Dr Ioana Cosgarea Dr Ashleigh McConnell Dr Tom Ewen Dr Diana Tang Dr David Hill et al. | Melanoma secretion of transforming growth factor-β2 leads to loss of epidermal AMBRA1 threatening epidermal integrity and facilitating tumour ulceration | 2022 |
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Dr Stamatina Verykiou Michael Alexander Dr Noel Edwards Professor Ruth Plummer Dr Bill Chaudhry et al. | Harnessing autophagy to overcome MEK-inhibitor induced resistance in metastatic melanoma | 2019 |
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Dr David Hill Dr Bill Chaudhry
| Embryonic zebrafish xenograft assay of human cancer metastasis | 2018 |
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Dr David Hill
| Cell cycle phase determines efficacy of bortezomib, temozolomide and MAPK inhibitor-induced apoptosis in melanoma | 2016 |
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Dr David Hill
| Cell Cycle Phase-Specific Drug Resistance as an Escape Mechanism of Melanoma Cells | 2016 |
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Dr David Hill Dr Fahad Ahmed
| MITF regulates cell adhesion and subcompartment-specific distribution of differentially cycling melanoma cells | 2016 |
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Dr David Hill Dr Jane Renwick Professor Penny Lovat
| A novel fully-humanised 3D skin equivalent to model early melanoma invasion | 2015 |
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Dr Jane Renwick Dr David Hill Christopher McKee Maria Anagnostou Fiyinfoluwa Babatunde et al. | Exploiting Cannabinoid-Induced Cytotoxic Autophagy to Drive Melanoma Cell Death | 2015 |
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Dr David Hill Professor Penny Lovat
| Making stressed melanoma self-destruct | 2015 |
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Dr David Hill Professor Penny Lovat
| Melanoma cells in G1 phase escape proteasome inhibitor cytotoxicity | 2015 |
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Dr David Hill Professor Penny Lovat
| Induction of endoplasmic reticulum stress as a strategy for melanoma therapy | 2014 |
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Dr David Hill Dr Stamatina Verykiou Dr Bill Chaudhry Professor Penny Lovat
| Modelling melanoma metastasis using organotypic skin equivalent and zebrafish models | 2014 |
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Dr David Hill
| Targeting the intrinsic apoptosis pathway as a strategy for melanoma therapy | 2014 |
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Christopher McKee Dr David Hill Dr Chris Redfern Dr Jane Armstrong Professor Penny Lovat et al. | Oncogenic BRAF signalling increases Mcl-1 expression in cutaneous metastatic melanoma | 2013 |
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Dr David Hill Professor Penny Lovat
| Optimization of endoplasmic reticulum (ER) stress-inducing therapies for melanoma using real-time cell cycle imaging | 2012 |
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Dr Jane Renwick Shaun Martin Dr David Hill Nicola Townshend Dr Chris Redfern et al. | Oncogenic B-RAF Signaling in Melanoma Impairs the Therapeutic Advantage of Autophagy Inhibition | 2011 |
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Shaun Martin Dr David Hill Professor Mark Birch-Machin Professor Penny Lovat Dr Chris Redfern et al. | Targeting GRP78 to enhance melanoma cell death | 2010 |
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Dr Emma Hiscutt Dr David Hill Shaun Martin Dr Andrew Harbottle Professor Mark Birch-Machin et al. | Targeting X-Linked Inhibitor of Apoptosis Protein to Increase the Efficacy of Endoplasmic Reticulum Stress-Induced Apoptosis for Melanoma Therapy | 2010 |
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Dr David Hill Shaun Martin Dr Jane Renwick Dr Ross Flockhart Dominic Simpson et al. | Combining the endoplasmic reticulum stress-inducing agents bortezomib and fenretinide as a novel therapeutic strategy for metastatic melanoma | 2009 |
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Professor Penny Lovat Dr Jane Renwick Shaun Martin Dr David Hill Dr Chris Redfern et al. | Increasing Melanoma Cell Death Using Inhibitors of Protein Disulphide Isomerases to Abrogate Survival Responses to Endoplasmic Reticulum Stress | 2009 |
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Dr Emma Hiscutt Dr David Hill Shaun Martin Dr Ross Flockhart Dr Jane Renwick et al. | Targeting XIAP to increase endoplasmic reticulum stress-induced apoptosis of malignant melanoma | 2009 |
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Dr David Hill Dr Jane Renwick Professor Mark Birch-Machin Professor Penny Lovat
| B-RAF signalling in endoplasmic reticulum stress-induced apoptosis of metastatic melanoma | 2008 |
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Shaun Martin Dr David Hill Dr Jane Renwick Professor Mark Birch-Machin Dr Chris Redfern et al. | Combining endoplasmic reticulum stress-inducing agents with protein disulphide isomerase inhibition: a novel therapeutic strategy for metastatic melanoma | 2008 |
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Professor Penny Lovat Dr Jane Renwick Shaun Martin Dr David Hill Professor Mark Birch-Machin et al. | Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress | 2008 |
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Dr David Hill Dr Jane Renwick Professor Mark Birch-Machin Professor Penny Lovat
| Defining the role of B-RAF-induced extracellular signal-related kinase in the resistance of metastatic melanoma to apoptosis | 2007 |
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Professor Penny Lovat Dr Jane Renwick Dr David Hill Professor Mark Birch-Machin Dr Chris Redfern et al. | Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: The role of stress proteins ERdj5 and ERp57 | 2007 |
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