Duncan Miller Tristan Reuillon Dr Lauren Molyneux Dr Tim Blackburn Dr Noel Edwards et al. | Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain Inhibitor | 2022 |
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Dr Ian Hardcastle Dr Ruth Bawn Dr Tim Blackburn Dr Celine Cano Dr Sarah Cully et al. | Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein–Protein Interaction | 2021 |
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Stephanie Myers Duncan Miller Dr Lauren Molyneux Dr Mercedeh Arasta Dr Ruth Bawn et al. | Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4 | 2019 |
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Dr Tim Blackburn
| Synthetic approaches to phomactins: Novel oxidation of homoallylic alcohols using tetra-n-propylammonium perruthenate | 2018 |
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Dr Tim Blackburn
| Synthetic approaches to phomactins: on the stereoselectivity of some [2,3]-Wittig rearrangements | 2015 |
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Dr Tim Blackburn Christopher Coxon Dr Xiaohong Lu Emeritus Professor Bernard Golding Professor Roger Griffin et al. | Diaryl- and triaryl-pyrrole derivatives: inhibitors of the MDM2-p53 and MDMX-p53 protein-protein interactions | 2013 |
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Dr Kelly Coffey Dr Tim Blackburn Susan Cook Emeritus Professor Bernard Golding Professor Roger Griffin et al. | Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer | 2012 |
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Dr Ian Hardcastle Alex Liu Dr Eric Valeur Anna Watson Shafiq Ahmed et al. | Isoindolinone Inhibitors of the Murine Double Minute 2 (MDM2)-p53 Protein-Protein Interaction: Structure-Activity Studies Leading to Improved Potency | 2011 |
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Dr Tim Blackburn
| Further studies of an approach to a total synthesis of phomactins | 2009 |
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Dr Tim Blackburn
| A Pyridazine Series of α2/α3 Subtype Selective GABAA Agonists for the Treatment of Anxiety | 2006 |
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