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Browsing publications by Dr Jane Renwick.

Newcastle AuthorsTitleYearFull text
Dr Jane Renwick
Christopher McKee
Professor Penny Lovat
Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization.2016
Dr David Hill
Dr Jane Renwick
Professor Penny Lovat
A novel fully-humanised 3D skin equivalent to model early melanoma invasion2015
Dr Jane Renwick
Dr David Hill
Christopher McKee
Maria Anagnostou
Fiyinfoluwa Babatunde
et al.
Exploiting Cannabinoid-Induced Cytotoxic Autophagy to Drive Melanoma Cell Death2015
Dr Robert Ellis
Jonathan Lumsdon
Dr Nigel Kirkham
Dr Jane Renwick
Professor Penny Lovat
et al.
Prognostic Impact of p62 Expression in Cutaneous Malignant Melanoma2014
Professor Mark Birch-Machin
Dr Robert Ellis
Dr Jane Renwick
Professor Penny Lovat
Increasing the therapeutic efficacy of docetaxel for cutaneous squamous cell carcinoma through the combined inhibition of phosphatidylinositol 3-kinase/AKT signalling and autophagy2013
Dr Graeme O'Boyle
Isabella Swidenbank
Dr Helen Marshall
Catriona Barker
Dr Jane Renwick
et al.
Inhibition of CXCR4-CXCL12 chemotaxis in melanoma by AMD110702013
Dr Robert Ellis
Dr Stamatina Verykiou
Jonathan Lumsdon
Dr Jane Renwick
Dr Nigel Kirkham
et al.
Peri-tumoural expression of pro-autophagic Ambra-1 as a prognostic biomarker for melanoma2013
Dr Caroline Bridgens
Professor Gareth Veal
Dr Chris Redfern
Dr Jane Renwick
Novel retinoic acid 4-hydroxylase (CYP26) inhibitors based on a 3-(1H-imidazol- and triazol-1-yl)-2,2-dimethyl-3-(4-(phenylamino)phenyl)propyl scaffold2012
Dr Robert Ellis
Dr Jane Renwick
Dr Nigel Kirkham
Professor Penny Lovat
p62 as a biomarker of malignant melanoma2012
Dr Robert Ellis
Dr Jane Renwick
Dr Nigel Kirkham
Professor Penny Lovat
p62: a novel diagnostic and prognostic biomarker of malignant melanoma2012
Dr Caroline Bridgens
Professor Gareth Veal
Dr Chris Redfern
Dr Jane Renwick
Synthesis and CYP26A1 inhibitory activity of novel methyl 3-[4-(arylamino)phenyl]-3-(azole)-2,2-dimethylpropanoates2012
Dr Jane Renwick
Shaun Martin
Nicola Illingworth
Dr David Jamieson
Professor Penny Lovat
et al.
The impact of retinoic acid treatment on the sensitivity of neuroblastoma cells to fenretinide2012
Dr Jane Renwick
Dr Robert Ellis
Dr Nigel Kirkham
Professor Penny Lovat
WIPI-1: a novel autophagy inhibitory protein in melanoma2012
Dr Robert Ellis
Dr Jane Renwick
Christopher McKee
Dr Nigel Kirkham
Professor Penny Lovat
et al.
Biomarkers of defective autophagy in melanoma2011
Dr Jane Renwick
Dr Robert Ellis
Dr Nigel Kirkham
Professor Penny Lovat
Defective autophagy in melanoma development and progression: role of oncogenic B-RAF signalling2011
Dr Jane Renwick
Shaun Martin
Dr David Hill
Nicola Townshend
Dr Chris Redfern
et al.
Oncogenic B-RAF Signaling in Melanoma Impairs the Therapeutic Advantage of Autophagy Inhibition2011
Dr Jane Renwick
Dr Robert Ellis
Professor Penny Lovat
Role of defective autophagy in melanoma development and progression: implication of oncogenic B-RAF signalling2011
Christopher McKee
Professor Penny Lovat
Dr Jane Renwick
Role of Mcl-1 in the resistance of B-RAF mutated melanoma to autophagy2011
Dr Caroline Bridgens
Professor Gareth Veal
Dr Chris Redfern
Dr Jane Renwick
Small Molecule Inhibitors of Retinoic Acid 4-Hydroxylase (CYP26): Synthesis and Biological Evaluation of Imidazole Methyl 3-(4-(aryl-2-ylamino)phenyl)propanoates2011
Dr Caroline Bridgens
Professor Gareth Veal
Dr Chris Redfern
Dr Jane Renwick
Synthesis and Biological Evaluation of 3-(1H-Imidazol- and Triazol-1-yl)-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propyl Derivatives as Small Molecule Inhibitors of Retinoic Acid 4-Hydroxylase (CYP26)2011
Dr Jane Renwick
Professor Penny Lovat
Oncogenic BRAF signalling confers resistance of metastatic melanoma to autophagy2010
Dr Jane Renwick
Dr Ross Flockhart
Professor Gareth Veal
Professor Penny Lovat
Dr Chris Redfern
et al.
