Publications by Dr Isabel Pappworth - ePrints

Browsing publications by Dr Isabel Pappworth.

Newcastle Authors	Title	Year
Dr Kate Smith-Jackson Dr Patrick Walsh Dr Gemma Thompson Dr Beth Gibson Chloe Connelly et al.	The membrane attack complex drives the thrombotic microangiopathy in complement mediated aHUS.	2024
Dr Santu Saha Dr Stuart Rundle Dr Ioannis Kotsopoulos Dr Jake Begbie Rachel Howarth et al.	Determining the Potential of DNA Damage Response (DDR) Inhibitors in Cervical Cancer Therapy	2022
Professor Kevin Marchbank Dr Isabel Pappworth Harriet Denton Kate Cooke Grant Richardson et al.	C3 Glomerulopathy and Related Disorders in Children.	2021
Dr Ola Kamala Dr Thomas Hallam Tom Cox Dr Yi Yang Dr Falguni Vyas et al.	Homodimeric Minimal Factor H: In Vivo Tracking and Extended Dosing Studies in Factor H Deficient Mice	2021
Dr Yi Yang Dr Isabel Pappworth Holly Denton Professor Kevin Marchbank	Murine Factor H Co-Produced in Yeast With Protein Disulfide Isomerase Ameliorated C3 Dysregulation in Factor H-Deficient Mice	2021
Dr Santu Saha Rachel Howarth Dr Isabel Pappworth Lucy Gentles Professor Kevin Marchbank et al.	Exploring rucaparib as chemo-radiosensitiser to increase therapeutic ratio in cervical cancer.	2020
Dr Santu Saha Rachel Howarth Dr Isabel Pappworth Professor Kevin Marchbank Professor Nicola Curtin et al.	Potential use of the PARP inhibitor rucaparib to enhance cervical cancer treatment.	2020
Dr Isabel Pappworth	Selectivity of C3-opsonin targeted complement inhibitors: a distinct advantage in the protection of erythrocytes from paroxysmal nocturnal hemoglobinuria patients	2016
Dr Isabel Pappworth Dr Edwin Wong Professor Neil Sheerin Professor Kevin Marchbank	An extended mini-complement factor H molecule ameliorates experimental C3 glomerulopathy	2015
Rachael Horbury Dr Karim Bennaceur Catriona Barker Professor David Kavanagh Professor Tim Goodship et al.	Autoantibodies to CD59, CD55, CD46 or CD35 are not associated with atypical haemolytic uraemic syndrome (aHUS)	2015
Dr Edwin Wong Dr Jeremy Palmer Professor Neil Sheerin Dr Isabel Pappworth	FH1-5^(18-20) ameliorates experimental C3 glomerulopathy; generation and testing of a murine version for further pre-clinical experiments	2015
Dr Edwin Wong Dr Isabel Pappworth Professor Claire Harris Professor Tim Goodship Dr Sally Johnson et al.	The national study of membranoproliferative glomerulonephrtis and C3 glomerulopathy - characterisation of the paediatric cohort	2015
Catriona Barker Professor David Kavanagh Professor Tim Goodship Dr Isabel Pappworth	Autoantibodies to CD59, CD55, CD46 and CD35 are not associated with aHUS	2014
Professor Tim Goodship Dr Isabel Pappworth Dr Iain Moore Dr Eva-Maria Hunze James Staniforth et al.	Factor H autoantibodies in membranoproliferative glomerulonephritis	2012
Professor David Kavanagh Dr Isabel Pappworth Christine Hayes Dr Iain Moore Dr Eva-Maria Hunze et al.	Factor I Autoantibodies in Patients with Atypical Hemolytic Uremic Syndrome: Disease-Associated or an Epiphenomenon?	2012
Dr Iain Moore Dr Lisa Turnbull Dr Isabel Pappworth Professor David Kavanagh James Staniforth et al.	Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome	2010
Dr Isabel Pappworth Dr Iain Moore Dr Lisa Turnbull Professor David Kavanagh James Staniforth et al.	Complement Factor H Autoantibodies and Age-Related Macular Degeneration	2010
Dr Isabel Pappworth Professor David Kavanagh Dr Iain Moore Dr Lisa Turnbull	Factor H autoantibodies are associated with MPGN	2010
Professor David Kavanagh Dr Isabel Pappworth Dr John Tapson Dr Iain Moore Dr Lisa Turnbull et al.	Factor I autoantibodies are associated with atypical haemolytic uraemic syndrome	2010
Dr Isabel Pappworth Professor Kevin Marchbank Dr Lisa Turnbull Professor Tim Goodship	Successful Renal Transplantation in Factor H Autoantibody Associated HUS with CFHR1 and 3 Deficiency and CFH Variant G2850T	2010
Dr Isabel Pappworth Christine Hayes Dr Andrew Knight Professor Kevin Marchbank	The role of complement in the formation of B regulatory cells	2010
Dr Isabel Pappworth Professor Kevin Marchbank	Defective B cell ontogeny and humoral immune response in mice prematurely expressing human complement receptor 2 (CR2, CD21) is similar to that seen in aging wild type mice	2009
Dr Isabel Pappworth Professor Kevin Marchbank	Increased B cell deletion and significantly reduced auto-antibody titre due to premature expression of human complement receptor 2 (CR2, CD21)	2009
Dr Isabel Pappworth Professor Kevin Marchbank	Normal B cell ontogeny in mice expressing human complement receptor type 1 under the control of a lambda light chain promoter enhancer	2007