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Browsing publications by Dr Jack Leslie

Newcastle AuthorsTitleYearFull text
Dr Jack Leslie
Misti McCain
Professor Helen Reeves
Professor Derek Mann
Human-correlated genetic models identify precision therapy for liver cancer2025
Amy Collins
Keara Kirkness
Erik Ramon Gil
Eleni Tzortzopoulou
Daniel Geh
et al.		Precision-cut tumor slices for modeling hepatocellular carcinoma enable at-scale drug screening2025
Dr Jack Leslie
Amy Collins
Zosia Johnson
Jeremy French
Steven White
et al.		Spatial lipidomics reveals sphingolipid metabolism as anti-fibrotic target in the liver2025
Rebecca Garnham
Dr Daniel Geh
Ryan Nelson
Erik Ramon Gil
Laura Wilson
et al.		ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancer2024
Dr Toni Pringle
Erik Ramon Gil
Dr Jack Leslie
Professor Fiona Oakley
Professor Matthew Wright
et al.		Synthesis and Preclinical Evaluation of a 89Zr-labelled Human Single Chain Antibody for Non-invasive Detection of Hepatic Myofibroblasts in Acute Liver Injury2024
Dr Jack Leslie
Dr Jill Hunter
Amy Collins
Amelia Rushton
Lauren Russell
et al.		c-Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis2023
Rebecca Garnham
Dr Daniel Geh
Ryan Nelson
Erik Ramon Gil
Laura Wilson
et al.		ST3Gal1 synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancer2023
Dr Sam Orange
Dr Jack Leslie
Professor Derek Mann
The exercise IL-6 enigma in cancer2023
Adnan Ali
Dr Caroline Wilson
Dr Jack Leslie
Professor Derek Mann
Author Correction: Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer (Nature Medicine, (2019), 25, 4, (641-655), 10.1038/s41591-019-0379-5)2022
Dr Suzanne Madgwick
Dr Saimir Luli
Helene Sellier
Dr Jacqueline Butterworth
Dr Jack Leslie
et al.		Claspin haploinsufficiency leads to defects in fertility, hyperplasia and an increased oncogenic potential2022
Dr Jack Leslie
Erik Ramon Gil
Kathryn Gilroy
Dr Saimir Luli
Maja Laszczewska
et al.		CXCR2 inhibition enables NASH-HCC immunotherapy2022
Dr Daniel Geh
Dr Jack Leslie
Professor Helen Reeves
Professor Derek Mann
Neutrophils as potential therapeutic targets in hepatocellular carcinoma2022
Dr Marco Zaki
Dr Sari Alhasan
Dr Ruchi Shukla
Misti McCain
Maja Laszczewska
et al.		Sulfatase-2 from Cancer Associated Fibroblasts: An Environmental Target for Hepatocellular Carcinoma?2022
Dr Jack Leslie
Dr Hannah Paish
Amy Collins
Rebecca Scott
Abi Watson
et al.		A Mammalian Target of Rapamycin-Perilipin 3 (mTORC1-Plin3) Pathway is essential to Activate Lipophagy and Protects Against Hepatosteatosis2021
Dr Jack Leslie
Dr Emma Scott
Professor Quentin Anstee
Professor Fiona Oakley
Lipid remodelling in hepatocyte proliferation and hepatocellular carcinoma 2021
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