Publications by Dr Ed Schwalbe - ePrints

Browsing publications by Dr Ed Schwalbe.

Newcastle Authors	Title	Year
Dr Ed Schwalbe Dr Janet Lindsey Dr Marina Danilenko Dr Rebecca Hill Dr Stephen Crosier et al.	Molecular and clinical heterogeneity within MYC-family amplified medulloblastoma is associated with survival outcomes: A multicenter cohort study	2025
Dr Claire Keeling Dr Jack Goddard Dr Ed Schwalbe Professor Simon Bailey Dr Debbie Hicks et al.	MDB-31. The clinical significance of sub-total surgical resection in childhood medulloblastoma: a multi-cohort analysis of 1100 patients.	2024
Dr Marion Mateos Dr Daniel Williamson Dr Marina Danilenko Dr Jack Goddard Dr Stephen Crosier et al.	MDB-64. Novel transcripts associate with survival in childhood medulloblastoma.	2024
Dr Claire Keeling Dr Jack Goddard Dr Ed Schwalbe Professor Simon Bailey Dr Debbie Hicks et al.	The clinical significance of sub-total surgical resection in childhood medulloblastoma: a multi-cohort analysis of 1100 patients	2024
Dr Jack Goddard Jemma Castle Emily Southworth Anya Fletcher Dr Stephen Crosier et al.	Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification	2023
Wen Hao Professor Deborah Tweddle Dr Ed Schwalbe Dr Gordon Strathdee	Genome wide DNA methylation analysis identifies novel molecular subgroups and predicts survival in neuroblastoma	2022
Dr Jack Goddard Jemma Castle Dr Stephen Crosier Dr Daniel Williamson Dr Ed Schwalbe et al.	EMBR-25. Genome-wide genetic and epigenetic assessment of Group 4 medulloblastoma for improved, biomarker driven, prognostication and risk-stratification	2021
Dr John Perry Dr Ed Schwalbe	A chromatographic approach to distinguish Gram-positive from Gram-negative bacteria using exogenous volatile organic compound metabolites	2017
Dr Ed Schwalbe Dr Debbie Hicks Professor Steven Clifford	Health-Related Quality of Life (HRQoL) in HIT-SIOP-PNET4 trial survivors: differences between medulloblastoma molecular subgroups	2016
Dr Debbie Hicks Dr Ed Schwalbe Dr Stephen Crosier Professor Simon Bailey Dr Daniel Williamson et al.	Identification of medulloblastoma molecular subgroups using metabolite profiles	2016
Dr Janet Lindsey Dr Rebecca Hill Dr Ed Schwalbe Dr Christopher Howell Dr Reza Rafiee et al.	Molecular and Prognostic Heterogeneity within MYC and MYCN Amplified Medulloblastomas	2016
Dr Ed Schwalbe Dr Debbie Hicks Dr Reza Rafiee Dr Matthew Bashton Dr Amir Enshaei et al.	Routine Diagnostic Medulloblastoma Subgrouping Using Low-Cost, Low-Input DNA Methylomics: Application to Trials Cohorts Previously Refractory-to-Analysis	2016
Dr Ed Schwalbe Dr Debbie Hicks Dr Reza Rafiee Dr Matthew Bashton Dr Amir Enshaei et al.	Routine molecular subgrouping of medulloblastoma: Bridging the divide between research and the clinic using low-cost, mass spectrometry-based DNA methylomics	2016
Dr Debbie Hicks Dr Reza Rafiee Dr Ed Schwalbe Dr Christopher Howell Dr Janet Lindsey et al.	Subgroup-Directed Stratification of Risk in Infant Medulloblastoma	2016
Professor Steven Clifford Dr Ed Schwalbe Dr Debbie Hicks Kieran O'Toole Sarah Nicholson et al.	Biomarker-driven stratification of disease-risk in non-metastatic medulloblastoma: Results from the multi-center HIT-SIOP-PNET4 clinical trial	2015
