Publications by Professor Pamela Shaw - ePrints

Browsing publications by Professor Pamela Shaw.

Newcastle Authors	Title	Year
Professor Pamela Shaw Professor Fiona Matthews Professor Carol Brayne	Type 2 Diabetes Mellitus-Associated Transcriptome Alterations in Cortical Neurones and Associated Neurovascular Unit Cells in the Ageing Brain	2021
Dr Connor Richardson Professor Carol Brayne Professor Pamela Shaw Professor Fiona Matthews	Advanced Glycation End Product Formation in Human Cerebral Cortex Increases with Alzheimer-type Neuropathologic Changes but is Not Independently Associated with Dementia in a Population-Derived Aging Brain Cohort	2020
Dr Nick Steen Professor Pamela Shaw	Regionality of disease progression predicts prognosis in amyotrophic lateral sclerosis	2015
Professor Stephen Bourke Professor Pamela Shaw	Safety and efficacy of diaphragm pacing in patients with respiratory insufficiency due to amyotrophic lateral sclerosis (DiPALS): a multicentre, open-label, randomised controlled trial	2015
Professor Pamela Shaw Dr Nick Steen	Health utility decreases with increasing clinical stage in amyotrophic lateral sclerosis	2014
Dr Timothy Peel Professor Pamela Shaw Emeritus Professor John Gibson Professor Stephen Bourke	Non-invasive ventilation in motor neuron disease: an update of current UK practice	2012
Professor Stephen Bourke Dr Timothy Peel Emeritus Professor John Gibson Professor Pamela Shaw	The changing landscape of non-invasive ventilation in amyotrophic lateral sclerosis	2012
Professor Pamela Shaw Dr Nick Steen	Protocol for a double-blind randomised placebo-controlled trial of lithium carbonate in patients with amyotrophic Lateral Sclerosis (LiCALS) [Eudract number: 2008-006891-31]	2011
Dr Timothy Peel Professor Pamela Shaw Professor Stephen Bourke	Non-invasive ventilation in motor neurone disease: an update of current UK practice [abstract]	2010
Professor John O'Brien Dr Robert Barber Professor Raj Kalaria Professor Carol Brayne Professor Pamela Shaw et al.	Microarray RNA Expression Analysis of Cerebral White Matter Lesions Reveals Changes in Multiple Functional Pathways	2009
Dr Paula Heath Professor Carol Brayne Dr Robert Barber Professor Raj Kalaria Professor John O'Brien et al.	Microarray gene expression analysis of deep subcortical lesions in the ageing brain reveals changes in multiple functional pathways	2008
Geoffrey Taylor Professor Pamela Shaw Emeritus Professor Doug Turnbull Professor Robert Taylor	Investigation of the mitochondrial genome in patients with atypical motor neuron disease	2007
Dr Phillip Byrne Professor Patrick Chinnery Dr Angela Pyle Professor Pamela Shaw	Linkage to a known gene but no mutation identified: Comprehensive reanalysis of SPG4 HSP pedigrees reveals large deletions as the sole cause	2007
Dr Paula Heath Professor Carol Brayne Dr Robert Barber Professor Raj Kalaria Professor John O'Brien et al.	Microarray gene expression profiling of deep subcortical lesions in the ageing brain	2007
Professor John O'Brien Dr Robert Barber Professor Raj Kalaria Professor Carol Brayne Professor Pamela Shaw et al.	Microglial activation in white matter lesions and nonlesional white matter of ageing brains	2007
Professor John O'Brien Dr Robert Barber Professor Raj Kalaria Professor Carol Brayne Professor Pamela Shaw et al.	Microglial activation in white matter of the ageing brain	2007
Professor Patrick Chinnery Dr Catherine Mowbray Dr Hannah Elliott Dr Joanna Elson Professor Pamela Shaw et al.	Mitochondrial DNA haplogroups and amyotrophic lateral sclerosis	2007
Professor John O'Brien Dr Robert Barber Professor Raj Kalaria Professor Carol Brayne Professor Pamela Shaw et al.	White matter lesions in an unselected cohort of the elderly: Astrocytic, microglial and oligodendrocyte precursor cell responses	2007
Professor Stephen Bourke Dr Timothy Williams Dr Robert Bullock Professor Pamela Shaw Emeritus Professor John Gibson et al.	Effects of non-invasive ventilation on survival and quality of life in patients with amyotrophic lateral sclerosis: A randomised controlled trial	2006
Professor John O'Brien Dr Robert Barber Professor Raj Kalaria Professor Carol Brayne Professor Pamela Shaw et al.	Glial cell pathology of periventricular and deep white matter lesions in the ageing brain	2006
Professor Carol Brayne Professor John O'Brien Professor Raj Kalaria Professor Pamela Shaw	Molecular markers of tissue hypoxia and glial pathology associated with incidental white matter lesions in the ageing brain	2006
