Publications by Professor Simi Ali - ePrints

Browsing publications by Professor Simi Ali.

Newcastle Authors	Title	Year
Dr Emily Thompson Chloe Connelly Professor Simi Ali Professor Neil Sheerin Colin Wilson et al.	Cell therapy during machine perfusion	2021
Irene del Molino del Barrio Dr Annette Meeson Katie Cooke Dr Imad Malki Dr Ben Barron-Millar et al.	Contribution of heparan sulphate binding in CCL21-mediated migration of breast cancer cells	2021
Emily Thompson Dr Avinash Sewpaul Lucy Bates Dr Sam Tingle Dr Aldi Situmorang et al.	MicroRNA antagonist therapy during normothermic machine perfusion of donor kidneys	2021
Nina Jordan Dr Sam Tingle Victoria Shuttleworth Katie Cooke Dr Rachael Redgrave et al.	MiR-126-3p Is Dynamically Regulated in Endothelial-to-Mesenchymal Transition during Fibrosis	2021
Dr Emily Thompson Lucy Bates Dr Ibrahim Ibrahim Dr Avinash Sewpaul Rodrigo Figueiredo et al.	Novel delivery of cellular therapy to reduce ischaemia reperfusion injury in kidney transplantation	2021
Dr Sarah Marsh Dr Catherine Park Dr Rachael Redgrave Dr Esha Singh Lilia Draganova et al.	Rapid fall in circulating non-classical monocytes in ST elevation myocardial infarction patients correlates with cardiac injury	2021
Dr Sam Tingle Dr Avinash Sewpaul Lucy Bates Dr Emily Thompson Victoria Shuttleworth et al.	Dual microRNA blockade increases expression of antioxidant protective proteins; implications for ischaemia reperfusion injury	2020
Dr Lu Wang Dr Guy MacGowan Professor Simi Ali Professor John Dark	Ex situ heart perfusion: The past, the present, and the future	2020
Jose Coelho Lima Junior Dr Ashfaq Mohammed Dr Suzanne Cormack Adnan Ali Dr Matthew Barter et al.	Kinetics Analysis of Circulating MicroRNAs Unveils Markers of Failed Myocardial Reperfusion	2020
Dr Bill Scott Dr Bill Scott III Professor Simi Ali Professor Andrew Fisher	Normothermic machine perfusion: a platform to assess and treat donor organs ex-situ with novel therapeutics prior to transplantation.	2020
Beatriz Martinez Burgo Professor John Kirby Professor Neil Sheerin Professor Simi Ali	A C-terminal CXCL8 peptide based on chemokine-glycosaminoglycan interactions reduces neutrophil adhesion and migration during inflammation	2019
Laura Ferreras Dr Anna Moles Fernandez Dr Aldi Situmorang Imogen Wilson Katie Cooke et al.	Heparan sulfate in chronic kidney diseases: exploring the role of 3-O-sulfation	2019
Shameem Sultanali Ladak Jason Powell Professor Andrew Fisher Professor Christopher Ward Professor Simi Ali et al.	The role of miR-200b-3p in modulating TGF-β1 induced injury in human bronchial epithelial cells	2019
Irene del Molino del Barrio Dr Georgie Wilkins Dr Annette Meeson Professor Simi Ali Professor John Kirby et al.	Breast Cancer: An Examination of the Potential of ACKR3 to Modify the Response of CXCR4 to CXCL12	2018
Dr Suzanne Cormack Samuel Jones Dr Rajiv Das Dr Mohaned Egred Professor Simi Ali et al.	Overcoming Heparin-Associated RT-qPCR Inhibition and Normalization Issues for microRNA Quantification in Patients with Acute Myocardial Infarction	2018
Emily Glover Nina Jordan Professor Neil Sheerin Professor Simi Ali	Regulation of Endothelial-to-Mesenchymal Transition by MicroRNAs in Chronic Allograft Dysfunction	2018
Adil Aldhahrani Jason Powell Shameem Sultanali Ladak Dr Mohammed Ali Professor Simi Ali et al.	The Potential Role of Bile Acids in Acquired Laryngotracheal Stenosis	2018
Dr Bakiah Shaharuddin Dr Sajjad Ahmad Dr Nani Md Latar Professor Simi Ali Dr Annette Meeson et al.	A Human Corneal Epithelial Cell Line Model for LimbalStem Cell Biology and Limbal Immunobiology	2017
