Dr Santu Saha Dr Stuart Rundle Dr Ioannis Kotsopoulos Dr Jake Begbie Rachel Howarth et al. | Determining the Potential of DNA Damage Response (DDR) Inhibitors in Cervical Cancer Therapy | 2022 |
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Professor Kevin Marchbank Dr Isabel Pappworth Harriet Denton Kate Cooke Grant Richardson et al. | C3 Glomerulopathy and Related Disorders in Children. | 2021 |
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Dr Ola Kamala Dr Thomas Hallam Tom Cox Dr Yi Yang Dr Falguni Vyas et al. | Homodimeric Minimal Factor H: In Vivo Tracking and Extended Dosing Studies in Factor H Deficient Mice | 2021 |
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Dr Yi Yang Dr Isabel Pappworth Holly Denton Professor Kevin Marchbank
| Murine Factor H Co-Produced in Yeast With Protein Disulfide Isomerase Ameliorated C3 Dysregulation in Factor H-Deficient Mice | 2021 |
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Dr Santu Saha Rachel Howarth Dr Isabel Pappworth Lucy Gentles Professor Kevin Marchbank et al. | Exploring rucaparib as chemo-radiosensitiser to increase therapeutic ratio in cervical cancer. | 2020 |
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Dr Santu Saha Rachel Howarth Dr Isabel Pappworth Professor Kevin Marchbank Professor Nicola Curtin et al. | Potential use of the PARP inhibitor rucaparib to enhance cervical cancer treatment. | 2020 |
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Dr Isabel Pappworth
| Selectivity of C3-opsonin targeted complement inhibitors: a distinct advantage in the protection of erythrocytes from paroxysmal nocturnal hemoglobinuria patients | 2016 |
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Dr Isabel Pappworth Dr Edwin Wong Professor Neil Sheerin Professor Kevin Marchbank
| An extended mini-complement factor H molecule ameliorates experimental C3 glomerulopathy | 2015 |
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Rachael Horbury Dr Karim Bennaceur Catriona Barker Professor David Kavanagh Professor Tim Goodship et al. | Autoantibodies to CD59, CD55, CD46 or CD35 are not associated with atypical haemolytic uraemic syndrome (aHUS) | 2015 |
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Dr Edwin Wong Dr Jeremy Palmer Professor Neil Sheerin Dr Isabel Pappworth
| FH1-5(18-20) ameliorates experimental C3 glomerulopathy; generation and testing of a murine version for further pre-clinical experiments | 2015 |
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Dr Edwin Wong Dr Isabel Pappworth Professor Claire Harris Professor Tim Goodship Dr Sally Johnson et al. | The national study of membranoproliferative glomerulonephrtis and C3 glomerulopathy - characterisation of the paediatric cohort | 2015 |
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Catriona Barker Professor David Kavanagh Professor Tim Goodship Dr Isabel Pappworth
| Autoantibodies to CD59, CD55, CD46 and CD35 are not associated with aHUS | 2014 |
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Professor Tim Goodship Dr Isabel Pappworth Dr Iain Moore Dr Eva-Maria Hunze James Staniforth et al. | Factor H autoantibodies in membranoproliferative glomerulonephritis | 2012 |
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Professor David Kavanagh Dr Isabel Pappworth Christine Hayes Dr Iain Moore Dr Eva-Maria Hunze et al. | Factor I Autoantibodies in Patients with Atypical Hemolytic Uremic Syndrome: Disease-Associated or an Epiphenomenon? | 2012 |
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Dr Iain Moore Dr Lisa Turnbull Dr Isabel Pappworth Professor David Kavanagh James Staniforth et al. | Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome | 2010 |
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Dr Isabel Pappworth Dr Iain Moore Dr Lisa Turnbull Professor David Kavanagh James Staniforth et al. | Complement Factor H Autoantibodies and Age-Related Macular Degeneration | 2010 |
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Dr Isabel Pappworth Professor David Kavanagh Dr Iain Moore Dr Lisa Turnbull
| Factor H autoantibodies are associated with MPGN | 2010 |
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Professor David Kavanagh Dr Isabel Pappworth Dr John Tapson Dr Iain Moore Dr Lisa Turnbull et al. | Factor I autoantibodies are associated with atypical haemolytic uraemic syndrome | 2010 |
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Dr Isabel Pappworth Professor Kevin Marchbank Dr Lisa Turnbull Professor Tim Goodship
| Successful Renal Transplantation in Factor H Autoantibody Associated HUS with CFHR1 and 3 Deficiency and CFH Variant G2850T | 2010 |
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Dr Isabel Pappworth Christine Hayes Dr Andrew Knight Professor Kevin Marchbank
| The role of complement in the formation of B regulatory cells | 2010 |
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Dr Isabel Pappworth Professor Kevin Marchbank
| Defective B cell ontogeny and humoral immune response in mice prematurely expressing human complement receptor 2 (CR2, CD21) is similar to that seen in aging wild type mice | 2009 |
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Dr Isabel Pappworth Professor Kevin Marchbank
| Increased B cell deletion and significantly reduced auto-antibody titre due to premature expression of human complement receptor 2 (CR2, CD21) | 2009 |
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Dr Isabel Pappworth Professor Kevin Marchbank
| Normal B cell ontogeny in mice expressing human complement receptor type 1 under the control of a lambda light chain promoter enhancer | 2007 |
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