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Browsing publications by Professor Simi Ali.

Newcastle AuthorsTitleYearFull text
Dr Emily Thompson
Chloe Connelly
Professor Simi Ali
Professor Neil Sheerin
Colin Wilson
et al.
Cell therapy during machine perfusion2021
Irene del Molino del Barrio
Dr Annette Meeson
Katie Cooke
Dr Imad Malki
Dr Ben Barron-Millar
et al.
Contribution of heparan sulphate binding in CCL21-mediated migration of breast cancer cells2021
Emily Thompson
Dr Avinash Sewpaul
Lucy Bates
Dr Sam Tingle
Dr Aldi Situmorang
et al.
MicroRNA antagonist therapy during normothermic machine perfusion of donor kidneys 2021
Nina Jordan
Dr Sam Tingle
Victoria Shuttleworth
Katie Cooke
Dr Rachael Redgrave
et al.
MiR-126-3p Is Dynamically Regulated in Endothelial-to-Mesenchymal Transition during Fibrosis2021
Dr Emily Thompson
Lucy Bates
Dr Ibrahim Ibrahim
Dr Avinash Sewpaul
Rodrigo Figueiredo
et al.
Novel delivery of cellular therapy to reduce ischaemia reperfusion injury in kidney transplantation2021
Dr Sarah Marsh
Dr Catherine Park
Dr Rachael Redgrave
Dr Esha Singh
Lilia Draganova
et al.
Rapid fall in circulating non-classical monocytes in ST elevation myocardial infarction patients correlates with cardiac injury2021
Dr Sam Tingle
Dr Avinash Sewpaul
Lucy Bates
Dr Emily Thompson
Victoria Shuttleworth
et al.
Dual microRNA blockade increases expression of antioxidant protective proteins; implications for ischaemia reperfusion injury2020
Dr Lu Wang
Dr Guy MacGowan
Professor Simi Ali
Professor John Dark
Ex situ heart perfusion: The past, the present, and the future2020
Jose Coelho Lima Junior
Dr Ashfaq Mohammed
Dr Suzanne Cormack
Adnan Ali
Dr Matthew Barter
et al.
Kinetics Analysis of Circulating MicroRNAs Unveils Markers of Failed Myocardial Reperfusion2020
Dr Bill Scott
Dr Bill Scott III
Professor Simi Ali
Professor Andrew Fisher
Normothermic machine perfusion: a platform to assess and treat donor organs ex-situ with novel therapeutics prior to transplantation.2020
Beatriz Martinez Burgo
Professor John Kirby
Professor Neil Sheerin
Professor Simi Ali
A C-terminal CXCL8 peptide based on chemokine-glycosaminoglycan interactions reduces neutrophil adhesion and migration during inflammation2019
Laura Ferreras
Dr Anna Moles Fernandez
Dr Aldi Situmorang
Imogen Wilson
Katie Cooke
et al.
Heparan sulfate in chronic kidney diseases: exploring the role of 3-O-sulfation2019
Shameem Sultanali Ladak
Jason Powell
Professor Andrew Fisher
Professor Christopher Ward
Professor Simi Ali
et al.
The role of miR-200b-3p in modulating TGF-β1 induced injury in human bronchial epithelial cells2019
Irene del Molino del Barrio
Dr Georgie Wilkins
Dr Annette Meeson
Professor Simi Ali
Professor John Kirby
et al.
Breast Cancer: An Examination of the Potential of ACKR3 to Modify the Response of CXCR4 to CXCL122018
Dr Suzanne Cormack
Samuel Jones
Dr Rajiv Das
Dr Mohaned Egred
Professor Simi Ali
et al.
Overcoming Heparin-Associated RT-qPCR Inhibition and Normalization Issues for microRNA Quantification in Patients with Acute Myocardial Infarction2018
Emily Glover
Nina Jordan
Professor Neil Sheerin
Professor Simi Ali
Regulation of Endothelial-to-Mesenchymal Transition by MicroRNAs in Chronic Allograft Dysfunction2018
Adil Aldhahrani
Jason Powell
Shameem Sultanali Ladak
Dr Mohammed Ali
Professor Simi Ali
et al.
