Publications by Dr Patrick Yu Wai Man - ePrints

Browsing publications by Dr Patrick Yu Wai Man.

Newcastle Authors	Title	Year
Dr Tina Biss Dr Paul Brennan Philip Griffiths Professor Rita Horvath Professor Patrick Chinnery et al.	GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements	2022
George Cairns Dr Florence Burte Emily O'Connor Dr Angela Pyle Professor John Sayer et al.	A mutant wfs1 zebrafish model of Wolfram syndrome manifesting visual dysfunction and developmental delay	2021
Dr Patrick Yu Wai Man	Clinical utility gene card for: inherited optic neuropathies including next-generation sequencing-based approaches	2019
Dr Florence Burte Dr Patrick Yu Wai Man	Monoamine oxidase-A promotes protective autophagy in human SH-SY5Y neuroblastoma cells through Bcl-2 phosphorylation	2019
Selena Trifunov Dr Angela Pyle Dr Patrick Yu Wai Man Dr Florence Burte Dr Jennifer Duff et al.	Clonal expansion of mtDNA deletions: different disease models assessed by digital droplet PCR in single muscle cells	2018
Dr Patrick Yu Wai Man	GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes	2018
David Moore Dr Florence Burte Dr Patrick Yu Wai Man	A novel CISD2 mutation associated with a classical Wolfram syndrome phenotype alters Ca2+ homeostasis and ER-mitochondria interactions	2017
Professor Patrick Chinnery Dr Patrick Yu Wai Man	Childhood-onset Leber hereditary optic neuropathy	2017
Dr Patrick Yu Wai Man Professor Bobby McFarland	Common data elements for clinical research in mitochondrial disease: a National Institute for Neurological Disorders and Stroke project	2017
David Moore Dr Florence Burte Dr Patrick Yu Wai Man	Corrigendum: A novel CISD2 mutation associated with a classical wolfram syndrome phenotype alters Ca21 homeostasis and ER-mitochondria interactions. [Human Molecular Genetics (2017)], doi: 10.1093/hmg/ddx060	2017
Dr Patrick Yu Wai Man	Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations	2017
Dr Patrick Yu Wai Man	Erratum to: Genetic Counselling for Maternally Inherited Mitochondrial Disorders	2017
Dr Patrick Yu Wai Man David Moore Dr Florence Burte	Evaluating the therapeutic potential of idebenone and related quinone analogues in Leber hereditary optic neuropathy	2017
Dr Patrick Yu Wai Man	Genetic Counselling for Maternally Inherited Mitochondrial Disorders	2017
Dr Patrick Yu Wai Man	Harnessing the power of genetic engineering for patients with mitochondrial eye diseases	2017
Dr Valeria Chichagova Dr Dean Hallam Dr Joseph Collin Dr Adriana Buskin Dr Gabriele Saretzki et al.	Human iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243A>G mitochondrial DNA mutation	2017
Dr Patrick Yu Wai Man	Inherited eye-related disorders due to mitochondrial dysfunction	2017
Dr Patrick Yu Wai Man	Leber hereditary optic neuropathy: bridging the translational gap	2017
Dr Patrick Yu Wai Man	Management of ophthalmologic manifestations of mitochondrial diseases	2017
Dr Florence Burte Dr Dave Houghton Hannah Lowes Dr Angela Pyle Sarah Nesbitt et al.	Metabolic profiling of Parkinson's disease and mild cognitive impairment	2017
Dr Patrick Yu Wai Man	Monogenic diabetes syndromes: Locus-specific databases for Alström, Wolfram, and Thiamine-responsive megaloblastic anemia	2017
