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Browsing publications by Dr Jonathan Coxhead.

Newcastle AuthorsTitleYearFull text
Hannah Smith
Francesco Kumara Mastrorosa
Dr Giles Holt
Dr Brendan Houston
Dr Bilal Alobaidi
et al.
A de novo paradigm for male infertility2022
Dr Paul Donaghy
Dr Simon Cockell
Dr Carmen Martin-Ruiz
Dr Jonathan Coxhead
Dr Joseph Kane
et al.
Blood mRNA expression in Alzheimer’s disease and dementia with Lewy bodies2022
Andrea Masi
Dr Chris Lamb
Dr Simon Cockell
Dr Jonathan Coxhead
Professor Nicholas Embleton
et al.
Distinct gene expression profiles between human preterm- and adult-derived intestinal organoids exposed to Enterococcus faecalis: A pilot study2022
Dr Angela Pyle
Dr Helen Griffin
Dr Jonathan Coxhead
Raf Hussain
Dr Gavin Hudson
et al.
Heteroplasmic mitochondrial DNA variants in cardiovascular diseases2022
Dr Deepali Pal
Dr Helen Blair
Sean Hockney
Dr Melanie Beckett
Mankaran Singh
et al.
hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia2022
Dr Agata Rozanska
Rodrigo Cerna Chavez
Dr Rachel Queen
Dr Joseph Collin
Dr Darin Zerti
et al.
pRB-depleted pluripotent stem cell retinal organoids recapitulate cell state transitions of retinoblastoma development and suggest an important role for pRB in retinal cell differentiation2022
Dr Marina Danilenko
Dr Claire Keeling
Dr Stephen Crosier
Dr Martina Finetti
Dr Daniel Williamson
et al.
Single-cell DNA sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development2022
Ramada Khasawneh
Dr Ralf Kist
Dr Rachel Queen
Raf Hussain
Dr Jonathan Coxhead
et al.
Msx1 haploinsufficiency modifies the Pax9-deficient cardiovascular phenotype2021
Dr Laura Jardine
Dr Simone Webb
Issac Goh
Dr Gary Reynolds
Dr Michael Mather
et al.
Blood and immune development in human fetal bone marrow and Down syndrome2021
Catherine Hatton
Dr Rachel Botting
Dr Maria Duenas Fadic
Dr Iram Haq
Dr Bernard Verdon
et al.
Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-22021
Dr Gary Reynolds
Dr Peter Vegh
Dr James Fletcher
Dr Beth Poyner
Emily Stephenson
et al.
Developmental cell programs are co-opted in inflammatory skin disease2021
Emily Stephenson
Dr Gary Reynolds
Dr Rachel Botting
Justin Engelbert
Dr Bayanne Olabi
et al.
Single-cell multi-omics analysis of the immune response in COVID-192021
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Dr Birthe Hilgen
Maria Georgiou
et al.
Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface2020
Dr Hannah Lowes
Dr Fiona Robertson
Dr Angela Pyle
Raf Hussain
Dr Jonathan Coxhead
et al.
The Human Coronavirus Receptor ANPEP (CD13) Is Overexpressed in Parkinson's Disease2020
Dr Joseph Collin
Dr Darin Zerti
Dr Rachel Queen
Dr Roman Bauer
Dr Jonathan Coxhead
et al.
CRX Expression in Pluripotent Stem Cell‐Derived Photoreceptors Marks a Transplantable Subpopulation of Early Cones2019
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Dr Birthe Hilgen
Raf Hussain
et al.
Deconstructing Retinal Organoids: Single cell RNA-Seq reveals the cellular components of human pluripotent stem cell-derived retina2019
Dr Kirsty Hodgson
Dr Ed Schwalbe
Dr Jonathan Coxhead
Naomi Sinclair
Dr Simon Cockell
et al.
Epigenetic modifiers DNMT3A and BCOR are recurrently mutated in CYLD cutaneous syndrome2019
Dr Christopher Duncan
Angela Grainger
Andrew Skelton
Raf Hussain
Dr Joe Willet
et al.
Early-onset autoimmune disease due to a heterozygous loss-of-function mutation in TNFAIP3 (A20)2018
Dr Lauren Walker
Dr Jonathan Coxhead
Dr Ian Wilson
Dr Matthew Bashton
Dr Christopher Morris
et al.
High prevalence of focal and multi-focal somatic genetic variants in the human brain2018
Dr Vasileios Floros
Dr Angela Pyle
Dr Wei Wei
Dr Brendan Payne
Dr Jonathan Coxhead
et al.
Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos2018
Dr Michael Keogh
Dr Wei Wei
Dr Ian Wilson
Dr Jonathan Coxhead
Dr Helen Griffin
et al.