Catriona Barker Sarah Thompson Dr Graeme O'Boyle Professor Neil Sheerin Professor Simi Ali et al.	CCL2 nitration is a negative regulator of chemokine-mediated inflammation	2017
Professor Simi Ali	Differential CCR7 targeting in Dendritic Cells by three naturally occurring CC-Chemokines (vol 7, 568, 2016)	2017
Anders Andreasson Danai Karamanou Dr Colin Gillespie Kasim Jiwa Dr Nicola Green et al.	Profiling inflammation and tissue injury markers in perfusate and bronchoalveolar lavage fluid during human ex vivo lung perfusion	2017
Sarah Thompson Beatriz Martinez Burgo Professor John Kirby Professor Neil Sheerin Professor Simi Ali et al.	Regulation of chemokine function: The roles of GAG-binding and post-translational nitration	2017
Anders Andreasson Dr Lee Borthwick Dr Colin Gillespie Kasim Jiwa Jonathan Scott et al.	The role of interleukin-1β as a predictive biomarker and potential therapeutic target during clinical ex vivo lung perfusion	2017
Dr Tarana Singh Dang Dr Joe Willet Helen Griffin Dr Graeme O'Boyle Dr Mario Abinun et al.	Defective Leukocyte Adhesion and Chemotaxis Contributes to Combined Immunodeficiency in Humans with Autosomal Recessive MST1 Deficiency	2016
Professor Simi Ali	Differential CCR7 Targeting in Dendritic Cells by Three Naturally Occurring CC-Chemokines	2016
Dr Tarana Singh Dang Dr Joe Willet Helen Griffin Dr Graeme O'Boyle Dr Mario Abinun et al.	Erratum to: Defective Leukocyte Adhesion and Chemotaxis Contributes to Combined Immunodeficiency in Humans with Autosomal Recessive MST1 Deficiency (vol 36, pg 117, 2016)	2016
Dr Bakiah Shaharuddin Dr Charles Osei-Bempong Professor Simi Ali Dr Rachel Oldershaw Dr Annette Meeson et al.	Human limbal mesenchymal stem cells express ABCB5 and can grow on amniotic membrane	2016
Beatriz Martinez Burgo Professor Simi Ali Jennifer Kirby Professor Neil Sheerin	Ischemia-Reperfusion Injury Following Transplantation: Implications for the Modulation of CXCL8 Chemokine Function.	2016
Shameem Sultanali Ladak Professor Christopher Ward Professor Simi Ali	MiRNA-200b Inhibits Epithelial-Mesenchymal Transition in TGF-b1 Induced Human Bronchial Epithelial Cells.	2016
Shameem Ladak Professor Christopher Ward Professor Simi Ali	The potential role of microRNAs in lung allograft rejection	2016
Professor John Kirby Professor Simi Ali	The Role of Chemokine and Glycosaminoglycan Interaction in Chemokine-Mediated Migration In Vitro and In Vivo	2016
Gabriel Cantanhede Dr Vaughan Carter Jennifer Kirby Professor Simi Ali	The Role of HLA Class II Antibody in Endothelial Cell Activation and Allograft Rejection	2016
Dr Anders Andreasson Danai Karamanou Dr Colin Gillespie Dr Lee Borthwick Kasim Jiwa et al.	Treating Donor Lung Inflammation by Blocking Interleukin-1B-An In Vitro Therapy Testing Platform for Ex Vivo Lung Perfusion	2016
Dr Gustavo Figueiredo Dr Jeffry Hogg Arthur Okonkwo Dr Deborah Stocken Professor Simi Ali et al.	Understanding ocular surface inflammation in tears before and after ex vivo expanded autologous limbal stem cell transplantation	2016
Professor Simi Ali	Glycosaminoglycan silencing by engineered CXCL12 variants	2015
Laura Ferreras Professor Neil Sheerin Professor John Kirby Professor Simi Ali	Mechanisms of renal graft chronic injury and progression to interstitial fibrosis	2015
Shameem Sultanali Ladak Professor Christopher Ward Professor Simi Ali	MicroRNA-200b represses TGF-β1 induced EMT in BEAS-2B and primary bronchial epithelial cells	2015
Dr Gustavo Figueiredo Professor Simi Ali Professor Francisco Figueiredo	Molecular analysis of inflammation in pannus tissue from patients with total limbal stem cell deficiency by quantitative real time PCR	2015