Professor Patrick Chinnery Dr Patrick Yu Wai Man	The pattern of retinal ganglion cell dysfunction in Leber hereditary optic neuropathy	2017
Dr Patrick Yu Wai Man	The Pattern of Retinal Ganglion Cell Loss in OPA1-Related Autosomal Dominant Optic Atrophy Inferred From Temporal, Spatial, and Chromatic Sensitivity Losses	2017
Dr Florence Burte Dr Patrick Yu Wai Man	CHCHD10 mutations promote loss of mitochondrial cristae junctions with impaired mitochondrial genome maintenance and inhibition of apoptosis	2016
Dr Patrick Yu Wai Man Dr Holly Duncan Dr Joseph Guadagno Professor Patrick Chinnery	A multiple sclerosis-like disorder in patients with OPA1 mutations	2016
Dr Patrick Yu Wai Man Dr Florence Burte	A neurodegenerative perspective on mitochondrial optic neuropathies	2016
Dr Peter Kullar Emerita Professor Janet Wilson Professor Rita Horvath Dr Patrick Yu Wai Man Professor Patrick Chinnery et al.	Both mitochondrial DNA and mitonuclear gene mutations cause hearing loss through cochlear dysfunction	2016
Dr Patrick Yu Wai Man	Clinical utility gene card for: Wolfram syndrome	2016
Marina Bartsakoulia Dr Juliane Mueller Dr Aurora Gomez Duran Dr Patrick Yu Wai Man Dr Veronika Boczonadi et al.	Cysteine Supplementation May be Beneficial in a Subgroup of Mitochondrial Translation Deficiencies	2016
Dr Grant Guthrie Dr Gerald Pfeffer Andrew Browning Professor Rita Horvath Professor Patrick Chinnery et al.	Erratum to: The neurological and ophthalmological manifestations of SPG4-related hereditary spastic paraplegia (vol 260, pg 906, 2013)	2016
Padraig Flannery Dr Florence Burte Professor Robert Taylor Professor Laurence Bindoff Dr Patrick Yu Wai Man et al.	Fatal infantile mitochondrial encephalomyopathy, hypertrophic cardiomyopathy and optic atrophy associated with a homozygous OPA1 mutation	2016
Dr Patrick Yu Wai Man	Genetic Manipulation for Inherited Neurodegenerative Diseases – Myth or Reality?	2016
Dr David Lewis-Smith Dr Helen Griffin Dr Jennifer Duff Dr Angela Pyle Professor Robert Taylor et al.	Homozygous deletion in MICU1 presenting with fatigue and lethargy in childhood	2016
Dr Holly Duncan Professor Patrick Chinnery Dr Patrick Yu Wai Man	Lamination of the Outer Plexiform Layer in Optic Atrophy Caused by Dominant WFS1 Mutations	2016
Dr Patrick Yu Wai Man Professor Patrick Chinnery	Leber Hereditary Optic Neuropathy	2016
Dr Patrick Yu Wai Man	Mitochondrial Optic Neuropathies - Clinical Manifestations and Natural History	2016
David Moore Dr Patrick Yu Wai Man	Reply: High prevalence of CHCHD10 mutations in patients with frontotemporal dementia from China	2016
Dr Patrick Yu Wai Man Professor Gavin Hudson Professor Patrick Chinnery	Reply: Parsing the differences in affected with LHON: genetic versus environmental triggers of disease conversion	2016
Dr Yi Ng Dr Patrick Yu Wai Man Professor Robert Taylor	The m.13051G > A mitochondrial DNA mutation results in variable neurology and activated mitophagy	2016
Dr Patrick Yu Wai Man Professor Patrick Chinnery	Autosomal Dominant Optic Atrophy	2015
Dr Patrick Yu Wai Man	Chronic Progressive External Ophthalmoplegia Secondary to Nuclear-Encoded Mitochondrial Genes	2015
Dr Florence Burte Professor Patrick Chinnery Dr Patrick Yu Wai Man	Disturbed mitochondrial dynamics and neurodegenerative disorders	2015
