Dr Marzena Ciechomska Dr Steven O'Reilly Professor Fiona Oakley Professor Jaap van Laar
| Histone Demethylation and Toll-like Receptor 8-Dependent Cross-Talk in Monocytes Promotes Transdifferentiation of Fibroblasts in Systemic Sclerosis Via Fra-2 | 2016 |
|
Dr Steven O'Reilly Dr Marzena Ciechomska Dr Nicola Fullard Professor Jaap van Laar
| IL-13 mediates collagen deposition via STAT6 and microRNA-135b: a role for epigenetics | 2016 |
|
Professor Jaap van Laar
| Long-term effects of secukinumab on MRI findings in relation to clinical efficacy in subjects with active ankylosing spondylitis: an observational study | 2016 |
|
Dr Marzena Ciechomska Professor Jaap van Laar Dr Steven O'Reilly
| Current frontiers in systemic sclerosis pathogenesis | 2015 |
|
Professor Jaap van Laar
| A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility | 2014 |
|
Dr Marzena Ciechomska Dr Steven O'Reilly Professor Jaap van Laar
| A novel role of MIR-29a in inhibition of TAB1-mediated timp-1 production in dermal fibroblasts: implication for SSC pathogenesis | 2014 |
|
Professor Jaap van Laar Dr Bridget Griffiths
| Autologous Hematopoietic Stem Cell Transplantation vs Intravenous Pulse Cyclophosphamide in Diffuse Cutaneous Systemic Sclerosis A Randomized Clinical Trial | 2014 |
|
Dr Marzena Ciechomska Professor Jaap van Laar Dr Steven O'Reilly
| Emerging role of epigenetics in systemic sclerosis pathogenesis | 2014 |
|
Dr Steven O'Reilly Professor Jaap van Laar
| IL-6 trans signalling drives collagen via an epigenetic mechanism mediated through SMAD3 | 2014 |
|
Dr Steven O'Reilly Dr Marzena Ciechomska Rachel Cant Professor Jaap van Laar
| Interleukin-6 (IL-6) Trans Signaling Drives a STAT3-dependent Pathway That Leads to Hyperactive Transforming Growth Factor-beta (TGF-beta) Signaling Promoting SMAD3 Activation and Fibrosis via Gremlin Protein | 2014 |
|
Gill Wheater Dr Stephen Tuck Dr Harish Datta Professor Jaap van Laar
| Method-specific differences in beta-isomerised carboxy-terminal cross-linking telopeptide of type I collagen and procollagen type I amino-terminal propeptide using two fully automated immunoassays | 2014 |
|
Dr Steven O'Reilly Rachel Cant Dr Marzena Ciechomska Professor Fiona Oakley Professor Sophie Hambleton et al. | Serum Amyloid A (SAA) induces IL-6 in dermal fibroblasts via TLR2, IRAK4 and NF-κB | 2014 |
|
Professor Jaap van Laar
| 2013 Classification Criteria for Systemic Sclerosis An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative | 2013 |
|
Professor Jaap van Laar
| 2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League Against Rheumatism collaborative initiative | 2013 |
|
Professor Jaap van Laar
| A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci | 2013 |
|
Dr Steven O'Reilly Rachel Cant Dr Marzena Ciechomska Professor Jaap van Laar
| Acute Serum Amyloid A (A-SSA) Induces TIMP-1 in Dermal Fibroblasts that is Mediated Via a TLR-Dependent and Formyl Receptor-Independent Pathway | 2013 |
|
Professor Jaap van Laar
| Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: a randomised, double-blind, placebo-controlled trial | 2013 |
|
Professor Jaap van Laar
| Autologous HSCT for systemic sclerosis | 2013 |
|
Professor Jaap van Laar Dr Anja Krippner-Heidenreich
| CLL cells are resistant to smac mimetics because of an inability to form a ripoptosome complex | 2013 |
|
Dr Marzena Ciechomska Professor Jaap van Laar
| Role of FRA-2 in TLR8-Mediated TIMP-1 Production in Systemic Sclerosis | 2013 |
|
Dr Marzena Ciechomska Dr Bridget Griffiths Professor Sophie Hambleton Professor Jaap van Laar
| The Role of Serum Factors and Toll-Like Receptor Signaling in the Induction of Profibrotic TIMP-1 by Monocytes in Systemic Sclerosis | 2013 |
|
Dr Steven O'Reilly Professor Jaap van Laar
| Tyrosine Kinase Induced Fibrosis: Implications for Systemic Sclerosis | 2013 |
|
Professor Jaap van Laar
| Update on Stem Cell Transplantation for Systemic Sclerosis: Recent Trial Results | 2013 |
|
Dr Steven O'Reilly Dr Venetia Bigley Professor Matthew Collin Dr Anja Krippner-Heidenreich Professor Jaap van Laar et al. | Tumor necrosis factor-alpha co-activated T-cells support a profibrotic cytokine milieu on cost of IL-10 expression in patients with systemic sclerosis | 2012 |
|