Dr Jane Renwick Christopher McKee Professor Penny Lovat
| Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization. | 2016 |
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Dr David Hill Dr Jane Renwick Professor Penny Lovat
| A novel fully-humanised 3D skin equivalent to model early melanoma invasion | 2015 |
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Dr Jane Renwick Dr David Hill Christopher McKee Maria Anagnostou Fiyinfoluwa Babatunde et al. | Exploiting Cannabinoid-Induced Cytotoxic Autophagy to Drive Melanoma Cell Death | 2015 |
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Dr Robert Ellis Jonathan Lumsdon Dr Nigel Kirkham Dr Jane Renwick Professor Penny Lovat et al. | Prognostic Impact of p62 Expression in Cutaneous Malignant Melanoma | 2014 |
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Professor Mark Birch-Machin Dr Robert Ellis Dr Jane Renwick Professor Penny Lovat
| Increasing the therapeutic efficacy of docetaxel for cutaneous squamous cell carcinoma through the combined inhibition of phosphatidylinositol 3-kinase/AKT signalling and autophagy | 2013 |
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Dr Graeme O'Boyle Isabella Swidenbank Dr Helen Marshall Catriona Barker Dr Jane Renwick et al. | Inhibition of CXCR4-CXCL12 chemotaxis in melanoma by AMD11070 | 2013 |
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Dr Robert Ellis Dr Stamatina Verykiou Jonathan Lumsdon Dr Jane Renwick Dr Nigel Kirkham et al. | Peri-tumoural expression of pro-autophagic Ambra-1 as a prognostic biomarker for melanoma | 2013 |
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Dr Caroline Bridgens Professor Gareth Veal Dr Chris Redfern Dr Jane Renwick
| Novel retinoic acid 4-hydroxylase (CYP26) inhibitors based on a 3-(1H-imidazol- and triazol-1-yl)-2,2-dimethyl-3-(4-(phenylamino)phenyl)propyl scaffold | 2012 |
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Dr Robert Ellis Dr Jane Renwick Dr Nigel Kirkham Professor Penny Lovat
| p62 as a biomarker of malignant melanoma | 2012 |
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Dr Robert Ellis Dr Jane Renwick Dr Nigel Kirkham Professor Penny Lovat
| p62: a novel diagnostic and prognostic biomarker of malignant melanoma | 2012 |
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Dr Caroline Bridgens Professor Gareth Veal Dr Chris Redfern Dr Jane Renwick
| Synthesis and CYP26A1 inhibitory activity of novel methyl 3-[4-(arylamino)phenyl]-3-(azole)-2,2-dimethylpropanoates | 2012 |
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Dr Jane Renwick Shaun Martin Nicola Illingworth Dr David Jamieson Professor Penny Lovat et al. | The impact of retinoic acid treatment on the sensitivity of neuroblastoma cells to fenretinide | 2012 |
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Dr Jane Renwick Dr Robert Ellis Dr Nigel Kirkham Professor Penny Lovat
| WIPI-1: a novel autophagy inhibitory protein in melanoma | 2012 |
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Dr Robert Ellis Dr Jane Renwick Christopher McKee Dr Nigel Kirkham Professor Penny Lovat et al. | Biomarkers of defective autophagy in melanoma | 2011 |
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Dr Jane Renwick Dr Robert Ellis Dr Nigel Kirkham Professor Penny Lovat
| Defective autophagy in melanoma development and progression: role of oncogenic B-RAF signalling | 2011 |
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Dr Jane Renwick Shaun Martin Dr David Hill Nicola Townshend Dr Chris Redfern et al. | Oncogenic B-RAF Signaling in Melanoma Impairs the Therapeutic Advantage of Autophagy Inhibition | 2011 |
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Dr Jane Renwick Dr Robert Ellis Professor Penny Lovat
| Role of defective autophagy in melanoma development and progression: implication of oncogenic B-RAF signalling | 2011 |
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Christopher McKee Professor Penny Lovat Dr Jane Renwick
| Role of Mcl-1 in the resistance of B-RAF mutated melanoma to autophagy | 2011 |
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Dr Caroline Bridgens Professor Gareth Veal Dr Chris Redfern Dr Jane Renwick
| Small Molecule Inhibitors of Retinoic Acid 4-Hydroxylase (CYP26): Synthesis and Biological Evaluation of Imidazole Methyl 3-(4-(aryl-2-ylamino)phenyl)propanoates | 2011 |
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Dr Caroline Bridgens Professor Gareth Veal Dr Chris Redfern Dr Jane Renwick
| Synthesis and Biological Evaluation of 3-(1H-Imidazol- and Triazol-1-yl)-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propyl Derivatives as Small Molecule Inhibitors of Retinoic Acid 4-Hydroxylase (CYP26) | 2011 |
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Dr Jane Renwick Professor Penny Lovat
| Oncogenic BRAF signalling confers resistance of metastatic melanoma to autophagy | 2010 |
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Dr Jane Renwick Dr Ross Flockhart Professor Gareth Veal Professor Penny Lovat Dr Chris Redfern et al. | Regulation of Endoplasmic Reticulum Stress-induced Cell Death by ATF4 in Neuroectodermal Tumor Cells | 2010 |
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Dr Robert Ellis Dr Emma Hiscutt Professor Penny Lovat Dr Jane Renwick