Dr Angela Pyle Tania Smertenko Dr David Bargiela Dr Helen Griffin Dr Jennifer Duff et al.	Exome sequencing in undiagnosed inherited and sporadic ataxias	2015
Professor Grainne Gorman Dr John Grady Dr Yi Ng Dr Andrew Schaefer Dr Richard McNally et al.	Mitochondrial Donation: How Many Women Could Benefit?	2015
Dr Patrick Yu Wai Man	Neuro-Ophthalmology in the United Kingdom	2015
Dr David Bargiela Dr Patrick Yu Wai Man Dr Michael Keogh Professor Rita Horvath Professor Patrick Chinnery et al.	Prevalence of neurogenetic disorders in the North of England	2015
Professor Grainne Gorman Dr Andrew Schaefer Dr Yi Ng Dr Charlotte Alston Catherine Feeney et al.	Prevalence of nuclear and mitochondrial DNA mutations related to adult mitochondrial disease	2015
David Moore Professor Patrick Chinnery Dr Patrick Yu Wai Man	Recessive Mutations in RTN4IP1 Cause Isolated and Syndromic Optic Neuropathies	2015
Dr Patrick Yu Wai Man	Reply: A distinct clinical phenotype in a German kindred with motor neuron disease carrying a CHCHD10 mutation	2015
Dr Patrick Yu Wai Man Professor Patrick Chinnery	Reply: 'Behr syndrome' with OPA1 compound heterozygote mutations	2015
Dr Patrick Yu Wai Man	Therapeutic Approaches to Inherited Optic Neuropathies	2015
Dr Patrick Yu Wai Man	Traumatic optic neuropathy-Clinical features and management issues	2015
Dr Patrick Yu Wai Man Professor Patrick Chinnery	197th ENMC international workshop: Neuromuscular disorders of mitochondrial fusion and fission-OPA1 and MFN2 molecular mechanisms and therapeutic strategies. 26-28 April 2013, Naarden, The Netherlands	2014
Dr Patrick Yu Wai Man Dr Angela Pyle Dr Helen Griffin Dr Mauro Santibanez Koref Professor Rita Horvath et al.	Abnormal retinal thickening is a common feature among patients with ARSACS-related phenotypes	2014
Professor Gavin Hudson Dr Angela Pyle Dr Patrick Yu Wai Man Professor Patrick Chinnery	Efficient mitochondrial biogenesis drives incomplete penetrance in Leber's hereditary optic neuropathy	2014
Dr Patrick Yu Wai Man Matthew Kirkman Professor Patrick Chinnery	Leber's hereditary optic neuropathy with late disease onset: clinical and molecular characteristics of 20 patients	2014
Dr Gerald Pfeffer Professor Grainne Gorman Dr Helen Griffin Dr Marzena Kurzawa-Akanbi Dr Ian Wilson et al.	Mutations in the SPG7 gene cause chronic progressive external ophthalmoplegia through disordered mitochondrial DNA maintenance	2014
David Moore Dr Patrick Yu Wai Man	Reply: Are CHCHD10 mutations indeed associated with familial amyotrophic lateral sclerosis?	2014
Dr Patrick Yu Wai Man Professor Patrick Chinnery	Reply: Early-onset Behr syndrome due to compound heterozygous mutations in OPA1	2014
David Moore Dr Patrick Yu Wai Man	Reply: Mutations in the CHCHD10 gene are a common cause of familial amyotrophic lateral sclerosis	2014
David Moore Dr Patrick Yu Wai Man	Reply: Two novel mutations in conserved codons indicate that CHCHD10 is a gene associated with motor neuron disease	2014
Dr Patrick Yu Wai Man Professor Patrick Chinnery	Treatment strategies for inherited optic neuropathies: past, present and future	2014
Philip Griffiths Dr Fiona Smith Dr Michael Firbank Professor Grainne Gorman Professor Robert Taylor et al.	Chronic progressive external ophthalmoplegia - Disease mechanisms and clinical outcome measures	2013
