Publications by Dr Rachel Queen - ePrints

Browsing publications by Dr Rachel Queen.

Newcastle Authors	Title	Year
Dr Joseph Collin Dr Agata Rozanska Dr Veronika Boczonadi Marina Moya Molina Adrienne Unsworth et al.	Deciphering the spatio-temporal transcriptional and chromatin accessibility of human retinal organoid development at the single cell level	2024
Rob Atkinson Dr Maria Georgiou Dr Chunbo Yang Marina Moya Molina Dr Joseph Collin et al.	PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5´-splice-site selection causing tissue-specific defects	2024
Esther Fernández-Simón Rasya Gokul Nath Adrienne Unsworth Dr Marianela Schiava Professor Giorgio Tasca et al.	Single cell RNA sequencing of human FAPs reveals different functional stages in Duchenne muscular dystrophy	2024
Dr Joseph Collin Dr Agata Rozanska Zerti Zerti Adrienne Unsworth Moira Crosier et al.	Single-cell analyses reveal transient retinal progenitor cells in the ciliary margin of developing human retina	2024
Dr Valeria Chichagova Dr Maria Georgiou Madeleine Carter Dr Gerrit Hilgen Dr Joseph Collin et al.	Incorporating microglia-like cells in human induced pluripotent stem cell-derived retinal organoids	2023
Lefteris Zormpas Dr Rachel Queen Dr Simon Cockell	Mapping the transcriptome: Realizing the full potential of spatial data analysis	2023
Dr Joseph Collin Dr Megan Hasoon Zerti Zerti Sarah Hammadi Professor David Steel et al.	Single-cell RNA sequencing reveals transcriptional changes of human choroidal and retinal pigment epithelium cells during fetal development, in healthy adult and intermediate age-related macular degeneration	2023
Dr Rachel Queen	Spatial Gene Expression Changes in the Mouse Heart After Base-targeted Irradiation	2023
Dr Rachel Queen Moira Crosier Dr Lorraine Eley Dr Janet Kerwin Jasmin Turner et al.	Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves	2023
Robert Jackson Catherine Hatton Dr Jarmila Spegarova Dr Maria Georgiou Dr Joseph Collin et al.	Conjunctival epithelial cells resist productive SARS-CoV-2 infection	2022
Dr Maria Georgiou Alex Chaudhary Dr Joseph Collin Dr Rachel Queen Dr Birthe Hilgen et al.	Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: A Comprehensive Validation Using Drugs and Compounds Affecting the Retina	2022
Dr Agata Rozanska Rodrigo Cerna Chavez Dr Rachel Queen Dr Joseph Collin Dr Darin Zerti et al.	pRB-depleted pluripotent stem cell retinal organoids recapitulate cell state transitions of retinoblastoma development and suggest an important role for pRB in retinal cell differentiation	2022
Dr Marzena Kurzawa-Akanbi Dr Florence Burte Dr Birthe Hilgen Dr Rachel Queen Dr Jonathan Coxhead et al.	Retinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer retina	2022
Ramada Khasawneh Dr Ralf Kist Dr Rachel Queen Raf Hussain Dr Jonathan Coxhead et al.	Msx1 haploinsufficiency modifies the Pax9-deficient cardiovascular phenotype	2021
Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Dr Sanja Bojic Nicky Moyse et al.	A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells	2021
Dr Laura Jardine Dr Simone Webb Issac Goh Dr Gary Reynolds Dr Michael Mather et al.	Blood and immune development in human fetal bone marrow and Down syndrome	2021
Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Professor David Steel Professor Majlinda Lako et al.	Dissecting the transcriptional and chromatin accessibility heterogeneity of proliferating cone precursors in human retinoblastoma tumours by single cell sequencing- opening pathways to new therapeutic strategies?	2021
Professor Lyle Armstrong Dr Joseph Collin Dr Islam Mostafa Dr Rachel Queen Professor Francisco Figueiredo et al.	In the eye of the storm: SARS-CoV-2 infection and replication at the ocular surface?	2021
Dr Rachel Queen Professor Majlinda Lako Zerti Zerti	Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics	2021
Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Dr Birthe Hilgen Maria Georgiou et al.	Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface	2020
Dr Urszula Cytlak-Chaudhuri Dr Anastasia Resteu Sarah Pagan Dr Kile Green Dr Paul Milne et al.	Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans	2020
Dr Rachel Queen Professor Majlinda Lako	SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes	2020
Dr Rachel Queen Dr Darin Zerti	SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes	2020
Dr Olivier Govaere Dr Simon Cockell Dr Dina Tiniakos Dr Rachel Queen Dr Massimo Younes et al.	Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis	2020
Dr Rachel Queen Dr Simon Cockell Professor Majlinda Lako	Understanding the complexity of retinal and pluripotent stem cell derived retinal organoids with single cell RNA sequencing: current progress, remaining challenges and future prospectives	2020
Hannah O'Keefe Dr Rachel Queen Dr Phillip Lord Dr Joanna Elson	What can a comparative genomics approach tell us about the pathogenicity of mtDNA mutations in human populations?	2020
Dr Joseph Collin Dr Darin Zerti Dr Rachel Queen Dr Roman Bauer Dr Jonathan Coxhead et al.	CRX Expression in Pluripotent Stem Cell‐Derived Photoreceptors Marks a Transplantable Subpopulation of Early Cones	2019
Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Dr Birthe Hilgen Raf Hussain et al.	Deconstructing Retinal Organoids: Single cell RNA-Seq reveals the cellular components of human pluripotent stem cell-derived retina	2019
Dr Carla Jackson Dr Joseph Collin Dr Rachel Queen Dr Birthe Hilgen Dr Darin Zerti et al.	Systematic Comparison of Retinal Organoid Differentiation from Human Pluripotent Stem Cells Reveals Stage Specific, Cell Line, and Methodological Differences	2019
Dr Sanja Bojic Dr Dean Hallam Nuno Alcada Dr Ali Ghareeb Dr Rachel Queen et al.	CD200 expression marks a population of quiescent limbal epithelial stem cells with holoclone forming ability	2018
Hannah O'Keefe Dr Rachel Queen Dr Phillip Lord Dr Joanna Elson	Haplogroup Context is Less Important in the Penetrance of Mitochondrial DNA Complex I Mutations Compared to mt-tRNA Mutations	2018
Dr Rachel Queen Dr Jannetta Steyn Dr Phillip Lord Dr Joanna Elson	Mitochondrial DNA sequence context in the penetrance of mitochondrial t-RNA mutations: A study across multiple lineages with diagnostic implications	2017