Publications by Emeritus Professor John Kirby - ePrints

Browsing publications by Emeritus Professor John Kirby.

Newcastle Authors	Title	Year
Lucy Gee Dr Ben Barron-Millar Dr Marco Zaki Dr Saimir Luli Rachel Burgoyne et al.	Anti–Cholestatic Therapy with Obeticholic Acid Improves Short-Term Memory in Bile Duct–Ligated Mice	2023
Irene del Molino del Barrio Dr Georgie Wilkins Dr Annette Meeson Professor Simi Ali Emeritus Professor John Kirby et al.	Correction to: Breast Cancer: An Examination of the Potential of ACKR3 to Modify the Response of CXCR4 to CXCL12 (International Journal of Molecular Sciences, (2018), 19, 11, (3592), 10.3390/ijms19113592)	2023
Dr Georgie Wilkins Dr Jenny Gilmour Eirini Giannoudaki Emeritus Professor John Kirby Professor Neil Sheerin et al.	Dissecting the Therapeutic Mechanisms of Sphingosine-1-Phosphate Receptor Agonism during Ischaemia and Reperfusion	2023
Dr Paraskevi Mallini Dr Kamilla Mahkamova Professor Thomas Lennard Emeritus Professor John Kirby Dr Gendie Lash et al.	Hypoxia-Driven TGFβ Modulation of Side Population Cells in Breast Cancer: The Potential Role of ERα	2023
Sarah Thompson Chong Pang Dr Tom Hellyer Dr Jonathan Scott Professor John Simpson et al.	Nitration of Chemokine CXCL8 acts as a natural mechanism to limit acute inflammation	2023
Shannon Jamieson Amy Mawdesley Dr Philip Hyde Emeritus Professor John Kirby Professor Alison Tyson-Capper et al.	Activation of Osteoblasts by Cobalt-Chromium Occurs Via a TLR4-Mediated Pathway	2022
Dr Janet Berrington Emeritus Professor John Kirby Lauren Beck Dr Chris Lamb Dr Christopher Stewart et al.	Mechanisms affecting the gut of preterm infants in enteral feeding trials: a nested cohort within a randomised controlled trial of lactoferrin	2022
Irene del Molino del Barrio Dr Annette Meeson Katie Cooke Dr Imad Malki Dr Ben Barron-Millar et al.	Contribution of heparan sulphate binding in CCL21-mediated migration of breast cancer cells	2021
Vic Hart Marco Silipo Swapna Satam Dr Hannah Gautrey Emeritus Professor John Kirby et al.	HER2-PI9 and HER2-I12: two novel and functionally active splice variants of the oncogene HER2 in breast cancer	2021
Shannon Jamieson Amy Mawdesley Professor David Deehan Emeritus Professor John Kirby Professor Alison Tyson-Capper et al.	Inflammatory responses to metal oxide ceramic nanopowders	2021
Nina Jordan Dr Sam Tingle Victoria Shuttleworth Katie Cooke Dr Rachael Redgrave et al.	MiR-126-3p Is Dynamically Regulated in Endothelial-to-Mesenchymal Transition during Fibrosis	2021
Dr Meghan Acres Dr Gill Hulme Dr Christopher Carey Dr John Mansfield Emeritus Professor John Kirby et al.	Regulation and role of αE integrin and gut homing integrins in migration and retention of intestinal lymphocytes during inflammatory bowel disease	2021
Dr Nicola Wyatt Dr Ally Speight Dr Christopher Stewart Emeritus Professor John Kirby Dr Chris Lamb et al.	Targeting leukocyte trafficking in inflammatory bowel disease	2021
Dr Ben Barron-Millar Dr Laura Ogle Emeritus Professor John Kirby Dr Jeremy Palmer Dr Laura Jopson et al.	The Serum Proteome and Ursodeoxycholic Acid Response in Primary Biliary Cholangitis	2021
Emerita Professor Alison Tyson-Capper Dr Philip Hyde Emeritus Professor John Kirby	Understanding the immunobiology of orthopaedic biomaterials	2021
Shannon Jamieson Professor Alison Tyson-Capper Dr Philip Hyde Emeritus Professor John Kirby	Understanding the immunobiology of orthopaedic biomaterials	2021
Amy Mawdesley Dr Sami Anjum Emeritus Professor John Kirby Professor Alison Tyson-Capper	Effect of cobalt ions on chemokine expression: Case report of immune cell infiltration in patient undergoing replacement of a metal-on-metal implant	2020
Beatriz Martinez Burgo Emeritus Professor John Kirby Professor Neil Sheerin Professor Simi Ali	A C-terminal CXCL8 peptide based on chemokine-glycosaminoglycan interactions reduces neutrophil adhesion and migration during inflammation	2019
Dr Chris Lamb Dr John Mansfield Emeritus Professor John Kirby	The Importance of Molecular Immune Investigation in Therapeutic Clinical Development for Biomarker Assessment	2019
Dr Chris Lamb Anna Long Dr John Mansfield Emeritus Professor John Kirby	AlphaE Integrin Expression Is Increased in the Ileum Relative to the Colon and Unaffected by Inflammation	2018
Irene del Molino del Barrio Dr Georgie Wilkins Dr Annette Meeson Professor Simi Ali Emeritus Professor John Kirby et al.	Breast Cancer: An Examination of the Potential of ACKR3 to Modify the Response of CXCR4 to CXCL12	2018
Dr Chris Lamb Emeritus Professor John Kirby	Donor intravascular monocyte trafficking: A potential therapeutic target for primary graft dysfunction following lung transplantation?	2018
Emeritus Professor John Kirby Dr Deborah Stocken Professor Heather Cordell	Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score	2018
Dr Chris Lamb Dr John Mansfield Anna Long Maria Price Dr Graeme O'Boyle et al.	aEß7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis	2017
Catriona Barker Sarah Thompson Dr Graeme O'Boyle Professor Neil Sheerin Professor Simi Ali et al.	CCL2 nitration is a negative regulator of chemokine-mediated inflammation	2017
Professor Nicholas Embleton Dr Janet Berrington Emeritus Professor John Kirby Dr Chris Lamb Professor Stephen Rushton et al.	Mechanisms Affecting the Gut of Preterm Infants in Enteral Feeding Trials	2017
Sarah Thompson Beatriz Martinez Burgo Emeritus Professor John Kirby Professor Neil Sheerin Professor Simi Ali et al.	Regulation of chemokine function: The roles of GAG-binding and post-translational nitration	2017
Dr Amy Anderson Dr David Swan Oliver Eltherington Dr Arthur Pratt Dr Gary Reynolds et al.	Tolerogenic dendritic cells generated with dexamethasone and vitamin D3 regulate rheumatoid arthritis CD4⁺ T-cells partly via TGF-β1	2017
Dr Chris Lamb Dr John Mansfield Emeritus Professor John Kirby	Association Between Response to Etrolizumab and Expression of Integrin alpha E and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis	2016
Dr Helen Lawrence Professor David Deehan James Holland Dr Sami Anjum Amy Mawdesley et al.	Cobalt ions recruit inflammatory cells in vitro through human Toll-like receptor 4	2016
Dr Sami Anjum Dr Helen Lawrence James Holland Emeritus Professor John Kirby Professor David Deehan et al.	Effect of cobalt-mediated Toll-like receptor 4 activation on inflammatory responses in endothelial cells	2016
Dr Helen Lawrence Amy Mawdesley James Holland Emeritus Professor John Kirby Professor David Deehan et al.	Targeting Toll-like receptor 4 prevents cobalt-mediated inflammation	2016