Stephen Douglass Dr Annette Meeson Dr Dorota Overbeck-Zubrzycka Dr John Brain Dr Chris Lamb et al.	Breast cancer metastasis: demonstration that FOXP3 regulates CXCR4 expression and the response to CXCL12	2014
Dr Bakiah Shaharuddin Ian Harvey Dr Sajjad Ahmad Professor Simi Ali Dr Annette Meeson et al.	Characterisation of Human Limbal Side Population Cells Isolated Using an Optimised Protocol From an Immortalised Epithelial Cell Line and Primary Limbal Cultures	2014
Professor Simi Ali	From di-peptides to whole proteins: exploiting peptide chemistry in the total synthesis of CCl2 and the rational design of new chemokine inhibitors	2014
Dr Bakiah Shaharuddin Professor Simi Ali Dr Annette Meeson	Limbal side population cells; a future treatment for limbal stem cell deficiency	2014
Sarah Thompson Dr Rachael Redgrave Professor John Kirby Professor Helen Arthur Professor Simi Ali et al.	Modulation of wound healing post-myocardial infarction	2014
Julia Spielhofer Professor John Kirby Professor Simi Ali	Role of 6-O-Sulfated Heparan Sulfate in Chronic Renal Fibrosis	2014
Shameem Sultanali Ladak Professor Simi Ali Professor Christopher Ward	The potential role of miRNA-200b in the development of Bronchiolitis obliterans syndrome	2014
Catriona Barker Professor Simi Ali Dr Graeme O'Boyle Professor John Kirby	Transplantation and inflammation: implications for the modification of chemokine function	2014
Fatmah Naemi Professor John Kirby Professor Simi Ali	Anti-Donor HLA Class I Antibodies: Pathways to Endothelial Cell Activation and Cell-Mediated Allograft Rejection	2013
Professor Simi Ali Professor Neil Sheerin	Biomarkers of acute injury: predicting the long-term outcome after transplantation	2013
Dr Graeme O'Boyle Professor Simi Ali Professor John Kirby	Comment on "CXCL19 causes heterologous desensitization of CXCL12-mediated memory T cell activation"	2013
Stephen Douglass Professor Simi Ali Dr Annette Meeson Professor John Kirby	Erratum to: The role of FOXP₃ in the development and metastatic spread of breast cancer (vol 31, pg 843, 2012)	2013
Professor John Kirby Professor Simi Ali	Evaluation of two cyclic di-peptides as inhibitors of CCL2 induced chemotaxis	2013
Professor John Kirby Professor Simi Ali	From Di-peptides to Whole Proteins: Exploiting Peptide Chemistry in the Rational Design of New Chemokine Inhibitors	2013
Professor Christopher Ward Professor Simi Ali	Identification of biomolecular marker of chronic lung allograft rejection	2013
Dr Bakiah Shaharuddin Dr Sajjad Ahmad Dr Annette Meeson Professor Simi Ali	Immunological Properties of Ocular Surface and Importance of Limbal Stem Cells for Transplantation	2013
Dr Joe Willet Dr Watchara Pichitsiri Dr Sarah Jenkinson Dr John Brain Dr Katrina Wood et al.	Kidney transplantation: analysis of the expression and T cell-mediated activation of latent TGF-β	2013
Arthur Okonkwo Shameem Sultanali Ladak Professor Simi Ali Professor John Kirby	Kidney transplantation: chronic molecular signatures in acute kidney injury	2013
Dr Bakiah Shaharuddin Dr Sajjad Ahmad Professor Simi Ali Dr Annette Meeson	Limbal Side Population cells: a future treatment for limbal stem cell deficiency	2013
Marcin Pekalski Dr Sarah Jenkinson Dr Joe Willet Dr Elizabeth Poyner Dr Helen Robertson et al.	Renal allograft rejection: Examination of delayed differentiation of Treg and Th17 effector T cells	2013
Eirini Giannoudaki Professor John Kirby Professor Simi Ali	Sphingosine 1-phosphate in ischemia-reperfusion injury: effects on trans-endothelial migration of neutrophils	2013
Professor John Kirby Professor Simi Ali	Antibody-Mediated Allograft Inflammation: A Study of Endothelial Cell Activation	2012
