Publications by Professor Penny Lovat - ePrints

Browsing publications by Professor Penny Lovat.

Newcastle Authors	Title	Year
Dr Krishan Mistry Grant Richardson Rob Smith Professor Penny Lovat	Porcine-derived collagen peptides promote re-epithelialisation through activation of integrin signalling	2024
Moyassar Al-Shaibani Dr Xiao Wang Dr Asif Tulah Dr Rachel Crossland Professor Anne Dickinson et al.	Role of mesenchymal stem cell conditioned medium on wound healing using a developed 3D skin model	2024
George Kelly Dr Tetsushi Kataura Dr Johan Panek Hanna Salmonowicz Hannah Kendall et al.	Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule	2024
Michael Alexander Will Cousins Dr Tom Ewen Professor Penny Lovat	The combined immunohistochemical expression of AMBRA1 and SQSTM1 identifies patients with poorly differentiated cutaneous squamous cell carcinoma at risk of metastasis: A proof of concept study	2024
Dr Tom Ewen Stuart Horswell Dr Helen Bosomworth Joe Lowenstein Grant Richardson et al.	Validation of epidermal AMBRA1 and loricrin (AMBLor) as a prognostic biomarker for nonulcerated American Joint Committee on Cancer stage I/II cutaneous melanoma	2024
Patience Kunonga Dr Ryan Kenny Margaret Astin Andrew Bryant Vasileios Kontogiannis et al.	Predictive accuracy of risk prediction models for recurrence, metastasis and survival for early-stage cutaneous melanoma: a systematic review	2023
Jing Lim Grace Mallett Dr David McDonald Dr Gill Hulme Dr Stephanie Laba et al.	Programmed cell death-1 receptor-mediated regulation of Tbet⁺NK1.1^- innate lymphoid cells within the tumor microenvironment	2023
Dr Francesco Zummo Merilin Georgiou Kirsty Cullen Minna Honkanen-Scott Professor James Shaw et al.	Exendin-4 stimulates autophagy in pancreatic β-cells via the RAPGEF/EPAC-Ca2+-PPP3/calcineurin-TFEB axis	2022
Jan Lecouturier Dr Helen Bosomworth Dr Marie Labus Dr Robert Ellis Professor Penny Lovat et al.	Health professional and patient views of a novel prognostic test for melanoma: A theoretically informed qualitative study	2022
Dr Ioana Cosgarea Dr Ashleigh McConnell Dr Tom Ewen Dr Diana Tang Dr David Hill et al.	Melanoma secretion of transforming growth factor-β2 leads to loss of epidermal AMBRA1 threatening epidermal integrity and facilitating tumour ulceration	2022
Dr Robert Ellis Benjamin Cosway Dr Marie Labus Professor Penny Lovat	HPV sensitizes OPSCC cells to cisplatin-induced apoptosis by inhibiting autophagy through E7-mediated degradation of AMBRA1	2021
Professor Luke Vale Patience Kunonga Dr Diarmuid Coughlan Vasileios Kontogiannis Margaret Astin et al.	Optimal surveillance strategies for Patients with stage 1 cutaneous melanoma post primary tumour excision: three systematic reviews and an economic model	2021
Krishan Mistry Tom Clifford Dr Marie Labus Professor Penny Lovat Dr Ashleigh McConnell et al.	Potentiating Cutaneous Wound Healing in Young and Aged Skin with Nutraceutical Collagen Peptides	2021
Tom Andrew Professor Penny Lovat	Predictive indicators for revisional surgery in nasal reconstruction after Mohs surgery	2021
Dr Robert Ellis Dr Diana Tang Dr Batoul Nasr Alison Greenwood Dr Ashleigh McConnell et al.	Epidermal autophagy and beclin 1 regulator 1 and loricrin: a paradigm shift in the prognostication and stratification of the American Joint Committee on Cancer stage I melanomas	2020