The Potential Role of Bile Acids in Acquired Laryngotracheal Stenosis2018
Dr Bakiah Shaharuddin
Dr Sajjad Ahmad
Dr Nani Md Latar
Professor Simi Ali
Dr Annette Meeson
et al.
A Human Corneal Epithelial Cell Line Model for LimbalStem Cell Biology and Limbal Immunobiology2017
Catriona Barker
Sarah Thompson
Dr Graeme O'Boyle
Professor Neil Sheerin
Professor Simi Ali
et al.
CCL2 nitration is a negative regulator of chemokine-mediated inflammation2017
Professor Simi Ali
Differential CCR7 targeting in Dendritic Cells by three naturally occurring CC-Chemokines (vol 7, 568, 2016)2017
Anders Andreasson
Danai Karamanou
Dr Colin Gillespie
Kasim Jiwa
Dr Nicola Green
et al.
Profiling inflammation and tissue injury markers in perfusate and bronchoalveolar lavage fluid during human ex vivo lung perfusion2017
Sarah Thompson
Beatriz Martinez Burgo
Professor John Kirby
Professor Neil Sheerin
Professor Simi Ali
et al.
Regulation of chemokine function: The roles of GAG-binding and post-translational nitration2017
Anders Andreasson
Dr Lee Borthwick
Dr Colin Gillespie
Kasim Jiwa
Jonathan Scott
et al.
The role of interleukin-1β as a predictive biomarker and potential therapeutic target during clinical ex vivo lung perfusion2017
Dr Tarana Singh Dang
Dr Joe Willet
Helen Griffin
Dr Graeme O'Boyle
Dr Mario Abinun
et al.
Defective Leukocyte Adhesion and Chemotaxis Contributes to Combined Immunodeficiency in Humans with Autosomal Recessive MST1 Deficiency2016
Professor Simi Ali
Differential CCR7 Targeting in Dendritic Cells by Three Naturally Occurring CC-Chemokines2016
Dr Tarana Singh Dang
Dr Joe Willet
Helen Griffin
Dr Graeme O'Boyle
Dr Mario Abinun
et al.
Erratum to: Defective Leukocyte Adhesion and Chemotaxis Contributes to Combined Immunodeficiency in Humans with Autosomal Recessive MST1 Deficiency (vol 36, pg 117, 2016)2016
Dr Bakiah Shaharuddin
Dr Charles Osei-Bempong
Professor Simi Ali
Dr Rachel Oldershaw
Dr Annette Meeson
et al.
Human limbal mesenchymal stem cells express ABCB5 and can grow on amniotic membrane2016
Beatriz Martinez Burgo
Professor Simi Ali
Jennifer Kirby
Professor Neil Sheerin
Ischemia-Reperfusion Injury Following Transplantation: Implications for the Modulation of CXCL8 Chemokine Function.2016
Shameem Sultanali Ladak
Professor Christopher Ward
Professor Simi Ali
MiRNA-200b Inhibits Epithelial-Mesenchymal Transition in TGF-b1 Induced Human Bronchial Epithelial Cells.2016
Shameem Ladak
Professor Christopher Ward
Professor Simi Ali
The potential role of microRNAs in lung allograft rejection2016
Professor John Kirby
Professor Simi Ali
The Role of Chemokine and Glycosaminoglycan Interaction in Chemokine-Mediated Migration In Vitro and In Vivo2016
Gabriel Cantanhede
Dr Vaughan Carter
Jennifer Kirby
Professor Simi Ali
The Role of HLA Class II Antibody in Endothelial Cell Activation and Allograft Rejection2016
Dr Anders Andreasson
Danai Karamanou
Dr Colin Gillespie
Dr Lee Borthwick
Kasim Jiwa
et al.
Treating Donor Lung Inflammation by Blocking Interleukin-1B-An In Vitro Therapy Testing Platform for Ex Vivo Lung Perfusion2016
Dr Gustavo Figueiredo
Dr Jeffry Hogg
Arthur Okonkwo
Dr Deborah Stocken
Professor Simi Ali
et al.