Dr Gerald Pfeffer Dr Ailbhe Burke Dr Patrick Yu Wai Man Professor Patrick Chinnery	Clinical features of MS associated with Leber hereditary optic neuropathy mtDNA mutations	2013
Dr Patrick Yu Wai Man Professor Patrick Chinnery	Defects in mitochondrial dynamics and mitochondrial DNA instability	2013
Dr Patrick Yu Wai Man Professor Patrick Chinnery	Dominant Optic Atrophy: Novel OPA1 Mutations and Revised Prevalence Estimates	2013
Dr Cynthia Yu Wai Man Dr Fiona Smith Dr Michael Firbank Professor Grainne Gorman Professor Robert Taylor et al.	Extraocular Muscle Atrophy and Central Nervous System Involvement in Chronic Progressive External Ophthalmoplegia	2013
Dr Patrick Yu Wai Man Nwanyieze Nwali Philip Griffiths Professor Patrick Chinnery	Idebenone treatment for Leber hereditary optic neuropathy - Past, present, and future	2013
Dr Angela Pyle Dr Helen Griffin Dr Jennifer Duff Shona Bennett Dr Simon Zwolinski et al.	Late-Onset Sacsinopathy Diagnosed by Exome Sequencing and Comparative Genomic Hybridization	2013
Professor Rita Horvath Dr Charlotte Alston Dr Patrick Yu Wai Man Dr Langping He Professor Robert Taylor et al.	Near-Identical Segregation of mtDNA Heteroplasmy in Blood, Muscle, Urinary Epithelium, and Hair Follicles in Twins With Optic Atrophy, Ptosis, and Intractable Epilepsy	2013
Dr Gerald Pfeffer Professor Rita Horvath Professor Laurence Bindoff Dr Patrick Yu Wai Man Professor Michael Hanna et al.	New treatments for mitochondrial disease - no time to drop our standards	2013
Dr Patrick Yu Wai Man Dr Bas Buchner Nwanyieze Nwali Philip Griffiths Professor Patrick Chinnery et al.	Persistence of the treatment effect of idebenone in Leber's hereditary optic neuropathy	2013
Anais Thouin Philip Griffiths Professor Gavin Hudson Professor Patrick Chinnery Dr Patrick Yu Wai Man et al.	Raised Intraocular Pressure as a Potential Risk Factor for Visual Loss in Leber Hereditary Optic Neuropathy	2013
Dr Kamil Sitarz Dr Angela Pyle Professor Rita Horvath Philip Griffiths Professor Patrick Chinnery et al.	Redefining Wolfram syndrome in the molecular Era	2013
Dr Patrick Yu Wai Man Professor Patrick Chinnery	Reply: Sensorineural hearing loss in OPA1-linked disorders	2013
Dr Patrick Yu Wai Man Philip Griffiths	Steroids for traumatic optic neuropathy	2013
Dr Patrick Yu Wai Man	The expanding clinical spectrum of dominant optic atrophy	2013
Dr Gerald Pfeffer Andrew Browning Professor Rita Horvath Professor Patrick Chinnery Dr Patrick Yu Wai Man et al.	The neurological and ophthalmological manifestations of SPG4-related hereditary spastic paraplegia	2013
Philip Griffiths Professor Patrick Chinnery Dr Patrick Yu Wai Man	Visual and psychological morbidity among patients with autosomal dominant optic atrophy	2013
Dr Kamil Sitarz Professor Rita Horvath Dr Angela Pyle Professor Robert Taylor Professor Patrick Chinnery et al.	OPA1 mutations induce mtDNA proliferation in leukocytes of patients with dominant optic atrophy	2012
Dr Patrick Yu Wai Man Professor Grainne Gorman Professor Robert Taylor Emeritus Professor Doug Turnbull	Diagnostic investigations of patients with chronic progressive external ophthalmoplegia	2012
