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Browsing publications by Paul Thompson.

Newcastle AuthorsTitleYearFull text
Paul Thompson
Professor Alastair Hawkins
Self-Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product2020
Dr Miguel Velazquez
Paul Thompson
The role of CAPG in molecular communication between the embryo and the uterine endometrium: Is its function conserved in species with different implantation strategies?2020
Paul Thompson
Professor Alastair Hawkins
Hydroxylammonium derivatives for selective active-site lysine modification in the anti-virulence bacterial target DHQ1 enzyme2019
Paul Thompson
Professor Alastair Hawkins
Synthesis of rigidified shikimic acid derivatives by ring-closing metathesis to imprint inhibitor efficacy against shikimate kinase enzyme2019
Dr Arnaud Basle
Dr Lorraine Hewitt
Dr Alan Koh
Dr Heather Lamb
Paul Thompson
et al.
Crystal structure of NucB, a biofilm-degrading endonuclease2018
Dr David Wilkinson
Angie Habgood
Dr Heather Lamb
Paul Thompson
Professor Alastair Hawkins
et al.
Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms2017
Paul Thompson
Professor Alastair Hawkins
Reducing the Flexibility of Type II Dehydroquinase for Inhibition: A Fragment-Based Approach and Molecular Dynamics Study2017
Dr David Wilkinson
Hua Lin
Sarah Charlton
Dr Adrian Falconer
Dr Craig Bullock
et al.
The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: Molecular mechanisms and implications for extracellular matrix turnover2017
Paul Thompson
Professor Alastair Hawkins
Freezing the Dynamic Gap for Selectivity: Motion-Based Design of Inhibitors of the Shikimate Kinase Enzyme2016
Paul Thompson
Professor Alastair Hawkins
Frontispiece: Freezing the Dynamic Gap for Selectivity: Motion-Based Design of Inhibitors of the Shikimate Kinase Enzyme2016
Paul Thompson
Professor Alastair Hawkins
Study of the Phosphoryl-Transfer Mechanism of Shikimate Kinase by NMR Spectroscopy2016
Paul Thompson
Professor Alastair Hawkins
Targeting the Motion of Shikimate Kinase: Development of Competitive Inhibitors that Stabilize an Inactive Open Conformation of the Enzyme2016
Paul Thompson
Professor Alastair Hawkins
Chemical Modification of a Dehydratase Enzyme Involved in Bacterial Virulence by an Ammonium Derivative: Evidence of its Active Site Covalent Adduct2015
Dr Artur Rogowski
Jon Briggs
Dr Elisabeth Lowe
Dr Arnaud Basle
Carl Morland
et al.
Glycan complexity dictates microbial resource allocation in the large intestine2015
Paul Thompson
Professor Alastair Hawkins
Irreversible covalent modification of type I dehydroquinase with a stable Schiff base2015
Paul Thompson
Professor Alastair Hawkins
Exploring the Water-Binding Pocket of the Type II Dehydroquinase Enzyme in the Structure-Based Design of Inhibitors2014
Paul Thompson
Professor Alastair Hawkins
Insights into substrate binding and catalysis in bacterial type I dehydroquinase2014
Dr Heather Lamb
Paul Thompson
Professor Alastair Hawkins
Crystal structure of the dimer of two essential Salmonella typhimurium proteins, YgjD and YeaZ and calorimetric evidence for the formation of a ternary YgjD-YeaZ-YjeE complex2013
Shaun Martin
Dr Heather Lamb
Paul Thompson
Professor Penny Lovat
Professor Alastair Hawkins
et al.
Inducing apoptosis of cancer cells using small-molecule plant compounds that bind to GRP782013
Elaine Zhao
Samantha Hume
Dr Christopher Johnson
Paul Thompson
Dr Jun-yong Huang
et al.
The transcription repressor NmrA is subject to proteolysis by three Aspergillus nidulans proteases2010
Dr Heather Lamb
Paul Thompson
Dr Nick Watkins
Professor Alastair Hawkins
Functional analysis of the GTPases EngA and YhbZ encoded by Salmonella typhimurium2007
Dr Heather Lamb
Dr Alison Park
Dr Christopher Johnson
Dr Simon Cocklin
Paul Thompson
et al.
Modulation of the ligand binding properties of the transcription repressor NmrA by GATA-containing DNA and site-directed mutagenesis2004
Dr Margaret Piggott
Emeritus Professor Elaine Perry
Dr Elizabeth Marshall
Professor Ian McKeith
Mary Johnson
et al.
Nigrostriatal dopaminergic activities in dementia with Lewy bodies in relation to neuroleptic sensitivity: Comparisons with Parkinson's disease1998
Dr Clive Ballard
Professor Ian McKeith
Rebecca Harrison
Professor John O'Brien
Paul Thompson
et al.
Aspects of dementia. A detailed phenomenological comparison of complex visual hallucinations in dementia with Lewy bodies and Alzheimer's disease1997
Dr Christopher Morris
Alan Leake
Dr Michael Griffiths
Dr Heather Lamb
Andrew Brown
et al.
Molecular biology of APO E alleles in Alzheimer's and non-Alzheimer's dementias1996
Emeritus Professor Elaine Perry
Dr Elizabeth Marshall
Paul Thompson
Professor Ian McKeith
Daniel Collerton
et al.
Monoaminergic activities in Lewy body dementia: relation to hallucinosis and extrapyramidal features1993
Emeritus Professor Elaine Perry
Professor Ian McKeith
Paul Thompson
Dr Janet Kerwin
Emeritus Professor Jim Edwardson
et al.
Topography, extent, and clinical relevance of neurochemical deficits in dementia of Lewy body type, Parkinson's disease, and Alzheimer's disease1991