Publications by Dr Dennis Lendrem - ePrints

Browsing publications by Dr Dennis Lendrem.

Newcastle Authors	Title	Year
Jessica Tarn Dr Dennis Lendrem John Casement Professor Fai Ng	What can patients tell us in Sjögren’s syndrome?	2024
Jessica Tarn John Casement Lauren Scott Karl Wood Dr Dennis Lendrem et al.	Examining the biological pathways underlying clinical heterogeneity in Sjogren's syndrome: Proteomic and network analysis	2023
Jessica Tarn Emmanuella Traianos Amy Collins Dr Myrto Stylianou Dr Jehill Parikh et al.	The Effects Of Non-Invasive Vagus Nerve Stimulation on Fatigue In Participants With Primary Sjögren's Syndrome	2023
Jessica Tarn Dr Dennis Lendrem Professor Michael Barnes John Casement Professor Fai Ng et al.	Comorbidities in the UK Primary Sjögren’s Syndrome Registry	2022
Dr Ken Baker Dr Dennis Lendrem Adam Scadeng Dr Ben Thompson Dr Arthur Pratt et al.	Erratum to "Predicting drug-free remission in rheumatoid arthritis: A prospective interventional cohort study" [J. Autoimmun. 105 (December 2019) 102298	2022
Dr Faye Cooles Jessica Tarn Dr Dennis Lendrem Najib Naamane Alice Lin et al.	Interferon-α-mediated therapeutic resistance in early rheumatoid arthritis implicates epigenetic reprogramming	2022
Dr Alice Banks Dr Colette Whitfield Dr Steven Brown Professor David Fulton Dr Dennis Lendrem et al.	Key reaction components affect the kinetics and performance robustness of cell-free protein synthesis reactions	2022
Jessica Tarn Dr Dennis Lendrem Dr Clare Lendrem Ben Hargreaves Professor Fai Ng et al.	Primary Sjögren's syndrome: Longitudinal real-world, observational data on health-related quality of life	2022
Professor John Isaacs Sarah Brockbank Dr Ayako Pedersen Professor Catharien Hilkens Dr Amy Anderson et al.	RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients	2022
Dr Dennis Lendrem Jessica Tarn Professor James Wason Professor Fai Ng	Why stratification is important in primary Sjögren’s syndrome	2022
Dr Ken Baker Dr Aidan Hanrath Dr Ina Schim van der Loeff Dr Dalvir Bajwa Dr Clare Lendrem et al.	COVID-19 Management in a UK NHS Foundation Trust with a High Consequence Infectious Diseases Centre: A Retrospective Analysis	2021
Dr Dennis Lendrem Professor John Isaacs	Influenza vaccination and interruption of methotrexate in adult patients in the COVID-19 era: an ongoing dilemma	2021
Dr Alexis Collins Dr Dennis Lendrem Professor James Wason Jessica Tarn Dr Nadia Howard-Tripp et al.	Revisiting the JOQUER trial: stratification of primary Sjögren’s syndrome and the clinical and interferon response to hydroxychloroquine	2021
Dr Andrew Porter Dr Dennis Lendrem Professor John Isaacs	Robust optimization of SWATH-MS workflow for human blood serum proteome analysis using a quality by design approach	2021
Dr Aidan Hanrath Dr Ina Schim van der Loeff Dr Dennis Lendrem Dr Ken Baker Dr David Price et al.	SARS-CoV-2 Testing of 11,884 Healthcare Workers at an Acute NHS Hospital Trust in England: A Retrospective Analysis	2021
Dr Kate Hackett Dr Dennis Lendrem Dr Clare Abley	Exploring medicines reconciliation in the emergency assessment unit: staff perceptions and actual waiting times.	2020
Dr Ewan Hunter Dr David Price Dr Ina Schim van der Loeff Dr Ken Baker Dr Dennis Lendrem et al.	First experience of COVID-19 screening of health-care workers in England	2020
Jessica Tarn Dr Dennis Lendrem Professor John Isaacs	In search of pathobiological endotypes: a systems approach to early rheumatoid arthritis	2020
Dr Ken Baker Benjamin Thompson Dr Dennis Lendrem Adam Scadeng Dr Arthur Pratt et al.	Lack of association between clinical and ultrasound measures of disease activity in rheumatoid arthritis remission	2020
