Publications by Professor David Lydall - ePrints

Browsing publications by Professor David Lydall.

Newcastle Authors	Title	Year
Dr Andrew Banks Professor David Lydall	Checkpoint inhibition of origin firing prevents DNA topological stress	2019
Professor David Lydall	Cis and trans interactions between genes encoding PAF1 complex and ESCRT machinery components in yeast	2018
Dr Marta Markiewicz-Potoczny Professor David Lydall	A critical role for Dna2 at unwound telomeres	2018
Dr Eva-Maria Holstein Dr Conor Lawless Dr Andrew Banks Professor David Lydall	Genome-wide Quantitative Fitness Analysis (QFA) of yeast cultures	2018
Victoria Torrance Professor David Lydall	Overlapping open reading frames strongly reduce human and yeast STN1 gene expression and affect telomere function	2018
Professor David Lydall	Paf1 and Ctr9, core components of the PAF1 complex, maintain low levels of telomeric repeat containing RNA	2018
Dr Andrew Banks Dr Conor Lawless Professor David Lydall	The contribution of non-essential Schizosaccharomyces pombe genes to fitness in response to altered nutrient supply and target of rapamycin activity	2018
Dr Andrew Banks Professor David Lydall	Vps74 connects the golgi apparatus and telomeres in Saccharomyces cerevisiae	2018
Adam Ciesiolka Dr Conor Lawless Professor David Lydall	A Functional Link Between Bir1 and the Saccharomyces cerevisiae Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis	2017
Dr Eva-Maria Holstein Dr Conor Lawless Dr Andrew Banks Professor Darren Wilkinson Professor David Lydall et al.	Systematic Analysis of the DNA Damage Response Network in Telomere Defective Budding Yeast	2017
Jonathan Heydari Dr Conor Lawless Professor David Lydall Professor Darren Wilkinson	Bayesian hierarchical modelling for inferring genetic interactions in yeast	2016
Marta Markiewicz-Potoczny Professor David Lydall	Costs, benefits and redundant mechanisms of adaption to chronic low-dose stress in yeast	2016
Melanie Ikeh Dr Alison Day Dr Emma Tarrant Dr Kevin Waldron Dr Andrew Banks et al.	Pho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasis	2016
Yuan Xue Dr Iglika Ivanova Professor David Lydall Dr Laura Maringele	Rif1 and Exo1 regulate the genomic instability following telomere losses	2016
Dr Marion Dubarry Dr Conor Lawless Dr Andrew Banks Dr Simon Cockell Professor David Lydall et al.	Genetic Networks Required to Coordinate Chromosome Replication by DNA Polymerases α, δ, and ε in Saccharomyces cerevisiae	2015
Dr Siddharth Narayanan Dr Marion Dubarry Dr Conor Lawless Dr Andrew Banks Professor Darren Wilkinson et al.	Quantitative Fitness Analysis Identifies exo1∆ and Other Suppressors or Enhancers of Telomere Defects in Schizosaccharomyces pombe	2015
Dr Greg Ngo Professor David Lydall	The 9-1-1 checkpoint clamp coordinates resection at DNA double strand breaks	2015
Matthew Greetham Professor David Lydall Professor Bernard Connolly	The Telomere Binding Protein Cdc13 and the Single-Stranded DNA Binding Protein RPA Protect Telomeric DNA from Resection by Exonucleases	2015
Jonathan Heydari Dr Conor Lawless Professor David Lydall Professor Darren Wilkinson	Fast Bayesian parameter estimation for stochastic logistic growth models	2014
Dr Eva-Maria Holstein Kate Clark Professor David Lydall	Interplay between Nonsense-Mediated mRNA Decay and DNA Damage Response Pathways Reveals that Stn1 and Ten1 Are the Key CST Telomere-Cap Components	2014
Dr Greg Ngo Dr Marion Dubarry Professor David Lydall	The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo1	2014
Lizzy Andrew Dr Stephanie Merchan Dr Conor Lawless Dr Andrew Banks Professor Darren Wilkinson et al.	Pentose Phosphate Pathway Function Affects Tolerance to the G-Quadruplex Binder TMPyP4	2013
Kangzhen Dong Dr Stephen Addinall Professor David Lydall Dr Julian Rutherford	The Yeast Copper Response Is Regulated by DNA Damage	2013
Dr Andrew Banks Dr Conor Lawless Professor David Lydall	A Quantitative Fitness Analysis Workflow	2012
James Dewar Professor David Lydall	Similarities and differences between "uncapped" telomeres and DNA double-strand breaks	2012
Jochen Weile Dr Matthew Pocock Dr Simon Cockell Dr Phillip Lord James Dewar et al.	Customizable views on semantically integrated networks for systems biology	2011
Dr Hsin Yu Chang Dr Conor Lawless Dr Stephen Addinall Morgan Taschuk Professor Anil Wipat et al.	Genome-Wide Analysis to Identify Pathways Affecting Telomere-Initiated Senescence in Budding Yeast	2011
