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Browsing publications by Dr Isabel Pappworth.

Newcastle AuthorsTitleYearFull text
Dr Santu Saha
Dr Stuart Rundle
Dr Ioannis Kotsopoulos
Dr Jake Begbie
Rachel Howarth
et al.
Determining the Potential of DNA Damage Response (DDR) Inhibitors in Cervical Cancer Therapy2022
Professor Kevin Marchbank
Dr Isabel Pappworth
Harriet Denton
Kate Cooke
Grant Richardson
et al.
C3 Glomerulopathy and Related Disorders in Children.2021
Dr Ola Kamala
Dr Thomas Hallam
Tom Cox
Dr Yi Yang
Dr Falguni Vyas
et al.
Homodimeric Minimal Factor H: In Vivo Tracking and Extended Dosing Studies in Factor H Deficient Mice2021
Dr Yi Yang
Dr Isabel Pappworth
Holly Denton
Professor Kevin Marchbank
Murine Factor H Co-Produced in Yeast With Protein Disulfide Isomerase Ameliorated C3 Dysregulation in Factor H-Deficient Mice2021
Dr Santu Saha
Rachel Howarth
Dr Isabel Pappworth
Lucy Gentles
Professor Kevin Marchbank
et al.
Exploring rucaparib as chemo-radiosensitiser to increase therapeutic ratio in cervical cancer.2020
Dr Santu Saha
Rachel Howarth
Dr Isabel Pappworth
Professor Kevin Marchbank
Professor Nicola Curtin
et al.
Potential use of the PARP inhibitor rucaparib to enhance cervical cancer treatment.2020
Dr Isabel Pappworth
Selectivity of C3-opsonin targeted complement inhibitors: a distinct advantage in the protection of erythrocytes from paroxysmal nocturnal hemoglobinuria patients 2016
Dr Isabel Pappworth
Dr Edwin Wong
Professor Neil Sheerin
Professor Kevin Marchbank
An extended mini-complement factor H molecule ameliorates experimental C3 glomerulopathy2015
Rachael Horbury
Dr Karim Bennaceur
Catriona Barker
Professor David Kavanagh
Professor Tim Goodship
et al.
Autoantibodies to CD59, CD55, CD46 or CD35 are not associated with atypical haemolytic uraemic syndrome (aHUS)2015
Dr Edwin Wong
Dr Jeremy Palmer
Professor Neil Sheerin
Dr Isabel Pappworth
FH1-5(18-20) ameliorates experimental C3 glomerulopathy; generation and testing of a murine version for further pre-clinical experiments2015
Dr Edwin Wong
Dr Isabel Pappworth
Professor Claire Harris
Professor Tim Goodship
Dr Sally Johnson
et al.
The national study of membranoproliferative glomerulonephrtis and C3 glomerulopathy - characterisation of the paediatric cohort2015
Catriona Barker
Professor David Kavanagh
Professor Tim Goodship
Dr Isabel Pappworth
Autoantibodies to CD59, CD55, CD46 and CD35 are not associated with aHUS2014
Professor Tim Goodship
Dr Isabel Pappworth
Dr Iain Moore
Dr Eva-Maria Hunze
James Staniforth
et al.
Factor H autoantibodies in membranoproliferative glomerulonephritis2012
Professor David Kavanagh
Dr Isabel Pappworth
Christine Hayes
Dr Iain Moore
Dr Eva-Maria Hunze
et al.
Factor I Autoantibodies in Patients with Atypical Hemolytic Uremic Syndrome: Disease-Associated or an Epiphenomenon?2012
Dr Iain Moore
Dr Lisa Turnbull
Dr Isabel Pappworth
Professor David Kavanagh
James Staniforth
et al.
Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome2010
Dr Isabel Pappworth
Dr Iain Moore
Dr Lisa Turnbull
Professor David Kavanagh
James Staniforth
et al.
Complement Factor H Autoantibodies and Age-Related Macular Degeneration2010
Dr Isabel Pappworth
Professor David Kavanagh
Dr Iain Moore
Dr Lisa Turnbull
Factor H autoantibodies are associated with MPGN2010
Professor David Kavanagh
Dr Isabel Pappworth
Dr John Tapson
Dr Iain Moore
Dr Lisa Turnbull
et al.
Factor I autoantibodies are associated with atypical haemolytic uraemic syndrome2010
Dr Isabel Pappworth
Professor Kevin Marchbank
Dr Lisa Turnbull
Professor Tim Goodship
Successful Renal Transplantation in Factor H Autoantibody Associated HUS with CFHR1 and 3 Deficiency and CFH Variant G2850T2010
Dr Isabel Pappworth
Christine Hayes
Dr Andrew Knight
Professor Kevin Marchbank
The role of complement in the formation of B regulatory cells2010
Dr Isabel Pappworth
Professor Kevin Marchbank
Defective B cell ontogeny and humoral immune response in mice prematurely expressing human complement receptor 2 (CR2, CD21) is similar to that seen in aging wild type mice2009
Dr Isabel Pappworth
Professor Kevin Marchbank
Increased B cell deletion and significantly reduced auto-antibody titre due to premature expression of human complement receptor 2 (CR2, CD21)2009
Dr Isabel Pappworth
Professor Kevin Marchbank
Normal B cell ontogeny in mice expressing human complement receptor type 1 under the control of a lambda light chain promoter enhancer2007