Understanding ocular surface inflammation in tears before and after ex vivo expanded autologous limbal stem cell transplantation2016
Professor Simi Ali
Glycosaminoglycan silencing by engineered CXCL12 variants2015
Laura Ferreras
Professor Neil Sheerin
Professor John Kirby
Professor Simi Ali
Mechanisms of renal graft chronic injury and progression to interstitial fibrosis2015
Shameem Sultanali Ladak
Professor Christopher Ward
Professor Simi Ali
MicroRNA-200b represses TGF-β1 induced EMT in BEAS-2B and primary bronchial epithelial cells2015
Dr Gustavo Figueiredo
Professor Simi Ali
Professor Francisco Figueiredo
Molecular analysis of inflammation in pannus tissue from patients with total limbal stem cell deficiency by quantitative real time PCR2015
Stephen Douglass
Dr Annette Meeson
Dr Dorota Overbeck-Zubrzycka
Dr John Brain
Dr Chris Lamb
et al.
Breast cancer metastasis: demonstration that FOXP3 regulates CXCR4 expression and the response to CXCL122014
Dr Bakiah Shaharuddin
Ian Harvey
Dr Sajjad Ahmad
Professor Simi Ali
Dr Annette Meeson
et al.
Characterisation of Human Limbal Side Population Cells Isolated Using an Optimised Protocol From an Immortalised Epithelial Cell Line and Primary Limbal Cultures2014
Professor Simi Ali
From di-peptides to whole proteins: exploiting peptide chemistry in the total synthesis of CCl2 and the rational design of new chemokine inhibitors2014
Dr Bakiah Shaharuddin
Professor Simi Ali
Dr Annette Meeson
Limbal side population cells; a future treatment for limbal stem cell deficiency2014
Sarah Thompson
Dr Rachael Redgrave
Professor John Kirby
Professor Helen Arthur
Professor Simi Ali
et al.
Modulation of wound healing post-myocardial infarction2014
Julia Spielhofer
Professor John Kirby
Professor Simi Ali
Role of 6-O-Sulfated Heparan Sulfate in Chronic Renal Fibrosis2014
Shameem Sultanali Ladak
Professor Simi Ali
Professor Christopher Ward
The potential role of miRNA-200b in the development of Bronchiolitis obliterans syndrome2014
Catriona Barker
Professor Simi Ali
Dr Graeme O'Boyle
Professor John Kirby
Transplantation and inflammation: implications for the modification of chemokine function2014
Fatmah Naemi
Professor John Kirby
Professor Simi Ali
Anti-Donor HLA Class I Antibodies: Pathways to Endothelial Cell Activation and Cell-Mediated Allograft Rejection2013
Professor Simi Ali
Professor Neil Sheerin
Biomarkers of acute injury: predicting the long-term outcome after transplantation2013
Dr Graeme O'Boyle
Professor Simi Ali
Professor John Kirby
Comment on "CXCL19 causes heterologous desensitization of CXCL12-mediated memory T cell activation"2013
Stephen Douglass
Professor Simi Ali
Dr Annette Meeson
Professor John Kirby
Erratum to: The role of FOXP3 in the development and metastatic spread of breast cancer (vol 31, pg 843, 2012)2013
Professor John Kirby
Professor Simi Ali
Evaluation of two cyclic di-peptides as inhibitors of CCL2 induced chemotaxis2013
Professor John Kirby
Professor Simi Ali
From Di-peptides to Whole Proteins: Exploiting Peptide Chemistry in the Rational Design of New Chemokine Inhibitors2013
Professor Christopher Ward
Professor Simi Ali
Identification of biomolecular marker of chronic lung allograft rejection2013
Dr Bakiah Shaharuddin
Dr Sajjad Ahmad
Dr Annette Meeson
Professor Simi Ali
Immunological Properties of Ocular Surface and Importance of Limbal Stem Cells for Transplantation2013
Dr Joe Willet
Dr Watchara Pichitsiri
Dr Sarah Jenkinson
Dr John Brain
Dr Katrina Wood
et al.
Kidney transplantation: analysis of the expression and T cell-mediated activation of latent TGF-β2013
Arthur Okonkwo
Shameem Sultanali Ladak
Professor Simi Ali
Professor John Kirby
Kidney transplantation: chronic molecular signatures in acute kidney injury2013
Dr Bakiah Shaharuddin
Dr Sajjad Ahmad
Professor Simi Ali
Dr Annette Meeson
Limbal Side Population cells: a future treatment for limbal stem cell deficiency2013
Marcin Pekalski
Dr Sarah Jenkinson
Dr Joe Willet
Dr Elizabeth Poyner
Dr Helen Robertson
et al.
