Dr Marzena Ciechomska Dr Steven O'Reilly Professor Fiona Oakley Professor Jaap van Laar
| Histone Demethylation and Toll-like Receptor 8-Dependent Cross-Talk in Monocytes Promotes Transdifferentiation of Fibroblasts in Systemic Sclerosis Via Fra-2 | 2016 |
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Dr Steven O'Reilly Dr Marzena Ciechomska Dr Nicola Fullard Professor Jaap van Laar
| IL-13 mediates collagen deposition via STAT6 and microRNA-135b: a role for epigenetics | 2016 |
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Dr Marzena Ciechomska Professor Jaap van Laar Dr Steven O'Reilly
| Current frontiers in systemic sclerosis pathogenesis | 2015 |
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Dr Marzena Ciechomska Dr Steven O'Reilly Professor Jaap van Laar
| A novel role of MIR-29a in inhibition of TAB1-mediated timp-1 production in dermal fibroblasts: implication for SSC pathogenesis | 2014 |
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Dr Marzena Ciechomska Dr Caroline Wilson Achilleas FLOUDAS Emeritus Professor Drew Rowan Professor John Robinson et al. | Antigen-specific B lymphocytes acquire proteoglycan aggrecan from cartilage extracellular matrix resulting in antigen presentation and CD4+ T-cell activation | 2014 |
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Dr Marzena Ciechomska Professor Jaap van Laar Dr Steven O'Reilly
| Emerging role of epigenetics in systemic sclerosis pathogenesis | 2014 |
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Dr Steven O'Reilly Dr Marzena Ciechomska Rachel Cant Professor Jaap van Laar
| Interleukin-6 (IL-6) Trans Signaling Drives a STAT3-dependent Pathway That Leads to Hyperactive Transforming Growth Factor-beta (TGF-beta) Signaling Promoting SMAD3 Activation and Fibrosis via Gremlin Protein | 2014 |
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Dr Marzena Ciechomska Dr Steven O'Reilly Monika Suwara Professor Jaap Van Laar
| MiR-29a Reduces TIMP-1 Production by Dermal Fibroblasts via Targeting TGF- β Activated Kinase 1 Binding Protein 1, Implications for Systemic Sclerosis | 2014 |
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Dr Steven O'Reilly Rachel Cant Dr Marzena Ciechomska Professor Fiona Oakley Professor Sophie Hambleton et al. | Serum Amyloid A (SAA) induces IL-6 in dermal fibroblasts via TLR2, IRAK4 and NF-κB | 2014 |
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Dr Steven O'Reilly Rachel Cant Dr Marzena Ciechomska James Finnigan Professor Fiona Oakley et al. | Serum amyloid A induces interleukin-6 in dermal fibroblasts via Toll-like receptor 2, interleukin-1 receptor-associated kinase 4 and nuclear factor-kappa B | 2014 |
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Dr Steven O'Reilly Rachel Cant Dr Marzena Ciechomska Professor Jaap van Laar
| Acute Serum Amyloid A (A-SSA) Induces TIMP-1 in Dermal Fibroblasts that is Mediated Via a TLR-Dependent and Formyl Receptor-Independent Pathway | 2013 |
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Dr Steven O'Reilly Rachel Cant Dr Marzena Ciechomska Professor Jaap Van Laar
| Interleukin-6: a new therapeutic target in systemic sclerosis? | 2013 |
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Dr Catherine Stroud Dr Mario Abinun Dr Steven O'Reilly Dr Marzena Ciechomska Dr Stephen Owens et al. | Late Onset Invasive Pneumococcal Disease in a Patient with IRAK4 Deficiency | 2013 |
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Dr Marzena Ciechomska Professor Jaap van Laar
| Role of FRA-2 in TLR8-Mediated TIMP-1 Production in Systemic Sclerosis | 2013 |
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Dr Marzena Ciechomska Rachel Cant James Finnigan Professor Jaap Van Laar Dr Steven O'Reilly et al. | Role of toll-like receptors in systemic sclerosis | 2013 |
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Dr Marzena Ciechomska Dr Bridget Griffiths Professor Sophie Hambleton Professor Jaap van Laar
| The Role of Serum Factors and Toll-Like Receptor Signaling in the Induction of Profibrotic TIMP-1 by Monocytes in Systemic Sclerosis | 2013 |
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Dr Marzena Ciechomska Christiaan Huigens Tess Stanly Dr Andreas Gessner Professor Sophie Hambleton et al. | Toll-like receptor-mediated, enhanced production of profibrotic TIMP-1 in monocytes from patients with systemic sclerosis: role of serum factors | 2013 |
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Dr Marzena Ciechomska Christiaan Huigens Dr Andreas Gessner Dr Steven O'Reilly Professor Jaap Van Laar et al. | A novel role of monocytes in the induction of profibrotic tissue-inhibitor of metalloproteinase-1 mediated by toll-like receptors stimulation in SSC | 2012 |
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Dr Steven O'Reilly Dr Marzena Ciechomska Professor Jaap Van Laar
| Interleukin-6, its role in fibrosing conditions | 2012 |
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Dr Marzena Ciechomska Dr Steven O'Reilly
| TOLL-LIKE RECEPTOR-MEDIATED EXPRESSION OF PROFIBROTIC MEDIATORS BY CIRCULATING MONOCYTES IN SYSTEMIC SCLEROSIS | 2012 |
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Dr Marzena Ciechomska Dr Andreas Gessner Dr Steven O'Reilly Professor Jaap Van Laar
| Toll-like receptor-mediated expression of profibrotic tissue-inhibitor of metalloproteinase-1 by circulating monocytes in Systemic sclerosis | 2012 |
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Dr Marzena Ciechomska Dr Caroline Wilson Emeritus Professor Drew Rowan Professor John Robinson Dr Andrew Knight et al. | Antigen-specific B cells can acquire and present the rheumatoid arthritis candidate autoantigen aggrecan from a non-internalisable surface | 2011 |
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Dr Marzena Ciechomska Professor Thomas Lennard Emeritus Professor John Kirby Dr Andrew Knight
| B lymphocytes acquire and present intracellular antigens that have relocated to the surface of apoptotic target cells | 2011 |
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Dr Marzena Ciechomska Dr Caroline Wilson Emeritus Professor Drew Rowan Professor John Robinson Dr Andrew Knight et al. | Examination of the ability of autoreactive B cells to acquire and present the rheumatoid arthritis candidate autoantigen, aggrecan, from a non-internalizable surface | 2010 |
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Dr Marzena Ciechomska Professor Thomas Lennard Emeritus Professor John Kirby Dr Andrew Knight
| The role of B cells in the induction of anti-tumour immunity | 2008 |
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