Regulation of Endoplasmic Reticulum Stress-induced Cell Death by ATF4 in Neuroectodermal Tumor Cells2010
Dr Robert Ellis
Dr Emma Hiscutt
Professor Penny Lovat
Dr Jane Renwick
Role of Bcl-2 family proteins in oncogenic BRAF-induced resistance of melanoma to autophagy2010
Dr Emma Hiscutt
Dr David Hill
Shaun Martin
Dr Andrew Harbottle
Professor Mark Birch-Machin
et al.
Targeting X-Linked Inhibitor of Apoptosis Protein to Increase the Efficacy of Endoplasmic Reticulum Stress-Induced Apoptosis for Melanoma Therapy2010
Dr David Hill
Shaun Martin
Dr Jane Renwick
Dr Ross Flockhart
Dominic Simpson
et al.
Combining the endoplasmic reticulum stress-inducing agents bortezomib and fenretinide as a novel therapeutic strategy for metastatic melanoma2009
Professor Penny Lovat
Dr Jane Renwick
Shaun Martin
Dr David Hill
Dr Chris Redfern
et al.
Increasing Melanoma Cell Death Using Inhibitors of Protein Disulphide Isomerases to Abrogate Survival Responses to Endoplasmic Reticulum Stress2009
Professor Nick Reynolds
Dr Ross Flockhart
Dr Jane Renwick
Professor Penny Lovat
NFAT signalling in metastatic melanoma: a novel target for oncogenic B-RAF2009
Dr Ross Flockhart
Dr Jane Renwick
Professor Nick Reynolds
Professor Penny Lovat
NFAT signalling is a novel target of oncogenic BRAF in metastatic melanoma2009
Dr Emma Hiscutt
Dr David Hill
Shaun Martin
Dr Ross Flockhart
Dr Jane Renwick
et al.
Targeting XIAP to increase endoplasmic reticulum stress-induced apoptosis of malignant melanoma2009
Dr David Hill
Dr Jane Renwick
Professor Mark Birch-Machin
Professor Penny Lovat
B-RAF signalling in endoplasmic reticulum stress-induced apoptosis of metastatic melanoma2008
Shaun Martin
Dr David Hill
Dr Jane Renwick
Professor Mark Birch-Machin
Dr Chris Redfern
et al.
Combining endoplasmic reticulum stress-inducing agents with protein disulphide isomerase inhibition: a novel therapeutic strategy for metastatic melanoma2008
Professor Penny Lovat
Shaun Martin
Dr Jane Renwick
Dr Chris Redfern
Professor Mark Birch-Machin
et al.
Combining ER-stress-induced apoptosis with protein disulphide isomerase inhibition as a novel therapeutic strategy for metastatic melanoma2008
Professor Penny Lovat
Dr Jane Renwick
Shaun Martin
Dr David Hill
Professor Mark Birch-Machin
et al.
Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress2008
Dr Jane Renwick
Professor Gareth Veal
Dr Chris Redfern
Novel azolyl-(phenylmethyl)]aryl/heteroarylamines: Potent CYP26 inhibitors and enhancers of all-trans retinoic acid activity in neuroblastoma cells2008
Dr David Hill
Dr Jane Renwick
Professor Mark Birch-Machin
Professor Penny Lovat
Defining the role of B-RAF-induced extracellular signal-related kinase in the resistance of metastatic melanoma to apoptosis2007
Dr Jane Renwick
Gordon Taylor
Huw Thomas
Professor Alan Boddy
Dr Chris Redfern
et al.
Molecular targeting of retinoic acid metabolism in neuroblastoma: The role of the CYP26 inhibitor R116010 in vitro and in vivo2007
Dr Jane Renwick
Professor Gareth Veal
Dr Chris Redfern
Professor Penny Lovat
Role of Noxa in p53-independent fenretinide-induced apoptosis of neuroectodermal tumours2007
Professor Penny Lovat
Dr Jane Renwick
Dr David Hill
Professor Mark Birch-Machin
Dr Chris Redfern
et al.
Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: The role of stress proteins ERdj5 and ERp572007
Dr Jane Renwick
Dr Chris Redfern
Professor Gareth Veal
13-cis Retinoic acid and isomerisation in paediatric oncology - Is changing shape the key to success?2005
Dr Jane Renwick
Professor Alan Boddy
Dr Chris Redfern
Professor Andrew Pearson
Professor Gareth Veal
et al.
Increasing the intracellular availability of all-trans retinoic acid in neuroblastoma cells2005
Dr Reza Halse
Dr Sylvie Bonavaud
Dr Jane Renwick
Professor Steve Yeaman
Control of glycogen synthesis by glucose, glycogen, and insulin in cultured human muscle cells2001
Dr Jane Renwick
Dr Sylvie Bonavaud
Professor Steve Yeaman
Regulation of glycogen synthesis by amino acids in cultured human muscle cells2001
Professor Steve Yeaman
Dr Jane Renwick
Dr Sylvie Bonavaud
Darren Poinasamy
Dr Laura Rush
et al.
Regulation of glycogen synthesis in human muscle cells2001