Renal allograft rejection: Examination of delayed differentiation of Treg and Th17 effector T cells2013
Eirini Giannoudaki
Professor John Kirby
Professor Simi Ali
Sphingosine 1-phosphate in ischemia-reperfusion injury: effects on trans-endothelial migration of neutrophils2013
Professor John Kirby
Professor Simi Ali
Antibody-Mediated Allograft Inflammation: A Study of Endothelial Cell Activation2012
Dr Graeme O'Boyle
Christopher Fox
Dr Hannah Walden
Dr Joe Willet
Dr Emily Mavin
et al.
Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation2012
Fatmah Naemi
Professor Simi Ali
Professor John Kirby
HLA class I antibodies activate endothelial cells and UP-regulate adhesion molecules; a potential link between antibodies and cellular rejection2012
Dr David Swan
Professor John Kirby
Professor Simi Ali
Post-Transplant Immunosuppression: Regulation of the Efflux of Allospecific Effector T Cells from Lymphoid Tissues2012
Dr Emily Mavin
Dr Shaheda Ahmed
Dr Graeme O'Boyle
Brie Turner
Stephen Douglass
et al.
Regulatory T Cells Inhibit CD8+ T-Cell Tissue Invasion in Human Skin Graft-Versus-Host Reactions2012
Professor Simi Ali
Professor John Dark
Professor John Kirby
Strategies for inhibition of chemokine (CCL2) mediated monocyte migration in lethal reperfusion injury2012
Professor Simi Ali
Dr Annette Meeson
Professor John Kirby
The role of FOXP3 in the development and metastatic spread of breast cancer2012
Fatmah Naemi
Professor Simi Ali
Professor John Kirby
Antibody-mediated allograft rejection: The emerging role of endothelial cell signalling and transcription factors2011
Xiaomeng Wang
Brie Turner
Dr Graeme O'Boyle
Dr Saeed Ahmed
Dr Emily Mavin
et al.
Blocking effector T-cell trafficking contributes to regulatory T-cell mediated suppression of GvHD reactions2011
Dr Graeme O'Boyle
Professor Simi Ali
Professor John Kirby
Chemokines in transplantation: what can atypical receptors teach us about anti-inflammatory therapy?2011
Dr Dorota Overbeck-Zubrzycka
Professor Simi Ali
Professor John Kirby
Professor Thomas Lennard
FOXP3 transcription factor regulates metastatic spread of breast cancer via control of expression of CXCR4 chemokine receptor2011
Dr Graeme O'Boyle
Professor Simi Ali
Professor John Kirby
A strategy to inhibit effector T cell infiltration of allograft tissues by stimulation of the chemokine receptor CXCR32010
Dr Helen Marshall
Dr Helen Robertson
Professor John Kirby
Professor Simi Ali
Dr Graeme O'Boyle
et al.
Cardiac Allograft Rejection: Examination of the Expression and Function of the Decoy Chemokine Receptor D62010
Professor John Dark
Professor John Kirby
Professor Simi Ali
Investigating the role of chemokine-mediated activation of VLA-4 and its function in leukocyte migration2010
Dr David Swan
Professor John Kirby
Professor Simi Ali
Modulation of T lymphocyte responses to chemokines by sphingosine 1-phosphate2010
Dr Watchara Pichitsiri
Dr Joe Willet
Dr Sarah Jenkinson
Professor Simi Ali
Professor John Kirby
et al.
Renal allograft failure: can intragraft T cells activate latent TGF-beta?2010
Julia Spielhofer
Professor Simi Ali
Professor John Kirby
Role of heparan sulphate 6-O sulphation in modulating FGF-2 signalling during chronic rejection2010
Jonna Nilsson
Professor Simi Ali
Ian Harvey
Professor John Kirby
Dr Annette Meeson
et al.
Stem cell therapy: a role for CXCR4 in homing bone marrow side population cells to areas of myocardial damage2010
Fatmah Naemi
Professor John Kirby
Professor Simi Ali
The role of anti-HLA class I antibodies in graft outcome: rejection versus accommodation2010
Professor Simi Ali
Dr Graeme O'Boyle
Philippa Hepplewhite
Dr Helen Robertson
Professor John Kirby
et al.
