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Browsing publications by Dr Stephen Crosier.

Newcastle AuthorsTitleYearFull text
Dr Florence Burté
Magretta Adiamah
Dr Fatma Scerif
Dr Debbie Hicks
Dr Ed Schwalbe
et al.
Metabolite profiles of medulloblastoma for rapid and non-invasive detection of molecular disease groups2024
Dr Jack Goddard
Jemma Castle
Emily Southworth
Anya Fletcher
Dr Stephen Crosier
et al.
Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification2023
Dr Daniel Williamson
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Janet Lindsey
Dr Stephen Crosier
et al.
Medulloblastoma group 3 and 4 tumors comprise a clinically and biologically significant expression continuum reflecting human cerebellar development2022
Dr Marina Danilenko
Dr Claire Keeling
Dr Stephen Crosier
Dr Martina Finetti
Dr Daniel Williamson
et al.
Single-cell DNA sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development2022
Dr Stephen Crosier
Dr Debbie Hicks
Dr Ed Schwalbe
Dr Daniel Williamson
Amanda Smith
et al.
Advanced molecular pathology for rare tumours: A national feasibility study and model for centralised medulloblastoma diagnostics2021
Dr Debbie Hicks
Dr Reza Rafiee
Dr Ed Schwalbe
Dr Christopher Howell
Dr Janet Lindsey
et al.
The molecular landscape and associated clinical experience in infant medulloblastoma: prognostic significance of second-generation subtypes2021
Dr Stephen Crosier
Professor Simon Bailey
Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes2020
Dr Yura Grabovska
Dr Stephen Crosier
Dr Martina Finetti
Dr Ed Schwalbe
Dr Rebecca Hill
et al.
Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity2020
Dr Rebecca Hill
Dr Stacey Richardson
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Janet Lindsey
et al.
Time, pattern, and outcome of medulloblastoma relapse and their association with tumour biology at diagnosis and therapy: a multicentre cohort study2020
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Reza Rafiee
Dr Matthew Bashton
Dr Amir Enshaei
et al.
Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures2017
Dr Ed Schwalbe
Dr Janet Lindsey
Dr Sirintra Nakjang
Dr Stephen Crosier
Amanda Smith
et al.
Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study2017
Dr Stephen Crosier
Dr Debbie Hicks
Dr Ed Schwalbe
Dr Daniel Williamson
Sarah Nicholson
et al.
Centralised Molecular Pathology for Rare Tumours: A National Feasibility Study of Real-Time Medulloblastoma Diagnostics2016
Dr Martina Finetti
Dr Stephen Crosier
Dr Daniel Williamson
Dual Targeting of PDGFR alpha and FGFR1 Displays Synergistic Efficacy in Malignant Rhabdoid Tumors2016
Professor Steven Clifford
Dr Stephen Crosier
Dr Debbie Hicks
Stewart Nicholson
Dr Nicholas Bown
et al.
Establishment of national real-time central pathology review (CPR) and molecular diagnostics for medulloblastoma (MB)2016
Dr Debbie Hicks
Dr Ed Schwalbe
Dr Stephen Crosier
Professor Simon Bailey
Dr Daniel Williamson
et al.
Identification of medulloblastoma molecular subgroups using metabolite profiles2016
Dr Martina Finetti
Matthew Selby
Dr Matthew Bashton
Dr Ruth Cranston
Dr Stephen Crosier
et al.
Integrated pathway analysis of malignant rhabdoid tumour identifies key SMARCB1-pathways and therapeutic opportunities2016
Dr Martina Finetti
Alicia Del Carpio Pons
James Barker
James Wood
Dr Sirintra Nakjang
et al.
Integrated pathway analysis of rhabdoid tumor subtypes identifies key SMARCB1-dependencies and therapeutic opportunities2016
Dr Janet Lindsey
Dr Rebecca Hill
Dr Ed Schwalbe
Dr Christopher Howell
Dr Reza Rafiee
et al.
Molecular and Prognostic Heterogeneity within MYC and MYCN Amplified Medulloblastomas2016
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Reza Rafiee
Dr Matthew Bashton
Dr Amir Enshaei
et al.
Routine Diagnostic Medulloblastoma Subgrouping Using Low-Cost, Low-Input DNA Methylomics: Application to Trials Cohorts Previously Refractory-to-Analysis2016
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Reza Rafiee
Dr Matthew Bashton
Dr Amir Enshaei
et al.
Routine molecular subgrouping of medulloblastoma: Bridging the divide between research and the clinic using low-cost, mass spectrometry-based DNA methylomics2016
Dr Debbie Hicks
Dr Reza Rafiee
Dr Ed Schwalbe
Dr Christopher Howell
Dr Janet Lindsey
et al.
Subgroup-Directed Stratification of Risk in Infant Medulloblastoma2016
Dr Daniel Williamson
Dr Janet Lindsey
Dr Debbie Hicks
Dr Stephen Crosier
Amanda Smith
et al.