Dr Stephen Addinall Dr Eva-Maria Holstein Dr Conor Lawless Dr Min Yu Dr Kaye Chapman et al.	Quantitative Fitness Analysis Shows That NMD Proteins and Many Other Protein Complexes Suppress or Enhance Distinct Telomere Cap Defects	2011
Dr Conor Lawless Professor Darren Wilkinson Dr Stephen Addinall Professor David Lydall	Colonyzer: automated quantification of micro-organism growth characteristics on solid agar	2010
James Dewar Professor David Lydall	Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping	2010
Dr Greg Ngo Professor David Lydall	Survival and Growth of Yeast without Telomere Capping by Cdc13 in the Absence of Sgs1, Exo1, and Rad9	2010
James Dewar Professor David Lydall	Telomere Replication: Mre11 Leads the Way	2010
Dr Jennifer Hallinan Dr Matthew Pocock Dr Stephen Addinall Professor David Lydall Professor Anil Wipat et al.	Clustering incorporating shortest paths identifies relevant modules in functional interaction networks	2009
Professor David Lydall	Taming the tiger by the tail: modulation of DNA damage responses by telomeres	2009
Professor David Lydall Dr Laura Maringele	Telomere Maintenance and Survival in Saccharomyces cerevisiae in the Absence of Telomerase and RAD52	2009
Dr Amanda Greenall Dr Daniel Swan Dr Heiko Peters Professor Anil Wipat Professor Darren Wilkinson et al.	A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD(+) biosynthetic gene BNA2 in chromosome end protection	2008
Dr Stephen Addinall Dawn Downey Dr Min Yu Dr Mikhajlo Zubko James Dewar et al.	A Genome-wide Suppressor and Enhancer Analysis of cdc13-1 Reveals Varied Cellular Processes Influencing Telomere Capping in Saccharomyces cerevisiae	2008
Dr Isabelle Morin Dr Greg Ngo Dr Amanda Greenall Dr Mikhajlo Zubko Professor David Lydall et al.	Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response	2008
Dr Vasileia Sapountzi Professor David Lydall	Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres	2008
Dr Vasileia Sapountzi Dr Amanda Greenall Professor David Lydall	The SAS2 histone acetyltransferase is important for the telomere uncapping response	2008
Dr Carole Proctor Professor David Lydall Professor Richard Boys Dr Colin Gillespie Dr Daryl Shanley et al.	Modelling the checkpoint response to telomere uncapping in budding yeast	2007
Professor David Lydall	Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1	2007
Dr Laura Maringele Dr Mikhajlo Zubko Professor David Lydall	A Genome-Wide Screen Identifies the Evolutionarily Conserved KEOPS Complex as a Telomere Regulator	2006
Dr Mikhajlo Zubko Dr Laura Maringele Steven Foster Professor David Lydall	Detecting repair intermediates in vivo: Effects of DNA damage response genes on single-stranded DNA accumulation at uncapped telomeres in budding yeast	2006
Dr Mikhajlo Zubko Professor David Lydall	Linear chromosome maintenance in the absence of essential telomere-capping proteins	2006
Steven Foster Dr Mikhajlo Zubko Professor David Lydall	MRX protects telomeric DNA at uncapped telomeres of budding yeast cdc13-1 mutants	2006
Professor David Lydall Dr Simon Whitehall	Chromatin and the DNA damage response	2005
Dr Laura Maringele Professor David Lydall	Pulsed Field Gel Electrophoresis of Budding Yeast Chromosomes	2005
Dr Laura Maringele Professor David Lydall	The PAL-mechanism of Chromosome Maintenance: Causes and Consequences	2005
Professor David Lydall	A domain of Rad9 specifically required for activation of Chk1 in budding yeast	2004
Professor David Lydall	Exo1 and Rad24 differentially regulate generation of ssDNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants	2004
Dr Laura Maringele Professor David Lydall	EXO1 Plays a Role in Generating Type I and Type II Survivors in Budding Yeast	2004
Professor David Lydall	Mec1 and Rad53 Inhibit Formation of Single-Stranded DNA at Telomeres of Saccharomyces cerevisiae cdc13-1 Mutants	2004
Dr Laura Maringele Professor David Lydall	Telomerase- and recombination-independent immortalization of budding yeast	2004
Professor David Lydall	Hiding at the ends of yeast chromosomes: telomeres, nucleases and checkpoint pathways	2003
Dr Laura Maringele Professor David Lydall	EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Δ mutants	2002
Chloe Booth Professor David Lydall	Quantitative amplification of single-stranded DNA (QAOS) demonstrates that cdc13-1 mutants generate ssDNA in a telomere to centromere direction	2001
Professor David Lydall	Checkpoint proteins and the metabolism of DNA damage	2000
Professor David Lydall	NDD1, a high-dosage suppressor of cdc28-1N, is essential for expression of a subset of late-S-phase-specific genes in Saccharomyces cerevisiae	1999