Publications by Dr Stephen Crosier - ePrints

Browsing publications by Dr Stephen Crosier.

Newcastle Authors	Title	Year
Dr Ed Schwalbe Dr Janet Lindsey Dr Marina Danilenko Dr Rebecca Hill Dr Stephen Crosier et al.	Molecular and clinical heterogeneity within MYC-family amplified medulloblastoma is associated with survival outcomes: A multicenter cohort study	2025
Magretta Adiamah Beth Poole Dr Janet Lindsey Dr Rebecca Hill Dr Helen Blair et al.	MYC-dependent upregulation of the de novo serine and glycine synthesis pathway is a targetable metabolic vulnerability in group 3 medulloblastoma	2025
Dr Marion Mateos Dr Daniel Williamson Dr Marina Danilenko Dr Jack Goddard Dr Stephen Crosier et al.	MDB-64. Novel transcripts associate with survival in childhood medulloblastoma.	2024
Dr Florence Burté Magretta Adiamah Dr Fatma Scerif Dr Debbie Hicks Dr Ed Schwalbe et al.	Metabolite profiles of medulloblastoma for rapid and non-invasive detection of molecular disease groups	2024
Dr Jack Goddard Jemma Castle Emily Southworth Anya Fletcher Dr Stephen Crosier et al.	Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification	2023
Dr Stacey Richardson Dr Rebecca Hill Dr Christopher Kui Dr Janet Lindsey Dr Yura Grabovska et al.	Emergence and maintenance of actionable genetic drivers at medulloblastoma relapse	2022
Dr Daniel Williamson Dr Ed Schwalbe Dr Debbie Hicks Dr Janet Lindsey Dr Stephen Crosier et al.	Medulloblastoma group 3 and 4 tumors comprise a clinically and biologically significant expression continuum reflecting human cerebellar development	2022
Dr Marina Danilenko Dr Claire Keeling Dr Stephen Crosier Dr Martina Finetti Dr Daniel Williamson et al.	Single-cell DNA sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development	2022
Dr Stephen Crosier Dr Debbie Hicks Dr Ed Schwalbe Dr Daniel Williamson Amanda Smith et al.	Advanced molecular pathology for rare tumours: A national feasibility study and model for centralised medulloblastoma diagnostics	2021
Dr Debbie Hicks Dr Reza Rafiee Dr Ed Schwalbe Dr Christopher Howell Dr Janet Lindsey et al.	The molecular landscape and associated clinical experience in infant medulloblastoma: prognostic significance of second-generation subtypes	2021
Dr Stephen Crosier Professor Simon Bailey	Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes	2020
Dr Yura Grabovska Dr Stephen Crosier Dr Martina Finetti Dr Ed Schwalbe Dr Rebecca Hill et al.	Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity	2020
Dr Rebecca Hill Dr Stacey Richardson Dr Ed Schwalbe Dr Debbie Hicks Dr Janet Lindsey et al.	Time, pattern, and outcome of medulloblastoma relapse and their association with tumour biology at diagnosis and therapy: a multicentre cohort study	2020
Dr Ed Schwalbe Dr Debbie Hicks Dr Reza Rafiee Dr Matthew Bashton Dr Amir Enshaei et al.	Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures	2017
Dr Ed Schwalbe Dr Janet Lindsey Dr Sirintra Nakjang Dr Stephen Crosier Amanda Smith et al.	Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study	2017
Dr Stephen Crosier Dr Debbie Hicks Dr Ed Schwalbe Dr Daniel Williamson Sarah Nicholson et al.	Centralised Molecular Pathology for Rare Tumours: A National Feasibility Study of Real-Time Medulloblastoma Diagnostics	2016
Dr Martina Finetti Dr Stephen Crosier Dr Daniel Williamson	Dual Targeting of PDGFR alpha and FGFR1 Displays Synergistic Efficacy in Malignant Rhabdoid Tumors	2016
Professor Steven Clifford Dr Stephen Crosier Dr Debbie Hicks Stewart Nicholson Dr Nicholas Bown et al.	Establishment of national real-time central pathology review (CPR) and molecular diagnostics for medulloblastoma (MB)	2016
Dr Debbie Hicks Dr Ed Schwalbe Dr Stephen Crosier Professor Simon Bailey Dr Daniel Williamson et al.	Identification of medulloblastoma molecular subgroups using metabolite profiles	2016
Dr Martina Finetti Matthew Selby Dr Matthew Bashton Dr Ruth Cranston Dr Stephen Crosier et al.	Integrated pathway analysis of malignant rhabdoid tumour identifies key SMARCB1-pathways and therapeutic opportunities	2016
Dr Martina Finetti Alicia Del Carpio Pons James Barker James Wood Dr Sirintra Nakjang et al.	Integrated pathway analysis of rhabdoid tumor subtypes identifies key SMARCB1-dependencies and therapeutic opportunities	2016
Dr Janet Lindsey Dr Rebecca Hill Dr Ed Schwalbe Dr Christopher Howell Dr Reza Rafiee et al.	Molecular and Prognostic Heterogeneity within MYC and MYCN Amplified Medulloblastomas	2016
Dr Ed Schwalbe Dr Debbie Hicks Dr Reza Rafiee Dr Matthew Bashton Dr Amir Enshaei et al.	Routine Diagnostic Medulloblastoma Subgrouping Using Low-Cost, Low-Input DNA Methylomics: Application to Trials Cohorts Previously Refractory-to-Analysis	2016
