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Isoindolinone Inhibitors of the Murine Double Minute 2 (MDM2)-p53 Protein-Protein Interaction: Structure-Activity Studies Leading to Improved Potency

Lookup NU author(s): Dr Ian Hardcastle, Alex Liu, Dr Eric Valeur, Anna Watson, Dr Tim Blackburn, Dr Karim Bennaceur, Emeritus Professor Bill Clegg, Professor Jane Endicott, Professor Bernard Golding, Dr Karen Haggerty, Dr Ross Harrington, Dr Claire Hutton, Dr Xiaohong Lu, Emeritus Professor Herbie Newell, Professor Martin Noble, Charlotte Revill, Professor John Lunec


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Publication metadata

Author(s): Hardcastle IR, Liu J, Valeur E, Watson A, Ahmed SU, Blackburn TJ, Bennaceur K, Clegg W, Drummond C, Endicott JA, Golding BT, Griffin RJ, Gruber J, Haggerty K, Harrington RW, Hutton C, Kemp S, Lu X, McDonnell JM, Newell DR, Noble ME, Payne SL, Revill CH, Riedinger C, Xu Q, Lunec J

Publication type: Article

Publication status: Published

Journal: Journal of Medicinal Chemistry

Year: 2011

Volume: 54

Issue: 5

Pages: 1233-1243

Print publication date: 11/02/2011

ISSN (print): 0022-2623

ISSN (electronic): 1520-4804

Publisher: American Chemical Society


DOI: 10.1021/jm1011929

PubMed id: 21314128


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