Publications by Professor Bruce Westley - ePrints

Browsing publications by Professor Bruce Westley.

Newcastle Authors	Title	Year
Dr Felicity May Professor Bruce Westley	TFF3 is a valuable predictive biomarker of endocrine response in metastatic breast cancer	2015
Ahmed Ahmed Andrew Griffiths Professor Bruce Westley Dr Felicity May	TFF3 Is a Normal Breast Epithelial Protein and Is Associated with Differentiated Phenotype in Early Breast Cancer but Predisposes to Invasion and Metastasis in Advanced Disease	2012
Dr Zoe Davison Dr Gail de Blaquiere Professor Bruce Westley Dr Felicity May	Insulin-like Growth Factor-Dependent Proliferation and Survival of Triple-Negative Breast Cancer Cells: Implications for Therapy	2011
Dr Felicity May Professor Bruce Westley	Trefoil Factor 1 Stimulates Both Pancreatic Cancer and Stellate Cells and Increases Metastasis	2011
Paul Wright Dr Felicity May Dr Steven Darby Rehan Saif Professor Thomas Lennard et al.	Estrogen regulates vesicle trafficking gene expression in EFF-3, EFM-19 and MCF-7 breast cancer cells	2009
Dr Gail de Blaquiere Dr Felicity May Professor Bruce Westley	Increased expression of both insulin receptor substrates 1 and 2 confers increased sensitivity to IGF-1 stimulated cell migration	2009
Dr Felicity May Professor Michael Griffin Professor Bruce Westley	The trefoil factor interacting protein TFIZ1 binds the trefoil protein TFF1 preferentially in normal gastric mucosal cells but the co-expression of these proteins is deregulated in gastric cancer	2009
Dr Felicity May Professor Bruce Westley	Helicobacter pylori Lipopolysaccharide Interacts With TFF1 in a pH-Dependent Manner	2008
Professor Bruce Westley Dr Felicity May	Decreased expression of gastrokine 1 and the trefoil factor interacting protein TFIZ1/GKN2 in gastric cancer: Influence of tumor histology and relationship to prognosis	2008
Dr Felicity May Professor Bruce Westley	Increased TFF1 trefoil protein expression in Opisthorchis viverrini-associated cholangiocarcinoma is important for invasive promotion	2007
Dr Felicity May Professor Bruce Westley	Rough-form lipopolysaccharide of Helicobacter pylori promotes adhesion to trefoil protein TFF1 - a pH regulated interaction	2007
Emerita Professor Julia Newton Professor Bruce Westley Dr Felicity May	Human pancreatic polypeptide has a marked diurnal rhythm that is affected by ageing and is associated with the gastric TFF2 circadian rhythm	2006
Professor Bruce Westley Dr Felicity May	Identification of steroid hormone-regulated genes in breast cancer	2006
Dr Gail de Blaquiere Dr Felicity May Professor Bruce Westley	Insulin-like growth factor signalling in oestrogen nonresponsive breast cancer cells	2006
Professor Bruce Westley Dr Felicity May	Identification of human urinary trefoil factor 1 as a novel calcium oxalate crystal growth inhibitor	2005
Paul Wright Dr Felicity May Professor Bruce Westley Professor Thomas Lennard	Identification of oestrogen-regulated genes in breast cancer using DNA microarrays	2005
Paul Wright Dr Felicity May Professor Bruce Westley Professor Thomas Lennard	Identification of oestrogen-regulated genes in breast cancer using DNA microarrays	2005
Professor Bruce Westley Professor Michael Griffin Dr Felicity May	Interaction between TFF1, a gastric tumor suppressor trefoil protein, and TFIZ1, a brichos domain-containing protein with homology to SP-C	2005
Dr Emma Johns Emerita Professor Julia Newton Professor Bruce Westley Dr Felicity May	The diurnal rhythm of the cytoprotective human trefoil protein TFF2 is reduced by factors associated with gastric mucosal damage: Ageing, Helicobacter pylori Infection, and sleep deprivation	2005