Dr Chiao-En Wu Tsin Koay Professor Penny Lovat Professor John Lunec	TP53 mutant cell lines selected for resistance to MDM2 inhibitors retain growth inhibition by MAPK pathway inhibitors but a reduced apoptotic response	2019
Dr Chiao-En Wu Tsin Koay Arman Esfandiari Professor Penny Lovat Professor John Lunec et al.	ATM Dependent DUSP6 Modulation of p53 Involved in Synergistic Targeting of MAPK and p53 Pathways with Trametinib and MDM2 Inhibitors in Cutaneous Melanoma	2019
Dr Stamatina Verykiou Michael Alexander Dr Noel Edwards Professor Ruth Plummer Dr Bill Chaudhry et al.	Harnessing autophagy to overcome MEK-inhibitor induced resistance in metastatic melanoma	2019
Patience Kunonga Margaret Astin Fiona Beyer Catherine Richmond Dr Wanwuri Akor et al.	Prognostic risk models following AJCC Stage 1 Melanoma: a systematic review	2019
Dr John Widdrington Dr Aurora Gomez Duran Dr Angela Pyle Dr Marie-Helene Ruchaud Jonathan Scott et al.	Exposure of Monocytic Cells to Lipopolysaccharide Induces Coordinated Endotoxin Tolerance, Mitochondrial Biogenesis, Mitophagy, and Antioxidant Defenses	2018
Arman Esfandiari Nan Wang Dr Ahmed Mahdi Erhan Aptullahoglu Professor Penny Lovat et al.	Targeting negative regulation of p53 by MDM2 and WIP1 as a therapeuticstrategy in cutaneous melanoma	2018
Dr Francesco Zummo Kirsty Cullen Minna Honkanen-Scott Professor James Shaw Professor Penny Lovat et al.	Glucagon-like peptide-1 protects pancreatic beta-cells from death by increasing autophagic flux and restoring lysosomal function	2017
Dr Bernadette Carroll Dr Glyn Nelson Dr Yoana Rabanal Ruiz Dr Olena Kucheryavenko Professor Penny Lovat et al.	Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing	2017
Dr Jane Renwick Christopher McKee Professor Penny Lovat	Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization.	2016
Dr Francesco Zummo Kirsty Cullen Professor Penny Lovat Professor James Shaw Dr Catherine Arden et al.	Glucagon-like peptide-1 requires EPAC activity to restore autophagy and protect pancreatic beta cells from cell death	2016
Professor Viktor Korolchuk Dr Bernadette Carroll Professor Penny Lovat Dr Nuria Martinez Lopez	Guidelines for the use and interpretation of assays for monitoring autophagy (3rd Ed.)	2016
Moyassar Al-Shaibani Dr Xiao Wang Professor Penny Lovat Professor Anne Dickinson	Mesenchymal stem cells promote wound healing via differentiation into epidermal keratinocyte-like cells	2016
Dr Diana Tang Dr Robert Ellis Professor Penny Lovat	Prognostic impact of autophagy biomarkers for cutaneous melanoma	2016
Dr Bernadette Carroll Dr Long Xie Professor Penny Lovat Professor Viktor Korolchuk	Targeting the persistent activation of mammalian target of rapamycin in BRAF mutated melanoma as a novel therapeutic strategy	2016
Professor Viktor Korolchuk Dr Bernadette Carroll Dr Long Xie Carola Dostal Professor Penny Lovat et al.	Targeting the persistent activation of mTOR in B-RAF and NRas mutated melanoma as a novel therapeutic strategy	2016
Emma Woodward Madona Elias Professor Penny Lovat Professor Nick Reynolds	TCDD-mediated induction of a chloracne phenotype is associated with aryl hydrocarbon receptor activation, deregulated epidermal differentiation, apoptosis and lysosomal processing	2016
Ashleigh McConnell Dr Robert Ellis Professor Ruth Plummer Professor Penny Lovat Dr Graeme O'Boyle et al.	The prognostic significance and impact of the CXCR4-CXCR7-CXCL12 axis in primary cutaneous melanoma	2016