Therapy with Nonglycosaminoglycan-Binding Mutant CCL7: A Novel Strategy to Limit Allograft Inflammation2010
Dr David Swan
Professor John Kirby
Professor Simi Ali
Vascular biology: the role of sphingosine 1-phosphate in both the resting state and inflammation2010
Dr Graeme O'Boyle
Paul Mellor
Professor John Kirby
Professor Simi Ali
Anti-inflammatory therapy by intravenous delivery of non-heparan sulfate-binding CXCL122009
Professor Simi Ali
Professor John Kirby
Professor Thomas Lennard
Expression of FOXP3 in human breast cancer is inversely correlated with disease progression and the metastatic process: an immunohistochemical study2009
Dr Graeme O'Boyle
Professor Simi Ali
Professor John Kirby
T cell extravasation: Demonstration of synergy between activation of CXCR3 and the T cell receptor2009
abdul Al-Hamidi
Marcin Pekalski
Dr Helen Robertson
Professor Simi Ali
Professor John Kirby
et al.
Chemokines have a potential role to modulate the adhesive function of CD103+T cells in renal allograft rejection2008
Dr David Swan
Dr Graeme O'Boyle
Professor John Kirby
Professor Simi Ali
Differential effects of S1P on responses to homeostatic versus inflammatory chemokines2008
Professor Simi Ali
Maureen Kirkley
Professor John Kirby
Leukocyte extravasation: An immunoregulatory role for α-L-Fucosidase?2008
Professor Simi Ali
Professor John Kirby
Professor Thomas Lennard
Mouse mammary tumor virus: a cause of breast cancer in humans?2008
abdul Al-Hamidi
Marcin Pekalski
Dr Helen Robertson
Professor Simi Ali
Professor John Kirby
et al.
Renal allograft rejection: The contribution of chemokines to the adhesion and retention of αE(CD103)β7 integrin-expressing intratubular T cells2008
Professor Simi Ali
Dr Graeme O'Boyle
Paul Mellor
Professor John Kirby
An apparent paradox: Chemokine receptor agonists can be used for anti-inflammatory therapy2007
Dr Graeme O'Boyle
Dr John Brain
Professor John Kirby
Professor Simi Ali
Chemokine-mediated inflammation: Identification of a possible regulatory role for CCR22007
Professor Simi Ali
Chemokines: Novel targets for breast cancer metastasis2007
james Harvey
Paul Mellor
Professor Thomas Lennard
Professor John Kirby
Professor Simi Ali
et al.
Inhibition of CXCR4-mediated breast cancer metastasis: A potential role for heparinoids?2007
Paul Mellor
james Harvey
Dr Debbie Pye
Dr Graeme O'Boyle
Professor Thomas Lennard
et al.
Modulatory effects of heparin and short-length oligosaccharides of heparin on the metastasis and growth of LMD MDA-MB 231 breast cancer cells in vivo2007
Professor John Kirby
Professor Simi Ali
Professor Thomas Lennard
Role of the chemokine receptor CXCR4 in breast cancer metastasis2007
Professor Simi Ali
Dr Helen Robertson
Professor John Isaacs
Professor John Kirby
A non-glycosaminoglycan-binding variant of CC chemokine ligand 7 (monocyte chemoattractant protein-3) antagonizes chemokine-mediated inflammation2005
Dr Graeme O'Boyle
Professor John Kirby
Professor Simi Ali
Differential chemokine signalling through CCR22005
james Harvey
Professor Simi Ali
Professor John Kirby
Professor Thomas Lennard
Immunological prevention of breast cancer metastasis using heparins2005
james Harvey
Paul Mellor
Professor Simi Ali
Professor John Kirby
Professor Thomas Lennard
et al.
Low molecular weight heparins as inhibitors of carcinoma metastasis2005
james Harvey
Professor Simi Ali
Professor John Kirby
Professor Thomas Lennard
Low molecular weight heparins as inhibitors of carcinoma metastasis2005
Professor Fiona Oakley
Professor Jelena Mann
Professor Simi Ali
Professor Derek Mann
Nuclear Factor-κB1 (p50) Limits the Inflammatory and Fibrogenic Responses to Chronic Injury2005
Professor Simi Ali
Dr Ghada Malik
Adam Burns
Dr Helen Robertson
Professor John Kirby
et al.