Emeritus Professor John Kirby Professor Simi Ali	The Role of Chemokine and Glycosaminoglycan Interaction in Chemokine-Mediated Migration In Vitro and In Vivo	2016
Dr Richard Speight Tracey Davey Dr Kathryn White Emeritus Professor John Kirby Dr John Mansfield et al.	Activation of the bile acid receptor, farnesoid-x receptor, maintains gut epithelial cell morphology, possibly via inhibition of myosin light chain kinase expression	2015
Dr Richard Speight Anna Whitehead Dr Gillian Patman Dr John Mansfield Professor Helen Reeves et al.	Activation of the bile acid receptor, Farnesoid-X Receptor, may reduce Ileal Inflammatory Cytokine expression in an animal model of diet-induced obesity	2015
Laura Ferreras Professor Neil Sheerin Emeritus Professor John Kirby Professor Simi Ali	Mechanisms of renal graft chronic injury and progression to interstitial fibrosis	2015
Dr Michael Keir Dr John Mansfield Dr Chris Lamb Emeritus Professor John Kirby	AlphaE integrin expression as a predictive biomarker for induction of clinical remission by etrolizumab: Analysis of a phase II trial in moderate-to-severely active ulcerative colitis	2014
Stephen Douglass Dr Annette Meeson Dr Dorota Overbeck-Zubrzycka Dr John Brain Dr Chris Lamb et al.	Breast cancer metastasis: demonstration that FOXP3 regulates CXCR4 expression and the response to CXCL12	2014
Dr Helen Lawrence Professor David Deehan James Holland Emeritus Professor John Kirby Professor Alison Tyson-Capper et al.	Can cobalt from metal-on-metal joints activate human TLR4 and cause an inflammatory response?	2014
Paraskevi Mallini Professor Thomas Lennard Emeritus Professor John Kirby Dr Annette Meeson	Epithelial-to-mesenchymal transition: What is the impact on breast cancer stem cells and drug resistance	2014
Dr John Mansfield Dr Chris Lamb Emeritus Professor John Kirby	Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial	2014
Sarah Thompson Dr Rachael Redgrave Emeritus Professor John Kirby Professor Helen Arthur Professor Simi Ali et al.	Modulation of wound healing post-myocardial infarction	2014
Julia Spielhofer Emeritus Professor John Kirby Professor Simi Ali	Role of 6-O-Sulfated Heparan Sulfate in Chronic Renal Fibrosis	2014
Dr Helen Lawrence Professor David Deehan Emeritus Professor John Kirby Professor Alison Tyson-Capper	The immunobiology of cobalt: demonstration of a potential aetiology for inflammatory pseudotumours after metal-on-metal replacement of the hip	2014
Catriona Barker Professor Simi Ali Dr Graeme O'Boyle Emeritus Professor John Kirby	Transplantation and inflammation: implications for the modification of chemokine function	2014
Dr Jeremy Palmer Professor David Jones Dr Jess Dyson Emeritus Professor John Kirby	Understanding the Mechanisms Underpinning Treatment Non-Response in Primary Biliary Cirrhosis: A Tool for Treatment Stratification	2014
Dr Jeremy Palmer Dr Jess Dyson Professor David Jones Emeritus Professor John Kirby	Understanding the mechanisms underpinning treatment non-response in Primary Biliary Cirrhosis: a tool for treatment stratification	2014
Fatmah Naemi Emeritus Professor John Kirby Professor Simi Ali	Anti-Donor HLA Class I Antibodies: Pathways to Endothelial Cell Activation and Cell-Mediated Allograft Rejection	2013
Dr John Brain Dr Helen Robertson Dr Aaron Ions Gardner Dr Trevor Booth Professor Thomas von Zglinicki et al.	Biliary Epithelial Senescence and Plasticity in Acute Cellular Rejection	2013
Dr Graeme O'Boyle Professor Simi Ali Emeritus Professor John Kirby	Comment on "CXCL19 causes heterologous desensitization of CXCL12-mediated memory T cell activation"	2013
Professor Alastair Burt Catriona Barker Emeritus Professor John Kirby Dr John Brain	Development of a robust protocol for gene expression analysis using formalin-fixed, paraffin-embedded liver transplant biopsy specimens	2013
Stephen Douglass Professor Simi Ali Dr Annette Meeson Emeritus Professor John Kirby	Erratum to: The role of FOXP₃ in the development and metastatic spread of breast cancer (vol 31, pg 843, 2012)	2013
Emeritus Professor John Kirby Professor Simi Ali	Evaluation of two cyclic di-peptides as inhibitors of CCL2 induced chemotaxis	2013
Emeritus Professor John Kirby Professor Simi Ali	From Di-peptides to Whole Proteins: Exploiting Peptide Chemistry in the Rational Design of New Chemokine Inhibitors	2013
Dr Joe Willet Dr Watchara Pichitsiri Dr Sarah Jenkinson Dr John Brain Dr Katrina Wood et al.	Kidney transplantation: analysis of the expression and T cell-mediated activation of latent TGF-β	2013
Arthur Okonkwo Shameem Sultanali Ladak Professor Simi Ali Emeritus Professor John Kirby	Kidney transplantation: chronic molecular signatures in acute kidney injury	2013
Professor Alison Tyson-Capper Dr Helen Lawrence James Holland Professor David Deehan Emeritus Professor John Kirby et al.	Metal-on-metal hips: cobalt can induce an endotoxin-like response	2013
Marcin Pekalski Dr Sarah Jenkinson Dr Joe Willet Dr Elizabeth Poyner Dr Helen Robertson et al.	Renal allograft rejection: Examination of delayed differentiation of Treg and Th17 effector T cells	2013
Eirini Giannoudaki Emeritus Professor John Kirby Professor Simi Ali	Sphingosine 1-phosphate in ischemia-reperfusion injury: effects on trans-endothelial migration of neutrophils	2013
Professor Alison Tyson-Capper Dr Helen Lawrence James Holland Professor David Deehan Emeritus Professor John Kirby et al.	The Molecular Mechanism of Cell Activation by Cobalt Ions. Comment on Ninomiya et al.: Metal Ions Activate Vascular Endothelial Cells and Increase Lymphocyte Chemotaxis and Binding	2013
Dr John Brain Emma Thompson Professor Alastair Burt Emeritus Professor John Kirby	Allografts, Immunosupression and Autophagy: A Conspiracy to Fibrose?	2012
Emeritus Professor John Kirby Professor Simi Ali	Antibody-Mediated Allograft Inflammation: A Study of Endothelial Cell Activation	2012
Dr Chris Lamb Dr Graeme O'Boyle Professor David Jones Dr John Mansfield Emeritus Professor John Kirby et al.	Blockade of the B7 integrin prevents adherence of t lymphocytes to MAdCAM-1 in an in vitro model of vascular microcirculation post-capillary shear flow	2012
Dr Graeme O'Boyle Christopher Fox Dr Hannah Walden Dr Joe Willet Dr Emily Mavin et al.	Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation	2012
Marta Gorowiec Dr Lee Borthwick Dr Sean Parker Emeritus Professor John Kirby Dr Gabriele Saretzki et al.	Free radical generation induces epithelial-to-mesenchymal transition in lung epithelium via a TGF-beta 1-dependent mechanism	2012
Fatmah Naemi Professor Simi Ali Emeritus Professor John Kirby	HLA class I antibodies activate endothelial cells and UP-regulate adhesion molecules; a potential link between antibodies and cellular rejection	2012