Dr Graeme O'Boyle Christopher Fox Dr Hannah Walden Dr Joe Willet Dr Emily Mavin et al.	Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation	2012
Fatmah Naemi Professor Simi Ali Professor John Kirby	HLA class I antibodies activate endothelial cells and UP-regulate adhesion molecules; a potential link between antibodies and cellular rejection	2012
Dr David Swan Professor John Kirby Professor Simi Ali	Post-Transplant Immunosuppression: Regulation of the Efflux of Allospecific Effector T Cells from Lymphoid Tissues	2012
Dr Emily Mavin Dr Shaheda Ahmed Dr Graeme O'Boyle Brie Turner Stephen Douglass et al.	Regulatory T Cells Inhibit CD8+ T-Cell Tissue Invasion in Human Skin Graft-Versus-Host Reactions	2012
Professor Simi Ali Professor John Dark Professor John Kirby	Strategies for inhibition of chemokine (CCL2) mediated monocyte migration in lethal reperfusion injury	2012
Professor Simi Ali Dr Annette Meeson Professor John Kirby	The role of FOXP3 in the development and metastatic spread of breast cancer	2012
Fatmah Naemi Professor Simi Ali Professor John Kirby	Antibody-mediated allograft rejection: The emerging role of endothelial cell signalling and transcription factors	2011
Xiaomeng Wang Brie Turner Dr Graeme O'Boyle Dr Saeed Ahmed Dr Emily Mavin et al.	Blocking effector T-cell trafficking contributes to regulatory T-cell mediated suppression of GvHD reactions	2011
Dr Graeme O'Boyle Professor Simi Ali Professor John Kirby	Chemokines in transplantation: what can atypical receptors teach us about anti-inflammatory therapy?	2011
Dr Dorota Overbeck-Zubrzycka Professor Simi Ali Professor John Kirby Professor Thomas Lennard	FOXP3 transcription factor regulates metastatic spread of breast cancer via control of expression of CXCR4 chemokine receptor	2011
Dr Graeme O'Boyle Professor Simi Ali Professor John Kirby	A strategy to inhibit effector T cell infiltration of allograft tissues by stimulation of the chemokine receptor CXCR3	2010
Dr Helen Marshall Dr Helen Robertson Professor John Kirby Professor Simi Ali Dr Graeme O'Boyle et al.	Cardiac Allograft Rejection: Examination of the Expression and Function of the Decoy Chemokine Receptor D6	2010
Professor John Dark Professor John Kirby Professor Simi Ali	Investigating the role of chemokine-mediated activation of VLA-4 and its function in leukocyte migration	2010
Dr David Swan Professor John Kirby Professor Simi Ali	Modulation of T lymphocyte responses to chemokines by sphingosine 1-phosphate	2010
Dr Watchara Pichitsiri Dr Joe Willet Dr Sarah Jenkinson Professor Simi Ali Professor John Kirby et al.	Renal allograft failure: can intragraft T cells activate latent TGF-beta?	2010
Julia Spielhofer Professor Simi Ali Professor John Kirby	Role of heparan sulphate 6-O sulphation in modulating FGF-2 signalling during chronic rejection	2010
Jonna Nilsson Professor Simi Ali Ian Harvey Professor John Kirby Dr Annette Meeson et al.	Stem cell therapy: a role for CXCR4 in homing bone marrow side population cells to areas of myocardial damage	2010
Fatmah Naemi Professor John Kirby Professor Simi Ali	The role of anti-HLA class I antibodies in graft outcome: rejection versus accommodation	2010
Professor Simi Ali Dr Graeme O'Boyle Philippa Hepplewhite Dr Helen Robertson Professor John Kirby et al.	Therapy with Nonglycosaminoglycan-Binding Mutant CCL7: A Novel Strategy to Limit Allograft Inflammation	2010
Dr David Swan Professor John Kirby Professor Simi Ali	Vascular biology: the role of sphingosine 1-phosphate in both the resting state and inflammation	2010
Dr Graeme O'Boyle Paul Mellor Professor John Kirby Professor Simi Ali	Anti-inflammatory therapy by intravenous delivery of non-heparan sulfate-binding CXCL12	2009