Kamil Sitarz Professor Patrick Chinnery Dr Patrick Yu Wai Man	Disorders of the Optic Nerve in Mitochondrial Cytopathies: New Ideas on Pathogenesis and Therapeutic Targets	2012
Dr Patrick Yu Wai Man Professor Patrick Chinnery	Dysfunctional mitochondrial maintenance: what breaks the circle of life?	2012
Kamil Sitarz Dr Patrick Yu Wai Man Professor Gavin Hudson Professor Rita Horvath Professor Patrick Chinnery et al.	Genetic variations within the OPA1 gene are not associated with neuromyelitis optica	2012
Dr Patrick Yu Wai Man Professor Patrick Chinnery	Leber hereditary optic neuropathy – Therapeutic challenges and early promise	2012
Kamil Sitarz Dr Patrick Yu Wai Man Dr Angela Pyle Joanna Stewart Professor Rita Horvath et al.	MFN2 mutations cause compensatory mitochondrial DNA proliferation	2012
Dr Kamil Sitarz Dr Patrick Yu Wai Man Dr Angela Pyle Joanna Stewart Professor Rita Horvath et al.	MFN2 mutations cause compensatory mitochondrial DNA proliferation	2012
Dr Patrick Yu Wai Man	Mitochondrial Dysfunction in Glaucoma-Closing the Loop	2012
Dr Angela Pyle Dr Helen Griffin Dr Patrick Yu Wai Man Dr Jennifer Duff Gail Eglon et al.	Prominent Sensorimotor Neuropathy Due to SACS Mutations Revealed by Whole-Exome Sequencing	2012
Dr Patrick Yu Wai Man Professor Robert Taylor Professor Patrick Chinnery	Recessive spastic paraparesis associated with complex I deficiency due to MTHFR mutations	2012
Dr Brendan Payne Dr Ian Wilson Dr Patrick Yu Wai Man Dr Jonathan Coxhead Professor David Deehan et al.	Universal heteroplasmy of human mitochondrial DNA	2012
Dr Patrick Yu Wai Man Professor Patrick Chinnery	A randomised, placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy	2011
Dr Patrick Yu Wai Man Dr Sanatan Chattopadhyay Philip Griffiths Professor Patrick Chinnery	A randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy	2011
Dr Patrick Yu Wai Man	Genetic Screening for OPA1 and OPA3 Mutations in Patients with Suspected Inherited Optic Neuropathies	2011
Dr Patrick Yu Wai Man Professor Patrick Chinnery	Heterozygous OPA1 mutations in Behr syndrome [reply]	2011
Dr Patrick Yu Wai Man Professor Patrick Chinnery	Leber hereditary optic neuropathy – Therapeutic challenges and early promise	2011
Dr Patrick Yu Wai Man Philip Griffiths Professor Patrick Chinnery	Mitochondrial optic neuropathies - Disease mechanisms and therapeutic strategies	2011
Dr Patrick Yu Wai Man Professor Patrick Chinnery	OPA1 links human mitochondrial genome maintenance to mtDNA replication and distribution	2011
Dr Patrick Yu Wai Man Professor Mike Trenell Dr Kieren Hollingsworth Philip Griffiths Professor Patrick Chinnery et al.	OPA1 mutations impair mitochondrial function in both pure and complicated dominant optic atrophy	2011
Dr Patrick Yu Wai Man Professor Patrick Chinnery Philip Griffiths	Pattern of retinal ganglion cell loss in dominant optic atrophy due to OPA1 mutations	2011
Joanna Stewart Kamil Sitarz Professor Rita Horvath Dr Angela Pyle Dr Patrick Yu Wai Man et al.	POLG mutations cause decreased mitochondrial DNA repopulation rates following induced depletion in human fibroblasts	2011
Dr Patrick Yu Wai Man Professor Patrick Chinnery	Spastic paraplegia in 'dominant optic atrophy plus' phenotype due to OPA1 mutation [reply]	2011