Dr David Swan Emeritus Professor John Kirby Professor Simi Ali	Post-Transplant Immunosuppression: Regulation of the Efflux of Allospecific Effector T Cells from Lymphoid Tissues	2012
Dr Amena Shelleh Emeritus Professor John Kirby Professor Steve Robson Professor Alison Tyson-Capper	Preterm Birth: A Modulatory Role for HMGB1?	2012
Javed Sultan Professor Michael Griffin Emeritus Professor John Kirby Dr Brian Shenton Emeritus Professor Chris Seal et al.	Randomized clinical trial of omega-3 fatty acid-supplemented enteral nutrition versus standard enteral nutrition in patients undergoing oesophagogastric cancer surgery	2012
Professor Simi Ali Professor John Dark Emeritus Professor John Kirby	Strategies for inhibition of chemokine (CCL2) mediated monocyte migration in lethal reperfusion injury	2012
Professor Simi Ali Dr Annette Meeson Emeritus Professor John Kirby	The role of FOXP3 in the development and metastatic spread of breast cancer	2012
Fatmah Naemi Professor Simi Ali Emeritus Professor John Kirby	Antibody-mediated allograft rejection: The emerging role of endothelial cell signalling and transcription factors	2011
Dr Marzena Ciechomska Professor Thomas Lennard Emeritus Professor John Kirby Dr Andrew Knight	B lymphocytes acquire and present intracellular antigens that have relocated to the surface of apoptotic target cells	2011
Dr Kelly Britton Emeritus Professor John Kirby Professor Thomas Lennard Dr Annette Meeson	Cancer Stem Cells and Side Population Cells in Breast Cancer and Metastasis	2011
Dr Graeme O'Boyle Professor Simi Ali Emeritus Professor John Kirby	Chemokines in transplantation: what can atypical receptors teach us about anti-inflammatory therapy?	2011
Dr Dorota Overbeck-Zubrzycka Professor Simi Ali Emeritus Professor John Kirby Professor Thomas Lennard	FOXP3 transcription factor regulates metastatic spread of breast cancer via control of expression of CXCR4 chemokine receptor	2011
Dr Ellen Hatch Professor Louise Parker Emeritus Professor John Kirby Professor Neil Sheerin	Infiltrating renal T cells are activated and respond to self antigen	2011
Dr John Brain Professor Alastair Burt Emeritus Professor John Kirby Dr Helen Robertson	Investigation of the Fate of Cholangiocytes in Cholestatic Liver Disease	2011
Emeritus Professor John Kirby Dr Graeme O'Boyle	Lung Transplantation: The Yin and Yang of Mesenchymal Stem Cells	2011
Dr Hannah Walden Dr Abigail Vallance Danai Karamanou Christopher Fox Dr Anthony Rostron et al.	The Alarmin HMGB1 Is an Inflammatory Mediator in Brain Death Induced Lung Damage	2011
Dr Graeme O'Boyle Professor Simi Ali Emeritus Professor John Kirby	A strategy to inhibit effector T cell infiltration of allograft tissues by stimulation of the chemokine receptor CXCR3	2010
Dr Helen Marshall Dr Helen Robertson Emeritus Professor John Kirby Professor Simi Ali Dr Graeme O'Boyle et al.	Cardiac Allograft Rejection: Examination of the Expression and Function of the Decoy Chemokine Receptor D6	2010
Emeritus Professor John Kirby Liz Shiells Professor Steve Robson Professor Alison Tyson-Capper	Characterisation of HMGB1 in the Human Myometrium during Pregnancy	2010
Dr Anthony Rostron Dr David Cork Vassillios Avlonitis Professor Andrew Fisher Professor John Dark et al.	Contribution of Toll-Like Receptor Activation to Lung Damage After Donor Brain Death	2010
Dr Hannah Walden Danai Karamanou Christopher Fox Dr Anthony Rostron Emeritus Professor John Kirby et al.	Evaluation of secretory leucoprotease inhibitor (SLPI) as an anti-inflammatroy therapy for donor lung inflammation	2010
Dr Lee Borthwick Marta Gorowiec Dr Malcolm Brodlie Professor Christopher Ward Dr James Lordan et al.	Inflammation and Epithelial to Mesenchymal Transition in Lung Transplant Recipients: Role in Dysregulated Epithelial Wound Repair	2010
Dr Abigail Vallance Dr Hannah Walden Danai Karamanou Christopher Fox Dr Anthony Rostron et al.	Investigating HMGB1 as a potential inflammatory mediator in brain death induced lung damage	2010
Professor John Dark Emeritus Professor John Kirby Professor Simi Ali	Investigating the role of chemokine-mediated activation of VLA-4 and its function in leukocyte migration	2010
Dr David Swan Emeritus Professor John Kirby Professor Simi Ali	Modulation of T lymphocyte responses to chemokines by sphingosine 1-phosphate	2010
Dr Watchara Pichitsiri Dr Joe Willet Dr Sarah Jenkinson Professor Simi Ali Emeritus Professor John Kirby et al.	Renal allograft failure: can intragraft T cells activate latent TGF-beta?	2010
Julia Spielhofer Professor Simi Ali Emeritus Professor John Kirby	Role of heparan sulphate 6-O sulphation in modulating FGF-2 signalling during chronic rejection	2010
Jonna Nilsson Professor Simi Ali Ian Harvey Emeritus Professor John Kirby Dr Annette Meeson et al.	Stem cell therapy: a role for CXCR4 in homing bone marrow side population cells to areas of myocardial damage	2010
Dr Karolina Rygiel Dr Helen Robertson Dr Joe Willet Dr John Brain Professor Alastair Burt et al.	T Cell-Mediated Biliary Epithelial-to-Mesenchymal Transition in Liver Allograft Rejection	2010
Fatmah Naemi Emeritus Professor John Kirby Professor Simi Ali	The role of anti-HLA class I antibodies in graft outcome: rejection versus accommodation	2010
Professor Simi Ali Dr Graeme O'Boyle Philippa Hepplewhite Dr Helen Robertson Emeritus Professor John Kirby et al.	Therapy with Nonglycosaminoglycan-Binding Mutant CCL7: A Novel Strategy to Limit Allograft Inflammation	2010
Vassillios Avlonitis Christopher Wigfield Emeritus Professor John Kirby Professor John Dark	Treatment of the brain-dead lung donor with aprotinin and nitric oxide	2010
Dr David Swan Emeritus Professor John Kirby Professor Simi Ali	Vascular biology: the role of sphingosine 1-phosphate in both the resting state and inflammation	2010
Dr Jeremy Palmer Dr Hannah Walden Emeritus Professor John Kirby Professor David Jones	680: Incorporation of 6-bromohexanoic acid (6BH) into cellular pyruvate dehydrogenase complex (PDC): Further evidence for generation of an autoimmunogenic neoantigen in primary billary cirrhosis (PBC)	2009
Dr Graeme O'Boyle Paul Mellor Emeritus Professor John Kirby Professor Simi Ali	Anti-inflammatory therapy by intravenous delivery of non-heparan sulfate-binding CXCL12	2009
Dr Lee Borthwick Dr Sean Parker Kate Brougham Marta Gorowiec Professor Christopher Ward et al.	Epithelial to mesenchymal transition (EMT) and airway remodelling after human lung transplantation	2009