| Role of Bcl-2 family proteins in oncogenic BRAF-induced resistance of melanoma to autophagy | 2010 |
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Dr Emma Hiscutt Dr David Hill Shaun Martin Dr Andrew Harbottle Professor Mark Birch-Machin et al. | Targeting X-Linked Inhibitor of Apoptosis Protein to Increase the Efficacy of Endoplasmic Reticulum Stress-Induced Apoptosis for Melanoma Therapy | 2010 |
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Dr David Hill Shaun Martin Dr Jane Renwick Dr Ross Flockhart Dominic Simpson et al. | Combining the endoplasmic reticulum stress-inducing agents bortezomib and fenretinide as a novel therapeutic strategy for metastatic melanoma | 2009 |
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Professor Penny Lovat Dr Jane Renwick Shaun Martin Dr David Hill Dr Chris Redfern et al. | Increasing Melanoma Cell Death Using Inhibitors of Protein Disulphide Isomerases to Abrogate Survival Responses to Endoplasmic Reticulum Stress | 2009 |
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Professor Nick Reynolds Dr Ross Flockhart Dr Jane Renwick Professor Penny Lovat
| NFAT signalling in metastatic melanoma: a novel target for oncogenic B-RAF | 2009 |
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Dr Ross Flockhart Dr Jane Renwick Professor Nick Reynolds Professor Penny Lovat
| NFAT signalling is a novel target of oncogenic BRAF in metastatic melanoma | 2009 |
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Dr Emma Hiscutt Dr David Hill Shaun Martin Dr Ross Flockhart Dr Jane Renwick et al. | Targeting XIAP to increase endoplasmic reticulum stress-induced apoptosis of malignant melanoma | 2009 |
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Dr David Hill Dr Jane Renwick Professor Mark Birch-Machin Professor Penny Lovat
| B-RAF signalling in endoplasmic reticulum stress-induced apoptosis of metastatic melanoma | 2008 |
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Shaun Martin Dr David Hill Dr Jane Renwick Professor Mark Birch-Machin Dr Chris Redfern et al. | Combining endoplasmic reticulum stress-inducing agents with protein disulphide isomerase inhibition: a novel therapeutic strategy for metastatic melanoma | 2008 |
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Professor Penny Lovat Shaun Martin Dr Jane Renwick Dr Chris Redfern Professor Mark Birch-Machin et al. | Combining ER-stress-induced apoptosis with protein disulphide isomerase inhibition as a novel therapeutic strategy for metastatic melanoma | 2008 |
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Professor Penny Lovat Dr Jane Renwick Shaun Martin Dr David Hill Professor Mark Birch-Machin et al. | Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress | 2008 |
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Dr Jane Renwick Professor Gareth Veal Dr Chris Redfern
| Novel azolyl-(phenylmethyl)]aryl/heteroarylamines: Potent CYP26 inhibitors and enhancers of all-trans retinoic acid activity in neuroblastoma cells | 2008 |
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Dr David Hill Dr Jane Renwick Professor Mark Birch-Machin Professor Penny Lovat
| Defining the role of B-RAF-induced extracellular signal-related kinase in the resistance of metastatic melanoma to apoptosis | 2007 |
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Dr Jane Renwick Gordon Taylor Huw Thomas Professor Alan Boddy Dr Chris Redfern et al. | Molecular targeting of retinoic acid metabolism in neuroblastoma: The role of the CYP26 inhibitor R116010 in vitro and in vivo | 2007 |
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Dr Jane Renwick Professor Gareth Veal Dr Chris Redfern Professor Penny Lovat
| Role of Noxa in p53-independent fenretinide-induced apoptosis of neuroectodermal tumours | 2007 |
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Professor Penny Lovat Dr Jane Renwick Dr David Hill Professor Mark Birch-Machin Dr Chris Redfern et al. | Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: The role of stress proteins ERdj5 and ERp57 | 2007 |
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Dr Jane Renwick Dr Chris Redfern Professor Gareth Veal
| 13-cis Retinoic acid and isomerisation in paediatric oncology - Is changing shape the key to success? | 2005 |
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Dr Jane Renwick Professor Alan Boddy Dr Chris Redfern Professor Andrew Pearson Professor Gareth Veal et al. | Increasing the intracellular availability of all-trans retinoic acid in neuroblastoma cells | 2005 |
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Dr Reza Halse Dr Sylvie Bonavaud Dr Jane Renwick Emeritus Professor Steve Yeaman
| Control of glycogen synthesis by glucose, glycogen, and insulin in cultured human muscle cells | 2001 |
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Dr Jane Renwick Dr Sylvie Bonavaud Emeritus Professor Steve Yeaman
| Regulation of glycogen synthesis by amino acids in cultured human muscle cells | 2001 |
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Emeritus Professor Steve Yeaman Dr Jane Renwick Dr Sylvie Bonavaud Darren Poinasamy Dr Laura Rush et al. | Regulation of glycogen synthesis in human muscle cells | 2001 |
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