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Browsing publications by
Professor Jane Endicott
Newcastle Authors
Title
Year
Full text
Dr Ian Hope
Dr Mathew Martin
Dr Ziwei Jiang
Professor Mike Waring
Professor Martin Noble
et al.
Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction
2025
Dr Jessica Watt
Dr Mathew Martin
Professor Jane Endicott
Professor Martin Noble
Different applications and differentiated libraries for crystallographic fragment screening
2025
Dr Owen Burbidge
Dr Martyna Pastok
Dr Diana Papini
Kenneth Tan
Dr Shannon Turberville
et al.
Nanobodies restore stability to cancer-associated mutants of tumor suppressor protein p16INK4a
2025
Rhianna Rowland
Svitlana Korolchuk
Dr Marco Salamina
Dr Natalie Tatum
Professor Martin Noble
et al.
Cryo-EM structure of the CDK2-cyclin A-CDC25A complex
2024
Dr Celine Cano
Professor Jane Endicott
Dr Ian Hardcastle
Dr Claire Jennings
Suzanne Kyle
et al.
Discovery of ASTX295, a potent, next-generation small molecule antagonist of MDM2 with differentiated pharmacokinetic profile
2024
Dr Martyna Pastok
Dr Shannon Turberville
Dr Arnaud Basle
Professor Martin Noble
Professor Jane Endicott
et al.
Structural requirements for the specific binding of CRABP2 to cyclin D3
2024
Rhianna Rowland
Dr Richard Heath
Professor Jane Endicott
Professor Martin Noble
Dr Marco Salamina
Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1
2023
Dr Mathew Martin
Professor Jane Endicott
Professor Martin Noble
Dr Natalie Tatum
Crystallographic fragment screening in academic cancer drug discovery
2023
Svitlana Korolchuk
Professor Jane Endicott
Cyclin A and Cks1 promote kinase consensus switching to non-proline-directed CDK1 phosphorylation
2023
Dr Ian Hope
Professor Jane Endicott
Dr Jessica Watt
Emerging approaches to CDK inhibitor development, a structural perspective
2023
Gemma Davison
Dr Mathew Martin
Dr Shannon Turberville
Selma Dormen
Dr Richard Heath
et al.
Mapping ligand interactions of bromodomains BRD4 and ATAD2 with FragLites and PepLites ─ Halogenated probes of druglike and peptide-like molecular interactions
2022
Duncan Miller
Tristan Reuillon
Dr Lauren Molyneux
Dr Tim Blackburn
Dr Noel Edwards
et al.
Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain Inhibitor
2022
Islam Al-Khawaldeh
Dr Christine Basmadjian
Dr Cinzia Bordoni
Dr Suzannah Harnor
Amy Heptinstall
et al.
An alkynylpyrimidine-based covalent inhibitor that targets a unique cysteine in NF-κB-inducing kinase (NIK)
2021
Dr Marco Salamina
Dr Richard Heath
Svitlana Korolchuk
Dr Arnaud Basle
Dr Martyna Pastok
et al.
Discriminative SKP2 Interactions with CDK-Cyclin Complexes Support a Cyclin A-Specific Role in p27KIP1 Degradation
2021
Dr Natalie Tatum
Professor Jane Endicott
Chatterboxes: the structural and functional diversity of cyclins
2020
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