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Browsing publications by Dr Christine Arris.

Newcastle AuthorsTitleYearFull text
Dr Ian Hardcastle
Dr Christine Arris
Dr Johanne Bentley
Professor Nicola Curtin
Professor Jane Endicott
et al.
N2-substituted O6-cyclohexylmethylguanine derivatives: Potent inhibitors of cyclin-dependent kinases 1 and 22004
Professor Nicola Curtin
Lan Wang
Suzanne Kyle
Dr Christine Arris
Professor barbara Durkacz
et al.
Novel Poly(ADP-ribose) Polymerase-1 Inhibitor, AG14361, Restores Sensitivity to Temozolomide in Mismatch Repair-Deficient Cells2004
Dr Veronique Mesguiche
Rachel Parsons
Dr Christine Arris
Dr Johanne Bentley
Professor Nicola Curtin
et al.
4-Alkoxy-2,6-diaminopyrimidine derivatives: Inhibitors of cyclin dependent kinases 1 and 22003
Stephen Walker
Dr Christine Arris
Dr John Taylor
Butyrate-mediated effects on Jurkat T-cells2003
Jeseem Mohamed
Dr Christine Arris
Michael Clarke
Professor Debra Bevitt
Expression of ADAMTS metalloproteinases in ARPE19 cells: Transcriptional regulation by TNF alpha2003
Professor Debra Bevitt
Dr Jonathan Catterall
Dr Christine Arris
Michael Clarke
Dr Norman Balfour-McKie
et al.
Expression of ADAMTS metalloproteinases in the retinal pigment epithelium derived cell line ARPE-19: Transcriptional regulation by TNF╬▒2003
Dr Christine Arris
Professor Debra Bevitt
Jeseem Mohamed
Michael Clarke
Expression of mutant and wild type TIMP3 in primary gingival fibroblasts from Sorsby's fundus dystrophy patients2003
Dr Christine Arris
Professor Debra Bevitt
Michael Clarke
Dr Norman Balfour-McKie
Expression of mutant and wild-type TIMP3 in primary gingival fibroblasts from Sorsby's fundus dystrophy patients2003
Noel Monks
Professor Nicola Curtin
Dr Christine Arris
Professor Herbie Newell
DNA interstrand cross-linking and TP53 status as determinants of tumour cell sensitivity in vitro to the antibody-directed enzyme prodrug therapy ZD27672002
Dr Ashleigh Gibson
Dr Christine Arris
Dr Johanne Bentley
Professor Nicola Curtin
Professor Jane Endicott
et al.
Probing the ATP ribose-binding domain of cyclin-dependent kinases 1 and 2 with O6-substituted guanine derivatives2002
Dr Johanne Bentley
Dr Christine Arris
Professor Nicola Curtin
Professor Jane Endicott
Dr Ashleigh Gibson
et al.
Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor2002
Professor Martin Noble
Dr Christine Arris
Professor Alan Calvert
Professor Nicola Curtin
Dr Ashleigh Gibson
et al.
Structural and thermodynamic validation of inactive cdk2 as a template for structure-based drug design2001
Professor Martin Noble
Dr Christine Arris
Professor Alan Calvert
Professor Nicola Curtin
Professor Bernard Golding
et al.
Structure based design of a potent inhibitor of cdk22001
Professor Roger Griffin
Dr Christine Arris
Professor Alan Calvert
Professor Nicola Curtin
Dr Ashleigh Gibson
et al.
Design, synthesis, and biological evaluation of O-6-alkylguanine and O-4-alkylpyrimidine cyclin-dependent kinase inhibitors2000
Dr Christine Arris
Professor Alan Calvert
Professor Nicola Curtin
Professor Jane Endicott
Professor Bernard Golding
et al.
Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles2000
Dr Christine Arris
Professor Alan Calvert
Professor Nicola Curtin
Dr Ashleigh Gibson
Professor Bernard Golding
et al.
Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles2000
Dr Christine Arris
Professor Alan Calvert
Professor Nicola Curtin
Professor Bernard Golding
Professor Roger Griffin
et al.
O6-substituted guanines and 4-substituted pyrimidines: a novel class of antiproliferative cyclin dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles.2000
Professor Roger Griffin
Dr Christine Arris
Dr Christine Bleasdale
Professor Alan Calvert
Professor Nicola Curtin
et al.
Resistance-modifying agents. 8. Inhibition of O6-alkylguanine-DNA alkyltransferase by O6-alkenyl-, O6-cycloalkenyl-, and O6-(2-oxoalkyl)guanines and potentiation of temozolomide cytotoxicity in vitro by O6-(1-cyclopentenylmethyl) guanine2000
Dr Johanne Bentley
Dr Christine Arris
Professor Alan Calvert
Professor Nicola Curtin
Professor Jane Endicott
et al.
Structure-activity relationships and cellular effects of novel purine- and pyrimidine-based cyclin dependent kinase inhibitors2000
Professor Herbie Newell
Dr Christine Arris
Professor Alan Calvert
Professor Nicola Curtin
Dr Ashleigh Gibson
et al.
Antiproliferative cyclin dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles.1999
Dr Christine Arris
Professor Alan Calvert
Professor Nicola Curtin
Dr Ashleigh Gibson
Professor Bernard Golding
et al.
In vitro growth activity of novel purine- and pyrimidine-based CDK1 and CDK2 inhibitors.1999
Dr Christine Arris
Dr Christine Bleasdale
Professor Alan Calvert
Professor Nicola Curtin
Professor Bernard Golding
et al.
Mechanism-based inhibition of O-6-methylguanine-DNA methyltransferase.1996
Dr Christine Arris
Dr Christine Bleasdale
Professor Alan Calvert
Professor Nicola Curtin
Professor Bernard Golding
et al.
Probing the active site and mechanism of action of O-6-methylguanine-DNA methyltransferase with substrate-analogs to (O-6-substituted guanines)1994