Dr Evan Mulligan Dr Susan Tudhope Dr Jill Hunter Sarah Elliott Dr Jonathan Wallis et al. | Expression and Activity of the NF-κB Subunits in Chronic Lymphocytic Leukaemia: A Role for RelB and Non-Canonical Signalling | 2023 |
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Dr Catherine Salvini Benoit Darlot Jack Davison Dr Mathew Martin Dr Susan Tudhope et al. | Fragment expansion with NUDELs – poised DNA-encoded libraries | 2023 |
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Islam Al-Khawaldeh Dr Christine Basmadjian Dr Cinzia Bordoni Dr Suzannah Harnor Amy Heptinstall et al. | An alkynylpyrimidine-based covalent inhibitor that targets a unique cysteine in NF-κB-inducing kinase (NIK) | 2021 |
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Dr Timothy Barrow Dr Sirintra Nakjang Kateryna Bilotkach Dr Laura Woodhouse Gesa Junge et al. | Epigenome-wide analysis reveals functional modulators of drug sensitivity and post-treatment survival in chronic lymphocytic leukaemia | 2021 |
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Dr Catherine Willoughby Huw Thomas Dr Elaine Willmore Suzanne Kyle Dr Anita Wittner et al. | Selective DNA-PKcs Inhibition Extends the Therapeutic Index of Localized Radiotherapy and Chemotherapy | 2019 |
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Christopher Coxon Dr Suzannah Harnor Dr Mathew Martin Dr Benoit Carbain Emeritus Professor Bernard Golding et al. | Cyclin-Dependent Kinase (CDK) Inhibitors; Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines | 2017 |
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Dr Ziad Al-Oanzi Sofia Fountana Tabassum Moonira Dr Susan Tudhope John Petrie et al. | Opposite effects of a glucokinase activator and metformin on glucose-regulated gene expression in hepatocytes | 2017 |
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Dr Timothy Barrow Dr Laura Woodhouse Gesa Junge Dr Susan Tudhope Dr Jonathan Wallis et al. | The Role of HOXA4 in Chronic Lymphocytic Leukaemia Progression and Response to Therapy | 2016 |
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Dr Elaine Willmore Dr Aaron Ions Gardner Dr Susan Tudhope Belinda Murtani Jessica Caffry et al. | Novel small molecule IKK alpha inhibitors inhibit non- canonical NF-kappa B signaling and survival of primary CLL cells | 2015 |
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Dr Ashleigh Herriott Dr Susan Tudhope Gesa Junge Natalie Rodrigues Dr Miranda Patterson et al. | PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in Chronic Lymphocytic Leukaemia | 2015 |
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Dr Helen Marr Dr Luke Gaughan Dr Susan Tudhope Professor James Allan
| Regulation of CD38 in IRF4 in Chronic Lymphocytic Leukaemia | 2015 |
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Dr Susan Tudhope Dr Yan Zhao Dr Anita Wittner Annalisa Bertoli Santosh Adhikari et al. | Profiling inhibitors of MDM2: p53 and MDMX: p53 in relation to MDMX protein levels | 2014 |
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Dr Alessio Iannetti Dr Adeline Ledoux Dr Susan Tudhope Helene Sellier Adam Moore et al. | Regulation of p53 and Rb Links the Alternative NF-kappaB Pathway to EZH2 Expression and Cell Senescence | 2014 |
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Annalisa Bertoli Santosh Adhikari Dr Suzannah Harnor Dr Yan Zhao Professor John Lunec et al. | Validation studies with small-molecule modulators of the MDM2/MDMX-p53 binding interaction | 2014 |
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Dr John Petrie Dr Ziad Al-Oanzi Dr Catherine Arden Dr Susan Tudhope Professor Jelena Mann et al. | Glucose induces protein targeting to glycogen in hepatocytes by fructose 2,6-bisphosphate-mediated recruitment of MondoA to the promoter | 2013 |
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Dr Susan Tudhope Dr Fiona Malcomson Dr Catherine Arden Dr Laura Hampson Professor Loranne Agius et al. | A Novel Mechanism for Regulating Hepatic Glycogen Synthesis Involving Serotonin and Cyclin-Dependent Kinase-5 | 2012 |
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Dr Catherine Arden Dr Susan Tudhope Dr Ziad Al-Oanzi Kirsty Cullen Professor Loranne Agius et al. | Fructose 2,6-bisphosphate is essential for glucose-regulated genetranscription of glucose-6-phosphatase and other ChREBP target genes inhepatocytes | 2012 |
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Dr Susan Tudhope Dr Evan Mulligan Dr Jill Hunter Dr Helen Marr Professor barbara Durkacz et al. | P B S-1086, a "Pan-Rel" Inhibitor, Decreases Viability of Chronic Lymphocytic Leukemia Cells | 2012 |
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Dr Ziad Al-Oanzi Dr John Petrie Dr Susan Tudhope Dr Catherine Arden Professor Loranne Agius et al. | The insulin-independent glucose-induction of the hepatic gluconeogenic enzyme glucose 6-phosphatase involves distinct metabolic pathways and transcription factors | 2012 |
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Dr Catherine Arden Dr Susan Tudhope Dr Ziad Al-Oanzi Professor Loranne Agius
| Elevated glucose represses liver glucokinase and induces its regulatory protein to safeguard hepatic phosphate homeostasis | 2011 |
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Professor Fai Ng Dr Susan Tudhope Dr Alexei von Delwig Dr Desa Lilic
| Invariant natural killer T (iNKT) cell deficiency in chronic mucocutaneous candidiasis - A consequence or a cause? | 2011 |
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Dr Susan Tudhope Dr Alexei von Delwig Dr Jane Falconer Dr Arthur Pratt Professor John Isaacs et al. | Profound invariant natural killer T-cell deficiency in inflammatory arthritis | 2010 |
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Dr Alexei von Delwig Dr Arthur Pratt Dr Susan Tudhope Professor John Isaacs Professor Fai Ng et al. | Invariant natural killer T (iNKT) cells in early rheumatoid arthritis (RA) | 2008 |
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Dr Alexei von Delwig Dr Susan Tudhope Dr Arthur Pratt Professor John Isaacs Dr Desa Lilic et al. | The role of invariant natural killer T (iNKT) cells in rheumatoid arthritis | 2008 |
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