Dr Patrick Yu Wai Man Philip Griffiths	Steroids for traumatic optic neuropathy	2011
Professor Mark Baker Dr Karen Fisher Professor Roger Whittaker Philip Griffiths Dr Patrick Yu Wai Man et al.	Subclinical multisystem neurologic disease in "pure" OPA1 autosomal dominant optic atrophy	2011
Professor Gavin Hudson Dr Patrick Yu Wai Man Philip Griffiths Professor Rita Horvath Professor Patrick Chinnery et al.	Variation in MAPT is not a contributing factor to the incomplete penetrance in LHON	2011
Dr Patrick Yu Wai Man Kamil Sitarz Dr David Samuels Philip Griffiths Dr Amy Reeve et al.	OPA1 mutations cause cytochrome c oxidase deficiency due to loss of wild-type mtDNA molecules	2010
Professor Laura Greaves Dr Patrick Yu Wai Man Kim Krishnan Nina Beadle Dr Martin Barron et al.	Mitochondrial DNA Defects and Selective Extraocular Muscle Involvement in CPEO	2010
Dr Patrick Yu Wai Man Philip Griffiths Professor Grainne Gorman Professor Roger Whittaker Professor Mark Baker et al.	Multi-system neurological disease is common in patients with OPA1 mutations	2010
Professor Patrick Chinnery Dr Matthew Jackson Dr Patrick Yu Wai Man Professor Grainne Gorman Michelle Baker et al.	Mutations in OPA1 expand the clinical phenotype of mitochondrial disease	2010
Dr Patrick Yu Wai Man Joanna Stewart Professor Gavin Hudson Dr Richard Andrews Philip Griffiths et al.	OPA1 increases the risk of normal but not high tension glaucoma	2010
Dr Patrick Yu Wai Man Dr Gillian Borthwick Dr Langping He Geoffrey Taylor Professor Laura Greaves et al.	Somatic Mitochondrial DNA Deletions Accumulate to High Levels in Aging Human Extraocular Muscles	2010
Dr Patrick Yu Wai Man Philip Griffiths Dr Ailbhe Burke Michael Clarke Professor Gavin Hudson et al.	The Prevalence and Natural History of Dominant Optic Atrophy Due to OPA1 Mutations	2010
Professor Gavin Hudson Dr Patrick Yu Wai Man Philip Griffiths Professor Patrick Chinnery	Variation in OPA1 does not explain the incomplete penetrance of Leber hereditary optic neuropathy	2010
Matthew Kirkman Dr Patrick Yu Wai Man Professor Patrick Chinnery	Gene-environment interactions in Leber hereditary optic neuropathy	2009
Professor Gavin Hudson Dr Patrick Yu Wai Man Professor Patrick Chinnery	Genetic variation in the methylenetetrahydrofolate reductase gene, MTHFR, does not alter the risk of visual failure in Leber's hereditary optic neuropathy	2009
Dr Patrick Yu Wai Man Professor Patrick Chinnery	Genomic rearrangements in OPA1 are frequent in patients with autosomal dominant optic atrophy	2009
Dr Patrick Yu Wai Man Philip Griffiths Professor Gavin Hudson Professor Patrick Chinnery	Inherited mitochondrial optic neuropathies	2009
Matthew Kirkman Philip Griffiths Professor Gavin Hudson Professor Patrick Chinnery Dr Patrick Yu Wai Man et al.	Quality of Life in Patients with Leber Hereditary Optic Neuropathy	2009
Dr Patrick Yu Wai Man Dr Lynsey Cree Professor Patrick Chinnery	Secondary mtDNA Defects Do Not Cause Optic Nerve Dysfunction in a Mouse Model of Dominant Optic Atrophy	2009
Dr Patrick Yu Wai Man Professor Patrick Chinnery	Subtle neurological and metabolic abnormalities in an Opa1 mouse model of autosomal dominant optic atrophy	2009
