Publications by Professor Jaap van Laar - ePrints

Browsing publications by Professor Jaap van Laar.

Newcastle Authors	Title	Year
Dr Marzena Ciechomska Dr Steven O'Reilly Professor Fiona Oakley Professor Jaap van Laar	Histone Demethylation and Toll-like Receptor 8-Dependent Cross-Talk in Monocytes Promotes Transdifferentiation of Fibroblasts in Systemic Sclerosis Via Fra-2	2016
Dr Steven O'Reilly Dr Marzena Ciechomska Dr Nicola Fullard Professor Jaap van Laar	IL-13 mediates collagen deposition via STAT6 and microRNA-135b: a role for epigenetics	2016
Professor Jaap van Laar	Long-term effects of secukinumab on MRI findings in relation to clinical efficacy in subjects with active ankylosing spondylitis: an observational study	2016
Dr Marzena Ciechomska Professor Jaap van Laar Dr Steven O'Reilly	Current frontiers in systemic sclerosis pathogenesis	2015
Professor Jaap van Laar	A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility	2014
Dr Marzena Ciechomska Dr Steven O'Reilly Professor Jaap van Laar	A novel role of MIR-29a in inhibition of TAB1-mediated timp-1 production in dermal fibroblasts: implication for SSC pathogenesis	2014
Professor Jaap van Laar Dr Bridget Griffiths	Autologous Hematopoietic Stem Cell Transplantation vs Intravenous Pulse Cyclophosphamide in Diffuse Cutaneous Systemic Sclerosis A Randomized Clinical Trial	2014
Dr Marzena Ciechomska Professor Jaap van Laar Dr Steven O'Reilly	Emerging role of epigenetics in systemic sclerosis pathogenesis	2014
Dr Steven O'Reilly Professor Jaap van Laar	IL-6 trans signalling drives collagen via an epigenetic mechanism mediated through SMAD3	2014
Dr Steven O'Reilly Dr Marzena Ciechomska Rachel Cant Professor Jaap van Laar	Interleukin-6 (IL-6) Trans Signaling Drives a STAT3-dependent Pathway That Leads to Hyperactive Transforming Growth Factor-beta (TGF-beta) Signaling Promoting SMAD3 Activation and Fibrosis via Gremlin Protein	2014
Gill Wheater Dr Stephen Tuck Dr Harish Datta Professor Jaap van Laar	Method-specific differences in beta-isomerised carboxy-terminal cross-linking telopeptide of type I collagen and procollagen type I amino-terminal propeptide using two fully automated immunoassays	2014
Dr Steven O'Reilly Rachel Cant Dr Marzena Ciechomska Professor Fiona Oakley Professor Sophie Hambleton et al.	Serum Amyloid A (SAA) induces IL-6 in dermal fibroblasts via TLR2, IRAK4 and NF-κB	2014
Professor Jaap van Laar	2013 Classification Criteria for Systemic Sclerosis An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative	2013
Professor Jaap van Laar	2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League Against Rheumatism collaborative initiative	2013
Professor Jaap van Laar	A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci	2013
Dr Steven O'Reilly Rachel Cant Dr Marzena Ciechomska Professor Jaap van Laar	Acute Serum Amyloid A (A-SSA) Induces TIMP-1 in Dermal Fibroblasts that is Mediated Via a TLR-Dependent and Formyl Receptor-Independent Pathway	2013
Professor Jaap van Laar	Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: a randomised, double-blind, placebo-controlled trial	2013
Professor Jaap van Laar	Autologous HSCT for systemic sclerosis	2013
Professor Jaap van Laar Dr Anja Krippner-Heidenreich	CLL cells are resistant to smac mimetics because of an inability to form a ripoptosome complex	2013
Dr Marzena Ciechomska Professor Jaap van Laar	Role of FRA-2 in TLR8-Mediated TIMP-1 Production in Systemic Sclerosis	2013
Dr Marzena Ciechomska Dr Bridget Griffiths Professor Sophie Hambleton Professor Jaap van Laar	The Role of Serum Factors and Toll-Like Receptor Signaling in the Induction of Profibrotic TIMP-1 by Monocytes in Systemic Sclerosis	2013
Dr Steven O'Reilly Professor Jaap van Laar	Tyrosine Kinase Induced Fibrosis: Implications for Systemic Sclerosis	2013
Professor Jaap van Laar	Update on Stem Cell Transplantation for Systemic Sclerosis: Recent Trial Results	2013
Dr Steven O'Reilly Dr Venetia Bigley Professor Matthew Collin Dr Anja Krippner-Heidenreich Professor Jaap van Laar et al.	Tumor necrosis factor-alpha co-activated T-cells support a profibrotic cytokine milieu on cost of IL-10 expression in patients with systemic sclerosis	2012