Publications by Philip Griffiths - ePrints

Browsing publications by Philip Griffiths.

Newcastle Authors	Title	Year
Dr Tina Biss Dr Paul Brennan Philip Griffiths Professor Rita Horvath Professor Patrick Chinnery et al.	GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements	2022
Philip Griffiths Dr Fiona Smith Dr Michael Firbank Professor Grainne Gorman Professor Robert Taylor et al.	Chronic progressive external ophthalmoplegia - Disease mechanisms and clinical outcome measures	2013
Dr Cynthia Yu Wai Man Dr Fiona Smith Dr Michael Firbank Professor Grainne Gorman Professor Robert Taylor et al.	Extraocular Muscle Atrophy and Central Nervous System Involvement in Chronic Progressive External Ophthalmoplegia	2013
Dr Patrick Yu Wai Man Nwanyieze Nwali Philip Griffiths Professor Patrick Chinnery	Idebenone treatment for Leber hereditary optic neuropathy - Past, present, and future	2013
Dr Patrick Yu Wai Man Dr Bas Buchner Nwanyieze Nwali Philip Griffiths Professor Patrick Chinnery et al.	Persistence of the treatment effect of idebenone in Leber's hereditary optic neuropathy	2013
Anais Thouin Philip Griffiths Professor Gavin Hudson Professor Patrick Chinnery Dr Patrick Yu Wai Man et al.	Raised Intraocular Pressure as a Potential Risk Factor for Visual Loss in Leber Hereditary Optic Neuropathy	2013
Dr Kamil Sitarz Dr Angela Pyle Professor Rita Horvath Philip Griffiths Professor Patrick Chinnery et al.	Redefining Wolfram syndrome in the molecular Era	2013
Dr Patrick Yu Wai Man Philip Griffiths	Steroids for traumatic optic neuropathy	2013
Philip Griffiths Professor Patrick Chinnery Dr Patrick Yu Wai Man	Visual and psychological morbidity among patients with autosomal dominant optic atrophy	2013
Dr Patrick Yu Wai Man Dr Sanatan Chattopadhyay Philip Griffiths Professor Patrick Chinnery	A randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy	2011
Philip Griffiths	A Supranuclear Disorder of Ocular Motility as a Rare Initial Presentation of Motor Neurone Disease	2011
Dr Patrick Yu Wai Man Philip Griffiths Professor Patrick Chinnery	Mitochondrial optic neuropathies - Disease mechanisms and therapeutic strategies	2011
Dr Patrick Yu Wai Man Professor Mike Trenell Dr Kieren Hollingsworth Philip Griffiths Professor Patrick Chinnery et al.	OPA1 mutations impair mitochondrial function in both pure and complicated dominant optic atrophy	2011
Dr Patrick Yu Wai Man Professor Patrick Chinnery Philip Griffiths	Pattern of retinal ganglion cell loss in dominant optic atrophy due to OPA1 mutations	2011
Dr Patrick Yu Wai Man Philip Griffiths	Steroids for traumatic optic neuropathy	2011
Professor Mark Baker Dr Karen Fisher Professor Roger Whittaker Philip Griffiths Dr Patrick Yu Wai Man et al.	Subclinical multisystem neurologic disease in "pure" OPA1 autosomal dominant optic atrophy	2011
Professor Gavin Hudson Dr Patrick Yu Wai Man Philip Griffiths Professor Rita Horvath Professor Patrick Chinnery et al.	Variation in MAPT is not a contributing factor to the incomplete penetrance in LHON	2011
Dr Patrick Yu Wai Man Kamil Sitarz Dr David Samuels Philip Griffiths Dr Amy Reeve et al.	OPA1 mutations cause cytochrome c oxidase deficiency due to loss of wild-type mtDNA molecules	2010
Philip Griffiths Professor Patrick Chinnery	Eye movement recordings to investigate a supranuclear component in chronic progressive external ophthalmoplegia: a cross-sectional study	2010
Professor Laura Greaves Dr Patrick Yu Wai Man Kim Krishnan Nina Beadle Dr Martin Barron et al.	Mitochondrial DNA Defects and Selective Extraocular Muscle Involvement in CPEO	2010
Dr Patrick Yu Wai Man Philip Griffiths Professor Grainne Gorman Professor Roger Whittaker Professor Mark Baker et al.	Multi-system neurological disease is common in patients with OPA1 mutations	2010
Dr Patrick Yu Wai Man Joanna Stewart Professor Gavin Hudson Dr Richard Andrews Philip Griffiths et al.	OPA1 increases the risk of normal but not high tension glaucoma	2010
Dr Patrick Yu Wai Man Dr Gillian Borthwick Dr Langping He Geoffrey Taylor Professor Laura Greaves et al.	Somatic Mitochondrial DNA Deletions Accumulate to High Levels in Aging Human Extraocular Muscles	2010