Dr Dennis Lendrem Dr Clare Lendrem Dr Arthur Pratt Professor John Isaacs Professor David Jones et al.	Schrödinger's pipeline and the outsourcing of pharmaceutical innovation	2020
Emmanuella Traianos Dr James Locke Dr Dennis Lendrem Ben Hargreaves Jessica Tarn et al.	Serum CXCL₁₃ levels are associated with lymphoma risk and lymphoma occurrence in primary Sjögren’s syndrome	2020
Dr Clare Lendrem Dr Dennis Lendrem Dr Arthur Pratt Najib Naamane Dr Peter McMeekin et al.	Between a ROC and a hard place: Teaching prevalence plots to understand real world biomarker performance in the clinic	2019
Dr Harold Fellermann Dr Benjamin Shirt-Ediss Dr Jurek Kozyra Matt Linsley Dr Dennis Lendrem et al.	Design of experiments and the virtual PCR simulator: An online game for pharmaceutical scientists and biotechnologists	2019
Dr Amy Anderson Dr Nicola Maney Dr Dennis Lendrem Julie Diboll Dr Philip Brown et al.	Expression of STAT3-regulated genes in circulating CD4+ T cells discriminates rheumatoid arthritis independently of clinical parameters in early arthritis	2019
Kristen Davies Dr Kamran Mirza Jessica Tarn Dr Nadia Howard-Tripp Dr Dennis Lendrem et al.	Fatigue in primary Sjögren’s syndrome (pSS) is associated with lower levels of proinflammatory cytokines: a validation study	2019
Dr Dennis Lendrem Professor Fai Ng Dr Kate Hackett	Managing fatigue in patients with primary Sjögren’s syndrome: challenges and solutions	2019
Dr Dennis Lendrem Professor Fai Ng Dr Kate Hackett	Managing fatigue in patients with primary Sjögren's syndrome.	2019
Dr Kate Hackett Kristen Davies Jessica Tarn Ben Hargreaves Dr Dennis Lendrem et al.	Pain and depression are associated with both physical and mental fatigue independently of comorbidities and medications in primary Sjögren's syndrome	2019
Dr Ken Baker Andrew Skelton Dr Dennis Lendrem Adam Scadeng Dr Ben Thompson et al.	Predicting drug-free remission in rheumatoid arthritis: A prospective interventional cohort study	2019
Kundan Iqbal Dr Dennis Lendrem Ben Hargreaves Professor John Isaacs Dr Ben Thompson et al.	Routine musculoskeletal ultrasound findings impact diagnostic decisions maximally in autoantibody-seronegative early arthritis patients	2019
Professor Fai Ng Dr Dennis Lendrem Professor Mike Trenell	Supervised walking improves cardiorespiratory fitness, exercise tolerance, and fatigue in women with primary Sjögren’s syndrome: a randomized-controlled trial	2019
Jessica Tarn Dr Nadia Howard-Tripp Dr Dennis Lendrem Andrew Skelton Dr Katherine James et al.	Symptom-based stratification of patients with primary Sjögren's syndrome: multi-dimensional characterisation of international observational cohorts and reanalyses of randomised clinical trials	2019
Dr Nishanthi Thalayasingam Andrew Skelton Dr Amy Anderson Alex Clark Julie Diboll et al.	CD4+ and B lymphocyte expression quantitative traits at rheumatoid arthritis risk loci in untreated early arthritis: implications for causal gene identification	2018
Professor Fai Ng Dr Katherine James Dr Bridget Griffiths Dr David Coady Dr Steven Young-Min et al.	Comparison of ESSDAI and ClinESSDAI in potential optimisation of trial outcomes in primary Sjögren's syndrome: Examination of data from the UK Primary Sjögren's Syndrome Registry	2018
Dr Ken Baker Dr Ben Thompson Dr Dennis Lendrem Dr Arthur Pratt Professor John Isaacs et al.	Lack of association between clinical and ultrasound measures of disease activity in rheumatoid arthritis clinical remission: a cross-sectional analysis	2018