Dr Janet Lindsey Dr Ed Schwalbe Matthew Selby Dr James Hayden Dr Daniel Williamson et al.	Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance	2015
Dr Al Gabriel Fadhel Alsaid Naji Dr Ed Schwalbe Dr Sirintra Nakjang Dr Simon Cockell et al.	Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia	2015
Dr Janet Lindsey Dr Ed Schwalbe Sandeep Potluri Professor Simon Bailey Dr Daniel Williamson et al.	TERT promoter mutation and aberrant hypermethylation are associated with elevated expression in medulloblastoma and characterise the majority of non-infant SHH subgroup tumours	2014
Dr Janet Lindsey Dr Ed Schwalbe Dr James Hayden Professor David Ellison Dr Daniel Williamson et al.	Cross-Species Epigenetics Identifies a Critial Role for VAV1 in the Maintenance of Sonic Hedgehog Subgroup Medulloblastomas	2014
Dr Rebecca Hill Dr Janet Lindsey Dr Ed Schwalbe Dr Daniel Williamson Dr Sarra Ryan et al.	MYC and TP53 defects emerge and interact at medulloblastoma relapse, define rapidly progressive disease and can be targeted therapeutically	2014
Dr Rebecca Hill Dr Janet Lindsey Dr Ed Schwalbe Dr Karen Barker Dr Daniel Williamson et al.	MYC and TP53 defects interact at medulloblastoma relapse to define rapidly progressive disease and can be targeted therapeutically	2014
Dr Ed Schwalbe Dr Debbie Hicks Dr Reza Rafiee Dr Amir Enshaei Sandeep Potluri et al.	Routine molecular subgrouping of medulloblastoma: Bridging the divide between research and the clinic using low-cost DNA methylomics	2014
Dr Ed Schwalbe Dr James Hayden Dr Janet Lindsey Dr Rebecca Hill Sarah Nicholson et al.	Histologically defined central nervous system primitive neuro-ectodermal tumours (CNS-PNETs) display heterogeneous DNA methylation profiles and show relationships to other paediatric brain tumour types	2013
Dr Peter Carey Claire Schwab Dr Lucy Chilton Dr Ed Schwalbe Professor Roderick Skinner et al.	Treating childhood acute lymphoblastic leukemia in Malawi	2013
Dr Ed Schwalbe Dr Janet Lindsey Dr Daniel Williamson Kieran O'Toole Dr Meryl Lusher et al.	Epigenetic sub-classification and risk-stratification of medulloblastoma using DNA methylomics	2012
Dr Ed Schwalbe Professor Steven Clifford	Supratentorial and spinal pediatric ependymomas display a hypermethylated phenotype which includes the loss of tumor suppressor genes involved in the control of cell growth and death	2012
Dr Ed Schwalbe Professor Steven Clifford	Methylator phenotype of malignant germ cell tumours in children identifies strong candidates for chemotherapy resistance	2011
Dr Ed Schwalbe Dr Janet Lindsey Debbie Straughton Mike Cole Dr Hisham Megahed et al.	Rapid Diagnosis of Medulloblastoma Molecular Subgroups	2011
Dr Janet Lindsey Dr Rebecca Hill Dr Hisham Megahed Dr Meryl Lusher Dr Ed Schwalbe et al.	TP53 Mutations in Favorable-Risk Wnt/Wingless-Subtype Medulloblastomas	2011
Dr Ed Schwalbe Professor Steven Clifford Dr Richard Gilbertson	Characteristic Genomic Imbalances in Paediatric Ependyoma; The Importance of Chromosome 1Q Gain	2010
Dr Ed Schwalbe Dr Janet Lindsey Dr Meryl Lusher Kieran O'Toole Sarah Nicholson et al.	DNA methylomics identifies clinically significant epigenetic subgroups of medulloblastoma	2010
Dr James Hayden Dr Matthew Allen Dr Sarra Ryan Sarah Nicholson Dr Ed Schwalbe et al.	Molecular Mechanisms in Supratentorial CNS-PNET development	2010