Dr David Hill Dr Jane Renwick Professor Penny Lovat	A novel fully-humanised 3D skin equivalent to model early melanoma invasion	2015
Dr Francesco Zummo Kirsty Cullen Professor Penny Lovat Professor James Shaw Dr Catherine Arden et al.	An emerging role for autophagy in the regulation of beta cell survival by glucagon-like peptide-1	2015
Dr Stamatina Verykiou Professor Ruth Plummer Professor Penny Lovat	Contribution of autophagy to the survival of melanoma-initiating CD271-positive subpopulations	2015
Moyassar Al-Shaibani Dr Xiao Wang Professor Penny Lovat Professor Anne Dickinson	Deciphering the Role of Mesenchymal Stem Cells Paracrine in Wound Closure Acceleration	2015
Dr Jane Renwick Dr David Hill Christopher McKee Maria Anagnostou Fiyinfoluwa Babatunde et al.	Exploiting Cannabinoid-Induced Cytotoxic Autophagy to Drive Melanoma Cell Death	2015
David Hill Professor Penny Lovat	G1 phase melanoma cells escape proteasome inhibitor cytotoxicity	2015
Dr Francesco Zummo Kirsty Cullen Professor Penny Lovat Professor James Shaw Dr Catherine Arden et al.	Glucagon-like peptide 1 protects pancreatic beta cells from programmed cell death: a role for autophagy	2015
Dr David Hill Professor Penny Lovat	Making stressed melanoma self-destruct	2015
Dr David Hill Professor Penny Lovat	Melanoma cells in G1 phase escape proteasome inhibitor cytotoxicity	2015
Professor Penny Lovat	Oncogenic BRAF induces chronic ER stress condition resulting in increased basal autophagy and apoptotic resistance of cutaneous melanoma	2015
Ashleigh McConnell Dr Graeme O'Boyle Professor Matthew Wright Professor Penny Lovat	Targeting mitogen-activated protein kinase kinase to prevent CXCR₄-CXCL₁₂ chemotaxis in cutaneous melanoma	2015
Dr Bernadette Carroll Professor Penny Lovat Professor Viktor Korolchuk	Targeting the persistent activation of mammalian target of rapamycin in BRAF- and NRas-mutated melanoma as a novel therapeutic strategy	2015
Dr Robert Ellis Dr Stamatina Verykiou Maria Anagnostou Derek Hill Professor Penny Lovat et al.	Transforming growth factor-beta mediates loss of epidermal integrity and melanoma ulceration	2015
Shaun Martin Professor Penny Lovat Dr Chris Redfern	Cell-Type Variation in Stress Responses as a Consequence of Manipulating GRP78 Expression in Neuroectodermal Cells	2014
Dr Stamatina Verykiou Dr Robert Ellis Professor Penny Lovat	Established and Emerging Biomarkers in Cutaneous Malignant Melanoma	2014
Dr Nigel Kirkham Professor Penny Lovat Professor Neil Rajan	Increased p62 expression in CYLD-defective tumours: indication of an autophagic dependency?	2014
Dr David Hill Professor Penny Lovat	Induction of endoplasmic reticulum stress as a strategy for melanoma therapy	2014
Dr David Hill Dr Stamatina Verykiou Dr Bill Chaudhry Professor Penny Lovat	Modelling melanoma metastasis using organotypic skin equivalent and zebrafish models	2014
Maria Anagnostou Professor Penny Lovat Dr Robert Ellis	Proautophagic Ambra-1 as biomarker of differentiation in cutaneous squamous carcinoma	2014
Dr Robert Ellis Jonathan Lumsdon Dr Nigel Kirkham Dr Jane Renwick Professor Penny Lovat et al.	Prognostic Impact of p62 Expression in Cutaneous Malignant Melanoma	2014
Ashleigh McConnell Dr Robert Ellis Dr Graeme O'Boyle Professor Ruth Plummer Dr Stamatina Verykiou et al.	Prognostic significance of CXCR4 expression in cutaneous melanoma	2014
