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Browsing publications by Emeritus Professor Andrew Mellor.

Newcastle AuthorsTitleYearFull text
Dr Lei Huang
Emeritus Professor Andrew Mellor
Exosome-derived miR-142-5p remodels lymphatic vessels and induces IDO to promote immune privilege in the tumour microenvironment2021
Nga Vo
Dr Lei Huang
Emeritus Professor Andrew Mellor
Dr Katarina Novakovic
Genipin‐crosslinked chitosan hydrogels: Preliminary evaluation of the in vitro biocompatibility and biodegradation2021
Dr Lei Huang
Emeritus Professor Andrew Mellor
Indoleamine 2,3 dioxygenase, age, and immune activation in people living with HIV2021
Dr Emily Thompson
Lucy Bates
Dr Ibrahim Ibrahim
Dr Avinash Sewpaul
Rodrigo Figueiredo
et al.
Novel delivery of cellular therapy to reduce ischaemia reperfusion injury in kidney transplantation2021
Dr Nicola Maney
Dr Ben Barron-Millar
Dr Christopher Carey
Ian Herron
Dr Amy Anderson
et al.
Pim Kinases as Therapeutic Targets in Early Rheumatoid Arthritis2021
Dr Lei Huang
Emeritus Professor Andrew Mellor
STING Negatively Regulates Allogeneic T-Cell Responses by Constraining Antigen-Presenting Cell Function2021
Dr Daniel Lin
Dr Lei Huang
James O'Hara
Emerita Professor Janet Wilson
Emeritus Professor Andrew Mellor
et al.
The immunotherapeutic role of indoleamine 2,3-dioxygenase in head and neck squamous cell carcinoma: A systematic review2021
Dr Lei Huang
Emeritus Professor Andrew Mellor
A Validation Study on IDO Immune Biomarkers for Survival Prediction in Non–Small Cell Lung Cancer: Radiation Dose Fractionation Effect in Early-Stage Disease2020
Dr Lei Huang
Emeritus Professor Andrew Mellor
CD40 Accelerates the Antigen-Specific Stem-Like Memory CD8+ T Cells Formation and Human Papilloma Virus (HPV)-Positive Tumor Eradication2020
Dr Lei Huang
Emeritus Professor Andrew Mellor
CD73 on cancer-associated fibroblasts enhanced by the A2B-mediated feedforward circuit enforces an immune checkpoint2020
Dr Henrique De Paula Lemos
Dr Rong Ou
Dr Caroline McCardle
Dr Lei Huang
Emeritus Professor Andrew Mellor
et al.
Co-treatments to boost IDO activity and inhibit production of downstream catabolites induce durable suppression of Experimental Autoimmune Encephalomyelitis2020
Dr Rong Ou
Dr Caroline McCardle
Jack Minett
Dr Lei Huang
Emeritus Professor Andrew Mellor
et al.
Overcoming resistance to STING agonist therapy to incite durable protective antitumor immunity2020
Nga Vo
Dr Lei Huang
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Dr Katarina Novakovic
et al.
Poly(ethylene glycol)‐interpenetrated genipin‐crosslinked chitosan hydrogels: Structure, pH responsiveness, gelation kinetics, and rheology2020
Dr Lei Huang
Emeritus Professor Andrew Mellor
Adoptive CD8+ T cell therapy against cancer:Challenges and opportunities 2019
Dr Henrique De Paula Lemos
Dr Lei Huang
Emeritus Professor Andrew Mellor
Immune control by amino acid catabolism during tumorigenesis and therapy2019
Dr Lei Huang
Emeritus Professor Andrew Mellor
Limited effect of indolamine 2,3-dioxygenase expression and enzymatic activity on lupus-like disease in b6.Nba2 mice2019
Emeritus Professor Andrew Mellor
Dr Lei Huang
Metabolic requirements for expanding and arming a clone army2019
Nga Vo
Dr Lei Huang
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Dr Katarina Novakovic
et al.
Smart chitosan-based hydrogels for targeted drug delivery applications2019
Dr Henrique De Paula Lemos
Dr Lei Huang
Dr Rong Ou
Emeritus Professor Andrew Mellor
Stimulator of Interferon Genes Agonists attenuate type I diabetes progression in NOD mice2019
Dr Lei Huang
Emeritus Professor Andrew Mellor
IDO Immune Status after Chemoradiation May Predict Survival in Lung Cancer Patients2018
Nga Vo
Dr Lei Huang
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Dr Katarina Novakovic
et al.
