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Browsing publications by
Professor Alastair Hawkins.
Newcastle Authors
Title
Year
Full text
Paul Thompson
Professor Alastair Hawkins
Self-Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product
2020
Paul Thompson
Professor Alastair Hawkins
Hydroxylammonium derivatives for selective active-site lysine modification in the anti-virulence bacterial target DHQ1 enzyme
2019
Paul Thompson
Professor Alastair Hawkins
Synthesis of rigidified shikimic acid derivatives by ring-closing metathesis to imprint inhibitor efficacy against shikimate kinase enzyme
2019
Dr Arnaud Basle
Dr Lorraine Hewitt
Dr Alan Koh
Dr Heather Lamb
Paul Thompson
et al.
Crystal structure of NucB, a biofilm-degrading endonuclease
2018
Dr Nadia Rostami
Professor Alastair Hawkins
Dr Richard Holliday
Professor Philip Preshaw
Professor Nicholas Jakubovics
et al.
A Critical Role for Extracellular DNA in Dental Plaque Formation
2017
Paul Thompson
Professor Alastair Hawkins
Reducing the Flexibility of Type II Dehydroquinase for Inhibition: A Fragment-Based Approach and Molecular Dynamics Study
2017
Dr David Wilkinson
Hua Lin
Sarah Charlton
Dr Adrian Falconer
Dr Craig Bullock
et al.
The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: Molecular mechanisms and implications for extracellular matrix turnover
2017
Paul Thompson
Professor Alastair Hawkins
Freezing the Dynamic Gap for Selectivity: Motion-Based Design of Inhibitors of the Shikimate Kinase Enzyme
2016
Paul Thompson
Professor Alastair Hawkins
Frontispiece: Freezing the Dynamic Gap for Selectivity: Motion-Based Design of Inhibitors of the Shikimate Kinase Enzyme
2016
Paul Thompson
Professor Alastair Hawkins
Targeting the Motion of Shikimate Kinase: Development of Competitive Inhibitors that Stabilize an Inactive Open Conformation of the Enzyme
2016
Paul Thompson
Professor Alastair Hawkins
Chemical Modification of a Dehydratase Enzyme Involved in Bacterial Virulence by an Ammonium Derivative: Evidence of its Active Site Covalent Adduct
2015