Dr Robert Ellis Maria Anagnostou Dr Stamatina Verykiou Martina Elias Dr Nigel Kirkham et al.	Transforming growth factor-beta-mediated Ambra-1 downregulation in melanoma ulceration and metastasis	2014
Professor Mark Birch-Machin Dr Robert Ellis Dr Jane Renwick Professor Penny Lovat	Increasing the therapeutic efficacy of docetaxel for cutaneous squamous cell carcinoma through the combined inhibition of phosphatidylinositol 3-kinase/AKT signalling and autophagy	2013
Shaun Martin Dr Heather Lamb Paul Thompson Professor Penny Lovat Professor Alastair Hawkins et al.	Inducing apoptosis of cancer cells using small-molecule plant compounds that bind to GRP78	2013
Dr Graeme O'Boyle Isabella Swidenbank Dr Helen Marshall Catriona Barker Dr Jane Renwick et al.	Inhibition of CXCR4-CXCL12 chemotaxis in melanoma by AMD11070	2013
Christopher McKee Dr David Hill Dr Chris Redfern Dr Jane Armstrong Professor Penny Lovat et al.	Oncogenic BRAF signalling increases Mcl-1 expression in cutaneous metastatic melanoma	2013
Dr Robert Ellis Dr Stamatina Verykiou Jonathan Lumsdon Dr Jane Renwick Dr Nigel Kirkham et al.	Peri-tumoural expression of pro-autophagic Ambra-1 as a prognostic biomarker for melanoma	2013
Dr David Hill Professor Penny Lovat	Optimization of endoplasmic reticulum (ER) stress-inducing therapies for melanoma using real-time cell cycle imaging	2012
Dr Robert Ellis Dr Jane Renwick Dr Nigel Kirkham Professor Penny Lovat	p62 as a biomarker of malignant melanoma	2012
Dr Robert Ellis Dr Jane Renwick Dr Nigel Kirkham Professor Penny Lovat	p62: a novel diagnostic and prognostic biomarker of malignant melanoma	2012
Dr Jane Renwick Shaun Martin Nicola Illingworth Dr David Jamieson Professor Penny Lovat et al.	The impact of retinoic acid treatment on the sensitivity of neuroblastoma cells to fenretinide	2012
Dr Jane Renwick Dr Robert Ellis Dr Nigel Kirkham Professor Penny Lovat	WIPI-1: a novel autophagy inhibitory protein in melanoma	2012
Dr Robert Ellis Dr Jane Renwick Christopher McKee Dr Nigel Kirkham Professor Penny Lovat et al.	Biomarkers of defective autophagy in melanoma	2011
Dr Jane Renwick Dr Robert Ellis Dr Nigel Kirkham Professor Penny Lovat	Defective autophagy in melanoma development and progression: role of oncogenic B-RAF signalling	2011
Dr Alison Forrester Professor Penny Lovat Professor Faith Williams Professor Nick Reynolds	Differential activation of the aryl hydrocarbon receptor and regulation of differentiation in the epidermal equivalent model	2011
Dr Jane Renwick Shaun Martin Dr David Hill Nicola Townshend Dr Chris Redfern et al.	Oncogenic B-RAF Signaling in Melanoma Impairs the Therapeutic Advantage of Autophagy Inhibition	2011
Dr Jane Renwick Dr Robert Ellis Professor Penny Lovat	Role of defective autophagy in melanoma development and progression: implication of oncogenic B-RAF signalling	2011
Christopher McKee Professor Penny Lovat Dr Jane Renwick	Role of Mcl-1 in the resistance of B-RAF mutated melanoma to autophagy	2011
Dr Jane Renwick Professor Penny Lovat	Oncogenic BRAF signalling confers resistance of metastatic melanoma to autophagy	2010
Dr Jane Renwick Dr Ross Flockhart Professor Gareth Veal Professor Penny Lovat Dr Chris Redfern et al.	Regulation of Endoplasmic Reticulum Stress-induced Cell Death by ATF4 in Neuroectodermal Tumor Cells	2010
Dr Robert Ellis Dr Emma Hiscutt Professor Penny Lovat Dr Jane Renwick	Role of Bcl-2 family proteins in oncogenic BRAF-induced resistance of melanoma to autophagy	2010
