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Retinal organoid screening reveals ABT-737 and luminespib as potential agents against a cone- precursor-derived subtype of retinoblastoma

Lookup NU author(s): Dr Joe Kelk, Dr Agata Rozanska, Eleni Sotiriadou, Dan AstleyORCiD, Raf Hussain, Adrienne Unsworth, Dr Rachel QueenORCiD, Dr Jonathan Coxhead, Professor David SteelORCiD, Professor Lyle ArmstrongORCiD, Dr Ian HardcastleORCiD, Professor Gareth VealORCiD, Professor Majlinda LakoORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Publication metadata

Author(s): Kelk J, Rozanska A, Sotiriadou E, Astley D, Hussain R, Unsworth A, Gangar A, Robinson A, Queen R, Coxhead J, Steel DH, Armstrong L, Parulekar M, Hardcastle I, Veal GJ, Lako M

Publication type: Article

Publication status: Published

Journal: Molecular Therapy - Oncology

Year: 2026

Volume: 34

Issue: 1

Print publication date: 19/03/2026

Online publication date: 19/02/2026

Acceptance date: 16/02/2026

Date deposited: 06/03/2026

ISSN (electronic): 2950-3299

Publisher: Cell Press

URL: https://doi.org/10.1016/j.omton.2026.201160

DOI: 10.1016/j.omton.2026.201160

Data Access Statement: The scRNA-seq data are submitted to the Gene Expression Omnibus under the accession number GSE305503.


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Funding

Funder referenceFunder name
EPSRC/ERC (EP/Y031016/1)
Fight for Sight
Little Princess Trust (CCLGA 2022 18)
UKRI MRC Capital Funding for World Class Labs Award (MR/X012360/1)

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