Professor Simi Ali Emeritus Professor John Kirby Professor Thomas Lennard	Expression of FOXP3 in human breast cancer is inversely correlated with disease progression and the metastatic process: an immunohistochemical study	2009
Dr Anthony Rostron Dr David Cork Emeritus Professor John Kirby Professor John Dark	Norepinephrine and Arginine Vasopressin Increase Hepatic but Not Renal Inflammatory Activation During Hemodynamic Resuscitation in a Rodent Model of Brain-dead Donors	2009
Dr Lee Borthwick Dr Malcolm Brodlie Professor Christopher Ward Dr James Lordan Emeritus Professor John Kirby et al.	Pro-inflammatory Cytokines IL-1 beta and TNT alpha, but Not IL-8, Cause Aberrant Lung Epithelial Wound Repair Via TGF-beta 1 Driven Epithelial to Mesenchymal Transition (EMT)	2009
Richard Charnley Dr Avinash Sewpaul Jeremy French Dr Tien Kheng Khoo Emeritus Professor John Kirby et al.	Soluble E-cadherin: An early marker of severity in acute pancreatitis	2009
Dr Graeme O'Boyle Professor Simi Ali Emeritus Professor John Kirby	T cell extravasation: Demonstration of synergy between activation of CXCR3 and the T cell receptor	2009
Dr John Brain Dr Anthony Rostron Professor John Dark Emeritus Professor John Kirby	Activation and modulation of cardiac poly-adenosine diphosphate ribose polymerase activity in a rat model of brain death	2008
Dr Helen Marshall Dr Helen Robertson Professor Alastair Burt Professor David Jones Emeritus Professor John Kirby et al.	Biliary epithelial to mesenchymal transition contributes to portal tract fibrogenesis in primary sclerosing cholangitis	2008
Vassillios Avlonitis Chris Wigfield Dr Huw Golledge Dr Anthony Rostron Emeritus Professor John Kirby et al.	Brain stem auditory evoked response for confirmation of brain death in the rat	2008
Simon Dovedi Emeritus Professor John Kirby Dr Barry Davies Professor Hing Leung John Kelly et al.	Celecoxib has Potent Antitumour Effects as a Single Agent and in Combination with BCG Immunotherapy in a Model of Urothelial Cell Carcinoma	2008
abdul Al-Hamidi Marcin Pekalski Dr Helen Robertson Professor Simi Ali Emeritus Professor John Kirby et al.	Chemokines have a potential role to modulate the adhesive function of CD103+T cells in renal allograft rejection	2008
Marcin Pekalski Dr Helen Robertson Dr Karolina Rygiel abdul Al-Hamidi Dr Sarah Jenkinson et al.	Chronic renal allograft rejection: does T cell-mediated immunoregulation of pro-inflammatory Th17 cells contribute to tubulointerstitial fibrosis?	2008
Dr David Swan Dr Graeme O'Boyle Emeritus Professor John Kirby Professor Simi Ali	Differential effects of S1P on responses to homeostatic versus inflammatory chemokines	2008
Emeritus Professor John Kirby Dr Helen Robertson Dr Helen Marshall Dr Karolina Rygiel Dr Mark Hudson et al.	Epithelial to mesenchymal transition in primary sclerosing cholangitis	2008
Emeritus Professor John Kirby Dr Helen Robertson Helen Marshall Dr Karolina Rygiel Dr Mark Hudson et al.	Epithelial to mesenchymal transition in primary sclerosing cholangitis	2008
Dr Karolina Rygiel Dr Helen Robertson Dr Helen Marshall Marcin Pekalski Liena Zhao et al.	Epithelial-mesenchymal transition contributes to portal tract fibrogenesis during human chronic liver disease	2008
Dr Anthony Rostron Vassillios Avlonitis Dr David Cork Danielle Grenade Emeritus Professor John Kirby et al.	Hemodynamic Resuscitation With Arginine Vasopressin Reduces Lung Injury After Brain Death in the Transplant Donor	2008
Dr Jeremy Palmer Professor David Jones Emeritus Professor John Kirby	Human Th17 cells: investigation of T cell differentiation in the presence of TGF-beta and a range of pro-inflammatory cytokines	2008
Professor Simi Ali Maureen Kirkley Emeritus Professor John Kirby	Leukocyte extravasation: An immunoregulatory role for α-L-Fucosidase?	2008
Professor Simi Ali Emeritus Professor John Kirby Professor Thomas Lennard	Mouse mammary tumor virus: a cause of breast cancer in humans?	2008
Marta Gorowiec Dr Lee Borthwick Marcin Pekalski Dr James Lordan Emeritus Professor Nick Europe-Finner et al.	Oxidative stress induces epithelial to mesenchymal transition in human lung epithelial cells through transforming groeth factor beta and integrin beta6-dependent mechanism	2008
Dr Lee Borthwick Kate Brougham Professor Christopher Ward Dr James Lordan Emeritus Professor John Kirby et al.	Pro-inflammatory cytokines dysregulate lung epithelial wound repair via epithelial to mesenchymal transition	2008
abdul Al-Hamidi Marcin Pekalski Dr Helen Robertson Professor Simi Ali Emeritus Professor John Kirby et al.	Renal allograft rejection: The contribution of chemokines to the adhesion and retention of αE(CD103)β7 integrin-expressing intratubular T cells	2008
Dr Anthony Rostron Vassillios Avlonitis Dr David Cork Professor John Dark Emeritus Professor John Kirby et al.	The contribution of toll-like receptors (TLR) to brain death-induced donor lung inflammation	2008
Dr Marzena Ciechomska Professor Thomas Lennard Emeritus Professor John Kirby Dr Andrew Knight	The role of B cells in the induction of anti-tumour immunity	2008
Professor David Jones Dr Jeremy Palmer Professor Alastair Burt Emeritus Professor John Kirby	The specificity of liver inflammation in mouse models of primary biliary cirrhosis	2008
Dr Lee Borthwick Dr Sean Parker Marta Gorowiec Professor Christopher Ward Dr James Lordan et al.	Tumour necrosis factor-α accentuates transforming growth factor-β driven epithelial to mesenchymal transition (EMT) in airway epithelial cells from lung transplant recipients	2008
Dr Hannah Walden Emeritus Professor John Kirby Emeritus Professor Steve Yeaman Dr Joseph Gray Professor David Jones et al.	Xenobiotic Incorporation into Pyruvate Dehydrogenase Complex Can Occur Via the Exogenous Lipoylation Pathway	2008
Professor Simi Ali Dr Graeme O'Boyle Paul Mellor Emeritus Professor John Kirby	An apparent paradox: Chemokine receptor agonists can be used for anti-inflammatory therapy	2007
Dr Helen Robertson Emeritus Professor John Kirby Professor David Jones Professor Alastair Burt	Biliary epithelial-mesenchymal transition in posttransplantation recurrence of primary biliary cirrhosis	2007
Dr Graeme O'Boyle Dr John Brain Emeritus Professor John Kirby Professor Simi Ali	Chemokine-mediated inflammation: Identification of a possible regulatory role for CCR2	2007
Vassillios Avlonitis Chris Wigfield Dr Huw Golledge Emeritus Professor John Kirby Professor John Dark et al.	Early hemodynamic injury during donor brain death determines the severity of primary graft dysfunction after lung transplantation	2007
Dr Anthony Rostron Vassillios Avlonitis Emeritus Professor John Kirby Professor John Dark	Hemodynamic resuscitation of the brain-dead organ donor and the potential role of vasopressin	2007
