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Browsing publications by Gordon Taylor.

Newcastle AuthorsTitleYearFull text
Dr Anthony Oxley
Phil Berry
Gordon Taylor
Dr Joe Cowell
Dr Michael Hall
et al.
An LC/MS/MS method for stable isotope dilution studies of β-carotene bioavailability, bioconversion and vitamin A status in humans2014
Dr Sally Coulthard
Dr Chris Redfern
Svante Vikingsson
Dr Malin Lindqvist Appell
Dr Andrew Hall
et al.
Increased Sensitivity to Thiopurines in Methylthioadenosine Phosphorylase-Deleted Cancers2011
Dr Simon Pridgeon
Professor Rakesh Heer
Gordon Taylor
Professor Herbie Newell
Kieran O'Toole
et al.
Thiothymidine combined with UVA as a potential novel therapy for bladder cancer2011
Huw Thomas
Gordon Taylor
Professor Herbie Newell
Professor Alan Boddy
An evaluation of thymidine phosphorylase as a means of preventing thymidine rescue from the thymidylate synthase inhibitor raltitrexed2007
Dr Jane Renwick
Gordon Taylor
Huw Thomas
Professor Alan Boddy
Dr Chris Redfern
et al.
Molecular targeting of retinoic acid metabolism in neuroblastoma: The role of the CYP26 inhibitor R116010 in vitro and in vivo2007
Professor Caroline Relton
Gordon Taylor
Professor Patrick Chinnery
Emeritus Professor Doug Turnbull
Mitochondrial DNA mutations in individuals occupationally exposed to ionizing radiation2006
Professor Nick Reynolds
Dr Helen Anderson
Gordon Taylor
Dr Andrew Hall
Dr Linda Hogarth
et al.
Thioguanine nucleotide levels correlate with clinical response in atopic eczema patients treated with azathioprine2006
Dr Simon Meggitt
Professor Nick Reynolds
Dr Helen Anderson
Gordon Taylor
Dr Andrew Hall
et al.
Thioguanine nucleotides in patients with moderate-to-severe atopic eczema treated with azathioprine2006
Professor Alan Boddy
Gordon Taylor
Dr Andrew Hughes
Professor Alan Calvert
Professor Herbie Newell
et al.
2-[11C]thymidine positron emission tomography as an indicator of thymidylate synthase inhibition in patients treated with AG3372003
Huw Thomas
Gordon Taylor
Professor Herbie Newell
Professor Alan Boddy
Potentiation of raltitrexed (RTX) in vitro by thymidine phosphorylase (TP) and TP distribution in vivo2003
Huw Thomas
Gordon Taylor
Professor Herbie Newell
Professor Alan Boddy
The in vivo distribution of a CEA directed antibody conjugated to thymidine phosphorylase2002
Gordon Taylor
Huw Thomas
Professor Herbie Newell
Professor Nicola Curtin
Hypoxanthine transport in human tumour cell lines. Relationship to the inhibition of hypoxanthine rescue by dipyridamole2001
Professor Robert Taylor
Gordon Taylor
Dr Steve Durham
Emeritus Professor Doug Turnbull
The determination of complete human mitochondrial DNA sequences in single cells: implications for the study of somatic mitochondrial DNA point mutations2001
Gordon Taylor
Professor Herbie Newell
Development of a whole cell assay to measure methotrexate-induced inhibition of thymidylate synthase and de novo purine synthesis in leukaemia cells2000
Professor Alan Boddy
Gordon Taylor
A phase I study of the lipophilic thymidylate synthase inhibitor Thymitaq® (nolatrexed dihydrochloride) given by 10-day oral administration1999
Gordon Taylor
Professor John Lunec
Professor Andrew Pearson
Professor Herbie Newell
Impact of polyglutamation on sensitivity to raltitrexed and methotrexate in relation to drug-induced inhibition of de novo thymidylate and purine biosynthesis in CCRF-CEM cell lines1999
Gordon Taylor
Professor Herbie Newell
Professor Alan Boddy
Andrew Johnston
Professor Andrew Pearson
et al.
Deoxyuridine plasma levels during the phase I study of nolatrexed in children with advanced cancer1998
Professor Alan Boddy
Gordon Taylor
Professor Herbie Newell
Professor Alan Calvert
Preclinical and phase I clinical studies with the nonclassical antifolate thymidylate synthase inhibitor nolatrexed dihydrochloride given prolonged administration in patients with solid tumors1998
Professor Alan Calvert
Dr Andrew Hall
Professor John Lunec
Professor Herbie Newell
Professor Andrew Pearson
et al.
The relationship between intrinsic thymidylate synthase expression and sensitivity to THYMITAQ® in human leukaemia and colorectal carcinoma cell lines1997
Professor Steve Wedge
Fiona Chapman
Gordon Taylor
Huw Thomas
Professor Alan Boddy
et al.
A phase I clinical study of the antipurine antifolate lometrexol (DDATHF) given with oral folic acid1996
Gordon Taylor
Professor Alan Boddy
Professor Alan Calvert
Andrew Johnston
Professor Herbie Newell
et al.
Clinical pharmacokinetic and pharmacodynamic studies with the nonclassical antifolate thymidylate synthase inhibitor 3,4-dihydro-2-amino-6-methyl-4-oxo-5-(4-pyridplthio)-quinazolone dihydrochloride (AG337) given by 24-hour continuous intravenous infusion1995
Professor Steve Wedge
Gordon Taylor
Professor Alan Boddy
Professor Alan Calvert
Professor Herbie Newell
et al.
Clinical pharmacokinetics of the antipurine antifolate (6R)-5,10-dideaza-5,6,7,8-tetrahydrofolic acid (lometrexol) administered with an oral folic acid supplement1995
Professor Steve Wedge
Gordon Taylor
Professor Herbie Newell
Measurement of 5,10-dideaza-5,6,7,8-tetrahydrofolate (lometrexol) in human plasma and urine by high-performance liquid chromatography1995
Professor Herbie Newell
Gordon Taylor
Professor Alan Calvert
Phase I and pharmacokinetic study of a water-soluble etoposide prodrug, etoposide phosphate (BMY-40481)1995
Professor Herbie Newell
Gordon Taylor
Professor Alan Calvert
Thymidylate synthase - a target for anticancer drug design1989
Professor Alan Calvert
Gordon Taylor
Quinazoline antifolates with dual biochemical loci of action. Biochemical and Biological studies directed towards overcoming methotrexate resistance1980
Professor Alan Calvert
Gordon Taylor
The intracellular mechanism of action of metoprine (DDMP)1980