Paul Thompson
Professor Alastair Hawkins
| Self-Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product | 2020 |
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Paul Thompson
Professor Alastair Hawkins
| Hydroxylammonium derivatives for selective active-site lysine modification in the anti-virulence bacterial target DHQ1 enzyme | 2019 |
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Paul Thompson
Professor Alastair Hawkins
| Synthesis of rigidified shikimic acid derivatives by ring-closing metathesis to imprint inhibitor efficacy against shikimate kinase enzyme | 2019 |
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Dr Arnaud Basle
Dr Lorraine Hewitt
Dr Alan Koh
Dr Heather Lamb
Paul Thompson
et al. | Crystal structure of NucB, a biofilm-degrading endonuclease | 2018 |
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Dr Nadia Rostami
Professor Alastair Hawkins
Dr Richard Holliday
Professor Philip Preshaw
Professor Nicholas Jakubovics
et al. | A Critical Role for Extracellular DNA in Dental Plaque Formation | 2017 |
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Paul Thompson
Professor Alastair Hawkins
| Reducing the Flexibility of Type II Dehydroquinase for Inhibition: A Fragment-Based Approach and Molecular Dynamics Study | 2017 |
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Dr David Wilkinson
Hua Lin
Sarah Charlton
Dr Adrian Falconer
Dr Craig Bullock
et al. | The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: Molecular mechanisms and implications for extracellular matrix turnover | 2017 |
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Paul Thompson
Professor Alastair Hawkins
| Freezing the Dynamic Gap for Selectivity: Motion-Based Design of Inhibitors of the Shikimate Kinase Enzyme | 2016 |
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Paul Thompson
Professor Alastair Hawkins
| Frontispiece: Freezing the Dynamic Gap for Selectivity: Motion-Based Design of Inhibitors of the Shikimate Kinase Enzyme | 2016 |
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Paul Thompson
Professor Alastair Hawkins
| Targeting the Motion of Shikimate Kinase: Development of Competitive Inhibitors that Stabilize an Inactive Open Conformation of the Enzyme | 2016 |
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Paul Thompson
Professor Alastair Hawkins
| Chemical Modification of a Dehydratase Enzyme Involved in Bacterial Virulence by an Ammonium Derivative: Evidence of its Active Site Covalent Adduct | 2015 |
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