Christopher Huggins Emeritus Professor John Kirby Professor James Shaw	In vitro and in vivo evaluation of intrinsic immunogenicity of reporter and insulin gene therapy plasmids	2007
james Harvey Paul Mellor Professor Thomas Lennard Emeritus Professor John Kirby Professor Simi Ali et al.	Inhibition of CXCR4-mediated breast cancer metastasis: A potential role for heparinoids?	2007
Paul Mellor james Harvey Dr Debbie Pye Dr Graeme O'Boyle Professor Thomas Lennard et al.	Modulatory effects of heparin and short-length oligosaccharides of heparin on the metastasis and growth of LMD MDA-MB 231 breast cancer cells in vivo	2007
Marta Gorowiec Dr Sean Parker Dr Lee Borthwick Professor Christopher Ward Dr James Lordan et al.	Oxidative stress increases transforming growth factor-beta expression and drives epithelial to mesenchymal transition in human lung epithelial cells	2007
Dr Anthony Rostron Vassillios Avlonitis David Cork Danielle Grenade Emeritus Professor John Kirby et al.	Resuscitation of the brain dead organ donor with arginine vasopressin (AVP) - An alternative vasoconstrictor	2007
Emeritus Professor John Kirby Professor Simi Ali Professor Thomas Lennard	Role of the chemokine receptor CXCR4 in breast cancer metastasis	2007
Emeritus Professor John Kirby	Role of the mucosal integrin αE(CD103)β7 in tissue-restricted cytotoxicity	2007
Dr Hannah Walden Dr Jeremy Palmer Emeritus Professor John Kirby Dr Stuart Kendrick Professor David Jones et al.	Substrate promiscuity in the pyruvate dehydrogenase complex (PDC) lipoylation pathway: Xenobiotic incorporation as a potential mechanism for the pathogenesis of primary biliary cirrhosis (PBC)	2007
Professor David Jones Dr Amanda Robe Dr Jeremy Palmer Emeritus Professor John Kirby	Adoptive transfer of self-PDC reactive T-cells into naive mice induces portal tract and bile duct changes characteristic of primary biliary cirrhosis (PBC)	2006
Jennifer Tyler Dr Helen Robertson Dr Trevor Booth Professor Alastair Burt Emeritus Professor John Kirby et al.	Chronic allograft nephropathy: Intraepithelial signals generated by transforming growth factor-β and bone morphogenetic protein-7	2006
Emeritus Professor John Kirby Professor Patrick Chinnery	Clinical features of hereditary spastic paraplegia due to spastin mutation	2006
Dr Karolina Rygiel Dr Helen Robertson Professor Alastair Burt Professor David Jones Emeritus Professor John Kirby et al.	Demonstration of the transition of intrahepatic biliary epithelial cells to fibroblasts during chronic inflammatory liver diseases	2006
Vassillios Avlonitis Emeritus Professor John Kirby Professor John Dark	Donor treatment with nitric oxide does not improve reperfusion injury after transplantation of lungs damaged by brain death.	2006
Vassillios Avlonitis Dr Anthony Rostron Emeritus Professor John Kirby Professor John Dark	The donor lung improves with time and aprotinin treatment after brain death	2006
Julie Birraux Emeritus Professor John Kirby Professor Mark Thomason Dr John Taylor	The effect of cyclosporin on cell division and apoptosis in human oral keratinocytes	2006
Dr Anna Broad Professor David Jones Emeritus Professor John Kirby	Toll-like receptor (TLR) response tolerance: A key physiological "damage limitation" Effect and an important potential opportunity for therapy	2006
Dr Anna Broad Emeritus Professor John Kirby Professor David Jones	Toll-like receptor interactions: Tolerance of MyD88-dependent cytokines but enhancement of MyD88-independent interferon-β production	2006
Emeritus Professor John Kirby John Kelly	[abstract] Polarisation of a T-helper cell immune response by CpG-oligonucleotides: a potential immunotherapy for bladder cancer	2005
Dr Arun Natarajan Emeritus Professor John Kirby	A guide to oral presentaiton skills	2005
Dr Amanda Robe Emeritus Professor John Kirby Professor David Jones Dr Jeremy Palmer	A key role for autoreactive B cells in the breakdown of T-cell tolerance to pyruvate dehydrogenase complex in the mouse	2005
Dr Amanda Robe Emeritus Professor John Kirby Professor David Jones Dr Jeremy Palmer	A key role for autoreactive B cells in the breakdown of T-cell tolerance to pyruvate dehydrogenase complex in the mouse	2005
Professor Simi Ali Dr Helen Robertson Professor John Isaacs Emeritus Professor John Kirby	A non-glycosaminoglycan-binding variant of CC chemokine ligand 7 (monocyte chemoattractant protein-3) antagonizes chemokine-mediated inflammation	2005
Emeritus Professor Nick Europe-Finner Emeritus Professor John Kirby	A role for cytokine measurement in therapeutic monitoring of immunosuppressive drugs following lung transplantation	2005
Emeritus Professor Nick Europe-Finner Emeritus Professor John Kirby	A role for cytokine measurement in therapeutic monitoring of immunosuppressive drugs following lung transplantation	2005
Vassillios Avlonitis Emeritus Professor John Kirby Professor John Dark	Brain-death-related mechanisms of reperfusion injury after lung transplantation	2005
Dr Helen Robertson Emeritus Professor John Kirby Jennifer Tyler	Chronic renal graft dysfunction: A role for CD103+T cells in epithelial to mesenchymal transition?	2005
Simon Dovedi Emeritus Professor John Kirby Dr Helen Maitland Dr Barry Davies John Kelly et al.	Cyclooxygenase-2 inhibition: A potential mechanism for increasing the efficacy of bacillus Calmette-Guerin immunotherapy for bladder cancer	2005
Dr Graeme O'Boyle Emeritus Professor John Kirby Professor Simi Ali	Differential chemokine signalling through CCR2	2005
Vassillios Avlonitis Emeritus Professor John Kirby Professor John Dark	Early hemodynamic lung injury during donor brain death enhances reperfusion injury after lung transplantation	2005
Dr Helen Robertson Xin Xu Professor Alastair Burt Emeritus Professor John Kirby	Epithelial to mesenchymal transition in chronic cholestatic liver disease	2005
Dr Ian Forrest Dr James Lordan Dr Gary Pritchard Professor David Jones Dr Helen Robertson et al.	Epithelial to mesenchymal transition in clinically stable lung transplant recipients	2005
Liena Zhao Dr Helen Robertson Emeritus Professor John Kirby Professor David Jones Professor Alastair Burt et al.	Epithelial-mesenchymal transition in portal fibrosis	2005
Ajay Gupta Dr Brian Shenton Susan Stamp Bryon Jaques Professor Derek Manas et al.	Functional assessment of Epstein Barr virus specific cytotoxic T cells using MHC class I-PEPTIDE complexes	2005
Professor Christopher Ward Dr Helen Robertson Dr Ian Forrest Dr James Lordan Denis Murphy et al.	Hypothesis: Epithelial-to-mesenchymal transition is a common cause of chronic allograft failure	2005