Dr Patrick Yu Wai Man Philip Griffiths Dr Ailbhe Burke Michael Clarke Professor Gavin Hudson et al.	The Prevalence and Natural History of Dominant Optic Atrophy Due to OPA1 Mutations	2010
Professor Gavin Hudson Dr Patrick Yu Wai Man Philip Griffiths Professor Patrick Chinnery	Variation in OPA1 does not explain the incomplete penetrance of Leber hereditary optic neuropathy	2010
Dr Patrick Yu Wai Man Philip Griffiths Professor Gavin Hudson Professor Patrick Chinnery	Inherited mitochondrial optic neuropathies	2009
Matthew Kirkman Philip Griffiths Professor Gavin Hudson Professor Patrick Chinnery Dr Patrick Yu Wai Man et al.	Quality of Life in Patients with Leber Hereditary Optic Neuropathy	2009
Joanna Stewart Professor Gavin Hudson Dr Patrick Yu Wai Man Professor Rita Horvath Philip Griffiths et al.	OPA1 in multiple mitochondrial DNA deletion disorders	2008
Professor Robert Taylor Professor Laura Greaves Dr Martin Barron Philip Griffiths Emeritus Professor Doug Turnbull et al.	A histochemical and molecular genetic investigation of the selective, extraocular muscle involvement in chronic progressive external ophthalmoplegia	2008
Dr Patrick Yu Wai Man Philip Griffiths Professor Patrick Chinnery	Investigation of auditory dysfunction in Leber hereditary optic neuropathy	2008
Dr Patrick Yu Wai Man Dr David Bateman Professor Gavin Hudson Philip Griffiths Professor Patrick Chinnery et al.	Leber hereditary optic neuropathy presenting in a 75-year-old man	2008
Professor Gavin Hudson Joanna Stewart Emeritus Professor Mike Sir Michael Rawlins Dr Andrew Schaefer Philip Griffiths et al.	Mutation of OPA1 causes dominant optic atrophy with external ophthalmoplegia, ataxia, deafness and multiple mitochondrial DNA deletions: A novel disorder of mtDNA maintenance	2008
Nicholas Wride Philip Griffiths Nicholas Strong Michael Clarke	Opaque intraocular lens for intractable diplopia: Experience and patients' expectations and satisfaction	2008
Professor Gavin Hudson Catherine Mowbray Dr Angela Pyle Dr Joanna Elson Philip Griffiths et al.	Clinical expression of Leber heriditary optic neuropathy is affected by the mitochondrial DNA-haplogroup background	2007
Dr Evelyn Jaros Dr Don Mahad Professor Gavin Hudson Dr Daniel Birchall Philip Griffiths et al.	Primary spinal cord neurodegeneration in Leber hereditary optic neuropathy	2007
Dr Patrick Yu Wai Man Philip Griffiths	Steroids for traumatic optic neuropathy	2007
Professor Patrick Chinnery Emeritus Professor Doug Turnbull Philip Griffiths	Assessment of visual function in chronic progressive external ophthalmoplegia	2006
Philip Griffiths Dr Adam Zermansky Professor David Burn	Characterising behavioural and cognitive dysexecutive changes in progressive supranuclear palsy: use of the Katz Adjustment Scale-Relatives (KAS-R)	2006
Philip Griffiths Dr Adam Zermansky Professor David Burn	Characterizing behavioral and cognitive dysexecutive changes in progressive supranuclear palsy	2006
Dr Richard Andrews Emeritus Professor Doug Turnbull Michael Birch Sharon Foster Professor Patrick Chinnery et al.	The role of mitochondrial haplogroups in primary open angle glaucoma	2006
Dr Ranjeet Pandit Dr Michael Snow Philip Griffiths	Unilateral recurrent acute retinal necrosis syndrome caused by cytomegalovirus in an immune-competent adult	2006
Philip Griffiths Sharon Foster Professor Patrick Chinnery Michael Birch	A polymorphism at codon 31 of gene p21 is not associated with primary open angle glaucoma in Caucasians	2005
Professor Patrick Chinnery Philip Griffiths	Extraocular muscles have fundamentally distinct properties that make them selectively vulnerable to certain disorders	2005
Professor Gavin Hudson Dr Patrick Yu Wai Man Philip Griffiths Professor Rita Horvath Professor Patrick Chinnery et al.	Identification of an X-chromosomal locus and haplotype modulating the phenotype of a mitochondrial DNA disorder	2005
Dr Terence Smith Dr Andrew Schaefer Emeritus Professor Doug Turnbull Philip Griffiths	Ocular motility findings in chronic progressive external ophthalmoplegia	2005
