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Clonal Expansion of Early to Mid-Life Mitochondrial DNA Point Mutations Drives Mitochondrial Dysfunction during Human Ageing

Lookup NU author(s): Professor Laura GreavesORCiD, Marco Nooteboom, Dr Joanna ElsonORCiD, Dr Helen TuppenORCiD, Geoffrey Taylor, Dr Daniel Commane, Dr Ramesh Arasaradnam, Professor Robert TaylorORCiD, Emeritus Professor Thomas Kirkwood, Professor John MathersORCiD, Emeritus Professor Doug Turnbull

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Author(s): Greaves LC, Nooteboom M, Elson JL, Tuppen HAL, Taylor GA, Commane DM, Arasaradnam RP, Khrapko K, Taylor RW, Kirkwood TBL, Mathers JC, Turnbull DM

Publication type: Article

Publication status: Published

Journal: PLoS Genetics

Year: 2014

Volume: 10

Issue: 9

Online publication date: 18/09/2014

Acceptance date: 21/07/2014

Date deposited: 08/10/2014

ISSN (print): 1553-7390

ISSN (electronic): 1553-7404

Publisher: Public Library of Science

URL: http://dx.doi.org/10.1371/journal.pgen.1004620

DOI: 10.1371/journal.pgen.1004620

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