Renal transplantation: Examination of the regulation of chemokine binding during acute rejection2005
Dr Helen Robertson
Professor Simi Ali
Professor Alastair Burt
Professor John Kirby
Chronic Renal Allograft Dysfunction: The Role of T Cell-Mediated Tubular Epithelial to Mesenchymal Cell Transition2004
Dr Lynne Hardy
Dr Trevor Booth
Professor Simi Ali
Professor John Kirby
Examination of MCP-1 (CCL2) partitioning and presentation during transendothelial leukocyte migration2004
Professor Simi Ali
Professor John Kirby
Endothelial inflammation: the role of differential expression of N-deacetylase/N-sulphotransferase enzymes in alteration of the immunological properties of heparan sulphate2003
Professor Simi Ali
Professor John Kirby
Endothelial inflammation: The role of differential expression of N-deacetylease/N-sulphotransferase enzymes in alteration of the immunological properties of heparan sulphate2003
Professor Simi Ali
Professor John Kirby
Emeritus Professor Paul Flecknell
Professor John Dark
Improvements in lung compliance after pulmonary transplantation: Correlation with interleukin 8 expression2003
Professor Simi Ali
Louise Hardy
Professor John Kirby
Transplant immunobiology: A crucial role for heparan sulfate glycosaminoglycans?2003
Dr Helen Robertson
Helen Carroll
Professor Simi Ali
Professor John Kirby
Tubulitis in renal allograft rejection: role of TGFb and IL-15 in development and maintenance of CD103+T cells2003
Dr Helen Robertson
Helen Carroll
Professor Simi Ali
Professor John Kirby
Tubulitis in renal allograft rejection: Role of transforming growth factor-β and interleukin-15 in development and maintenance of CD103+ intraepithelial T cells2003
Professor Simi Ali
Sarah Fritchley
Dr Benjamin Chaffey
Professor John Kirby
Contribution of the putative heparan sulfate-binding motif BBXB of RANTES to transendothelial migration2002
Julie Wain
Professor John Kirby
Professor Simi Ali
Leucocyte chemotaxis: Examination of mitogen-activated protein kinase and phosphoinositide 3-kinase activation by Monocyte Chemoattractant Proteins-1, -2, -3 and -42002
Professor Simi Ali
Professor John Kirby
Accelerating the induction of Fas-mediated T cell apoptosis: A strategy for transplant tolerance?2001
Professor Simi Ali
Dr Adrian Palmer
Sarah Fritchley
Yvonne Maley
Professor John Kirby
et al.
Multimerization of monocyte chemoattractant protein-1 is not required for glycosaminoglycan-dependent transendothelial chemotaxis2001
Michelle Dowsland
Professor Simi Ali
Professor John Kirby
Professor Thomas Lennard
TNF-alpha affects CXCR4 gene expression and apoptosis in the breast cancer cell line MCF-7.2001
Professor Simi Ali
Dr Adrian Palmer
Sarah Fritchley
Professor John Kirby
Examination of the function of RANTES, MIP-1α, and MIP-1β following interaction with heparin-like glycosaminoglycans2000
Sarah Fritchley
Professor John Kirby
Professor Simi Ali
The antagonism of interferon-gamma (IFN-γ) by heparin: Examination of the blockade of class II MHC antigen and heat shock protein-70 expression2000
Professor Derek Manas
Professor Simi Ali
Professor John Kirby
David Talbot
The impact of cytomegalovirus serology for 7-year graft survival in cadaveric kidney transplantation - The Newcastle experience2000
Professor Simi Ali
Emeritus Professor Harry Gilbert
Emeritus Professor Barry Hirst
Dr Judith Hall
Bacterial xylanase expression in mammalian cells and transgenic mice1999
Professor Simi Ali
Emmett O'Flaherty
Thomas Griffiths
Professor David Neal
Professor John Kirby
et al.
Bladder cancer immunogenicity: expression of CD80 and CD86 is insufficient to allow primary CD4(+) T cell activation in vitro1999
Professor Simi Ali
Thomas Griffiths
Professor David Neal
Professor John Kirby
Bladder cancer immunogenicity: expression of CD80 and CD86 is insufficient to allow primary CD4+T cell activation in vitro1999