Dr Andrew Schaefer Philip Griffiths Emeritus Professor Doug Turnbull Professor Robert Taylor	Ophthalmoplegia due to mitochondrial DNA disease: The need for genetic diagnosis	2005
Professor Patrick Chinnery Philip Griffiths	Optic mitochondriopathies	2005
Dr Cynthia Yu Wai Man Professor Patrick Chinnery Philip Griffiths	Optic neuropathies - Importance of spatial distribution of mitochondria as well as function	2005
Dr Patrick Yu Wai Man Philip Griffiths	Surgery for traumatic optic neuropathy	2005
Dr Thomas Ressiniotis Philip Griffiths Dr Mark Birch Sharon Foster Professor Patrick Chinnery et al.	Apolipoprotein E promoter polymorphisms do not have a major influence on the risk of developing primary open angle glaucoma	2004
Philip Griffiths	Medically unexplained visual loss in adult patients	2004
Dr Ranjeet Pandit Philip Griffiths	Metastatic endogenous endophthalmitis secondary to Staphylococcus aureus iliopsoas abscess	2004
Dr Martin Barron Philip Griffiths Emeritus Professor Doug Turnbull	Mitochondria and the eye: ageing and disease	2004
Dr Andrew Schaefer Dr Martin Barron Philip Griffiths Professor Robert Taylor Emeritus Professor Doug Turnbull et al.	Ophthalmoplegia: When all the tests are negative	2004
Dr Sukhpal Sandhu Philip Griffiths Michael Birch	Optical coherence tomography scan acquisition protocol in assessing diabetic macular oedema in patients undergoing argon laser treatment	2004
Dr Thomas Ressiniotis Philip Griffiths Dr Mark Birch Sharon Foster Professor Patrick Chinnery et al.	Primary open angle glaucoma is associated with a specific p53 gene haplotype	2004
Dr Martin Barron Philip Griffiths Emeritus Professor Doug Turnbull Emeritus Professor David Bates Dr Philip Nichols et al.	The distributions of mitochondria and sodium channels reflect the specific energy requirements and conduction properties of the human optic nerve head	2004
Dr Thomas Ressiniotis Philip Griffiths Dr Mark Birch Sharon Foster Professor Patrick Chinnery et al.	The Role of Apolipoprotein E Gene Polymorphisms in Primary Open-angle Glaucoma	2004
Dr Thomas Ressiniotis Philip Griffiths Michael Birch Professor Patrick Chinnery	Apolipoprotein E gene polymorphisms in Primary Open Angle Glaucoma	2003
Philip Griffiths	Dying for drugs - Drug companies should not have to subsidise incompetent governments	2003
Zoe Johnson Philip Griffiths Michael Birch	Nurse prescribing in glaucoma	2003
Philip Griffiths Dr Andrew Schaefer Emeritus Professor Doug Turnbull	Ocular motility findings in chronic progressive external ophthalmoplegia	2003
Dr Patrick Yu Wai Man Philip Griffiths Emeritus Professor Doug Turnbull Professor Patrick Chinnery	The epidemiology of Leber hereditary optic neuropathy in the North East of England	2003
Philip Griffiths Dr Richard Andrews Emeritus Professor Doug Turnbull	The distribution of mitochondrial activity in relation to optic nerve structure	2002
Philip Griffiths Dr Martin Barron Dr Steve Durham Michael Clarke Emeritus Professor Doug Turnbull et al.	Distribution of mitochondrial dysfunction in ageing ocular tissues.	2001
Dr Ranjeet Pandit Philip Griffiths	Effectiveness of testing visual fields by confrontation	2001
Dr Martin Barron Dr Margaret Johnson Dr Richard Andrews Michael Clarke Philip Griffiths et al.	Mitochondrial abnormalities in ageing macular photoreceptors	2001
Philip Griffiths	Automated perimetry by optometrists in patients at low risk of glaucoma [Reply]	1999
Dr Richard Andrews Philip Griffiths Professor Patrick Chinnery Emeritus Professor Doug Turnbull	Evaluation of bupivacaine-induced muscle regeneration in the treatment of ptosis in patients with chronic progressive external ophthalmoplegia and Kearns-Sayre syndrome	1999
Dr Richard Andrews Philip Griffiths Dr Margaret Johnson Emeritus Professor Doug Turnbull	Histochemical localisation of mitochondrial enzyme activity in human optic nerve and retina	1999
Dr Richard Andrews Philip Griffiths Professor Patrick Chinnery Emeritus Professor Doug Turnbull	Mitochondrial DNA disease masquerading as age-related macular degeneration	1999
Philip Griffiths	Untitled	1999