Tegan McTaggart Jing Lim Dr Katie Smith Bronagh Heaney Dr David McDonald et al. | Deep phenotyping of T regulatory cells in psoriatic arthritis highlights targetable mechanisms of disease | 2025 |
|
Dr Jamie Soul Yao Hao Hua Lin Dr Katarzyna Pirog Dr Jonathan Coxhead et al. | Comparative transcriptomic analysis of articular cartilage of post-traumatic osteoarthritis mouse models. | 2024 |
|
Marina Moya-Molina Emily Flood Dr Jonathan Coxhead Dr Graham Smith Professor Lyle Armstrong et al. | Deciphering the impact of PROM1 alternative splicing on human photoreceptor development and maturation | 2024 |
|
Dr Joseph Collin Dr Agata Rozanska Dr Veronika Boczonadi Marina Moya Molina Adrienne Unsworth et al. | Deciphering the spatio-temporal transcriptional and chromatin accessibility of human retinal organoid development at the single cell level | 2024 |
|
Ben Whittle Dr Hannah Lowes Dr Dasha Deen Dr Angela Pyle Dr Jonathan Coxhead et al. | Early-stage idiopathic Parkinson's disease is associated with reduced circular RNA expression | 2024 |
|
Dr Joseph Collin Dr Agata Rozanska Zerti Zerti Adrienne Unsworth Moira Crosier et al. | Single-cell analyses reveal transient retinal progenitor cells in the ciliary margin of developing human retina | 2024 |
|
Dr Ken Baker Dr David McDonald Dr Gill Hulme Raf Hussain Dr Jonathan Coxhead et al. | Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission | 2024 |
|
Dr Angela Pyle Dr Brendan Payne Dr Jonathan Coxhead Professor Gavin Hudson Moira Crosier et al. | Author Correction: Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos (Nature Cell Biology, (2018), 20, 2, (144-151), 10.1038/s41556-017-0017-8) | 2023 |
|
Jing Lim Grace Mallett Dr David McDonald Dr Gill Hulme Dr Stephanie Laba et al. | Programmed cell death-1 receptor-mediated regulation of Tbet+NK1.1- innate lymphoid cells within the tumor microenvironment | 2023 |
|
Rebecca Harris Dr Maninder Heer Dr Mark Levasseur Dr Tyrell Cartwright Beth Weston et al. | Release of Histone H3K4-reading transcription factors from chromosomes in mitosis is independent of adjacent H3 phosphorylation | 2023 |
|
Dr Joseph Collin Dr Megan Hasoon Zerti Zerti Sarah Hammadi Professor David Steel et al. | Single-cell RNA sequencing reveals transcriptional changes of human choroidal and retinal pigment epithelium cells during fetal development, in healthy adult and intermediate age-related macular degeneration | 2023 |
|
Dr Rachel Queen Moira Crosier Dr Lorraine Eley Dr Janet Kerwin Jasmin Turner et al. | Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves | 2023 |
|
Jason Powell Steven Powell Michael Mather Lauren Beck Dr Pawel Palmowski et al. | Tracheostomy in children is associated with neutrophilic airway inflammation | 2023 |
|
Hannah Smith Francesco Kumara Mastrorosa Dr Giles Holt Dr Brendan Houston Dr Bilal Alobaidi et al. | A de novo paradigm for male infertility | 2022 |
|
Dr Paul Donaghy Dr Simon Cockell Dr Carmen Martin-Ruiz Dr Jonathan Coxhead Dr Joseph Kane et al. | Blood mRNA expression in Alzheimer’s disease and dementia with Lewy bodies | 2022 |
|
Robert Jackson Catherine Hatton Dr Jarmila Spegarova Dr Maria Georgiou Dr Joseph Collin et al. | Conjunctival epithelial cells resist productive SARS-CoV-2 infection | 2022 |
|
Andrea Masi Professor Chris Lamb Dr Simon Cockell Dr Jonathan Coxhead Professor Nicholas Embleton et al. | Distinct gene expression profiles between human preterm- and adult-derived intestinal organoids exposed to Enterococcus faecalis: A pilot study | 2022 |
|
Dr Angela Pyle Dr Helen Griffin Dr Jonathan Coxhead Raf Hussain Professor Gavin Hudson et al. | Heteroplasmic mitochondrial DNA variants in cardiovascular diseases | 2022 |
|
Dr Deepali Pal Dr Helen Blair Sean Hockney Dr Melanie Beckett Mankaran Singh et al. | hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia | 2022 |
|
Dr Jill Hunter Dr Jacqueline Butterworth Helene Sellier Dr Nicola Hannaway Dr Saimir Luli et al. | Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance | 2022 |
