Cloning, expression, and purification of intact polyketide synthase modules	2019
Professor Paul Race	Control of β-Branching in Kalimantacin Biosynthesis: Application of 13C NMR to Polyketide Programming	2019
Professor Paul Race	Designer artificial membrane binding proteins to direct stem cells to the myocardium	2019
Professor Paul Race	Towards machine learning approaches for predicting the self-healing efficiency of materials	2019
Professor Paul Race	A Rieske oxygenase/epoxide hydrolase-catalysed reaction cascade creates oxygen heterocycles in mupirocin biosynthesis	2018
Professor Paul Race	Fine Tuning of Antibiotic Activity by a Tailoring Hydroxylase in a Trans-AT Polyketide Synthase Pathway	2018
Professor Paul Race	Elucidation of the relative and absolute stereochemistry of the kalimantacin/batumin antibiotics	2017
Professor Paul Race	Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics	2017
Professor Paul Race	Studies of recombinant TWA1 reveal constitutive dimerization	2017
Professor Paul Race	Synthetic biology: A game changer?	2017
Professor Paul Race	The Streptococcus gordonii adhesin CshA protein binds host fibronectin via a catch-clamp mechanism	2017
Professor Paul Race	BrisSynBio: A BBSRC/EPsrc-funded synthetic biology research centre	2016
Professor Paul Race	Structural and functional analysis of cell wall-anchored polypeptide adhesin BspA in Streptococcus agalactiae	2016
Professor Paul Race	The assembly line enzymology of polyketide biosynthesis	2016
Dr James Stach Professor Paul Race	The Catalytic Mechanism of a Natural Diels-Alderase Revealed in Molecular Detail	2016
Professor Paul Race	Iintegration of the Rac1- and actin-binding properties of coronin-1C	2015
Professor Paul Race	Kinetic characterisation of the FAD dependent monooxygenase TropB and investigation of its biotransformation potential	2015
Professor Paul Race	Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure	2014
Professor Paul Race	Progress challenges and opportunities for the re-engineering of trans-AT polyketide synthases	2014
Professor Paul Race	Improving the success rate of protein crystallization by random microseed matrix screening	2013
Dr Fiona Cuskin Dr Alexandra Solovyova Professor Rick Lewis Professor Paul Race	Crystallization and preliminary X-ray analysis of the bacillaene synthase trans-acting acyltransferase PksC	2011
Dr Alexandra Solovyova Jonathan Pointon Professor Paul Race Dr Wendy Smith Professor Michael Kehoe et al.	Solution structure of the major (Spy0128) and minor (Spy0125 and Spy0130) pili subunits from Streptococcus pyogenes	2010
Professor Paul Race Dr Wendy Smith Professor Michael Kehoe Dr Mark Banfield	Crystal structure of Streptococcus pyogenes sortase A: implications for sortase mechanism	2009
Professor Paul Race	Crystal structures of Cif from bacterial pathogens Photorhabdus luminescens and Burkholderia pseudomallei	2009
Dr Jon Marles-Wright Dr Olivier Delumeau Dr Susan Firbank Dr James Murray Dr Joseph Newman et al.	Molecular architecture of the "stressosome," a signal integration and transduction hub	2008
Professor Paul Race Dr Alexandra Solovyova Dr Mark Banfield	Conformation of the EPEC Tir protein in solution: Investigating the impact of serine phosphorylation at positions 434/463	2007
Professor Paul Race	Kinetic and Structural Characterisation of Escherichia coli Nitroreductase Mutants Showing Improved Efficacy for the Prodrug Substrate CB1954	2007
Professor Paul Race Professor Jeremy Lakey Dr Mark Banfield	Insertion of the enteropathogenic Escherichia coli Tir virulence protein into membranes in vitro	2006
Amy Openshaw Professor Paul Race Dr Mark Banfield	Crystal structure of SmcL, a bacterial neutral sphingomyelinase C from Listeria	2005
Professor Paul Race	Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone: Reversed binding orientations in different redox states of the enzyme	2005
Professor Paul Race	Nitroreductase: A prodrug-activating enzyme for cancer gene therapy	2004
Professor Paul Race	Generation of Escherichia coli nitroreductase mutants conferring improved cell sensitization to the prodrug CB1954	2003
Professor Paul Race	Nitroaryl Phosphoramides as Novel Prodrugs for E. coli Nitroreductase Activation in Enzyme Prodrug Therapy	2003