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Cyclin-Dependent Kinase (CDK) Inhibitors; Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines

Lookup NU author(s): Christopher Coxon, Dr Suzannah HarnorORCiD, Dr Mathew Martin, Dr Benoit Carbain, Emeritus Professor Bernard Golding, Dr Ian HardcastleORCiD, Lisa Harlow, Svitlana Korolchuk, Professor Herbie Newell, Professor Martin NobleORCiD, Dr Mangaleswaran Sivaprakasam, Dr Susan Tudhope, David Turner, Lan Wang, Professor Steve Wedge, Professor Jane Endicott, Dr Celine CanoORCiD



This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Publication metadata

Author(s): Coxon C, Anscombe E, Harnor S, Martin M, Carbain B, Golding B, Hardcastle I, Harlow L, Korolchuk S, Matheson C, Newell D, Noble M, Sivaprakasam M, Tudhope SJ, Turner D, Wang L, Wedge SR, Wong C, Griffin R, Endicott J, Cano C

Publication type: Article

Publication status: Published

Journal: Journal of Medicinal Chemistry

Year: 2017

Volume: 60

Pages: 1746-1767

Print publication date: 09/03/2017

Online publication date: 22/12/2016

Acceptance date: 23/08/2016

Date deposited: 15/02/2017

ISSN (print): 0022-2623

ISSN (electronic): 1520-4804

Publisher: American Chemical Society


DOI: 10.1021/acs.jmedchem.6b01254


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Funder referenceFunder name
C2115/A21421Cancer Research UK CRUK (closed comp)