|
Dr Agata Rozanska Rodrigo Cerna Chavez Dr Rachel Queen Dr Joseph Collin Dr Darin Zerti et al. | pRB-depleted pluripotent stem cell retinal organoids recapitulate cell state transitions of retinoblastoma development and suggest an important role for pRB in retinal cell differentiation | 2022 |
|
Dr Jill Hunter Dr Nicola Hannaway Scott Kerridge Dr Saimir Luli Dr Jacqueline Butterworth et al. | Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway | 2022 |
|
Dr Marzena Kurzawa-Akanbi Dr Florence Burte Dr Birthe Hilgen Dr Rachel Queen Dr Jonathan Coxhead et al. | Retinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer retina | 2022 |
|
Dr Marina Danilenko Dr Claire Keeling Dr Stephen Crosier Dr Martina Finetti Dr Daniel Williamson et al. | Single-cell DNA sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development | 2022 |
|
Lauren Beck Andrea Masi Professor Chris Lamb Rachel Smith Dr Jonathan Coxhead et al. | Strain-specific impacts of probiotics are a significant driver of gut microbiome development in very preterm infants | 2022 |
|
Dr Jill Hunter Scott Kerridge Dr Nicola Hannaway Dr Saimir Luli Dr Iglika Ivanova et al. | Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells | 2022 |
|
Ramada Khasawneh Dr Ralf Kist Dr Rachel Queen Raf Hussain Dr Jonathan Coxhead et al. | Msx1 haploinsufficiency modifies the Pax9-deficient cardiovascular phenotype | 2021 |
|
Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Dr Sanja Bojic Nicky Moyse et al. | A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells | 2021 |
|
Dr Laura Jardine Dr Simone Webb Issac Goh Dr Gary Reynolds Dr Michael Mather et al. | Blood and immune development in human fetal bone marrow and Down syndrome | 2021 |
|
Catherine Hatton Dr Rachel Botting Dr Maria Duenas Fadic Dr Iram Haq Dr Bernard Verdon et al. | Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2 | 2021 |
|
Dr Gary Reynolds Dr Peter Vegh Dr James Fletcher Dr Beth Poyner Dr Emily Stephenson et al. | Developmental cell programs are co-opted in inflammatory skin disease | 2021 |
|
Emily Stephenson Dr Gary Reynolds Dr Rachel Botting Justin Engelbert Dr Bayanne Olabi et al. | Single-cell multi-omics analysis of the immune response in COVID-19 | 2021 |
|
Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Dr Birthe Hilgen Maria Georgiou et al. | Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface | 2020 |
|
Dr Hannah Lowes Dr Fiona Robertson Dr Angela Pyle Raf Hussain Dr Jonathan Coxhead et al. | The Human Coronavirus Receptor ANPEP (CD13) Is Overexpressed in Parkinson's Disease | 2020 |
|
Dr Joseph Collin Dr Darin Zerti Dr Rachel Queen Dr Roman Bauer Dr Jonathan Coxhead et al. | CRX Expression in Pluripotent Stem Cell‐Derived Photoreceptors Marks a Transplantable Subpopulation of Early Cones | 2019 |
|
Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Dr Birthe Hilgen Raf Hussain et al. | Deconstructing Retinal Organoids: Single cell RNA-Seq reveals the cellular components of human pluripotent stem cell-derived retina | 2019 |
|
Dr Kirsty Hodgson Dr Ed Schwalbe Dr Jonathan Coxhead Naomi Sinclair Dr Simon Cockell et al. | Epigenetic modifiers DNMT3A and BCOR are recurrently mutated in CYLD cutaneous syndrome | 2019 |
|
Dr Christopher Duncan Angela Grainger Andrew Skelton Raf Hussain Dr Joe Willet et al. | Early-onset autoimmune disease due to a heterozygous loss-of-function mutation in TNFAIP3 (A20) | 2018 |
|
Dr Lauren Walker Dr Jonathan Coxhead Dr Ian Wilson Dr Matthew Bashton Dr Christopher Morris et al. | High prevalence of focal and multi-focal somatic genetic variants in the human brain | 2018 |
|
Dr Vasileios Floros Dr Angela Pyle Dr Wei Wei Dr Brendan Payne Dr Jonathan Coxhead et al. | Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos | 2018 |
|
Dr Michael Keogh Dr Wei Wei Dr Ian Wilson Dr Jonathan Coxhead Dr Helen Griffin et al. | Genetic compendium of 1511 human brains available through the UK Medical Research Council Brain Banks Network Resource | 2017 |
|
