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Browsing publications by Dr Andrew Hughes.

Newcastle AuthorsTitleYearFull text
Dr Christopher Jones
Dr Andrew Hughes
Prophylactic cranial irradiation (PCI) in extensive stage small cell lung cancer (ED-SCLC): a retrospective review of practice at the Northern Centre for Cancer Treatment2009
Dr Ashraf Azzabi
Dr Andrew Hughes
Dr Paula Calvert
Professor Ruth Plummer
Melanie Griffin
et al.
Phase I study of temozolomide plus paclitaxel in patients with advanced malignant melanoma and associated in vitro investigations2005
Professor Alan Boddy
Gordon Taylor
Dr Andrew Hughes
Professor Alan Calvert
Professor Herbie Newell
et al.
2-[11C]thymidine positron emission tomography as an indicator of thymidylate synthase inhibition in patients treated with AG3372003
Professor Ruth Plummer
Dr Andrew Hughes
Dr Martin Highley
Dr Sathyarathna Gokul
Professor Alan Calvert
et al.
A phase I trial of ZD9331, a water-soluble, nonpolyglutamatable, thymidylate synthase inhibitor2003
Simon Cox
Andrew Critchley
Dr Andrew Hughes
Faye Kemp
Dr Iain McNab
et al.
Coaxial ion beam/infrared laser beam spectrometer for investigating infrared spectra of doubly positively charged molecules (molecular dications)2002
Dr Andrew Hughes
Dr Paula Calvert
Dr Ashraf Azzabi
Professor Ruth Plummer
Melanie Griffin
et al.
Phase I clinical and pharmacokinetic study of pemetrexed and carboplatin in patients with malignant pleural mesothelioma2002
Dr Andrew Hughes
Dr Ashraf Azzabi
Professor Ruth Plummer
Dr Jane Margetts
Kevin Fishwick
et al.
A phase I dose escalation study of doxorubicin in combination with pemetrexed (Alimta (R), multitargeted antifolate).2001
Professor Nicola Curtin
Dr Andrew Hughes
Pemetrexed disodium, a novel antifolate with multiple targets2001
Dr Paula Calvert
Dr Ashraf Azzabi
Dr Andrew Hughes
Professor Ruth Plummer
Angela Robinson
et al.
A phase I clinical and pharmacokinetic study of EPO906 (epothilone B) in patients with advanced solid tumours.2000
Dr Andrew Hughes
Melanie Griffin
Professor Herbie Newell
Professor Alan Calvert
Professor Alan Boddy
et al.
Clinical pharmacokinetic and in vitro combination studies of nolatrexed dihydrochloride (AG337, Thymitaq(TM)) and paclitaxel2000
Dr Andrew Hughes
Professor Alan Calvert
An update on thymidylate synthase inhibitors1999
Dr Andrew Hughes
Melanie Griffin
Professor Alan Calvert
Professor Herbie Newell
Professor Alan Boddy
et al.
Phase I studies with the nonclassical antifolate nolatrexed dihydrochloride (AG337, THYMITAQ) administered orally for 5 days1999
Dr Andrew Hughes
Melanie Griffin
Professor Alan Calvert
Andrew Johnston
Professor Herbie Newell
et al.
Pharmacokinetic interactions in a phase I study of nolatrexed (AG337, THYMITAQ TM) and paclitaxel in patients with advanced solid tumours1998
Professor Alan Calvert
Professor Alan Boddy
Dr Andrew Hughes
Lynsey Robson
Huw Thomas
et al.
Carboplatin in combination with paclitaxel in advanced ovarian cancer: dose determination and pharmacokinetic and pharmacodynamic interactions.1995