Shaun Martin Dr David Hill Professor Mark Birch-Machin Professor Penny Lovat Dr Chris Redfern et al.	Targeting GRP78 to enhance melanoma cell death	2010
Dr Emma Hiscutt Dr David Hill Shaun Martin Dr Andrew Harbottle Professor Mark Birch-Machin et al.	Targeting X-Linked Inhibitor of Apoptosis Protein to Increase the Efficacy of Endoplasmic Reticulum Stress-Induced Apoptosis for Melanoma Therapy	2010
Professor Penny Lovat Dr Ralph Jans	The antioxidant-response regulator Nrf2 is overexpressed in melanoma cells and further induced by oxidative stress - validation of Nrf2 as a novel adjuvant target for melanoma treatment	2010
Dr David Hill Shaun Martin Dr Jane Renwick Dr Ross Flockhart Dominic Simpson et al.	Combining the endoplasmic reticulum stress-inducing agents bortezomib and fenretinide as a novel therapeutic strategy for metastatic melanoma	2009
Professor Penny Lovat Dr Jane Renwick Shaun Martin Dr David Hill Dr Chris Redfern et al.	Increasing Melanoma Cell Death Using Inhibitors of Protein Disulphide Isomerases to Abrogate Survival Responses to Endoplasmic Reticulum Stress	2009
Professor Nick Reynolds Dr Ross Flockhart Dr Jane Renwick Professor Penny Lovat	NFAT signalling in metastatic melanoma: a novel target for oncogenic B-RAF	2009
Dr Ross Flockhart Dr Jane Renwick Professor Nick Reynolds Professor Penny Lovat	NFAT signalling is a novel target of oncogenic BRAF in metastatic melanoma	2009
Dr Emma Hiscutt Dr David Hill Shaun Martin Dr Ross Flockhart Dr Jane Renwick et al.	Targeting XIAP to increase endoplasmic reticulum stress-induced apoptosis of malignant melanoma	2009
Dr David Hill Dr Jane Renwick Professor Mark Birch-Machin Professor Penny Lovat	B-RAF signalling in endoplasmic reticulum stress-induced apoptosis of metastatic melanoma	2008
Shaun Martin Dr David Hill Dr Jane Renwick Professor Mark Birch-Machin Dr Chris Redfern et al.	Combining endoplasmic reticulum stress-inducing agents with protein disulphide isomerase inhibition: a novel therapeutic strategy for metastatic melanoma	2008
Professor Penny Lovat Shaun Martin Dr Jane Renwick Dr Chris Redfern Professor Mark Birch-Machin et al.	Combining ER-stress-induced apoptosis with protein disulphide isomerase inhibition as a novel therapeutic strategy for metastatic melanoma	2008
Diana Levett Shaun Martin Professor Penny Lovat Professor Mark Birch-Machin	Endoplasmic reticulum stress-induced apoptosis in response to imiquimod: a novel therapeutic strategy for metastatic squamous cell carcinoma?	2008
Dr Katrina Wood Dr Michael Jackson Dr Maria Lastowska Dr Darroch Hall Dr Helen Imrie et al.	Histological profile of tumours from MYCN transgenic mice	2008
Professor Penny Lovat Dr Jane Renwick Shaun Martin Dr David Hill Professor Mark Birch-Machin et al.	Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress	2008
Dr Ross Flockhart Professor Nick Reynolds Professor Penny Lovat	NFAT signalling in malignant melanoma	2008
Professor Penny Lovat Dr Chris Redfern Professor Mark Birch-Machin	Combining endoplasmic reticulum stress-inducing agents with protein disulphide isomerase inhibitors as a novel therapeutic strategy for metastatic melanoma	2007
Professor Penny Lovat Dr Chris Redfern Professor Mark Birch-Machin	Combining ER-stress inducing agents with protein disulphide inhibitors as a novel therapeutic strategy for metastatic melanoma	2007