Dr Ken Baker Dr Dennis Lendrem Dr Ben Thompson Dr Arthur Pratt Professor John Isaacs et al.	Predictors of drug-free remission in rheumatoid arthritis: results from the prospective Biomarkers of Remission in Rheumatoid Arthritis (BioRRA) Study	2018
Shereen Al-Ali Jessica Tarn Dr Dennis Lendrem Dr Bridget Griffiths Professor Fai Ng et al.	Systemic interferon type I and type II signatures in primary Sjögren’s syndrome reveal differences in biological disease activity	2018
Sarah Brockbank Dr Carl Goodyear Dr Ayako Pedersen Professor John Isaacs Philip Stocks et al.	The RA-MAP Consortium: a working model for academia-industry collaboration	2018
Dr Dennis Lendrem Emerita Professor Julia Newton Dr Katie Hackett	A scoping exercise to gauge the incidence of early post-stroke fatigue for patients at Newcastle community stroke services	2017
Dr Faye Cooles Dr Amy Anderson Dr Dennis Lendrem Julie Norris Dr Arthur Pratt et al.	The interferon gene signature is increased in patients with early treatment-naive rheumatoid arthritis and predicts a poorer response to initial therapy	2017
Dr Nadia Howard-Tripp Jessica Tarn Dr Colin Gillespie Dr Dennis Lendrem Dr Bridget Griffiths et al.	A Cytokine-Mediated Biological Basis for Fatigue in Primary Sjögren’s Syndrome	2016
Dr Arthur Pratt Dr Dennis Lendrem Ben Hargreaves Professor John Isaacs	Components of treatment delay in rheumatoid arthritis differ according to autoantibody status: validation of a single-centre observation using national audit data	2016
Helen Hanson Professor John Isaacs Dr Lesley Kay Dr Dennis Lendrem Dr Nicola O'Brien et al.	Experiences of staff and patients in relation to clinical research recruitment and involvement: a qualitative study	2016
Jessica Tarn Andini Natasari Colin Gillespie Sheryl Mitchell Dr Katie Hackett et al.	Fatigue in primary Sjögren's syndrome is associated with lower levels of proinflammatory cytokines	2016
Dr Arthur Pratt Dr Amy Anderson Julie Diboll Andrew Skelton Dr Dennis Lendrem et al.	Identification of novel expression quantitative trait loci in CD4+ T cells of untreated early arthritis patients	2016
Dr Katie Hackett Dr Dennis Lendrem Ben Hargreaves Vicki Strassheim Dr Zoe Gotts et al.	Objective Improvement in Fatigue Scores for Primary Sjögren’s Patients Receiving a Tailored Multidisciplinary Fatigue Intervention in a Generic Fatigue Clinic	2016
Dr Dennis Lendrem Dr Clare Lendrem Matt Linsley Ruth Rowland-Jones Fabio D'Agostino et al.	Teaching Examples for the Design of Experiments: Geographical Sensitivity and the Self-Fulfilling Prophecy	2016
Dr Ken Baker Benjamin Thompson Dr Dennis Lendrem Dr Arthur Pratt Professor John Isaacs et al.	Ultrasound measures of synovitis are independent of clinical parameters in the setting of rheumatoid arthritis remission: a cross-sectional analysis.	2016
Dr Katie Hackett Dr Dennis Lendrem Dr Tim Rapley Dr Katherine Deane Vincent Deary et al.	"Doing Every-Day Life" with Primary Sjogren's Syndrome: Factors Predicting Difficulties Performing Daily Activities and Taking on Life Roles	2015
Dr Katherine James Shereen Al-Ali Jessica Tarn Dr Simon Cockell Dr Colin Gillespie et al.	A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren’s Syndrome	2015
Ben Hargreaves Dr Dennis Lendrem Vicki Hindmarsh Claire Humphrey Sheryl Mitchell et al.	Assignable Causes for Fatigue in Primary Sjögren’s Syndrome: Data from the UK Primary Sjögren’s Syndrome Registry	2015
Dr Katie Hackett Dr Dennis Lendrem Dr James Frith Dr Tim Rapley Vincent Deary et al.	Cognitive Impairment in Primary Sjögren’s Syndrome	2015