Smart chitosan-based hydrogels for targeted drug delivery application2018
Dr Henrique De Paula Lemos
Dr Lei Huang
Emeritus Professor Andrew Mellor
Carbidopa, a drug in use for management of Parkinson disease inhibits T cell activation and autoimmunity2017
Emeritus Professor Andrew Mellor
Dr Henrique De Paula Lemos
Dr Lei Huang
Indoleamine 2,3-Dioxygenase and tolerance: Where Are We Now?2017
Emeritus Professor Andrew Mellor
Dr Henrique De Paula Lemos
Dr Lei Huang
Indoleamine 2,3-Dioxygenase and Tolerance: Where Are We Now?2017
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Soluble CD83 Inhibits T Cell Activation by Binding to the TLR4/MD-2 Complex on CD14+ Monocytes2017
Dr Lei Huang
Emeritus Professor Andrew Mellor
An essential role of Ffar2 (Gpr43) in dietary fibre-mediated promotion of healthy composition of gut microbiota and suppression of intestinal carcinogenesis2016
Emeritus Professor Andrew Mellor
IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance2016
Dr Henrique De Paula Lemos
Dr Lei Huang
Dr Rong Ou
Emeritus Professor Andrew Mellor
STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation2016
Dr Lei Huang
Dr Rong Ou
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase2016
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Alkylating Agent Melphalan Augments the Efficacy of Adoptive Immunotherapy Using Tumor-Specific CD4+ T Cells2015
Emeritus Professor Andrew Mellor
Canonical Wnt Signaling in Dendritic Cells Regulates Th1/Th17 Responses and Suppresses Autoimmune Neuroinflammation2015
Emeritus Professor Andrew Mellor
IFN regulatory factor 8 represses GM-CSF expression in T cells to affect myeloid cell lineage differentiation.2015
Dr Henrique De Paula Lemos
Dr Lei Huang
Emeritus Professor Andrew Mellor
STING, nanoparticles, autoimmune disease and cancer: a novel paradigm for immunotherapy?2015
Dr Lei Huang
Emeritus Professor Andrew Mellor
The PTEN pathway in Tregs is a critical driver for the suppressive tumor microenvironment2015
Emeritus Professor Andrew Mellor
β-catenin promotes regulatory T-cell responses in tumors by inducing vitamin A metabolism in dendritic cells2015
Dr Henrique De Paula Lemos
Dr Lei Huang
Emeritus Professor Andrew Mellor
Activation of the STING Adaptor Attenuates Experimental Autoimmune Encephalitis.2014
Dr Henrique De Paula Lemos
Dr Lei Huang
Emeritus Professor Andrew Mellor
Cytosolic DNA sensing via the stimulator of interferon genes adaptor: Yin and Yang of immune responses to DNA2014
Emeritus Professor Andrew Mellor
GCN2-dependent metabolic stress is essential for endotoxemic cytokine induction and pathology2014
Emeritus Professor Andrew Mellor
IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation2014
Dr Henrique De Paula Lemos
Dr Lei Huang
Emeritus Professor Andrew Mellor
Immunosuppressive Myeloid Cells Induced by Chemotherapy Attenuate Antitumor CD4+ T-Cell Responses through the PD-1-PD-L1 Axis2014
Emeritus Professor Andrew Mellor
Indoleamine 2,3-dioxygenase (IDO) activity during the primary immune response to influenza infection modifies the memory T cell response to influenza challenge2014
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Marginal zone CD169+ macrophages coordinate apoptotic cell-driven cellular recruitment and tolerance2014
Dr Lei Huang
Emeritus Professor Andrew Mellor
Metabolic control of tumour progression and antitumour immunity.2014
Emeritus Professor Andrew Mellor
T cell costimulation molecules CD80/86 inhibit osteoclast differentiation by inducing the IDO/tryptophan pathway2014
Emeritus Professor Andrew Mellor
The indoleamine 2,3-dioxygenase pathway controls complement-dependent enhancement of chemo-radiation therapy against murine glioblastoma2014
Emeritus Professor Andrew Mellor
TLR2-dependent activation of β-catenin pathway in dendritic cells induces regulatory responses and attenuates autoimmune inflammation2014
Dr Henrique De Paula Lemos
Fan Pan
Emeritus Professor Andrew Mellor
An Inherently Bifunctional Subset of Foxp3+ T Helper Cells is Controlled by the Transcription Factor Eos2013
Emeritus Professor Andrew Mellor
B7h (ICOS-L) maintains tolerance at the fetomaternal interface2013
Dr Lei Huang
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Cutting Edge: DNA Sensing via the STING Adaptor in Myeloid Dendritic Cells Induces Potent Tolerogenic Responses2013
Emeritus Professor Andrew Mellor
Indoleamine 2,3-Dioxygenase 1 (Ido1) Is Involved in the Control of Mouse Caput Epididymis Immune Environment2013
Dr Lei Huang
Emeritus Professor Andrew Mellor
Induction and role of indoleamine 2,3 dioxygenase in mouse models of influenza a virus infection2013
Dr Lei Huang
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Altered tryptophan metabolism as a paradigm for good and bad aspects of immune privilege in chronic inflammatory diseases2012
Dr Lei Huang
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Amino acid catabolism: a pivotal regulator of innate and adaptive immunity2012
Dr Lei Huang
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Engineering DNA Nanoparticles as Immunomodulatory Reagents that Activate Regulatory T Cells2012
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Leishmania major Attenuates Host Immunity by Stimulating Local Indoleamine 2,3-Dioxygenase Expression2011
Emeritus Professor Andrew Mellor
B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase2010
Emeritus Professor Andrew Mellor
Reprogrammed Foxp3+ Regulatory T Cells Provide Essential Help to Support Cross-presentation and CD8+ T Cell Priming in Naive Mice2010
Emeritus Professor Andrew Mellor
IDO activates regulatory T cells and blocks their conversion into Th17-like T cells2009
Emeritus Professor Andrew Mellor
Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase2008