Professor Carol Brayne Dr Robert Barber Professor Raj Kalaria Professor Pamela Shaw Professor John O'Brien et al.	Molecular markers of tissue hypoxia are associated with deep subcortical white matter lesions in the ageing brain	2006
Dr Gillian Borthwick Professor Robert Taylor Dr Timothy Walls Dr Kasia Tonska Geoffrey Taylor et al.	Motor neuron disease in a patient with a mitochondrial tRNA^lle mutation	2006
Professor Stephen Bourke Dr Robert Bullock Professor Pamela Shaw Emeritus Professor John Gibson	Non-invasive ventilation in amyotrophic lateral sclerosis	2006
Professor Stephen Bourke Dr Robert Bullock Professor Pamela Shaw	A randomised controlled trial of non-invasive ventilation (NIV) in motor neurone disease (MND)	2005
Emeritus Professor John Kirby Louise Ward Professor Pamela Shaw	Screening of the regulatory and coding regions of vascular endothelial growth factor in amyotrophic lateral sclerosis	2005
Professor Stephen Bourke Professor Pamela Shaw Dr Robert Bullock Emeritus Professor John Gibson	Randomised controlled trial of now invasive ventilation in motor neurone disease	2004
Professor Stephen Bourke Emerita Professor Elaine McColl Professor Pamela Shaw Emeritus Professor John Gibson	Validation of quality of life instruments in ALS	2004
Emerita Professor Katherine Bushby Professor Pamela Shaw	Hereditary Spastic Paraparesis: Disrupted Intracellular Transport Associated with Spastin Mutation	2003
Professor Robert Taylor Christopher Hayes Emerita Professor Katherine Bushby Emeritus Professor Doug Turnbull Professor Pamela Shaw et al.	Investigation of mitochondrial function in hereditary spastic paraparesis	2003
Professor Stephen Bourke Dr Robert Bullock Professor Pamela Shaw Emeritus Professor John Gibson	Noninvasive ventilation in ALS: Indications and effect on quality of life	2003
Dr Janine Tomkins Emerita Professor Katherine Bushby Professor Pamela Shaw	Spastin and paraplegin gene analysis in selected cases of motor neurone disease (MND)	2003
Professor Stephen Bourke Professor Pamela Shaw Dr Robert Bullock	Criteria for initiating non-invasive ventilation in motor neuron disease	2002
Dr Mark Cookson Fiona Menzies Dr Philip Manning Professor Christopher Eggett Emeritus Professor Calum McNeil et al.	Cu/Zn superoxide dismutase (SOD1) mutations associated with familial amyotrophic lateral sclerosis (ALS) affect cellular free radical release in the presence of oxidative stress	2002
Emeritus Professor John Kirby Fiona Menzies Dr Mark Cookson Emerita Professor Katherine Bushby Professor Pamela Shaw et al.	Differential gene expression in a cell culture model of SOD1-related familial motor neurone disease	2002
Professor Robert Taylor Christine Hayes Emerita Professor Katherine Bushby Emeritus Professor Doug Turnbull Professor Pamela Shaw et al.	Investigation of mitochondrial function in hereditary spastic paraparesis	2002
Fiona Menzies Dr Mark Cookson Professor Robert Taylor Emeritus Professor Doug Turnbull Professor Zofia Chrzanowska-Lightowlers et al.	Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis	2002
Professor Stephen Bourke Dr Robert Bullock Emeritus Professor John Gibson Professor Pamela Shaw	Non-invasive ventilation in motor neuron disease: Current UK practice	2002
Professor Stephen Bourke Professor Pamela Shaw Dr Timothy Williams	Non-invasive ventilation in motor neuron disease: Current UK practice	2002
Professor Stephen Bourke Professor Pamela Shaw Dr Robert Bullock	Responsiveness of quality of life instruments and domains to non-invasive ventilation in motor neuron disease	2002
Steven Banner Dr Anne Fray Dr Mark Cookson Professor Pamela Shaw	The expression of the glutamate re-uptake transporter excitatory amino acid transporter 1 (EAAT1) in the normal human CNS and in motor neurone disease: An immunohistochemical study	2002
Dr Rebecca Williams Dr Mark Cookson Dr Anne Fray Dr Philip Manning Fiona Menzies et al.	Cultured glial cells are resistant to the effects of motor neurone disease-associated SOD1 mutations	2001
Professor Stephen Bourke Professor Pamela Shaw	Daytime predictors of nocturnal desaturation in motor neurone disease	2001
Dr Janet Lindsey Dr Meryl Lusher Emerita Professor Katherine Bushby Professor Pamela Shaw	Genotype-phenotype correlation in hereditary spastic paraparesis	2001
Dr Mark Cookson Professor Pamela Shaw	Glial cells of the spinal cord and subcortical white matter up-regulate neuronal nitric oxide synthase in sporadic amyotrophic lateral sclerosis	2001
Dr Anne Fray Susan Dempster Dr Rebecca Williams Dr Mark Cookson Professor Pamela Shaw et al.	Glutamine synthetase activity and expression are not affected by the development of motor neuronopathy in the G93A SOD-1/ALS mouse	2001