Dr Katie Hackett Dr Dennis Lendrem Dr James Frith Dr Tim Rapley Vincent Deary et al.	Cognitive Symptoms are Common in Primary Sjogren's Syndrome and are Associated with Anxiety	2015
Dr Katie Hackett Dr Dennis Lendrem Dr James Frith Dr Tim Rapley Vincent Deary et al.	Cognitive symptoms are common in primary Sjögren's syndrome and are associated with anxiety	2015
Dr Arthur Pratt Ben Hargreaves Dr Dennis Lendrem Professor John Isaacs	Components of treatment delay in rheumatoid arthritis differ according to autoantibody status	2015
Dr Dennis Lendrem Sheryl Mitchell Dr Peter McMeekin Dr Katie Hackett Sarah Bowman et al.	Do the EULAR Sjögren’s syndrome outcome measures correlate with health status in primary Sjögren’s syndrome?	2015
Dr Katherine Crossland Dr Chun Chan Tariq AlShehri Dr Mario Abinun Professor Andrew Gennery et al.	Gain-of-function STAT1 mutations impair STAT3 activity in patients with Chronic Mucocutaneous Candidiasis (CMC)	2015
Dr Dennis Lendrem Dr Clare Lendrem Dr David Woods Ruth Rowland-Jones Professor John Isaacs et al.	Lost in Space: Design of Experiments and Scientific Exploration in a Hogarth Universe	2015
Jessica Tarn Dr Dennis Lendrem Dr Colin Gillespie Shereen Al-Ali Dr Bridget Griffiths et al.	Patient Sub-Phenotyping in Primary Sjogren's Syndrome	2015
Dr Dennis Lendrem	Pharmaceutical R&D Productivity: Be Careful What You Wish For	2015
Dr Dennis Lendrem Dr Clare Lendrem Professor John Isaacs	Progression-seeking bias and rational optimism in research and development	2015
Dr Faye Cooles Dr Arthur Pratt Dr Dennis Lendrem Professor Fai Ng Dr Terry Aspray et al.	Retrospective analysis of the role of serum vitamin D in early rheumatic disease	2015
Dr Arthur Pratt Dr Amy Anderson Dr Dennis Lendrem Julie Diboll Ben Hargreaves et al.	STAT3-regulated gene expression in circulating CD4+ T cells discriminates RA patients independently of clinical parameters in early arthritis: a validation study.	2015
Dr Arthur Pratt Dr Amy Anderson Julie Diboll Andrew Skelton Ben Hargreaves et al.	The Importance of IL-6-STAT₃ Mediated Activation of Circulating CD4⁺ T Cells in the Pathogenesis of Early Seronegative Rheumatoid Arthritis: A Validation Study	2015
Dr Dennis Lendrem Dr Clare Lendrem Professor John Isaacs	Why is it hard to terminate failing projects in pharmaceutical R&D?	2015
Dr Dennis Lendrem Andrew Gray Professor John Isaacs	Christmas 2014: Going to Extremes. The Darwin Awards: sex differences in idiotic behaviour	2014
Dr Katie Hackett Emerita Professor Julia Newton Dr Katherine Deane Dr Tim Rapley Vincent Deary et al.	Developing a service user informed intervention to improve participation and ability to perform daily activities in primary Sjӧgren’s syndrome: a mixed methods study protocol	2014
Dr Katherine Crossland Dr Mario Abinun Professor Andrew Gennery Professor Jelena Mann Dr Dennis Lendrem et al.	Gain-of-function stat1 mutation impairs stat3 function predisposing to chronic mucocutaneous candidiasis	2014
Dr Dennis Lendrem Sheryl Mitchell Dr Peter McMeekin Dr Bridget Griffiths Professor Fai Ng et al.	Health-related utility values of patients with primary Sjögren's syndrome and its predictors	2014
Dr Dennis Lendrem Dr Clare Lendrem Professor John Isaacs	R&D Productivity Rides Again?	2014
Dr Faye Cooles Dr Arthur Pratt Dr Dennis Lendrem Professor Fai Ng Dr Terry Aspray et al.	Retrospective analysis of the role of serum vitamin D in early rheumatic disease	2014
Dr Dennis Lendrem Andrew Gray Professor John Isaacs	The Darwin Awards: Gender Differences in Idiotic Behaviour	2014