Dr David Hill Dr Jane Renwick Professor Mark Birch-Machin Professor Penny Lovat	Defining the role of B-RAF-induced extracellular signal-related kinase in the resistance of metastatic melanoma to apoptosis	2007
Dr Jane Renwick Professor Gareth Veal Dr Chris Redfern Professor Penny Lovat	Role of Noxa in p53-independent fenretinide-induced apoptosis of neuroectodermal tumours	2007
Professor Penny Lovat Dr Jane Renwick Dr David Hill Professor Mark Birch-Machin Dr Chris Redfern et al.	Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: The role of stress proteins ERdj5 and ERp57	2007
Professor Penny Lovat Dr Andrew Harbottle Dr Chris Redfern Professor Mark Birch-Machin	Fenretinide-induced apoptosis via endoplasmic reticulum stress - new drug targets for melanoma therapy?	2006
Dr Emma Bell Dr Jane Carr-Wilkinson Dr Xiaohong Lu Professor Penny Lovat Professor John Lunec et al.	The role of MYCN in the failure of MYCN amplified neuroblastoma cell lines to G1 arrest after DNA damage	2006
Professor Penny Lovat Dr Chris Redfern	Fenretinide: A p53-independent way to kill cancer cells	2005
Dr Quentin Campbell Hewson Professor Penny Lovat Dr Jonathan Catterall Dr Chris Redfern	The NF-κB pathway mediates fenretinide-induced apoptosis in SH-SY5Y neuroblastoma cells	2005
Professor Penny Lovat Dr Chris Redfern	The role of gangliosides in fenretinide-induced apoptosis of neuroblastoma	2005
Professor Penny Lovat Professor Andrew Pearson Dr Andrew Hall Dr Chris Redfern	Gangliosides link the acidic sphingomyelinase-mediated induction of ceramide to 12-lipoxygenase-dependent apoptosis of neuroblastoma in response to fenretinide	2004
Professor Penny Lovat Bojidar Goranov Dr Chris Redfern	Molecular mechanisms of fenretinide-induced apoptosis of neuroblastoma cells	2004
Professor Penny Lovat Bojidar Goranov Dr Chris Redfern	Molecular mechanisms of fenretinide-induced apoptosis of neuroblastoma cells	2004
Professor Penny Lovat Bojidar Goranov Dr Chris Redfern	Bak: A Downstream Mediator of Fenretinide-Induced Apoptosis of SH-SY5Y Neuroblastoma Cells	2003
Professor Penny Lovat	Glucosylceramide synthase and its functional interaction with RTN-1C regulate chemotherapeutic-induced apoptosis in neuroepithelioma cells	2003
Professor Penny Lovat Professor Andrew Pearson Dr Chris Redfern	Growth and DNA Damage-Inducible Transcription Factor 153 Mediates Apoptosis in Response to Fenretinide but Not Synergy between Fenretinide and Chemotherapeutic Drugs in Neuroblastoma	2003
Professor Penny Lovat Professor Andrew Pearson Dr Chris Redfern	Induction of GADD153 and Bak: Novel molecular targets of fenretinide-induced apoptosis of neuroblastoma	2003
Professor Penny Lovat Professor Andrew Pearson Dr Chris Redfern	Mechanisms of free-radical induction in relation to fenretinide-induced apoptosis of neuroblastoma	2003
Professor Penny Lovat Dr Quentin Campbell Hewson Professor Andrew Pearson Dr Chris Redfern	GADD153 and 12-lipoxygenase mediate fenretinide-induced apoptosis of neuroblastoma	2002
Dr Quentin Campbell Hewson Professor Penny Lovat Professor Andrew Pearson Dr Chris Redfern	Retinoid signalling and gene expression in neuroblastoma cells: RXR agonist and antagonist effects on CRABP-II and RARβ expression	2002
Professor Penny Lovat Dr Chris Redfern Professor Andrew Pearson	Apoptosis in neuroblastomas induced by interferon-gamma involves the CD95/CD95L pathway	2001