Dr Meryl Lusher Dr Janet Lindsey Emeritus Professor Doug Turnbull Emerita Professor Katherine Bushby Professor Pamela Shaw et al.	Paraplegin gene analysis in hereditary spastic paraparesis (HSP) pedigrees in northeast England.	2001
Professor Stephen Bourke Professor Pamela Shaw Emeritus Professor John Gibson	Respiratory function vs sleep-disordered breathing as predictors of QOL in ALS	2001
Dr Philip Manning Dr Mark Cookson Emeritus Professor Calum McNeil Professor Pamela Shaw	Superoxide-induced nitric oxide release from cultured glial cells	2001
Dr Peter Tilley Professor Pamela Shaw	Brown-Vialetto-Van Laere syndrome: Case report and literature review	2000
Dr Kathleen White Dr Meryl Lusher Dr Janet Lindsey Professor Pamela Shaw Emerita Professor Katherine Bushby et al.	Clinical and pathologic findings in hereditary spastic paraparesis with spastin mutation	2000
Professor Christopher Eggett Dr Stephen Crosier Dr Philip Manning Fiona Menzies Emeritus Professor Calum McNeil et al.	Development and characterisation of a glutamate-sensitive motor neurone cell line	2000
Professor Pamela Shaw	Expression of nitric oxide synthase isoforms in spinal cord in amyotrophic lateral sclerosis	2000
Dr Kathleen White Emerita Professor Katherine Bushby Professor Pamela Shaw	Hereditary spastic paraparesis: a review of new developments	2000
Professor Pamela Shaw Professor Christopher Eggett	Molecular factors underlying selective vulnerability of motor neurons to neurodegeneration in amyotrophic lateral sclerosis	2000
Dr Janet Lindsey Dr Meryl Lusher Dr Kathleen White Dr Rumaisa Bashir Professor Pamela Shaw et al.	Mutation analysis of the spastin gene (SPG4) in patients with hereditary spastic paraparesis	2000
Dr Philip Manning Dr Mark Cookson Professor Christopher Eggett Professor Pamela Shaw Emeritus Professor Calum McNeil et al.	Real-time bioelectrochemical investigation of brain injury and neurodegeneration	2000
Dr Philip Manning Dr Mark Cookson Professor Christopher Eggett Professor Anthony Thody Professor Pamela Shaw et al.	Real-time measurement of free radical production using specific electrochemical sensors: New insight into the consequences of O2/- and NO flux	2000
Professor Pamela Shaw	Relapsing ischemic encephaloenteropathy and cryoglobulinemia	2000
Dr Janine Tomkins Susan Dempster Steven Banner Dr Mark Cookson Professor Pamela Shaw et al.	Screening of AP endonuclease as a candidate gene for amyotrophic lateral sclerosis (ALS)	2000
Dr Louise VB Anderson Ruth Harrison Dr Robert Pogue Dr Elizabeth Vafiadaki Jennifer Moss et al.	Secondary reduction in calpain 3 expression in patients with limb girdle muscular dystrophy type 2B and Miyoshi myopathy (primary dysferlinopathies)	2000
Professor Pamela Shaw Dr Rebecca Williams	Serum and cerebrospinal fluid biochemical markers of ALS	2000
Professor Pamela Shaw	A career in academic medicine: personal experiences	1999
Professor Pamela Shaw	Calcium, glutamate, and amyotrophic lateral sclerosis: More evidence but no certainties	1999
Professor Pamela Shaw Janet Slade Professor Christopher Eggett	Low expression of GluR2 AMPA receptor subunit protein by human motor neurons	1999
Dr Gillian Borthwick Dr Margaret Johnson Professor Pamela Shaw Emeritus Professor Doug Turnbull	Mitochondrial enzyme activity in amyotrophic lateral sclerosis: Implications for the role of mitochondria in neuronal cell death	1999
Dr Mark Cookson Professor Pamela Shaw	Oxidative stress and motor neurone disease	1999
Dr Mark Cookson Professor Pamela Shaw	Poly(ADP-ribose) polymerase is found in both the nucleus and cytoplasm of human CNS neurons	1999
Professor Pamela Shaw	Relapsing ischaemic encephalo-enteropathy in cryoglobulinaemia	1999
Professor Pamela Shaw	Science, medicine, and the future - Motor neurone disease	1999
Professor Pamela Shaw	Stiff-man syndrome and its variants	1999
Dr Thomas Meyer Dr Anne Fray Professor Pamela Shaw	The RNA of the glutamate transporter EAAT2 is variably spliced in amyotrophic lateral sclerosis and normal individuals	1999
Mary Johnson Emeritus Professor Elaine Perry Professor Pamela Shaw Emeritus Professor Robert Perry	Autoradiographic comparison of the distribution of [³H]MK801 and [³H]CNQX in the human cerebellum during development and aging	1993
Emeritus Professor Elaine Perry Dr Janet Kerwin Dr Margaret Piggott Dr Jennifer Court Professor Pamela Shaw et al.	Convergent cholinergic activities in aging and Alzheimer's disease	1992