Professor Bruce Westley Dr Felicity May	Trefoil factor family mRNA and protein expression in pterygium	2005
Dr Emma Johns Emerita Professor Julia Newton Professor Bruce Westley Dr Felicity May	Ageing and H pylori infection alter the diurnal rhythm of the gastric cytoprotective trefoil protein TFF2	2004
Dr Meiyi Pu Dr Felicity May Dr Marie-Helene Ruchaud Professor Bruce Westley	Development of a two-site ELISA assay for the dimeric form of human TFF1	2004
Dr Felicity May Dr Sara Prest Professor Bruce Westley	Expression and motogenic activity of TFF2 in human breast cancer cells	2004
Dr Felicity May Professor Bruce Westley	Helicobacter pylori interacts with the human single-domain trefoil protein TFF1	2004
Dr Meiyi Pu Professor Bruce Westley Dr Felicity May	Synergistic effects of systemic trefoil factor family 1 (TFF1) peptide and epidermal growth factor in a rat model of colitis	2004
Dr Marie-Helene Ruchaud Professor Bruce Westley Dr Felicity May	The trefoil protein TFF1 is bound to MUC5AC in human gastric mucosa	2004
Dr Felicity May Professor Bruce Westley	Trefoil factor family peptide 3 prevents the development and promotes healing of ischemia-reperfusion injury in weanling rats	2004
Dr Emma Johns Emerita Professor Julia Newton Professor Bruce Westley Dr Felicity May	Expression of the cytoprotective trefoil protein TFF2 in human gastric and duodenal biopsies	2003
Professor Bruce Westley Dr Felicity May	Selective abrogation of the proinvasive activity of the trefoil peptides pS2 and spasmolytic polypeptide by disruption of the EGF receptor signaling pathways in kidney and colonic cancer cells	2003
Dr Felicity May Professor Bruce Westley	Solution Structure of the Disulfide-Linked Dimer of Human Intestinal Trefoil Factor (TFF3): The Intermolecular Orientation and Interactions Are Markedly Different from Those of Other Dimeric Trefoil Proteins	2003
Dr Felicity May Dr Stephen Church Professor Bruce Westley	The closely related estrogen-regulated trefoil proteins TFF1 and TFF3 have markedly different hydrodynamic properties, overall charge, and distribution of surface charge	2003
Professor Bruce Westley Dr Felicity May	Trefoil peptides as proangiogenic factors in vivo and in vitro: Implication of cyclooxygenase-2 and EGF receptor signaling	2003
Dr Sara Prest Dr Felicity May Professor Bruce Westley	The estrogen-regulated protein, TFF1, stimulates migration of human breast cancer cells	2002
Professor Bruce Westley Dr Felicity May	Activation of cellular invasion by trefoil peptides and src is mediated by cyclooxygenase- and thromboxane A2 receptor-dependent signaling pathways	2001
Emerita Professor Julia Newton Professor Bruce Westley Dr Felicity May	Dramatic diurnal variation in the concentration of the human trefoil peptide TFF2 in gastric juice	2001
Moira Crosier Dr Debbie Scott Dr Felicity May Professor Bruce Westley	High expression of the trefoil protein TFF1 in interval breast cancers	2001
Dr Felicity May Professor Bruce Westley	Induction of scattering and cellular invasion by trefoil peptides in src- and RhoA-transformed kidney and colonic epithelial cells	2001
Professor Bruce Westley Dr Felicity May	The solution structure of the disulphide-linked homodimer of the human trefoil protein TFF1	2001
Dr Felicity May Professor Bruce Westley	Insulin receptor substrate-1 expression is regulated by estrogen in the MCF-7 human breast cancer cell line	2000
Emerita Professor Julia Newton Professor Bruce Westley Dr Felicity May	The human trefoil peptide, TFF1, is present in different molecular forms that are intimately associated with mucus in normal stomach	2000
