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Browsing publications by Professor Jaap van Laar.

Newcastle AuthorsTitleYearFull text
Dr Marzena Ciechomska
Dr Steven O'Reilly
Professor Fiona Oakley
Professor Jaap van Laar
Histone Demethylation and Toll-like Receptor 8-Dependent Cross-Talk in Monocytes Promotes Transdifferentiation of Fibroblasts in Systemic Sclerosis Via Fra-22016
Dr Steven O'Reilly
Dr Marzena Ciechomska
Dr Nicola Fullard
Professor Jaap van Laar
IL-13 mediates collagen deposition via STAT6 and microRNA-135b: a role for epigenetics2016
Professor Jaap van Laar
Long-term effects of secukinumab on MRI findings in relation to clinical efficacy in subjects with active ankylosing spondylitis: an observational study2016
Dr Marzena Ciechomska
Professor Jaap van Laar
Dr Steven O'Reilly
Current frontiers in systemic sclerosis pathogenesis2015
Professor Jaap van Laar
A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility2014
Dr Marzena Ciechomska
Dr Steven O'Reilly
Professor Jaap van Laar
A novel role of MIR-29a in inhibition of TAB1-mediated timp-1 production in dermal fibroblasts: implication for SSC pathogenesis2014
Professor Jaap van Laar
Dr Bridget Griffiths
Autologous Hematopoietic Stem Cell Transplantation vs Intravenous Pulse Cyclophosphamide in Diffuse Cutaneous Systemic Sclerosis A Randomized Clinical Trial2014
Dr Marzena Ciechomska
Professor Jaap van Laar
Dr Steven O'Reilly
Emerging role of epigenetics in systemic sclerosis pathogenesis2014
Dr Steven O'Reilly
Professor Jaap van Laar
IL-6 trans signalling drives collagen via an epigenetic mechanism mediated through SMAD32014
Dr Steven O'Reilly
Dr Marzena Ciechomska
Rachel Cant
Professor Jaap van Laar
Interleukin-6 (IL-6) Trans Signaling Drives a STAT3-dependent Pathway That Leads to Hyperactive Transforming Growth Factor-beta (TGF-beta) Signaling Promoting SMAD3 Activation and Fibrosis via Gremlin Protein2014
Gill Wheater
Dr Stephen Tuck
Dr Harish Datta
Professor Jaap van Laar
Method-specific differences in beta-isomerised carboxy-terminal cross-linking telopeptide of type I collagen and procollagen type I amino-terminal propeptide using two fully automated immunoassays2014
Dr Steven O'Reilly
Rachel Cant
Dr Marzena Ciechomska
Professor Fiona Oakley
Dr Sophie Hambleton
et al.
Serum Amyloid A (SAA) induces IL-6 in dermal fibroblasts via TLR2, IRAK4 and NF-κB2014
Professor Jaap van Laar
2013 Classification Criteria for Systemic Sclerosis An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative2013
Professor Jaap van Laar
2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League Against Rheumatism collaborative initiative2013
Professor Jaap van Laar
A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci2013
Dr Steven O'Reilly
Rachel Cant
Dr Marzena Ciechomska
Professor Jaap van Laar
Acute Serum Amyloid A (A-SSA) Induces TIMP-1 in Dermal Fibroblasts that is Mediated Via a TLR-Dependent and Formyl Receptor-Independent Pathway2013
Professor Jaap van Laar
Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: a randomised, double-blind, placebo-controlled trial2013
Professor Jaap van Laar
Autologous HSCT for systemic sclerosis2013
Professor Jaap van Laar
Dr Anja Krippner-Heidenreich
CLL cells are resistant to smac mimetics because of an inability to form a ripoptosome complex2013
Dr Marzena Ciechomska
Professor Jaap van Laar
Role of FRA-2 in TLR8-Mediated TIMP-1 Production in Systemic Sclerosis2013
Dr Marzena Ciechomska
Dr Bridget Griffiths
Dr Sophie Hambleton
Professor Jaap van Laar
The Role of Serum Factors and Toll-Like Receptor Signaling in the Induction of Profibrotic TIMP-1 by Monocytes in Systemic Sclerosis2013
Dr Steven O'Reilly
Professor Jaap van Laar
Tyrosine Kinase Induced Fibrosis: Implications for Systemic Sclerosis2013
Professor Jaap van Laar
Update on Stem Cell Transplantation for Systemic Sclerosis: Recent Trial Results2013
Dr Steven O'Reilly
Dr Venetia Bigley
Professor Matthew Collin
Dr Anja Krippner-Heidenreich
Professor Jaap van Laar
et al.
Tumor necrosis factor-alpha co-activated T-cells support a profibrotic cytokine milieu on cost of IL-10 expression in patients with systemic sclerosis2012