james Harvey Professor Simi Ali Emeritus Professor John Kirby Professor Thomas Lennard	Immunological prevention of breast cancer metastasis using heparins	2005
Marcin Pekalski Dr Helen Robertson John Taylor Emeritus Professor John Kirby	Kidney transplantation: an association between FOXP3 and chronic graft failure?	2005
abdul Al-Hamidi Jennifer Tyler Dr Helen Robertson Emeritus Professor John Kirby	Kidney transplantation: does CCR9 play a role in rejection?	2005
james Harvey Paul Mellor Professor Simi Ali Emeritus Professor John Kirby Professor Thomas Lennard et al.	Low molecular weight heparins as inhibitors of carcinoma metastasis	2005
james Harvey Professor Simi Ali Emeritus Professor John Kirby Professor Thomas Lennard	Low molecular weight heparins as inhibitors of carcinoma metastasis	2005
Professor Christopher Ward Dr Ian Forrest Dr Helen Robertson Emeritus Professor Tim Cawston Professor Andrew Fisher et al.	Phenotype of airway epithelial cells suggests epithelial to mesenchymal cell transition in clinically stable lung transplant recipients	2005
Professor Simi Ali Dr Ghada Malik Adam Burns Dr Helen Robertson Emeritus Professor John Kirby et al.	Renal transplantation: Examination of the regulation of chemokine binding during acute rejection	2005
Emeritus Professor John Kirby Louise Ward Professor Pamela Shaw	Screening of the regulatory and coding regions of vascular endothelial growth factor in amyotrophic lateral sclerosis	2005
Vassillios Avlonitis Emeritus Professor John Kirby Professor John Dark	The effect of time from donor brain death to retrieval on reperfusion injury after lung transplantation	2005
Vassillios Avlonitis Chris Wigfield Emeritus Professor John Kirby Professor John Dark	The hemodynamic mechanisms of lung injury and systemic inflammatory response following brain death in the transplant donor	2005
Dr Jeremy Palmer Emeritus Professor John Kirby Professor David Jones	Apoptosis as a mechanism for cell surface expression of the autoantigen pyruvate dehydrogenase complex	2004
Dr Amanda Robe Dr Jeremy Palmer Emeritus Professor John Kirby Professor David Jones	Breakdown of T-cell tolerance to the primary biliary cirrhosis (PBC) autoantigen pyruvate dehydrogenase complex is a B-cell driven process	2004
Dr Amanda Robe Dr Jeremy Palmer Emeritus Professor John Kirby Professor David Jones	Breakdown of T-cell tolerance to the primary biliary cirrhosis (PBC) autoantigen pyruvate dehydrogenase complex is a B-cell driven process	2004
Dr Helen Robertson Professor Simi Ali Professor Alastair Burt Emeritus Professor John Kirby	Chronic Renal Allograft Dysfunction: The Role of T Cell-Mediated Tubular Epithelial to Mesenchymal Cell Transition	2004
Dr Jeremy Palmer Dr Amanda Robe Professor Alastair Burt Emeritus Professor John Kirby Professor David Jones et al.	Covalent modification as a mechanism for the breakdown of immune tolerance to pyruvate dehydrogenase complex in the mouse	2004
Vassillios Avlonitis Chris Wigfield Emeritus Professor John Kirby Professor John Dark	Elimination of the hemodynamic sequelae of brain death prevents systemic inflammatory response syndrome (SIRS) and acute lung injury (ALI) in the transplant donor	2004
Dr Ian Forrest Dr James Lordan Dr Helen Robertson Emeritus Professor Tim Cawston Professor John Dark et al.	Epithelial to mesenchymal transition in clinically stable lung transplantation	2004
Jarupa Ratanamart Dr Kathleen Scougall Emeritus Professor John Kirby Professor James Shaw	Establishment of an in vitro bioassay for immunogenicity of bacterial lipopolysaccharide and unmethylated CpG motifs in plasmid-derived gene therapy vectors	2004
Dr Lynne Hardy Dr Trevor Booth Professor Simi Ali Emeritus Professor John Kirby	Examination of MCP-1 (CCL2) partitioning and presentation during transendothelial leukocyte migration	2004
Dr Ahmed Chishti Dr Brian Shenton Emeritus Professor John Kirby Dr Simon Baudouin	Neutrophil chemotaxis and receptor expression in clinical septic shock	2004
Professor Janice Ellis Emeritus Professor John Kirby Dr John Taylor Professor Mark Thomason	Plasma TGF-β1 as a risk factor for gingival overgrowth	2004
Emeritus Professor John Kirby Dr Helen Robertson	Tubular epithelial cell to fibroblast transition in chronic renal allograft dysfunction.	2004
Professor David Jones Emeritus Professor John Kirby	Cell-surface expression of PDC during apoptosis: A possible route for autoantigen presentation in PBC?	2003
Julie Birraux Professor Mark Thomason Emeritus Professor John Kirby Dr John Taylor	Effects of cyclosporin A on gingival epithelial cells	2003
Professor Simi Ali Emeritus Professor John Kirby	Endothelial inflammation: the role of differential expression of N-deacetylase/N-sulphotransferase enzymes in alteration of the immunological properties of heparan sulphate	2003
Professor Simi Ali Emeritus Professor John Kirby	Endothelial inflammation: The role of differential expression of N-deacetylease/N-sulphotransferase enzymes in alteration of the immunological properties of heparan sulphate	2003
Professor Simi Ali Emeritus Professor John Kirby Emeritus Professor Paul Flecknell Professor John Dark	Improvements in lung compliance after pulmonary transplantation: Correlation with interleukin 8 expression	2003
Dr Doug Aitchison Hannah Orr Emeritus Professor Paul Flecknell Emeritus Professor John Kirby Professor John Dark et al.	Nitric oxide during perfusion improves posttransplantation function of non-heart-beating donor lungs	2003
Dr Helen Maitland Dr Barry Davies Emeritus Professor John Kirby John Kelly	Polarisation of a T helper cell immune response by CpG-containing oligonucleotides: A potential immunotherapy for bladder cancer	2003
Helen Atkins Dr Barry Davies Emeritus Professor John Kirby John Kelly	Polarisation of a T-helper cell immune response by activation of dendritic cells with CpG-containing oligonucleotides: A potential therapeutic regime for bladder cancer immunotherapy	2003
Dr Helen Robertson Emeritus Professor John Kirby	Post-transplant renal tubulitis: The recruitment, differentiation and persistence of intra-epithelial T cells	2003
Vassillios Avlonitis Professor Andrew Fisher Emeritus Professor John Kirby Professor John Dark	Pulmonary transplantation: The role of brain death in donor lung injury	2003
Emeritus Professor John Kirby Michael Bone Dr Helen Robertson Dr Mark Hudson Professor David Jones et al.	The number of intraepithelial T cells decreases from ascending colon to rectum [1]	2003
Professor Simi Ali Louise Hardy Emeritus Professor John Kirby	Transplant immunobiology: A crucial role for heparan sulfate glycosaminoglycans?	2003