Professor Bruce Westley Dr Felicity May	High-resolution solution structure of human pNR-2/pS2: A single trefoil motif protein	1997
Professor Debra Bevitt Emeritus Professor Geoffrey Toms Professor Thomas Lennard Professor Bruce Westley Dr Brian Angus et al.	New monoclonal antibodies to oestrogen and progesterone receptors effective for paraffin section immunohistochemistry	1997
Dr Mary Carr Dr Felicity May Professor Thomas Lennard Professor Bruce Westley	Determination of estrogen responsiveness of breast cancer by competitive reverse transcription polymerase chain reaction	1995
Professor Bruce Westley Dr Felicity May	Insulin like growth factors: the unrecognised oncogenes	1995
Professor Bruce Westley Dr Felicity May	In-vitro development of tamoxifen resistance	1995
Dr Felicity May Professor Bruce Westley	Mutations at position-11 and postition-60 of insulin like growth factor 1 reveal differences between its interactions with the type-I insulin like growth factor receptor and insulin receptor	1995
Dr Felicity May Professor Bruce Westley	Production and comparison of mature single domain trefoil peptides PNR-2/PS2 CYS(58) and PNR-2/PS2 SER(58)	1995
Dr Felicity May Professor Bruce Westley	Mitogenic activity of procathepsin-D purified from conditioned medium of breast cancer cells by affinity chromatography on pepstatinyl agarose	1994
Professor Bruce Westley Dr Felicity May	Role of insulin like growth factors in steroid modulated proliferation	1994
Diana Levett Professor Thomas Lennard Professor Bruce Westley Dr Felicity May	INT-2 amplification in breast cancer: association with decreased survival and relationship to amplification of C-ERBB-2 and C-MYC	1993
Professor Bruce Westley Dr Felicity May	Isolation and characterization of an estrogen responsice breast cancer cell line, EFF-3	1993
Dr Felicity May Dave Smith Professor Bruce Westley	The human cathepsin d-encoding is transcribed from an estrogen regulated and a constitutive start point	1993
Dr Felicity May Professor Bruce Westley	Type-I IGF receptor and acquired tamoxifen resistance in estrogen responsive human breast cancer cells	1993
Professor Bruce Westley Dr Felicity May	Modulation of the proliferative response of breast cancer cells to growth factors by estrogen	1992
Dr Mark Bennett Diana Levett Dr Felicity May Professor Bruce Westley	Expresison of the PNR-2 PS2 protein in diverse human epithelial tumors	1991
Dr Felicity May Professor Bruce Westley Dr Brian Angus Professor Thomas Lennard	Expression of antimetastatic gene NM23	1991
Dr Felicity May Professor Bruce Westley Dr Brian Angus Professor Thomas Lennard	Expression of the antimetastatic gene NM23 in human breast cancer: an association with good prognosis	1991
Dr Ujjal Mallick Professor Bruce Westley Dr Felicity May	PNR-2 PS2 immunohistochemical staining in breast cancer: correlation with prognostic factors and endocrine response	1991
Dr Brian Angus Diana Levett Dr Sarah Johnson Professor Thomas Lennard Dr Felicity May et al.	The prognostic significance of the lysosomal protease cathepsin-D in human breast cancer - an immunohistochemical study	1991
Dr Felicity May Professor Bruce Westley	Antipeptide antibodies against the PNR-2-estrogen regulated protein of human breast cancer cells and detection of PNR-2 expression in norman tissue by immunohistochemistry	1991
Dr Brian Angus Professor Bruce Westley Dr Felicity May	Prognostic significance of the estrogen-regulated protein, cathepsin D, in breast cancer. An immunohistochemical study.	1990