The Transcriptional Landscape of Medulloblastoma: Group 3 and Group 4 Tumours Comprise a Single Clinically Significant Expression Continuum2016
Dr Mark Wade
Dr Nicola Sunter
Dr Sarah Fordham
Anna Long
Dino Mašić
et al.
c-MYC is a radiosensitive locus in human breast cells2015
Dr Rebecca Hill
Dr Janet Lindsey
Dr Ed Schwalbe
Dr Karen Barker
Dr Daniel Williamson
et al.
Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease2015
Dr Martina Finetti
Alicia Del Carpio Pons
Ben Skalkoyannis
Matthew Selby
Amanda Smith
et al.
A Systems Biology Approach to Identify Mechanism of Tumourigenesis Caused by Loss of SMARCB1 in Malignant Rhabdoid Tumors (BACR28)2014
Dr Martina Finetti
Matthew Selby
Dr Stephen Crosier
Ben Skalkoyannis
Professor Simon Bailey
et al.
Characterising critical pathways in ATRT tumourigenesis: a genome-wide analysis of primary tumours and functional genomic models2014
Dr Martina Finetti
Ben Skalkoyannis
Matthew Selby
Dr Stephen Crosier
Professor Simon Bailey
et al.
Mechanism of tumourigenesis caused by loss of SMARCB1 in malignant rhabdoid tumors2014
Dr Rebecca Hill
Dr Janet Lindsey
Dr Ed Schwalbe
Dr Daniel Williamson
Dr Sarra Ryan
et al.
MYC and TP53 defects emerge and interact at medulloblastoma relapse, define rapidly progressive disease and can be targeted therapeutically2014
Dr Rebecca Hill
Dr Janet Lindsey
Dr Ed Schwalbe
Dr Karen Barker
Dr Daniel Williamson
et al.
MYC and TP53 defects interact at medulloblastoma relapse to define rapidly progressive disease and can be targeted therapeutically2014
Dr Martina Finetti
Matthew Selby
Alicia Del Carpio Pons
Ben Skalkoyannis
Amanda Smith
et al.
Next-generation sequencing identifies the mechanism of tumourigenesis caused by loss of SMARCB1 in malignant rhabdoid tumours2014
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Reza Rafiee
Dr Amir Enshaei
Sandeep Potluri
et al.
Routine molecular subgrouping of medulloblastoma: Bridging the divide between research and the clinic using low-cost DNA methylomics2014
Professor Steven Clifford
Dr Stephen Crosier
Sarah Nicholson
Dr Nicholas Bown
A national feasibility study of real-time central pathology review (CPR) and molecular diagnostics for medulloblastoma2013
Dr Stephen Crosier
Sarah Nicholson
Dr Nicholas Bown
Professor Steven Clifford
A National Feasibility Study of Real-Time Central Pathology Review and Molecular Diagnostics for Medulloblastoma2012
Dr Rachel Crossland
Dr Christine Challen
Dr Bridget Wilkins
Dr Stephen Crosier
Dr John Anderson
et al.
Definitive identification of the Val617Phe mutation in myeloproliferative disorders using Real Time PCR utilising Roche Lightcycler/hybriprobe technology2007
Dr John Anderson
Dr Stephen Crosier
Dr Jyotsna Shrimankar
Professor John Lunec
Dr Brian Angus
et al.
Downregulation of nuclear expression of the p33ING1b inhibitor of growth protein in invasive carcinoma of the breast2003
Dr Stephen Crosier
Dr Katrina Wood
Dr Philip Taylor
Professor Stephen Proctor
Dr Brian Angus
et al.
IAP survivin in diffuse large B cell lymphoma: Evaluation as a prognostic marker2003
Dr John Anderson
Dr Marie Mathers
Dr Niamh Leonard
Dr Stephen Crosier
Professor John Lunec
et al.
Nuclear to cytoplasmic compartment shift of the p33ING1b tumour suppressor protein is associated with malignancy in melanocytic lesions2002
Dr John Anderson
Dr Stephen Crosier
Dr Jyotsna Shrimankar
Professor John Lunec
Dr Brian Angus
et al.
p33ING1b tumour suppressor immunohistochemical expression in invasive breast carcinomas2002
Dr Stephen Crosier
Dr Brian Angus
Dr John Anderson
Use of transgenomic wave and denaturing gel electrophoresis increases the sensitivity of FR3A-FR4 PCR detection of B-cell clonality2002
Dr Stephen Crosier
Dr John Anderson
Dr Marie Mathers
Dr Niamh Leonard
Dr Stephen Crosier
et al.
p33(ING1b) tumour suppresser protein expression in melanocytic lesions, an immunohistochemical study of 67 cases2001
Dr John Anderson
Dr Stephen Crosier
Professor John Lunec
Dr Brian Angus
p33ING1b tumour suppresser protein expression in thyroid lesions determined by immunohistochemistry2001
Professor Christopher Eggett
Dr Stephen Crosier
Dr Philip Manning
Fiona Menzies
Emeritus Professor Calum McNeil
et al.
Development and characterisation of a glutamate-sensitive motor neurone cell line2000