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Therapy and biomarker dependent progression-free survival in infant sonic hedgehog medulloblastoma: a multi-national retrospective cohort study

Lookup NU author(s): Dr Stacey RichardsonORCiD, Dr Debbie HicksORCiD, Melissa Gough, Ellie Butler, Dr Dean Thompson, Dr Jemma CastleORCiD, Dr Stephen Crosier, Dr Ed Schwalbe, Professor Simon BaileyORCiD, Professor Steven CliffordORCiD

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Author(s): Richardson S, Hicks D, Gough M, Butler ER, Thompson D, Castle J, Crosier S, Garcia-Ariza M, Martin-Guerrero I, Plasschaert SLA, Bourdeaut F, Dufour C, Masliah-Planchon J, Buttarelli FR, Biassoni V, Massimino M, Ichimura K, Kanemura Y, Ramaswamy V, Gajjar A, Kool M, Korshunov A, Pfister SM, Mynarek M, Rutkowski S, Schwalbe EC, Bailey S, Clifford SC

Publication type: Article

Publication status: Published

Journal: eClinicalMedicine

Year: 2026

Volume: 96

Print publication date: 01/06/2026

Online publication date: 18/05/2026

Acceptance date: 02/04/2026

Date deposited: 10/07/2026

ISSN (electronic): 2589-5370

Publisher: Elsevier Ltd

URL: https://doi.org/10.1016/j.eclinm.2026.103913

DOI: 10.1016/j.eclinm.2026.103913

Data Access Statement: Raw and processed DNA methylation microarray data and associated patient metadata have been deposited in the NCBI Gene Expression Omnibus (GEO) with accession number GSE317378. This submission also contains data and metadata from our study on non-WNT/non-SHH infant medulloblastoma. https://doi.org/10.1016/S2352-4642(26)00067-2

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