Professor Thomas Lennard Dr Felicity May Professor Bruce Westley	Expression of the estrogen regulated PNR-2 messenger RNA in human breast cancer: relation to estrogen receptor messenger RNA levels and response to tamoxifen therapy	1990
Dr Mark Bennett Dr Felicity May Professor Bruce Westley	Expression of the PNR-2/PS2 in nonmammary human cancer: an immunohistochemical study	1990
Dr Ian Corbett Dr Brian Angus Dr Felicity May Professor Bruce Westley	NCL-CB11 anto c-erbb-2 monoclonal antibody characterization and correlation with gene amplification	1990
Dr Ian Corbett Dr Brian Angus Dr Felicity May Professor Bruce Westley	NCL-CB11, a new monoclonal antibody recognizing the internal domain of the c-erbb-2 oncogene protein effective for use on formalin fixed, paraffin embedded tissue	1990
Dr Felicity May Professor Bruce Westley	Role of insulin like growth factors and the type I insulin like growth factor receptor in the estrogen stimulated proliferation of human breast cancer cells	1990
Dr Felicity May Professor Bruce Westley Dr Brian Angus Professor Thomas Lennard	The antimetastatic gene NM23: its expression in human breast cancers	1990
Professor Bruce Westley Dr Felicity May	Effects of estrogen and the antioestrogens, tamoxifen and LY117018, on 4 estrogen regulated RNAs in the EFM-19 breast cancer cell line	1989
Professor Bruce Westley Dr Felicity May	Estrogenic activity of tamoxifen and its metabolites on gene regulation and cell proliferation in MCF-7 breast cancer cells	1989
Dr Felicity May Professor Bruce Westley	Regulation of progesterone receptor messenger RNA by estradiol and antioestrogens in breast cancer cell lines	1989
Dr Felicity May Professor Bruce Westley	Characterization of sequences related to the mouse mammary tumor virus that are specific to MCF-7 breast cancer cells	1989
Dr Felicity May Professor Bruce Westley	Effects of the antiestrogen, ICI-164,384 on estrogen enduced RNAS in MCF-7 cells	1989
Dr Felicity May Professor Bruce Westley	Effects of the antioestrogen ICI-164,384 on estrogen induced RNAs in MCF-7 cells	1988
Professor Bruce Westley Dr Felicity May	Estimation of estrogen receptor messenger RNA levels in human breast tumors	1988
Professor Bruce Westley Dr Felicity May	Estrogen regulates estrogen receptor messenger RNA levels in an estrogen responsive human breast cancer cell line	1988
Dr Felicity May Professor Bruce Westley	Expression of estrogen regulated PNR-2 messenger RNA in human breast cancer	1988
Dr Felicity May Professor Bruce Westley	Expression of human sequences related to those of mouse mammary tumor virus	1988
Dr Felicity May Professor Bruce Westley	Identification and characterization of estrogen regulated RNAs in human breast cancer cells	1988
Professor Bruce Westley Dr Felicity May	Measurement of estrogen receptor messenger RNA levels in human breast tumors	1988
Professor Bruce Westley Dr Felicity May	The effect of the antiestrogen tamoxifen and its metabolites on the expression of estrogen regulated genes in human breast cancer cells	1987
Professor Bruce Westley Dr Felicity May	The expression of human DNA sequences related to mouse mammary tumor virus	1987
Dr Felicity May Professor Bruce Westley	Effects of tamoxifen and 4-hydroxytamoxifen on the PNR-1 and PNR-2 estrogen regulated RNAs in human breast cancer cells	1987
Professor Bruce Westley Dr Felicity May	Estrogen regulates cathepsin-D messenger RNA levels in edtrogen responsive human breast cancer cells	1987
Dr Felicity May Professor Bruce Westley	Structure of a human retroviral sequence related to mouse mammary tumor virus	1986
Dr Felicity May Professor Bruce Westley	Cloning of estrogen regulated messenger RNA sequences from human breast cancer cells	1986