Professor Simi Ali Professor John Kirby Professor Thomas Lennard	Expression of FOXP3 in human breast cancer is inversely correlated with disease progression and the metastatic process: an immunohistochemical study	2009
Dr Graeme O'Boyle Professor Simi Ali Professor John Kirby	T cell extravasation: Demonstration of synergy between activation of CXCR3 and the T cell receptor	2009
abdul Al-Hamidi Marcin Pekalski Dr Helen Robertson Professor Simi Ali Professor John Kirby et al.	Chemokines have a potential role to modulate the adhesive function of CD103+T cells in renal allograft rejection	2008
Dr David Swan Dr Graeme O'Boyle Professor John Kirby Professor Simi Ali	Differential effects of S1P on responses to homeostatic versus inflammatory chemokines	2008
Professor Simi Ali Maureen Kirkley Professor John Kirby	Leukocyte extravasation: An immunoregulatory role for α-L-Fucosidase?	2008
Professor Simi Ali Professor John Kirby Professor Thomas Lennard	Mouse mammary tumor virus: a cause of breast cancer in humans?	2008
abdul Al-Hamidi Marcin Pekalski Dr Helen Robertson Professor Simi Ali Professor John Kirby et al.	Renal allograft rejection: The contribution of chemokines to the adhesion and retention of αE(CD103)β7 integrin-expressing intratubular T cells	2008
Professor Simi Ali Dr Graeme O'Boyle Paul Mellor Professor John Kirby	An apparent paradox: Chemokine receptor agonists can be used for anti-inflammatory therapy	2007
Dr Graeme O'Boyle Dr John Brain Professor John Kirby Professor Simi Ali	Chemokine-mediated inflammation: Identification of a possible regulatory role for CCR2	2007
Professor Simi Ali	Chemokines: Novel targets for breast cancer metastasis	2007
james Harvey Paul Mellor Professor Thomas Lennard Professor John Kirby Professor Simi Ali et al.	Inhibition of CXCR4-mediated breast cancer metastasis: A potential role for heparinoids?	2007
Paul Mellor james Harvey Dr Debbie Pye Dr Graeme O'Boyle Professor Thomas Lennard et al.	Modulatory effects of heparin and short-length oligosaccharides of heparin on the metastasis and growth of LMD MDA-MB 231 breast cancer cells in vivo	2007
Professor John Kirby Professor Simi Ali Professor Thomas Lennard	Role of the chemokine receptor CXCR4 in breast cancer metastasis	2007
Professor Simi Ali Dr Helen Robertson Professor John Isaacs Professor John Kirby	A non-glycosaminoglycan-binding variant of CC chemokine ligand 7 (monocyte chemoattractant protein-3) antagonizes chemokine-mediated inflammation	2005
Dr Graeme O'Boyle Professor John Kirby Professor Simi Ali	Differential chemokine signalling through CCR2	2005
james Harvey Professor Simi Ali Professor John Kirby Professor Thomas Lennard	Immunological prevention of breast cancer metastasis using heparins	2005
james Harvey Paul Mellor Professor Simi Ali Professor John Kirby Professor Thomas Lennard et al.	Low molecular weight heparins as inhibitors of carcinoma metastasis	2005
james Harvey Professor Simi Ali Professor John Kirby Professor Thomas Lennard	Low molecular weight heparins as inhibitors of carcinoma metastasis	2005
Professor Fiona Oakley Professor Jelena Mann Professor Simi Ali Professor Derek Mann	Nuclear Factor-κB1 (p50) Limits the Inflammatory and Fibrogenic Responses to Chronic Injury	2005
Professor Simi Ali Dr Ghada Malik Adam Burns Dr Helen Robertson Professor John Kirby et al.	Renal transplantation: Examination of the regulation of chemokine binding during acute rejection	2005
Dr Helen Robertson Professor Simi Ali Professor Alastair Burt Professor John Kirby	Chronic Renal Allograft Dysfunction: The Role of T Cell-Mediated Tubular Epithelial to Mesenchymal Cell Transition	2004