Dr Helen Robertson Helen Carroll Professor Simi Ali Emeritus Professor John Kirby	Tubulitis in renal allograft rejection: role of TGFb and IL-15 in development and maintenance of CD103+T cells	2003
Dr Helen Robertson Helen Carroll Professor Simi Ali Emeritus Professor John Kirby	Tubulitis in renal allograft rejection: Role of transforming growth factor-β and interleukin-15 in development and maintenance of CD103+ intraepithelial T cells	2003
Dr Amanda Robe Dr Jeremy Palmer Emeritus Professor John Kirby Professor Margaret Bassendine Professor David Jones et al.	[abstract] Characterisation of liver infiltrating T-cell antigen specificity in a mouse model of primary biliary cirrhosis (PBC)	2002
Joanne Cresswell Matthew Henry Dr Helen Robertson Professor David Neal Emeritus Professor John Kirby et al.	Adhesion of lymphocytes to bladder cancer cells: The role of the αEβ7 integrin	2002
Chris Wigfield Dr Huw Golledge Dr Brian Shenton Emeritus Professor John Kirby Professor John Dark et al.	Ameliorated reperfusion injury in lung transplantation after reduction of brain death induced inflammatory graft damage in the donor	2002
Professor David Jones Dr Jeremy Palmer Professor Alastair Burt Dr Amanda Robe Emeritus Professor John Kirby et al.	Bacterial motif DNA as an adjuvant for the breakdown of immune self-tolerance to pyruvate dehydrogenase complex	2002
Dr Jeremy Palmer Emeritus Professor John Kirby Professor David Jones	Breakdown of tolerance is seen to both PDC-E2 and PDC-E3BP, individual antigens in primary biliary cirrhosis, in a mouse model of PDC autoreactivity	2002
Dr Pamela MacDonald Emeritus Professor John Kirby Professor David Jones	Cell-surface expression of pyruvate dehydrogenase complex during apoptosis: A possible route for autoantigen presentation in primary biliary cirrhosis	2002
Dr Amanda Robe Dr Jeremy Palmer Emeritus Professor John Kirby Professor David Jones	Characterisation of liver infiltrating T-cell antigen specificity in a mouse model of primary biliary cirrhosis (PBC)	2002
Sarah Fritchley Dr Benjamin Chaffey Emeritus Professor John Kirby	Contribution of the putative heparan sulfate-binding moif BBXB of RANTES to transendothelial migrationwth factor beta(a) expression and rejection grade	2002
Professor Simi Ali Sarah Fritchley Dr Benjamin Chaffey Emeritus Professor John Kirby	Contribution of the putative heparan sulfate-binding motif BBXB of RANTES to transendothelial migration	2002
Emeritus Professor John Kirby Fiona Menzies Dr Mark Cookson Emerita Professor Katherine Bushby Professor Pamela Shaw et al.	Differential gene expression in a cell culture model of SOD1-related familial motor neurone disease	2002
Professor David Neal Emeritus Professor John Kirby	Evaluation of dendritic cell immunogenicity after activation and chemical fixation: A mixed lymphocyte reaction model	2002
Michelle Dowsland Emeritus Professor John Kirby Professor Thomas Lennard	Heparin blocks stromal derived factor-1 induced migration via CXCR4 in breast cancer cells	2002
Julie Wain Emeritus Professor John Kirby Professor Simi Ali	Leucocyte chemotaxis: Examination of mitogen-activated protein kinase and phosphoinositide 3-kinase activation by Monocyte Chemoattractant Proteins-1, -2, -3 and -4	2002
Professor David Jones Dr Jeremy Palmer Dr Amanda Robe Emeritus Professor John Kirby	Oral tolerisation to pyruvate dehydrogenase complex as a potential therapy for primary biliary cirrhosis	2002
Jeremy French Joanne Cresswell Wai Wong Richard Charnley Emeritus Professor John Kirby et al.	T cell adhesion and cytolysis of pancreatic cancer cells: A role for E-cadherin in immunotherapy?	2002
Jeremy French Joanne Cresswell Richard Charnley Emeritus Professor John Kirby	T-cell adhesion and cytolysis of pancreatic cancer cells: a role for E-cadherin in immunotherapy	2002
Dr Jeremy Palmer Emeritus Professor John Kirby Professor David Jones	The immunology of primary biliary cirrhosis: The end of the beginning?	2002
Professor Simi Ali Emeritus Professor John Kirby	Accelerating the induction of Fas-mediated T cell apoptosis: A strategy for transplant tolerance?	2001
Joanne Cresswell Dr Helen Robertson Professor David Neal Thomas Griffiths Emeritus Professor John Kirby et al.	Distribution of lymphocytes of the αEβ7 phenotype and E-cadherin in normal human urothelium and bladder carcinomas	2001
Dr Ahmed Chishti Professor John Dark Dr Patrick Kesteven Dr Hazel Powell Dr Christopher Snowden et al.	Expression of chemokine receptors CXCR1 and CXCR2 during cardiopulmonary bypass	2001
Dr Doug Aitchison Hannah Orr Emeritus Professor Paul Flecknell Emeritus Professor John Kirby Professor John Dark et al.	Functional assessment of non-heart-beating donor lungs: Prediction of post-transplant function	2001
Dr Nicholas Hoenich Dr Christopher Snowden Professor Derek Manas Emeritus Professor John Kirby David Talbot et al.	Machine perfusion for kidneys: How to do it at minimal cost	2001
Professor Simi Ali Dr Adrian Palmer Sarah Fritchley Yvonne Maley Emeritus Professor John Kirby et al.	Multimerization of monocyte chemoattractant protein-1 is not required for glycosaminoglycan-dependent transendothelial chemotaxis	2001
Dr Ahmed Chishti Emeritus Professor John Kirby Dr Simon Baudouin	Neutrophil CXC chemokine receptor expression in sepsis	2001
Dr Helen Robertson Professor Alastair Burt David Talbot Emeritus Professor John Kirby	Relationship between TGF beta(1), intratubular CD103 positive T cells and acute renal allograft rejection	2001
Dr Helen Robertson Emeritus Professor John Kirby	Renal allograft rejection: The development and function of tubulitis	2001
Professor Alastair Burt Dr Helen Robertson Emeritus Professor John Kirby David Talbot	TGF-β expression in protocol transplant liver biopsies: A comparative study between cyclosporine-A (CyA) and tacrolimus (FK 506) immunosuppression	2001
Professor Alastair Burt Dr Helen Robertson Emeritus Professor John Kirby David Talbot	TGF-β expression in protocol transplant liver biopsies: a comparative study between cyclosporine-A (CyA) and tacrolimus (FK 506) immunosuppression	2001
Michelle Dowsland Professor Simi Ali Emeritus Professor John Kirby Professor Thomas Lennard	TNF-alpha affects CXCR4 gene expression and apoptosis in the breast cancer cell line MCF-7.	2001
Dr Helen Robertson Emeritus Professor John Kirby David Talbot	Transforming growth factor-beta 1 plasma levels in stable renal allograft recipients under different immunosuppression - Response	2001