Dr Ed Schwalbe Dr Debbie Hicks Dr Reza Rafiee Dr Matthew Bashton Dr Amir Enshaei et al.	Routine molecular subgrouping of medulloblastoma: Bridging the divide between research and the clinic using low-cost, mass spectrometry-based DNA methylomics	2016
Dr Debbie Hicks Dr Reza Rafiee Dr Ed Schwalbe Dr Christopher Howell Dr Janet Lindsey et al.	Subgroup-Directed Stratification of Risk in Infant Medulloblastoma	2016
Dr Daniel Williamson Dr Janet Lindsey Dr Debbie Hicks Dr Stephen Crosier Amanda Smith et al.	The Transcriptional Landscape of Medulloblastoma: Group 3 and Group 4 Tumours Comprise a Single Clinically Significant Expression Continuum	2016
Dr Mark Wade Dr Nicola Sunter Dr Sarah Fordham Anna Long Dino Mašić et al.	c-MYC is a radiosensitive locus in human breast cells	2015
Dr Rebecca Hill Dr Janet Lindsey Dr Ed Schwalbe Dr Karen Barker Dr Daniel Williamson et al.	Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease	2015
Dr Martina Finetti Alicia Del Carpio Pons Ben Skalkoyannis Matthew Selby Amanda Smith et al.	A Systems Biology Approach to Identify Mechanism of Tumourigenesis Caused by Loss of SMARCB1 in Malignant Rhabdoid Tumors (BACR28)	2014
Dr Martina Finetti Matthew Selby Dr Stephen Crosier Ben Skalkoyannis Professor Simon Bailey et al.	Characterising critical pathways in ATRT tumourigenesis: a genome-wide analysis of primary tumours and functional genomic models	2014
Dr Martina Finetti Ben Skalkoyannis Matthew Selby Dr Stephen Crosier Professor Simon Bailey et al.	Mechanism of tumourigenesis caused by loss of SMARCB1 in malignant rhabdoid tumors	2014
Dr Rebecca Hill Dr Janet Lindsey Dr Ed Schwalbe Dr Daniel Williamson Dr Sarra Ryan et al.	MYC and TP53 defects emerge and interact at medulloblastoma relapse, define rapidly progressive disease and can be targeted therapeutically	2014
Dr Rebecca Hill Dr Janet Lindsey Dr Ed Schwalbe Dr Karen Barker Dr Daniel Williamson et al.	MYC and TP53 defects interact at medulloblastoma relapse to define rapidly progressive disease and can be targeted therapeutically	2014
Dr Martina Finetti Matthew Selby Alicia Del Carpio Pons Ben Skalkoyannis Amanda Smith et al.	Next-generation sequencing identifies the mechanism of tumourigenesis caused by loss of SMARCB1 in malignant rhabdoid tumours	2014
Dr Ed Schwalbe Dr Debbie Hicks Dr Reza Rafiee Dr Amir Enshaei Sandeep Potluri et al.	Routine molecular subgrouping of medulloblastoma: Bridging the divide between research and the clinic using low-cost DNA methylomics	2014
Professor Steven Clifford Dr Stephen Crosier Sarah Nicholson Dr Nicholas Bown	A national feasibility study of real-time central pathology review (CPR) and molecular diagnostics for medulloblastoma	2013
Dr Stephen Crosier Sarah Nicholson Dr Nicholas Bown Professor Steven Clifford	A National Feasibility Study of Real-Time Central Pathology Review and Molecular Diagnostics for Medulloblastoma	2012
Dr Rachel Crossland Dr Christine Challen Dr Bridget Wilkins Dr Stephen Crosier Dr John Anderson et al.	Definitive identification of the Val617Phe mutation in myeloproliferative disorders using Real Time PCR utilising Roche Lightcycler/hybriprobe technology	2007
Dr John Anderson Dr Stephen Crosier Dr Jyotsna Shrimankar Professor John Lunec Dr Brian Angus et al.	Downregulation of nuclear expression of the p33^ING1binhibitor of growth protein in invasive carcinoma of the breast	2003
Dr Stephen Crosier Dr Katrina Wood Dr Philip Taylor Professor Stephen Proctor Dr Brian Angus et al.	IAP survivin in diffuse large B cell lymphoma: Evaluation as a prognostic marker	2003
Dr John Anderson Dr Marie Mathers Dr Niamh Leonard Dr Stephen Crosier Professor John Lunec et al.	Nuclear to cytoplasmic compartment shift of the p33ING1b tumour suppressor protein is associated with malignancy in melanocytic lesions	2002
Dr John Anderson Dr Stephen Crosier Dr Jyotsna Shrimankar Professor John Lunec Dr Brian Angus et al.	p33^ING1b tumour suppressor immunohistochemical expression in invasive breast carcinomas	2002
Dr Stephen Crosier Dr Brian Angus Dr John Anderson	Use of transgenomic wave and denaturing gel electrophoresis increases the sensitivity of FR3A-FR4 PCR detection of B-cell clonality	2002
Dr Stephen Crosier Dr John Anderson Dr Marie Mathers Dr Niamh Leonard Dr Stephen Crosier et al.	p33(ING1b) tumour suppresser protein expression in melanocytic lesions, an immunohistochemical study of 67 cases	2001
Dr John Anderson Dr Stephen Crosier Professor John Lunec Dr Brian Angus	p33^ING1b tumour suppresser protein expression in thyroid lesions determined by immunohistochemistry	2001
Professor Christopher Eggett Dr Stephen Crosier Dr Philip Manning Fiona Menzies Emeritus Professor Calum McNeil et al.	Development and characterisation of a glutamate-sensitive motor neurone cell line	2000