Genetic compendium of 1511 human brains available through the UK Medical Research Council Brain Banks Network Resource2017
Dr Michael Keogh
Dr Ian Wilson
Dr Jonathan Coxhead
Dr Helen Griffin
Dr Marzena Kurzawa-Akanbi
et al.
Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains2017
Emerita Professor Susan Lindsay
Dr Yaobo Xu
Dr Steven Lisgo
Lauren Harkin
Dr Gavin Clowry
et al.
HDBR Expression: A Unique Resource for Global and Individual Gene Expression Studies during Early Human Brain Development2016
Dr Jonathan Coxhead
Dr Marzena Kurzawa-Akanbi
Raf Hussain
Dr Angela Pyle
Professor Patrick Chinnery
et al.
Somatic mtDNA variation is an important component of Parkinson's disease2016
Dr Brendan Payne
Kris Gardner
Dr Jonathan Coxhead
Professor Patrick Chinnery
Deep Resequencing of Mitochondrial DNA2015
Dr Angela Pyle
Dr Gavin Hudson
Dr Ian Wilson
Dr Jonathan Coxhead
Tania Smertenko
et al.
Extreme-Depth Re-sequencing of Mitochondrial DNA Finds No Evidence of Paternal Transmission in Humans2015
Dr Charalampos Tzoulis
Dr Jonathan Coxhead
Dr Brendan Payne
Professor Patrick Chinnery
Professor Laurence Bindoff
et al.
Molecular Pathogenesis of Polymerase Gamma-Related Neurodegeneration2014
Dr Gerald Pfeffer
Professor Grainne Gorman
Dr Helen Griffin
Dr Marzena Kurzawa-Akanbi
Dr Ian Wilson
et al.
Mutations in the SPG7 gene cause chronic progressive external ophthalmoplegia through disordered mitochondrial DNA maintenance2014
Dr Maria Lastowska
Hani Al-Afghani
Haya AL-Balool
Harsh SHETH
Dr Jonathan Coxhead
et al.
Identification of a neuronal transcription factor network involved in medulloblastoma development2013
Smatanova Borras
Dayne Bromley
Philip Scully
Dr Jonathan Coxhead
Dr Ann Curtis
et al.
'Noonan Spectrum Test' - comprehensive screening for RASopathies2012
Dr Brendan Payne
Dr Ian Wilson
Dr Patrick Yu Wai Man
Dr Jonathan Coxhead
Professor David Deehan
et al.
Universal heteroplasmy of human mitochondrial DNA2012
Haya AL-Balool
Dr Mark Wade
Dr Jonathan Coxhead
Professor Julie Irving
Professor David Elliott
et al.
Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant2011
Dr Jonathan Coxhead
Seamus Kelly
Professor John Mathers
Differential antineoplastic effects of butyrate in cells with and without a functioning DNA mismatch repair2010
Dr Jonathan Coxhead
Seamus Kelly
Professor Sir John Burn
Professor John Mathers
Cell kinetics and gene expression changes in colorectal cancer patients given resistant starch: a randomised controlled trial2009
Dr Mark Leaver
Dr Patricia Dominguez Cuevas
Dr Jonathan Coxhead
Dr Richard Daniel
Professor Jeff Errington FRS
et al.
Life without a wall or division machine in Bacillus subtilis2009
Dr Jonathan Coxhead
Professor Sir John Burn
Dr Ann Curtis
Early experiences in amplicon sequencing using the Roche GS-FLX massively parallel DNA sequencer and its application within a diagnostic laboratory2008
Dr Jonathan Coxhead
Seamus Kelly
Professor John Mathers
Role of DNA-mismatch repair in anti-neoplastic effects of butyrate2008
Professor John Mathers
Dr Jonathan Coxhead
Dr John Tyson
Nutrition and DNA repair - Potential molecular mechanisms of action2007
Dr Jonathan Coxhead
Seamus Kelly
Professor John Mathers
Role of resistant starch in colorectal cancer prevention: A prospective randomised controlled trial2007
Dr Jonathan Coxhead
Wendy Bal
Dr Liz Williams
Professor John Mathers
Reactive oxygen species generation in mismatch repair-proficient and -deficient colorectal cancer cell lines exposed to butyrate2006
Dr Jonathan Coxhead
Dr Liz Williams
Professor John Mathers
DNA mismatch repair status may influence anti-neoplastic effects of butyrate2005
Dr Jonathan Coxhead
Wendy Bal
Dr Brian Shenton
Dr Liz Williams
Professor John Mathers
et al.
Effect of butyrate on induction of aneuploidy in colorectal carcinoma cell lines2005
Dr Liz Williams
Dr Jonathan Coxhead
Professor John Mathers
Anti-cancer effects of butyrate: Use of micro-array technology to investigate mechanisms2003