Professor Penny Lovat Dr Mark Dobson Professor Archibald Malcolm Professor Andrew Pearson Dr Chris Redfern et al.	Differential gene regulation by 9-cis and all-trans retinoic acid in neuroblastoma cells	2001
Professor Penny Lovat Dr Michael Tilby Professor Archibald Malcolm Professor Andrew Pearson Dr Chris Redfern et al.	Distinct properties of fenretinide and CD437 lead to synergistic responses with chemotherapeutic reagents	2000
Professor Penny Lovat Professor Archibald Malcolm Professor Andrew Pearson Dr Chris Redfern	Effector mechanisms of fenretinide-induced apoptosis in neuroblastoma	2000
Dr Quentin Campbell Hewson Professor Penny Lovat Professor Archibald Malcolm Professor Andrew Pearson Dr Chris Redfern et al.	Receptor mechanisms mediating differentiation and proliferation effects of retinoids on neuroblastoma cells	2000
Professor Penny Lovat Dr Michael Tilby Professor Archibald Malcolm Professor Andrew Pearson Dr Chris Redfern et al.	Synergistic induction of apoptosis of neuroblastoma by fenretinide or CD437 in combination with chemotherapeutic drugs	2000
Professor Penny Lovat Dr Mark Dobson Professor Archibald Malcolm Professor Andrew Pearson Dr Chris Redfern et al.	Differential effects of retinoic acid isomers on the expression of nuclear receptor co-regulators in neuroblastoma	1999
Professor Penny Lovat Dr Chris Redfern Professor Andrew Pearson	Apoptosis in neuroblastomas induced by interferon-γ involves the CD95/CD95L pathway	1998
Professor Penny Lovat Dr Mark Dobson Professor Archibald Malcolm Professor Andrew Pearson Dr Chris Redfern et al.	Differential gene regulation by 9-cis and all-trans retinoic acid in neuroblastoma cells	1998
Professor Penny Lovat Dr Quentin Campbell Hewson Professor Archibald Malcolm Professor Andrew Pearson Dr Chris Redfern et al.	Retinoid-induced differentiation of neuroblastoma: Comparison between LG69, an RXR-selective analogue and 9-cis retinoic acid	1998
Professor Penny Lovat Professor Archibald Malcolm Professor Andrew Pearson Dr Chris Redfern	9-cis retinoic acid - A better retinoid for the modulation of differentiation, proliferation and gene expression in human neuroblastoma	1997
Professor Penny Lovat Professor Archibald Malcolm Professor Andrew Pearson Dr Chris Redfern	Apoptosis of N-type neuroblastoma cells after differentiation with 9- cis-retinoic acid and subsequent washout	1997
Professor Penny Lovat Professor Archibald Malcolm Professor Andrew Pearson Dr Chris Redfern	Retinoids in neuroblastoma therapy: Distinct biological properties of 9- cis- and all-trans-retinoic acid	1997
Dr Chris Redfern Professor Penny Lovat Professor Archibald Malcolm Professor Andrew Pearson	Gene expression and neuroblastoma cell differentiation in response to retinoic acid: differential effects of 9-cis and all-trans retinoic acid	1995
Professor Penny Lovat Professor Andrew Pearson Professor Archibald Malcolm Dr Chris Redfern	Concentration-dependent effects of 9-cis retinoic acid on neuroblastoma differentiation and proliferation in vitro	1994
Dr Chris Redfern Professor Penny Lovat Professor Archibald Malcolm Professor Andrew Pearson	Differential effects of 9-cis and all-trans retinoic acid on the induction of retinoic acid receptor-beta and cellular retinoic acid-binding protein II in human neuroblastoma cells	1994
Professor Penny Lovat Professor Andrew Pearson Professor Archibald Malcolm Dr Chris Redfern	Retinoic acid receptor expression during the in vitro differentiation of human neuroblastoma	1993