Dr Michael Keogh Dr Ian Wilson Dr Jonathan Coxhead Dr Helen Griffin Dr Marzena Kurzawa-Akanbi et al. | Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains | 2017 |
|
Emerita Professor Susan Lindsay Dr Yaobo Xu Dr Steven Lisgo Lauren Harkin Dr Gavin Clowry et al. | HDBR Expression: A Unique Resource for Global and Individual Gene Expression Studies during Early Human Brain Development | 2016 |
|
Dr Jonathan Coxhead Dr Marzena Kurzawa-Akanbi Raf Hussain Dr Angela Pyle Professor Patrick Chinnery et al. | Somatic mtDNA variation is an important component of Parkinson's disease | 2016 |
|
Dr Brendan Payne Kris Gardner Dr Jonathan Coxhead Professor Patrick Chinnery
| Deep Resequencing of Mitochondrial DNA | 2015 |
|
Dr Angela Pyle Professor Gavin Hudson Dr Ian Wilson Dr Jonathan Coxhead Tania Smertenko et al. | Extreme-Depth Re-sequencing of Mitochondrial DNA Finds No Evidence of Paternal Transmission in Humans | 2015 |
|
Dr Charalampos Tzoulis Dr Jonathan Coxhead Dr Brendan Payne Professor Patrick Chinnery Professor Laurence Bindoff et al. | Molecular Pathogenesis of Polymerase Gamma-Related Neurodegeneration | 2014 |
|
Dr Gerald Pfeffer Professor Grainne Gorman Dr Helen Griffin Dr Marzena Kurzawa-Akanbi Dr Ian Wilson et al. | Mutations in the SPG7 gene cause chronic progressive external ophthalmoplegia through disordered mitochondrial DNA maintenance | 2014 |
|
Dr Maria Lastowska Hani Al-Afghani Haya AL-Balool Harsh SHETH Dr Jonathan Coxhead et al. | Identification of a neuronal transcription factor network involved in medulloblastoma development | 2013 |
|
Smatanova Borras Dayne Bromley Philip Scully Dr Jonathan Coxhead Dr Ann Curtis et al. | 'Noonan Spectrum Test' - comprehensive screening for RASopathies | 2012 |
|
Dr Brendan Payne Dr Ian Wilson Dr Patrick Yu Wai Man Dr Jonathan Coxhead Professor David Deehan et al. | Universal heteroplasmy of human mitochondrial DNA | 2012 |
|
Haya AL-Balool Dr Mark Wade Dr Jonathan Coxhead Professor Julie Irving Professor David Elliott et al. | Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant | 2011 |
|
Dr Jonathan Coxhead Seamus Kelly Professor John Mathers
| Differential antineoplastic effects of butyrate in cells with and without a functioning DNA mismatch repair | 2010 |
|
Dr Jonathan Coxhead Seamus Kelly Professor Sir John Burn Professor John Mathers
| Cell kinetics and gene expression changes in colorectal cancer patients given resistant starch: a randomised controlled trial | 2009 |
|
Dr Mark Leaver Dr Patricia Dominguez Cuevas Dr Jonathan Coxhead Dr Richard Daniel Professor Jeff Errington et al. | Life without a wall or division machine in Bacillus subtilis | 2009 |
|
Dr Jonathan Coxhead Professor Sir John Burn Dr Ann Curtis
| Early experiences in amplicon sequencing using the Roche GS-FLX massively parallel DNA sequencer and its application within a diagnostic laboratory | 2008 |
|
Dr Jonathan Coxhead Seamus Kelly Professor John Mathers
| Role of DNA-mismatch repair in anti-neoplastic effects of butyrate | 2008 |
|
Professor John Mathers Dr Jonathan Coxhead Dr John Tyson
| Nutrition and DNA repair - Potential molecular mechanisms of action | 2007 |
|
Dr Jonathan Coxhead Seamus Kelly Professor John Mathers
| Role of resistant starch in colorectal cancer prevention: A prospective randomised controlled trial | 2007 |
|
Dr Jonathan Coxhead Wendy Bal Dr Liz Williams Professor John Mathers
| Reactive oxygen species generation in mismatch repair-proficient and -deficient colorectal cancer cell lines exposed to butyrate | 2006 |
|
Dr Jonathan Coxhead Dr Liz Williams Professor John Mathers
| DNA mismatch repair status may influence anti-neoplastic effects of butyrate | 2005 |
|
Dr Jonathan Coxhead Wendy Bal Dr Brian Shenton Dr Liz Williams Professor John Mathers et al. | Effect of butyrate on induction of aneuploidy in colorectal carcinoma cell lines | 2005 |
|
Dr Liz Williams Dr Jonathan Coxhead Professor John Mathers
| Anti-cancer effects of butyrate: Use of micro-array technology to investigate mechanisms | 2003 |
|