Dr Dennis Lendrem Dr Clare Lendrem	The Development Speed Paradox: Can increasing development speed reduce R&D productivity?	2014
Dr Dennis Lendrem	The Norm Chronicles: stories and numbers about danger by Michael Blastland and David Spiegelhalter [Book review]	2014
Dr Katherine James Dr Dennis Lendrem Sheryl Mitchell Vicki Hindmarsh Dr David Coady et al.	The UK Primary Sjögren’s Syndrome Registry (UKPSSR): A Valuable Resource for Future Sjögren’s Syndrom Research	2014
Dr Karthik Balasubramaniam Dr Girish Viswanathan Andini Natasari Jessica Tarn Dr Dennis Lendrem et al.	Assessment of blood clot formation and platelet receptor function ex vivo in patients with primary Sjögren’s syndrome	2013
Professor Fai Ng Andrew Carr Dr Ian Corbett Professor Marco Carrozzo Dr Dennis Lendrem et al.	Association of genes in the NF-κB pathway with antibody-positive primary Sjögren's syndrome.	2013
Dr Dennis Lendrem	Bad pharma: how drug companies mislead doctors and harm patients by Ben Goldacre	2013
Andini Natasari Jessica Tarn Dr Dennis Lendrem Professor Fai Ng	Exploring the biological basis of fatigue using primary Sjögren's syndrome as a disease model	2013
Dr Dennis Lendrem Dr Clare Lendrem	Torching the Haystack: Modelling fast-fail strategies in drug development	2013
Emerita Professor Julia Newton Dr James Frith Danielle Powell Dr Katie Hackett Katharine Wilton et al.	Autonomic symptoms are common and are associated with overall symptom burden and disease activity in primary Sjögren's syndrome	2012
Dr Dennis Lendrem Sheryl Mitchell Sarah Bowman Dr Bridget Griffiths Heather Foggo et al.	Evaluating health status of 620 patients with primary sjögren’s syndrome using EQ-5D	2012
Professor Fai Ng Dr Dennis Lendrem Sarah Bowman	Evaluating health status of 620 patients with primary Sjögren's syndrome using EQ-5D	2012
Professor Fai Ng Dr Dennis Lendrem	How good are the EULAR Sj ögren's syndrome disease activity index (ESSDAI), and EULAR Sj ögren's syndrome patients reported index (ESSPRI) in predicting health status in primary Sj ögren's syndrome? Normal 0 false false false EN-GB X-NONE X-NONE Normal 0 false false false EN-GB X-NONE X-NONE Normal 0 false false false EN-GB X-NONE X-NONE	2012
Dr Dennis Lendrem Sheryl Mitchell Sarah Bowman Dr David Coady Dr Bridget Griffiths et al.	How good are the eular sjögren’s syndrome disease activity index, and eular sjögren’s syndrome patients reported index in predicting health status in primary sjögren’s syndrome?	2012
Dr Katie Hackett Emerita Professor Julia Newton Dr James Frith Chris Elliott Dr Dennis Lendrem et al.	Impaired functional status in primary Sjogren's syndrome	2012
Jessica Tarn Professor David Young Dr Dennis Lendrem Christine Downie Heather Foggo et al.	Serum cytokine and chemokine profiling in primary Sj ögren's syndrome Normal 0 false false false EN-GB X-NONE X-NONE	2012
Jessica Tarn Andini Natasari Sheryl Mitchell Dr Dennis Lendrem Christine Downie et al.	Soluble molecule profiling and network analysis of primary Sjogren's syndrome patient serum	2012
Sheryl Mitchell Dr David Coady Dr Bridget Griffiths Dr Dennis Lendrem Heather Foggo et al.	The clinical relevance of anti-RO52 and anti-RO60 in patients in the united kingdom primary sjögren’s syndrome registry (UKPSSR)	2012
Dr Dennis Lendrem	Statistical support to non-clinical	2002
Dr Dennis Lendrem	DOE (Design of Experiments) in Development Chemistry: Potential Obstacles	2001
Dr Dennis Lendrem	More haste, less development speed	1995
Dr Dennis Lendrem	Kinship, pheromones and reproduction	1986
Dr Dennis Lendrem	Should John McEnroe grunt?	1983