Dr Lynne Hardy Dr Trevor Booth Professor Simi Ali Professor John Kirby	Examination of MCP-1 (CCL2) partitioning and presentation during transendothelial leukocyte migration	2004
Professor Simi Ali Professor John Kirby	Endothelial inflammation: the role of differential expression of N-deacetylase/N-sulphotransferase enzymes in alteration of the immunological properties of heparan sulphate	2003
Professor Simi Ali Professor John Kirby	Endothelial inflammation: The role of differential expression of N-deacetylease/N-sulphotransferase enzymes in alteration of the immunological properties of heparan sulphate	2003
Professor Simi Ali Professor John Kirby Emeritus Professor Paul Flecknell Professor John Dark	Improvements in lung compliance after pulmonary transplantation: Correlation with interleukin 8 expression	2003
Professor Simi Ali Louise Hardy Professor John Kirby	Transplant immunobiology: A crucial role for heparan sulfate glycosaminoglycans?	2003
Dr Helen Robertson Helen Carroll Professor Simi Ali Professor John Kirby	Tubulitis in renal allograft rejection: role of TGFb and IL-15 in development and maintenance of CD103+T cells	2003
Dr Helen Robertson Helen Carroll Professor Simi Ali Professor John Kirby	Tubulitis in renal allograft rejection: Role of transforming growth factor-β and interleukin-15 in development and maintenance of CD103+ intraepithelial T cells	2003
Professor Simi Ali Sarah Fritchley Dr Benjamin Chaffey Professor John Kirby	Contribution of the putative heparan sulfate-binding motif BBXB of RANTES to transendothelial migration	2002
Julie Wain Professor John Kirby Professor Simi Ali	Leucocyte chemotaxis: Examination of mitogen-activated protein kinase and phosphoinositide 3-kinase activation by Monocyte Chemoattractant Proteins-1, -2, -3 and -4	2002
Professor Simi Ali Professor John Kirby	Accelerating the induction of Fas-mediated T cell apoptosis: A strategy for transplant tolerance?	2001
Professor Simi Ali Dr Adrian Palmer Sarah Fritchley Yvonne Maley Professor John Kirby et al.	Multimerization of monocyte chemoattractant protein-1 is not required for glycosaminoglycan-dependent transendothelial chemotaxis	2001
Michelle Dowsland Professor Simi Ali Professor John Kirby Professor Thomas Lennard	TNF-alpha affects CXCR4 gene expression and apoptosis in the breast cancer cell line MCF-7.	2001
Professor Simi Ali Dr Adrian Palmer Sarah Fritchley Professor John Kirby	Examination of the function of RANTES, MIP-1α, and MIP-1β following interaction with heparin-like glycosaminoglycans	2000
Sarah Fritchley Professor John Kirby Professor Simi Ali	The antagonism of interferon-gamma (IFN-γ) by heparin: Examination of the blockade of class II MHC antigen and heat shock protein-70 expression	2000
Professor Derek Manas Professor Simi Ali Professor John Kirby David Talbot	The impact of cytomegalovirus serology for 7-year graft survival in cadaveric kidney transplantation - The Newcastle experience	2000
Professor Simi Ali Emeritus Professor Harry Gilbert Emeritus Professor Barry Hirst Dr Judith Hall	Bacterial xylanase expression in mammalian cells and transgenic mice	1999
Professor Simi Ali Emmett O'Flaherty Thomas Griffiths Professor David Neal Professor John Kirby et al.	Bladder cancer immunogenicity: expression of CD80 and CD86 is insufficient to allow primary CD4(+) T cell activation in vitro	1999
Professor Simi Ali Thomas Griffiths Professor David Neal Professor John Kirby	Bladder cancer immunogenicity: expression of CD80 and CD86 is insufficient to allow primary CD4+T cell activation in vitro	1999