Dr Patrick Yu Wai Man Professor Grainne Gorman Dr David Bateman Professor Patrick Chinnery	Vertigo and vestibular abnormalities in spinocerebellar ataxia type 6	2009
Joanna Stewart Professor Gavin Hudson Dr Patrick Yu Wai Man Professor Rita Horvath Philip Griffiths et al.	OPA1 in multiple mitochondrial DNA deletion disorders	2008
Dr Patrick Yu Wai Man Stephen Morgan Anthony Hildreth Professor David Steel	Efficacy of intracameral and subconjunctival cefuroxime in preventing endophthalmitis after cataract surgery	2008
Dr Patrick Yu Wai Man Philip Griffiths Professor Patrick Chinnery	Investigation of auditory dysfunction in Leber hereditary optic neuropathy	2008
Professor Gavin Hudson Dr Patrick Yu Wai Man Professor Patrick Chinnery	Leber hereditary optic neuropathy	2008
Dr Patrick Yu Wai Man Dr David Bateman Professor Gavin Hudson Philip Griffiths Professor Patrick Chinnery et al.	Leber hereditary optic neuropathy presenting in a 75-year-old man	2008
Professor Gavin Hudson Dr Patrick Yu Wai Man Professor Rita Horvath Professor Bobby McFarland Emeritus Professor Doug Turnbull et al.	Mutations in OPA1 cause multiple mtDNA deletions: a novel disorder of mtDNA maintenance	2008
Matthew Kirkman Dr Patrick Yu Wai Man Professor Patrick Chinnery	The clinical spectrum of mitochondrial genetic disorders	2008
Matthew Kirkman Dr Patrick Yu Wai Man Professor Patrick Chinnery	The clinical spectrum of mitochondrial genetic disorders	2008
Professor Gavin Hudson Catherine Mowbray Dr Angela Pyle Dr Joanna Elson Philip Griffiths et al.	Clinical expression of Leber heriditary optic neuropathy is affected by the mitochondrial DNA-haplogroup background	2007
Dr Patrick Yu Wai Man Dr Margaret Dayan	Giant cell arteritis with normal inflammatory markers	2007
Dr Patrick Yu Wai Man Dr Douglas Crompton Dr Margaret Dayan	Optic perineuritis as a rare initial presentation of sarcoidosis	2007
Dr Patrick Yu Wai Man Philip Griffiths	Steroids for traumatic optic neuropathy	2007
Professor Gavin Hudson Dr Patrick Yu Wai Man Philip Griffiths Professor Rita Horvath Professor Patrick Chinnery et al.	Identification of an X-chromosomal locus and haplotype modulating the phenotype of a mitochondrial DNA disorder	2005
Dr Patrick Yu Wai Man Philip Griffiths	Surgery for traumatic optic neuropathy	2005
Dr Patrick Yu Wai Man Emeritus Professor Doug Turnbull Professor Patrick Chinnery	Mitochondrial DNA haplogroup distribution within Leber hereditary optic neuropathy pedigrees	2004
Professor Patrick Chinnery Dr Patrick Yu Wai Man	Pitfalls in restriction fragment length polymorphism analysis of Leber's hereditary optic neuropathy patients	2004
Dr Patrick Yu Wai Man Philip Griffiths Emeritus Professor Doug Turnbull Professor Patrick Chinnery	The epidemiology of Leber hereditary optic neuropathy in the North East of England	2003
Dr Patrick Yu Wai Man Dr Christopher Morris Emeritus Professor Doug Turnbull Professor Patrick Chinnery	The role of APOE in the phenotypic expression of Leber hereditary optic neuropathy	2003
Dr Patrick Yu Wai Man Emeritus Professor Doug Turnbull Professor Patrick Chinnery	Leber hereditary optic neuropathy	2002
Dr Patrick Yu Wai Man Emeritus Professor Doug Turnbull Professor Patrick Chinnery	NDUFA-1 is not a nuclear modifier gene in Leber hereditary optic neuropathy	2002