Dr Helen Robertson David Talbot Professor Alastair Burt Emeritus Professor John Kirby	Tubulitis after renal transplantation: Demonstration of an association between CD103+ T cells, transforming growth factor β1 expression and rejection grade	2001
Dr Helen Robertson Emeritus Professor John Kirby David Talbot	Active TGF-β1 expression in kidney transplantation: A comparative study of cyclosporin-A (CyA) and tacrolimus (FK506)	2000
Emeritus Professor John Kirby Professor Derek Manas David Talbot	Assessment of non-heart-beating donor (NHBD) kidneys for viability on machine perfusion	2000
Emeritus Professor Steve Yeaman Emeritus Professor John Kirby Professor David Jones	Autoreactive responses to pyruvate dehydrogenase complex in the pathogenesis of primary biliary cirrhosis	2000
David Talbot Dr Christopher Snowden Professor Derek Manas Emeritus Professor John Kirby	Comparison of proteolytic enzymes and glutathione S-transferase levels in non-heart-beating donors' (NHBD) kidney perfusates	2000
Professor Simi Ali Dr Adrian Palmer Sarah Fritchley Emeritus Professor John Kirby	Examination of the function of RANTES, MIP-1α, and MIP-1β following interaction with heparin-like glycosaminoglycans	2000
Emmett O'Flaherty Emeritus Professor John Kirby	Immune selection in neoplasia: towards a microevolutionary model of cancer development	2000
Emeritus Professor Nick Europe-Finner Dr Helen Robertson Professor Anthony De Soyza Emeritus Professor John Kirby	Intragraft Proliferating T Lymphocytes are associated with Moderate Acute Pulmonary Rejection 1	2000
Dr David Mantle Dr Brian Shenton Muhammed Gok Professor Naeem Soomro Professor Derek Manas et al.	Machine perfusion and viability assessment of non-heart-beating donor kidneys: A single-centre result	2000
Dr Christopher Snowden Professor Derek Manas Emeritus Professor John Kirby David Talbot	Non-heart-beating kidney donors (multiple letters)	2000
Emmett O'Flaherty Emeritus Professor John Kirby	Regulation of T-cell apoptosis: a mixed lymphocyte reaction model	2000
Dr Helen Robertson David Talbot Keith Callanan Emeritus Professor John Kirby	Renal allograft rejection: β-Chemokine involvement in the development of tubulitis	2000
Dr Jeremy Palmer Emeritus Professor John Kirby Emeritus Professor Steve Yeaman Professor Margaret Bassendine Professor David Jones et al.	Secretory autoantibodies in primary biliary cirrhosis (PBC)	2000
Emeritus Professor John Kirby	Selection of metastatic tumour phenotypes - Reply	2000
Dr Clare Morgan Dr Helen Robertson Professor Mark Thomason Emeritus Professor John Kirby Dr John Taylor et al.	TGF beta 1 in drug-induced gingival overgrowth: activation or synthesis?	2000
Dr Helen Robertson Emeritus Professor John Kirby David Talbot	TGF-β expression in renal transplant biopsies - A comparative study between cyclosporin-A and tacrolimus	2000
Sarah Fritchley Emeritus Professor John Kirby Professor Simi Ali	The antagonism of interferon-gamma (IFN-γ) by heparin: Examination of the blockade of class II MHC antigen and heat shock protein-70 expression	2000
Professor Derek Manas Professor Simi Ali Emeritus Professor John Kirby David Talbot	The impact of cytomegalovirus serology for 7-year graft survival in cadaveric kidney transplantation - The Newcastle experience	2000
Dr Christopher Snowden Dr Paul Griffiths Professor Derek Manas Emeritus Professor John Kirby	The trouble with kidneys derived from the non heart-beating donor: A single center 10-year experience	2000
Michael Bone Emeritus Professor John Kirby Dr Helen Robertson Professor Alastair Burt Dr Mark Hudson et al.	Ulcerative colitis: An investigation of the potential role played by a B-E(7) +VE T-cells	2000
Professor Simi Ali Emmett O'Flaherty Thomas Griffiths Professor David Neal Emeritus Professor John Kirby et al.	Bladder cancer immunogenicity: expression of CD80 and CD86 is insufficient to allow primary CD4(+) T cell activation in vitro	1999
Professor Simi Ali Thomas Griffiths Professor David Neal Emeritus Professor John Kirby	Bladder cancer immunogenicity: expression of CD80 and CD86 is insufficient to allow primary CD4+T cell activation in vitro	1999
Dr Jeremy Palmer Emeritus Professor John Kirby Emeritus Professor Steve Yeaman Professor David Jones	Persistence of secretory autoantibodies in PBC patients post-liver transplant: a potential mechanism for disease recurrence?	1999
Emmett O'Flaherty Richard Charnley Emeritus Professor John Kirby	Selection of metastatic tumour phenotypes by host immune systems	1999
Dr Clare Morgan Dr Helen Robertson Professor Mark Thomason Emeritus Professor John Kirby Dr John Taylor et al.	TGF-beta 1 associated with gingival overgrowth in transplant patients medicated with cyclosporin A	1999
Dr Helen Robertson Emeritus Professor John Kirby David Talbot	The effect of cyclosporin A and Tacrolimus on cultured human epithelial cells: The role of TGF-β	1999
Richard Bliss Emeritus Professor John Kirby Professor Thomas Lennard	Inhibition of endothelial adhesion and invasion by breast carcinoma cells may contribute towards the anti-metastatic effects of tamoxifen	1996
Richard Bliss Emeritus Professor John Kirby Professor Thomas Lennard	The role of beta-1 integrins in adhesion of 2 breast carcinoma cell lines to a model endothelium	1995
Richard Bliss Emeritus Professor John Kirby Professor Thomas Lennard	Effect of menstrual phase on surgical treatment of breast cancer	1994
Dr Ian Brotherick Dr Brian Shenton Emeritus Professor John Kirby Dr Jeremy Palmer Emeritus Professor Steve Yeaman et al.	Production of immunosuppressive factors by a cultured tumor cell line and their effect on lymphocyte proliferation and cells cycle response	1993
Emeritus Professor John Kirby Dr Brian Shenton Professor Thomas Lennard	Human endothelial cells: effect of TNF-alpha on peripheral blood mononuclear cell adhesion	1991
Emeritus Professor John Kirby Dr Brian Shenton Professor Thomas Lennard George Proud Robert Taylor et al.	Renal allograft rejection: functional impairment of kidney epithelial cell monolayers mediated by lymphokine activated killer cells and by antibody	1991
Emeritus Professor John Kirby George Proud Professor Thomas Lennard Robert Taylor	Renal allograft rejection: investigation of alloantigen presentation by cultured human renal epithelial cells	1991
Emeritus Professor John Kirby Dr Brian Shenton George Proud Professor Thomas Lennard Robert Taylor et al.	Renal epithelium: reversal of cytotoxic damage by addition of anti-thymocyte globulin	1991
Emeritus Professor John Kirby Dr Brian Shenton David Talbot Professor Thomas Lennard George Proud et al.	Renal allograft rejection: possible involvement of antibody dependent cell mediated cytotoxicity	1990